4.7 Review

Hidradenitis Suppurativa in Pediatric Patients

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Dermatology

Hidradenitis suppurativa in pediatric patients

Ellie Choi et al.

Summary: Interest and research in hidradenitis suppurativa (HS) have grown in the past decade, expanding knowledge about associated comorbidities and treatment efficacy. Limited understanding exists about pediatric-onset HS, but with increasing prevalence of childhood obesity and awareness of HS, physicians may encounter younger HS patients more frequently.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Article Dermatology

Comorbidity screening in hidradenitis suppurativa: Evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations

Amit Garg et al.

Summary: This study aims to provide evidence-based screening recommendations for comorbidities associated with HS. Screening recommendations were made based on the consistency and quality of existing studies, disease prevalence and magnitude of association, as well as benefits, harms, and feasibility of screening. A total of 30 comorbidities were recommended for screening in order to improve patients' quality of life and health status.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Article Dermatology

Pediatric Hidradenitis Suppurativa: A Cross-Sectional Study on Clinical Features and Treatment Approaches

Simone Garcovich et al.

Summary: Pediatric hidradenitis suppurativa presents a clinical spectrum comparable to adult-onset disease, with key risk factors being patient's age and BMI. Compared to the general hidradenitis suppurativa population, adolescent patients are more likely to exhibit obesity and smoking as risk factors.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2022)

Review Dermatology

Biologic Use in Pediatric Patients With Hidradenitis Suppurativa: A Systematic Review

Muskaan Sachdeva et al.

Summary: This study analyzed the outcomes of biologic therapy in 26 pediatric patients with HS, finding that anti-TNF alpha inhibitors were the most commonly used biologics. Approximately 73% of patients experienced partial resolution, around 23% had complete resolution, and no adverse events were reported.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2022)

Letter Dermatology

Wound dressings improve quality of life for hidradenitis suppurativa patients

Caralin Schneider et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Letter Dermatology

Trends in the prescribing pattern of spironolactone for acne and hidradenitis suppurativa in adolescents

Mikael Horissian et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Article Dermatology

Racial and ethnic health disparities in dermatology in the United States. Part 2: Disease-specific epidemiology, characteristics, management, and outcomes

Kimberly Shao et al.

Summary: Racial and ethnic disparities in dermatology have a negative impact on outcomes, such as mortality and quality of life. Dermatologists and dermatologic surgeons need to be aware of disease-specific inequities that may affect their practice. This article reviews the gaps in frequency, clinical presentation, management, and outcomes by race and ethnicity for various cutaneous malignancies and inflammatory disorders.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Article Dermatology

Surgical deroofing in pediatric patients with hidradenitis suppurativa

Maria Leszczynska et al.

Summary: Hidradenitis suppurativa is a chronic inflammatory follicular disorder, and deroofing is an important adjunct therapy for pediatric patients with moderate-to-severe HS.

PEDIATRIC DERMATOLOGY (2022)

Article Dermatology

Drug Survival of Biologics in Patients With Hidradenitis Suppurativa

Hans Christian Ring et al.

Summary: In this cohort study, drug survival was comparable between adalimumab, infliximab, and ustekinumab but significantly lower for etanercept. There were no differences in drug survival among biologic-naive and nonnaive patients.

JAMA DERMATOLOGY (2022)

Review Biochemistry & Molecular Biology

Paradoxical Hidradenitis Suppurativa during Biologic Therapy, an Emerging Challenge: A Systematic Review

Angelo Ruggiero et al.

Summary: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with unclear pathogenesis. Recent research has improved our understanding of the mechanisms behind HS lesions, including follicular occlusion and rupture, immune response activation, and imbalanced cytokine production. Paradoxical HS occurrences have been increasingly reported during treatment with biologic drugs.

BIOMEDICINES (2022)

Article Dermatology

An Anti-Interleukin-17A Monoclonal Antibody, Ixekizumab, in the Treatment of Resistant Hidradenitis Suppurativa: A Case Series

Pelin Esme et al.

