☆ 4.6 Article

Qiqilian ameliorates vascular endothelial dysfunction by inhibiting NLRP3-ASC inflammasome activation in vivo and in vitro

PHARMACEUTICAL BIOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Materials Science, Biomaterials

A high-dosage microneedle for programmable lidocaine delivery and enhanced local long-lasting analgesia

Ze Qiang Zhao et al.

Summary: Considering the global prevalence of local pain, this study developed a GelMA MNs system for sustained delivery of lidocaine hydrochloride. Results showed that the system was reliable and efficient, enhancing and prolonging the anesthetic effect in a rat model. Biosafety evaluation confirmed the absence of side effects.

BIOMATERIALS ADVANCES (2022)

添加到收藏夹

Article Medicine, Research & Experimental

Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses

Nur Banu Bal et al.

Summary: This study compared the effects of resveratrol supplementation and regular exercise on hypertension-induced cellular stress responses of the myocardium. The results showed that both resveratrol and exercise reduced systolic blood pressure in hypertensive rats, improved cardiac muscle responses, and reduced oxidative stress. Regular exercise restored endoplasmic reticulum stress and decreased mitogenic activation, while resveratrol only improved mitophagy. Additionally, both resveratrol and exercise suppressed inflammation.

LIFE SCIENCES (2022)

添加到收藏夹

Article Cell Biology

Astragaloside IV attenuates inflammatory response mediated by NLRP-3/calpain-1 is involved in the development of pulmonary hypertension

Yang Sun et al.

Summary: The study found that AS-IV could inhibit monocrotaline-induced pulmonary arterial hypertension via the NLRP-3/calpain-1 pathway.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

添加到收藏夹

Article Engineering, Biomedical

Construction of pH-Dependent Nanozymes with Oxygen Vacancies as the High-Efficient Reactive Oxygen Species Scavenger for Oral-Administrated Anti-Inflammatory Therapy

Ning Zhao et al.

Summary: The study introduces a novel nanozyme NiCo2O4@PVP with good biocompatibility and reactive oxygen species (ROS) scavenging ability for treating inflammatory bowel disease (IBD). NiCo2O4@PVP can pass through the digestive tract and target the inflamed site for oral-administrated anti-inflammatory therapy, resulting in a significant decrease in the expression levels of inflammatory factors in the colon.

ADVANCED HEALTHCARE MATERIALS (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Autophagy contributes to angiotensin II induced dysfunction of HUVECs

Di Liu et al.

Summary: This study demonstrates that Ang II stimulation can increase autophagy levels in HUVECs, and activation of autophagy contributes to the dysfunction of HUVECs induced by Ang II.

CLINICAL AND EXPERIMENTAL HYPERTENSION (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Traditional Herbal Medicine Discovery for the Treatment and Prevention of Pulmonary Arterial Hypertension

Zhifeng Xue et al.

Summary: Pulmonary arterial hypertension (PAH) is a serious and fatal pulmonary disease characterized by pulmonary artery remodeling. Traditional herbal medicine (THM) treatment has been gradually showing advantages worldwide in treating PAH through multi-level and multi-target approaches, with potential mechanisms including suppression of cell proliferation and apoptosis, control of inflammation and oxidative stress, and regulation of vasoconstriction and ion channels. Clinical trials are ongoing for promising medicines like sodium tanshinone IIA sulfonate sodium and tetramethylpyrazine, and reverse pharmacology has been proposed for PAH treatment research and development.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Article Food Science & Technology

Quercetin Attenuates Atherosclerotic Inflammation by Inhibiting Galectin-3-NLRP3 Signaling Pathway

Hongxia Li et al.

Summary: This study investigates the anti-atherosclerotic properties of quercetin by modulating the Gal-3-NLRP3 pathway, showing promising effects in reducing atherosclerotic lesions. The findings suggest a potential strategy for the prevention and treatment of atherosclerosis using naturally-occurring quercetin.

