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Article
Biophysics
Oveis Pourmehran et al.
Summary: This paper examines the effect of turbulence and swirling in the inlet flow and the diameter of the nozzle on flow characteristics and particles' transport/deposition patterns in the nasal cavity and maxillary sinus. The results show that the nasal valve plays a key role in nasal resistance and the effect of turbulence at the inlet on drug delivery is negligible. Increasing flow swirl and decreasing nozzle diameter significantly improve particle deposition. The use of swirling flow and reduced nozzle diameter can increase drug delivery efficiency.
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
(2022)
Article
Mechanics
Mehrdad Khamooshi et al.
Summary: Nasal cannula oxygen therapy is a common treatment for respiratory failure, but its potential for assisted breathing needs further investigation. This study used computational fluid dynamics simulations to investigate nasal heat and mass transfer and sinus ventilation during assisted breathing under different conditions. The results showed that high-flow assisted breathing had the most impact on nasal heat flux and sinonasal ventilation, while low-flow assisted breathing had minimal effect and was considered ineffective for relevant treatment.
Article
Mechanics
Mohammad S. Islam et al.
Summary: The SARS-CoV-2 Omicron variant is highly transmissible and causes a higher mortality rate. It establishes a local infection at the extrathoracic airway level. This study developed a numerical model to analyze the transport behavior of Omicron droplets in the extrathoracic airways and found that nose inhalation is more harmful due to higher deposition rates and toxicity.
Article
Environmental Sciences
Md Rabiul Islam et al.
Summary: Airway stenosis is a global respiratory health problem caused by various factors. This study provides insights into the airflow dynamics and nanoparticle transport in multi-stenosis airways. The results show that higher velocity and wall shear stress are observed in stenosis sections, and the highest pressure is found in the mouth-throat section. The study also reveals the dependence of particle escape rate on flow rate and particle size, as well as the higher deposition efficiency in mouth-throat and stenosis sections.
Article
Chemistry, Multidisciplinary
Hana Salati et al.
Summary: This study investigated the dispersion of liquid flow through altered nasal cavities following functional endoscopic sinus surgery (FESS) using Computational Fluid Dynamics (CFD). The results demonstrated the significant impact of postoperative nasal anatomy on the flow dynamics.
PHARMACEUTICAL RESEARCH
(2022)
Article
Computer Science, Information Systems
Mohammad S. Islam et al.
Summary: This study develops a novel machine learning model to accurately predict particle deposition in the lower airways. The model reduces computational time and uses four ML regression models, with the MLP model displaying the most accurate estimates. The model predicts deposition efficiency for different particle sizes and flow rates, as well as lobe-specific efficiency for various flow rates.
Article
Engineering, Environmental
Sonia Kacprzak et al.
Summary: This study investigates the presence, sources, types, levels, and impacts of microplastics in indoor air. The results reveal the scale and complexity of airborne microplastics pollution, as well as technological deficiencies in testing methods. Possible methods of controlling and reducing these pollutants are also explored.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
News Item
Multidisciplinary Sciences
XiaoZhi Lim
Summary: Scientists are urgently studying the tiny plastic specks found in marine animals and in humans.
Article
Pharmacology & Pharmacy
Oveis Pourmehran et al.
Summary: Acoustic drug delivery is an innovative method that can significantly improve the efficiency of drug delivery to the maxillary sinus. Research shows that using acoustic waves under specific conditions can greatly enhance the delivery of drugs to the sinuses.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Engineering, Environmental
Luis Fernando Amato-Lourenco et al.
Summary: This study confirmed the presence of microplastics in human lung tissues, with polyethylene and polypropylene being the most frequently detected polymers. The potential adverse effects of these microplastics on the respiratory system following inhalation are still unknown, but further research is needed to understand the heterogeneous characteristics of these contaminants.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Mechanics
Mohammad S. Islam et al.
Summary: The recent outbreak of COVID-19 has caused significant respiratory health issues globally, with a higher impact on the elderly. Research shows that as age increases, airway diameter decreases, and understanding SARS aerosol transmission in older adults can improve targeted aerosol drug delivery systems.
Article
Environmental Sciences
Mohammad S. Islam et al.
Summary: This study aimed to analyze airflow and aerosol transport in the age-specific lung, utilizing ANSYS Fluent solver and Large-Eddy Simulation (LES) model for numerical simulation. The results showed that airway size-reduction significantly affected airflow and particle transport in the upper airways. Higher deposition was reported at the mouth-throat region for larger diameter particles, and overall deposition efficiency increased with airway size reduction and flow rate.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Review
Pharmacology & Pharmacy
Kaveh Ahookhosh et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Pharmacology & Pharmacy
Oveis Pourmehran et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Computer Science, Interdisciplinary Applications
Hamidreza Mortazavy Beni et al.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2019)
Review
Environmental Sciences
Messika Revel et al.
CURRENT OPINION IN ENVIRONMENTAL SCIENCE & HEALTH
(2018)
Article
Engineering, Chemical
Mohammad S. Islam et al.
JOURNAL OF AEROSOL SCIENCE
(2017)
Article
Computer Science, Interdisciplinary Applications
Kiao Inthavong et al.
COMPUTERS & FLUIDS
(2011)
Article
Engineering, Chemical
Jinxiang Xi et al.
AEROSOL SCIENCE AND TECHNOLOGY
(2009)
Article
Engineering, Biomedical
Baoshun Ma et al.
ANNALS OF BIOMEDICAL ENGINEERING
(2009)
Article
Biophysics
P. Worth Longest et al.
JOURNAL OF BIOMECHANICS
(2007)