Summary: Ixekizumab may be an effective treatment option for challenging cases of hidradenitis suppurativa, leading to improvement in symptoms within a short period of time.

SKIN APPENDAGE DISORDERS (2022)

Article Dermatology

Antiandrogen therapy in hidradenitis suppurativa: finasteride for females

K. M. Babbush et al.

Summary: The study suggests that finasteride is a safe and effective alternative for female patients with HS who have contraindications or intolerance to spironolactone. Most patients reported satisfaction with finasteride and willingness to continue therapy.

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2022)

Review Dermatology

Intralesional Treatments in Hidradenitis Suppurativa: A Systematic Review

Carlos Cuenca-Barrales et al.

Summary: This study aimed to synthesize the available scientific evidence on intralesional (IL) treatments in hidradenitis suppurativa (HS). The results showed that corticosteroid injections and light-based therapies appear to be effective and safe for both acute inflammatory lesions and fistulas. However, more prospective studies with larger sample sizes and standardized outcomes are needed to provide further scientific evidence on the subject.

DERMATOLOGY (2022)

Letter Dermatology

Pediatric hidradenitis suppurativa: epidemiology, disease presentation, and treatments

Justine Seivright et al.

JOURNAL OF DERMATOLOGICAL TREATMENT (2022)

Letter Dermatology

A report of 1290 pediatric hidradenitis suppurativa hospitalizations: A nationwide analysis from the Kids' Inpatient Database

Ehizogie Edigin et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2022)

Article Dermatology

Severe recalcitrant hidradenitis suppurativa in a 2-year-old boy with partial trisomy 13

Emily Keyes et al.

Summary: This is a case report of a 2-year-old boy with mosaic trisomy 13 and immunodeficiency who developed severe hidradenitis suppurativa at the age of 18 months. Unresponsive to standard therapies, he showed partial improvement after immunoglobulin replacement therapy.

PEDIATRIC DERMATOLOGY (2022)

Article Dermatology

A cross-sectional study of pediatric hidradenitis suppurativa and the value of the International Hidradenitis Suppurativa Severity Score System (IHS4) as a pediatric clinical trial inclusion criteria

Helen Bui et al.

Summary: This study analyzed the characteristics of pediatric Hidradenitis suppurativa (HS) patients and the eligibility criteria in adult trials, providing reference for future pediatric HS studies. The study found that pediatric patients had fewer abscesses and inflammatory nodules, with the majority being Hurley stage I or II. The commonly used criteria in adult trials may severely limit the recruitment of pediatric patients.

PEDIATRIC DERMATOLOGY (2022)

Article Dermatology

Evaluation of Hidradenitis Suppurativa Diagnostic Criteria in Pediatric Patients

Nicole W. Kittler et al.

Summary: This retrospective study examined the diagnosis of pediatric patients with HS. The results showed that approximately 40% of the 297 adolescent HS patients did not meet all major diagnostic criteria at the time of diagnosis, largely due to failure to fulfill the 6-month recurrence interval criterion.

JAMA DERMATOLOGY (2022)

Review Health Care Sciences & Services

Disease-Specific Health Disparities: A Targeted Review Focusing on Race and Ethnicity

Mark R. Cullen et al.

Summary: This study summarizes the recent evidence of racial and ethnic disparities in various diseases in the United States, aiming to provide information for clinicians and health equity research.

HEALTHCARE (2022)

Article Dermatology

Isotretinoin in the treatment of hidradenitis suppurativa: a retrospective study

Nirali Patel et al.

Summary: Having a history of pilonidal cyst is associated with a beneficial response to isotretinoin in HS patients.

JOURNAL OF DERMATOLOGICAL TREATMENT (2021)

Article Dermatology

PASH, PAPASH, PsAPASH, and PASS: The autoinflammatory syndromes of hidradenitis suppurativa

Simone Garcovich et al.

