4.5 Article

Novel and replicated clinical and genetic risk factors for toxicity from high-dose methotrexate in pediatric acute lymphoblastic leukemia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Novel risk factors for glucarpidase use in pediatric acute lymphoblastic leukemia: Hispanic ethnicity, age, and the ABCC4 gene

Mark C. Zobeck et al.

Summary: This study found that Hispanic ethnicity and age are associated with the use of Carboxypeptidase G(2) (CPDG(2); glucarpidase) as a rescue drug. Additionally, the study provided evidence that inherited genetic variation is associated with the risk of requiring CPDG(2).

PEDIATRIC BLOOD & CANCER (2021)

Article Hematology

Risk prediction for delayed clearance of high-dose methotrexate in pediatric hematological malignancies by machine learning

Min Zhan et al.

Summary: This study aimed to establish a predictive model using machine learning to identify children with hematologic malignancy at high risk for delayed clearance of high-dose methotrexate (HD-MTX). Five and three variables were found to be statistically significant in univariable and multivariate analysis. The C5.0 decision tree combined with SMOTE using five variables showed the highest AUC value (0.807).

INTERNATIONAL JOURNAL OF HEMATOLOGY (2021)

Article Oncology

Population pharmacokinetics of methotrexate in Mexican pediatric patients with acute lymphoblastic leukemia

Susanna E. Medellin-Garibay et al.

CANCER CHEMOTHERAPY AND PHARMACOLOGY (2020)

Article Computer Science, Theory & Methods

Practical Bayesian model evaluation using leave-one-out cross-validation and WAIC

Aki Vehtari et al.

STATISTICS AND COMPUTING (2017)

Article Computer Science, Interdisciplinary Applications

brms: An R Package for Bayesian Multilevel Models Using Stan

Paul-Christian Buerkner

JOURNAL OF STATISTICAL SOFTWARE (2017)

Article Oncology

Evaluation of incidence and risk factors for high-dose methotrexate-induced nephrotoxicity

Tracy Wiczer et al.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2016)

Article Oncology

Preventing and Managing Toxicities of High-Dose Methotrexate

Scott C. Howard et al.

ONCOLOGIST (2016)

Article Hematology

Genome-wide study of methotrexate clearance replicates SLCO1B1

Laura B. Ramsey et al.

Editorial Material Pharmacology & Pharmacy

Pharmacogenomics Knowledge for Personalized Medicine

M. Whirl-Carrillo et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)

Article Biochemistry & Molecular Biology

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

Laura B. Ramsey et al.

GENOME RESEARCH (2012)

Article Biotechnology & Applied Microbiology

Polymorphisms in the methotrexate transport pathway

Elixabet Lopez-Lopez et al.

Pharmacogenetics and Genomics (2012)

Article Biotechnology & Applied Microbiology

PharmGKB summary: methotrexate pathway

Torben S. Mikkelsen et al.

PHARMACOGENETICS AND GENOMICS (2011)

Article Biotechnology & Applied Microbiology

SLC19A1 pharmacogenomics summary

Sook Wah Yee et al.

PHARMACOGENETICS AND GENOMICS (2010)

Article Genetics & Heredity

A genomewide admixture mapping panel for hispanic/latino populations

Xianyun Mao et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Oncology

Understanding and managing methotrexate nephrotoxicity

Brigitte C. Widemann et al.

ONCOLOGIST (2006)

Article Pharmacology & Pharmacy

Population pharmacokinetics of high-dose methotrexate in children with acute lymphoblastic leukaemia

Dolores Aumente et al.

CLINICAL PHARMACOKINETICS (2006)

Article Medicine, General & Internal

Survival variability by race and ethnicity in childhood acute lymphoblastic leukemia

NS Kadan-Lottick et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)