MOLECULAR NUTRITION & FOOD RESEARCH (2021)

添加到收藏夹

Article Medicine, General & Internal

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

Bin Zhou et al.

Summary: Global prevalence of hypertension doubled from 1990 to 2019, with significant improvements in detection, treatment, and control rates. In 2019, 59% of women and 49% of men with hypertension were previously diagnosed, while treatment rates were 47% for women and 38% for men, with control rates at 23% for women and 18% for men. Disparities exist across countries, with some middle-income nations now outperforming high-income countries in hypertension management.

LANCET (2021)

添加到收藏夹

Article Pharmacology & Pharmacy

Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs

Rong Hu et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2020)

添加到收藏夹

Article Cell Biology

Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging

Ruiyun Wang et al.

AGING-US (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Ma Xing Shi Gan Decoction Attenuates PM2.5 Induced Lung Injury via Inhibiting HMGB1/TLR4/NFκB Signal Pathway in Rat

Yu-xiang Fei et al.

FRONTIERS IN PHARMACOLOGY (2019)

添加到收藏夹

Article Cell Biology

Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence

Chunhui Sun et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2019)

添加到收藏夹

Review Immunology

NLRP3: A Novel Mediator in Cardiovascular Disease

Wenyi Zhou et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

The role of mitochondria in NLRP3 inflammasome activation

Qiuyun Liu et al.

MOLECULAR IMMUNOLOGY (2018)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Role of NLRP3 inflammasome in the pathogenesis of cardiovascular diseases

Dongling Liu et al.

BASIC RESEARCH IN CARDIOLOGY (2018)

添加到收藏夹

Article Peripheral Vascular Disease

Recent Advances in Angiotensin Research

Katrina M. Mirabito Colafella et al.

HYPERTENSION (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells

Fang Bian et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Traditional Chinese Medicine for Cardiovascular Disease Evidence and Potential Mechanisms

Panpan Hao et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

添加到收藏夹

Article Cell Biology

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

Hai-Jian Sun et al.

CELL DEATH & DISEASE (2017)

添加到收藏夹

Review Cell Biology

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

Lulu Li et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2015)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Ellagic acid prevents monocrotaline-induced pulmonary artery hypertension via inhibiting NLRP3 inflammasome activation in rats

Bing Tang et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

添加到收藏夹

Correction Cardiac & Cardiovascular Systems

Traditional Chinese medication for cardiovascular disease (vol 12, pg 115, 2015)

Pan-Pan Hao et al.

NATURE REVIEWS CARDIOLOGY (2015)

添加到收藏夹

Review Cell Biology

Autophagy as a pro-death pathway

Donna Denton et al.

IMMUNOLOGY AND CELL BIOLOGY (2015)

添加到收藏夹

Review Endocrinology & Metabolism

Autophagy-a key player in cellular and body metabolism

Kook Hwan Kim et al.

NATURE REVIEWS ENDOCRINOLOGY (2014)

添加到收藏夹

Article Cardiac & Cardiovascular Systems

Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation

Lu Long et al.

CIRCULATION RESEARCH (2013)

添加到收藏夹

Review Immunology

Autophagy in infection, inflammation and immunity

Vojo Deretic et al.

NATURE REVIEWS IMMUNOLOGY (2013)

添加到收藏夹

Review Physiology

Contribution of oxidative stress to endothelial dysfunction in hypertension

Bruno R. Silva et al.

FRONTIERS IN PHYSIOLOGY (2012)

添加到收藏夹

Article Multidisciplinary Sciences

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou et al.

NATURE (2011)

添加到收藏夹

Article Peripheral Vascular Disease

Vascular Endothelial Function and Hypertension: Insights and Directions

Kodlipet Dharmashankar et al.

CURRENT HYPERTENSION REPORTS (2010)

添加到收藏夹

Review Physiology

Endothelial dysfunction and vascular disease

P. M. Vanhoutte et al.

ACTA PHYSIOLOGICA (2009)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.