☆ 4.6 Article

Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract

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Probabilistic pharmacokinetic modeling of airborne lead corresponding to toxicologically relevant blood lead levels in workers

Lisa M. Sweeney

Summary: The Department of Defense commissioned the National Research Council to assess the health effects of DOD personnel exposed to lead at firing ranges. The report concluded that current exposure limits and blood lead levels were not adequately protective. The relationship between airborne lead levels and blood lead levels is of interest to the DOD for future exposure limit selection.

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NEUROTOXICOLOGY (2017)

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Article Toxicology

Application of a Multi-Route Physiologically Based Pharmacokinetic Model for Manganese to Evaluate Dose-Dependent Neurological Effects in Monkeys

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Article Pharmacology & Pharmacy

Influence of particle solubility on the delivery of inhaled manganese to the rat brain: Manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure

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Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract

相关参考文献

Probabilistic pharmacokinetic modeling of airborne lead corresponding to toxicologically relevant blood lead levels in workers

In vivo effects: Methodologies and biokinetics of inhaled nanomaterials

The application of PBPK models in estimating human brain tissue manganese concentrations

Application of a Multi-Route Physiologically Based Pharmacokinetic Model for Manganese to Evaluate Dose-Dependent Neurological Effects in Monkeys

Evaluating transport of manganese from olfactory mucosa to striatum by pharmacokinetic modeling

Influence of particle solubility on the delivery of inhaled manganese to the rat brain: Manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure

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