Summary: Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving skin folds, with complex pathogenesis and diverse clinical manifestations. Syndromic HS patients have severe disease, systemic inflammation, and resistance to conventional treatments. Treatment should be personalized, and classification criteria are constantly evolving.

CLINICS IN DERMATOLOGY (2021)

Letter Dermatology

Quality of life in hidradenitis suppurativa: A cross-sectional study of a pediatric population

Rachel McAndrew et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

Article Dermatology

Prevalence of inflammatory bowel disease among pediatric patients with hidradenitis suppurativa and the potential role of screening with fecal calprotectin

Allison M. Lloyd-McLennan et al.

Summary: Previous studies have shown an increased prevalence of inflammatory bowel disease in adults with hidradenitis suppurativa (HS). This study found that pediatric patients with HS may also have a higher prevalence of IBD, suggesting more widespread screening may be necessary. While fecal calprotectin (FC) is not commonly used in this population, it may be a useful tool for screening for IBD.

PEDIATRIC DERMATOLOGY (2021)

Article Dermatology

Treatment of hidradenitis suppurativa with tetracycline, doxycycline, or lymecycline: a prospective study

Astrid-Helene Ravn Jorgensen et al.

Summary: Oral treatment with tetracycline, doxycycline, and lymecycline is effective and safe for patients with hidradenitis suppurativa (HS), with tetracycline showing the greatest clinical improvement as measured by the Hidradenitis Suppurativa Score (HSS). Higher reduction in HSS is associated with lower BMI, Hurley stage III, higher HSS at baseline, and higher number of boils in the preceding month at baseline after multivariate adjustment.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2021)

Article Allergy

Epithelialized tunnels are a source of inflammation in hidradenitis suppurativa

Kristina Navrazhina et al.

Summary: The study found that tunnels in hidradenitis suppurativa (HS) play an immunologically active role in disease activity, showing inflammation characteristics and associated with increased infiltration of T cells, dendritic cells, and neutrophils. Treatment with medication reduced the size and draining of tunnels, indicating their involvement in disease inflammation.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Article Dermatology

The link between hidradenitis suppurativa and phylloid hypomelanosis in partial trisomy-13 mosaicism: New evidences and further genetic/pathogenetic insights

Riccardo Forconi et al.

Summary: Partial trisomy-13 mosaicism (PT13M) can lead to phylloid hypomelanosis (PH) and may be related to follicular occlusion genes.

PEDIATRIC DERMATOLOGY (2021)

Article Dermatology

Hidradenitis Suppurativa in the Pediatric Population An International, Multicenter, Retrospective, Cross-sectional Study of 481 Pediatric Patients

Carmen Liy-Wong et al.

Summary: The study highlighted a gap in recognizing and diagnosing pediatric HS, with pediatric patients likely to present with other comorbidities. More prospective observational and interventional studies are needed to better understand the clinical course and optimal treatments for pediatric HS.

JAMA DERMATOLOGY (2021)

Article Obstetrics & Gynecology

Care for Adolescents With Polycystic Ovary Syndrome: Development and Prescribing Patterns of a Multidisciplinary Clinic

C. Torres-Zegarra et al.

Summary: A multidisciplinary clinic was established to provide comprehensive care to adolescent girls with PCOS, revealing common co-morbidities in metabolic, dermatologic, and psychological aspects. Commonly prescribed therapies included topical acne preparations, estrogen-containing hormonal therapy, and metformin.

JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY (2021)

Review Dermatology

Vaccines: Considerations for pediatric dermatology patients on immunosuppressive agents

Mumtaz A. Munshi et al.

Summary: Pediatric dermatologists should be aware of immunization schedules and special recommendations for patients on immunosuppressive agents to prevent vaccine-preventable infections. Before starting immunosuppressive therapy, it is important to review vaccine history and administer necessary age-appropriate or catch-up vaccines, with live vaccines generally contraindicated and inactivated vaccines safe to administer during therapy.

