Thio(seleno)cyano-difluoroalkylation of Alkenes Using Visible-Light Photocatalysis

A mild and efficient three-component thio(seleno)cyano-difluoroalkylation of simple alkenes is demonstrated using an iridium(ruthenium) photocatalyst. This protocol provides a direct and regioselective installation of both C-S(Se)CN [thio(seleno)cyanation] and C-CF (difluoroalkylation) bonds.

Automated summary

This study demonstrates a mild and efficient three-component thio(seleno)cyano-difluoroalkylation of simple alkenes using an iridium(ruthenium) photocatalyst, which provides a direct and regioselective installation of both C-S(Se)CN and C-CF bonds.