4.6 Article

Identification of circRNA-miRNA-mRNA regulatory network and its role in cardiac hypertrophy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Genetics & Heredity

Integrated Analysis of circRNA-miRNA-mRNA ceRNA Network in Cardiac Hypertrophy

Yang-Hao Chen et al.

Summary: This study establishes a circRNA-mediated ceRNA regulatory network associated with myocardial hypertrophy and identifies several key mRNAs, miRNAs, and circRNAs that may play a role in cardiac hypertrophy.

FRONTIERS IN GENETICS (2022)

Article Cardiac & Cardiovascular Systems

RyR2 regulates Cx43 hemichannel intracellular Ca2+-dependent activation in cardiomyocytes

Alessio Lissoni et al.

Summary: The research revealed that the activation of ryanodine receptors (RyRs) triggers unitary currents with a single-channel conductance of around 220 pS, which are significantly reduced by knocking down connexin 43 (Cx43). The study also showed that both RyR activation and intracellular Ca2+ elevation are necessary for the opening of Cx43 hemichannels.

CARDIOVASCULAR RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

Cardiac fibrosis

Nikolaos G. Frangogiannis

Summary: Myocardial fibrosis, characterized by the expansion of cardiac interstitium through deposition of extracellular matrix proteins, is a common pathophysiologic feature in various myocardial conditions. Activated fibroblasts and myofibroblasts play a central role in cardiac fibrosis, producing matrix proteins and triggering fibrogenic signalling cascades in response to stress. Immune cells, vascular cells, and cardiomyocytes can also contribute to fibrosis, while fibrotic changes may disrupt cardiac function and play a role in arrhythmogenesis.

CARDIOVASCULAR RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

Hypertrophic cardiomyopathy: the future of treatment

C. Vaughan Tuohy et al.

EUROPEAN JOURNAL OF HEART FAILURE (2020)

Review Cardiac & Cardiovascular Systems

Abnormalities in sodium current and calcium homoeostasis as drivers of arrhythmogenesis in hypertrophic cardiomyopathy

Raffaele Coppini et al.

CARDIOVASCULAR RESEARCH (2020)

Review Cell Biology

Circular RNA in Diseased Heart

Ying Wang et al.

Review Cell Biology

The expanding regulatory mechanisms and cellular functions of circular RNAs

Ling-Ling Chen

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Genetics & Heredity

Genomic analysis of circular RNAs in heart

Kunzhe Dong et al.

BMC MEDICAL GENOMICS (2020)

Article Cardiac & Cardiovascular Systems

Paradigm of Sudden Death Prevention in Hypertrophic Cardiomyopathy

Barry J. Maron et al.

CIRCULATION RESEARCH (2019)

Article Biochemistry & Molecular Biology

M-class hypertrophic cardiomyopathy cardiac actin mutations increase calcium sensitivity of regulated thin filaments

Grace Zi Teng et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Genetics & Heredity

miRNA Genetic Variants Alter Their Secondary Structure and Expression in Patients With RASopathies Syndromes

Joseane Biso de Carvalho et al.

FRONTIERS IN GENETICS (2019)

Review Cell Biology

Circular RNA in cardiovascular disease

M-Ashraf Altesha et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

Review Biochemistry & Molecular Biology

Deciphering miRNAs' Action through miRNA Editing

Marta Correia de Sousa et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Multidisciplinary Sciences

Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy

Kristina Sonnenschein et al.

SCIENTIFIC REPORTS (2019)

Review Medicine, General & Internal

Clinical Course and Management of Hypertrophic Cardiomyopathy

Barry J. Maron

NEW ENGLAND JOURNAL OF MEDICINE (2018)

News Item Biochemistry & Molecular Biology

The L-type Ca2+ channel: A mediator of hypertrophic cardiomyopathy

Helena M. Viola et al.

CHANNELS (2017)

Review Health Care Sciences & Services

An Overview of R in Health Decision Sciences

Hawre Jalal et al.

MEDICAL DECISION MAKING (2017)

Review Cardiac & Cardiovascular Systems

Role of Genetic Testing in Inherited Cardiovascular Disease A Review

Allison L. Cirino et al.

JAMA CARDIOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Hypertrophic Cardiomyopathy Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy

Ali J. Marian et al.

CIRCULATION RESEARCH (2017)

Review Cardiac & Cardiovascular Systems

Calcium Signaling and Cardiac Arrhythmias

Andrew P. Landstrom et al.

CIRCULATION RESEARCH (2017)

Review Cardiac & Cardiovascular Systems

Update on hypertrophic cardiomyopathy and a guide to the guidelines

Srijita Sen-Chowdhry et al.

NATURE REVIEWS CARDIOLOGY (2016)

Article Genetics & Heredity

ceRNA in cancer: possible functions and clinical implications

Xiaolong Qi et al.

JOURNAL OF MEDICAL GENETICS (2015)

Article Cardiac & Cardiovascular Systems

Genotype-Phenotype Correlations in Apical Variant Hypertrophic Cardiomyopathy

Eric C. Towe et al.

CONGENITAL HEART DISEASE (2015)

Article Cardiac & Cardiovascular Systems

Risk of Sudden Death and Outcome in Patients With Hypertrophic Cardiomyopathy With Benign Presentation and Without Risk Factors

Paolo Spirito et al.

AMERICAN JOURNAL OF CARDIOLOGY (2014)

Article Cell Biology

Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation

Carla J. Aguiar et al.

CELL COMMUNICATION AND SIGNALING (2014)

Article Biochemistry & Molecular Biology

circBase: a database for circular RNAs

Petar Glazar et al.

Article Medicine, General & Internal

Hypertrophic cardiomyopathy

Barry J. Maron et al.

LANCET (2013)

Article Multidisciplinary Sciences

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak et al.

NATURE (2013)

Review Cardiac & Cardiovascular Systems

Mechanisms of disease: hypertrophic cardiomyopathy

Norbert Frey et al.

NATURE REVIEWS CARDIOLOGY (2012)

Article Biochemistry & Molecular Biology

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Leonardo Salmena et al.

Review Cardiac & Cardiovascular Systems

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

Saskia Schlossarek et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)

Article Multidisciplinary Sciences

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells

Neil L. Spector et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Medicine, General & Internal

Hypertrophic cardiomyopathy - A systematic review

BJ Maron

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)