PEDIATRIC DERMATOLOGY (2021)

Article Dermatology

Differences Between Children and Adults With Hidradenitis Suppurativa

Katherine K. Hallock et al.

Summary: This retrospective cohort study compared the clinical characteristics and health care utilization patterns of pediatric vs adult patients with HS. The study found that pediatric patients with HS tend to utilize high-cost emergency department (ED) care, while adult patients are more likely to have inpatient stays. The data suggest opportunities to improve recognition of HS in pediatric patients by nondermatologists and dermatologists.

JAMA DERMATOLOGY (2021)

Article Dermatology

KID Syndrome and Hidradenitis Suppurativa: A Rare Association Responding to Surgical Treatment

Vincenzo Bettoli et al.

Summary: The association between KID syndrome and HS is rare, with surgical intervention achieving excellent results in the difficult management of this condition. Despite technical challenges, surgery is strongly recommended for these patients due to its effectiveness.

SKIN APPENDAGE DISORDERS (2021)

Article Dermatology

Hidradenitis suppurativa in a cohort of overweight and obese children and adolescents

Pernille Lindso Andersen et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2020)

Article Dermatology

Epidemiology, clinical presentation, and pathogenesis

Samantha R. Goldburg et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

Article Dermatology

Follicular occlusion disorders in Down syndrome patients

Maya Firsowicz et al.

PEDIATRIC DERMATOLOGY (2020)

Letter Dermatology

Secukinumab in the treatment of moderate to severe hidradenitis suppurativa: Results of an open-label trial

Rachel G. Casseres et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

Article Dermatology

Weight counseling in pediatric hidradenitis suppurativa patients

Barbara Reichert et al.

PEDIATRIC DERMATOLOGY (2020)

Letter Dermatology

Dapsone therapy for hidradenitis suppurativa

G. Murray et al.

BRITISH JOURNAL OF DERMATOLOGY (2020)

Article Dermatology

New-onset depression among children, adolescents, and adults with hidradenitis suppurativa

Shari Wright et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

Review Dermatology

Hidradenitis suppurativa in paediatric patients: a retrospective monocentric study in Germany and review of the literature

A. G. Vaiopoulos et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2020)

Article Medicine, General & Internal

Hidradenitis suppurativa

Robert Sabat et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Review Dermatology

Dermatologic conditions in Down syndrome: A single-center retrospective chart review

Jillian F. Rork et al.

PEDIATRIC DERMATOLOGY (2020)

Review Dermatology

What causes hidradenitis suppurativa ?-15 years after

Christos C. Zouboulis et al.

EXPERIMENTAL DERMATOLOGY (2020)

Article Dermatology

Metformin as Adjunctive Therapy for Pediatric Patients With Hidradenitis Suppurativa

Christine Moussa et al.

JOURNAL OF DRUGS IN DERMATOLOGY (2020)

Letter Dermatology

Systemic Steroids in the Management of Moderate-to-severe Hidradenitis Suppurativa

B. Duarte et al.

ACTAS DERMO-SIFILIOGRAFICAS (2020)

Letter Dermatology

Distribution of Self-reported Hidradenitis Suppurativa Age at Onset

Haley B. Naik et al.

JAMA DERMATOLOGY (2019)

Review Dermatology

Combination Therapies for Hidradenitis Suppurativa: A Retrospective Chart Review of 31 Patients

Meghan L. McPhie et al.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2019)

Article Dermatology

Ertapenem - a potent treatment for clinical and quality of life improvement in patients with hidradenitis suppurativa

Taylor L. Braunberger et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2018)

Article Dermatology

Somatic and psychiatric comorbidities of hidradenitis suppurativa in children and adolescents

Hannu Tiri et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2018)

Article Dermatology

Hidradenitis suppurativa in children: The Henry Ford experience

Taylor L. Braunberger et al.

PEDIATRIC DERMATOLOGY (2018)

Article Dermatology

Hidradenitis Suppurativa: An Asian Perspective from a Singaporean Institute

Ellie Choi et al.

SKIN APPENDAGE DISORDERS (2018)

Review Medicine, General & Internal

Hidradenitis Suppurativa Advances in Diagnosis and Treatment

Ditte Marie Lindhardt Saunte et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Review Dermatology

Recognizing syndromic hidradenitis suppurativa: a review of the literature

J. Gasparic et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2017)

Article Dermatology

Hidradenitis Suppurativa in Children Treated with Finasteride-A Case Series

Fernando Mota et al.

PEDIATRIC DERMATOLOGY (2017)

Article Genetics & Heredity

Acne conglobata in a long-term survivor with trisomy 13, accompanied by selective IgM deficiency

Chiyoko N. Inoue et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2017)

Article Dermatology

Cyclosporine treatment of severe Hidradenitis suppurativa - A case series

Marianne D. Anderson et al.

JOURNAL OF DERMATOLOGICAL TREATMENT (2016)

Article Dermatology

Endocrinologic Aspects of Hidradenitis Suppurativa

Loannis Karagiannidis et al.

DERMATOLOGIC CLINICS (2016)

Article Dermatology

The Genetics of Hidradenitis Suppurativa

John R. Ingram

DERMATOLOGIC CLINICS (2016)

Article Dermatology

Intralesional triamcinolone for flares of hidradenitis suppurativa (HS): A case series

Peter Theut Riis et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2016)

Article Medicine, General & Internal

Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa

Alexa B. Kimball et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Dermatology

A case series of 20 women with hidradenitis suppurativa treated with spironolactone

Andrew Lee et al.

AUSTRALASIAN JOURNAL OF DERMATOLOGY (2015)

Letter Dermatology

Hidradenitis suppurativa-acne inversa: a relevant dermatosis in paediatric patients

V. Bettoli et al.

BRITISH JOURNAL OF DERMATOLOGY (2015)

Article Dermatology

Hidradenitis suppurativa in prepubescent and pubescent children

Noah Scheinfeld

CLINICS IN DERMATOLOGY (2015)

Editorial Material Gastroenterology & Hepatology

Hidradenitis Suppurativa and Pediatric Crohn Disease

Balaji Natarajan et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2015)

Article Dermatology

Hidradenitis suppurativa in the pediatric population

Carmen Liy-Wong et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2015)

Article Dermatology

Correlation of early-onset hidradenitis suppurativa with stronger genetic susceptibility and more widespread involvement

Inge E. Deckers et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2015)

Article Dermatology

Psychiatric comorbidities in 3207 patients with hidradenitis suppurativa

E. Shavit et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2015)

Article Immunology

Bacterial Pathogens Associated with Hidradenitis Suppurativa, France

Helene Guet-Revillet et al.

EMERGING INFECTIOUS DISEASES (2014)

Article

Treatment of Hidradenitis Suppurativa With Etanercept Injection

David R. Adams et al.

ARCHIVES OF DERMATOLOGY (2010)

Article Dermatology

EXTENSIVE COMEDONAL AND CYSTIC ACNE IN PATAU SYNDROME

Antonio Torrelo et al.

PEDIATRIC DERMATOLOGY (2010)

Article

Phylloid Hypomelanosis and Mosaic Partial Trisomy 13

M. Antonia González-Enseñat et al.

ARCHIVES OF DERMATOLOGY (2009)

Article Dermatology

A prospective clinical trial of open-label etanercept for the treatment of hidradenitis suppurativa

Robert A. Lee et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2009)

Article Dermatology

Early-onset hidradenitis suppurativa

RA Palmer et al.

CLINICAL AND EXPERIMENTAL DERMATOLOGY (2001)

Article Dermatology

The clinical genetics of hidradenitis suppurativa revisited

JM Von der Werth et al.

BRITISH JOURNAL OF DERMATOLOGY (2000)