4.8 Article

Lewis-Acid-Catalyzed Reductive Hydroalkoxylation of Propargylic N-Hydroxylamines Gives Stereoselective Access to Isoxazolidines

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Investigations to mechanism and applications of the glycosylation protocol employing 8-methyltosylaminoethynyl-1-naphthyl (MTEAN) glycoside donors

Si-Yu Zhou et al.

Summary: Based on the efficient glycosylation capability of silyl ethers, the new MTEAN glycosylation protocol was extended to nucleoside synthesis, late-stage modification of bioactive molecules, and stereoselective construction of 1,2-cis-glucosidic linkages using silyl ethers of the acceptors. The mechanism of the reaction was investigated and determined to be a TfOH-catalyzed ynamide functionality-initiated process.

JOURNAL OF CARBOHYDRATE CHEMISTRY (2022)

Article Chemistry, Organic

Leveraging Alkyne-Oximium Cyclization for the Stereoselective Synthesis of Isoxazolidine

Santosh J. Gharpure et al.

Summary: A highly diastereoselective synthesis of isoxazolidine with three contiguous stereocenters mediated by TMSOTf is described. O-propargyl hydroxylamines are utilized as a novel building block for the rapid assembly of isoxazolidines via alkyne-oximium cyclization. The strategy can be used in the synthesis of enantiomerically enriched isoxazolidines, and reductive cleavage of the N-O bond allows precise control over all formed stereocenters.

ORGANIC LETTERS (2022)

Article Chemistry, Organic

Synthesis of the sedum and related alkaloids: A personal perspective

Roderick W. Bates

TETRAHEDRON LETTERS (2018)

Review Chemistry, Multidisciplinary

Isoxazolidine: A Privileged Scaffold for Organic and Medicinal Chemistry

Matheo Berthet et al.

CHEMICAL REVIEWS (2016)

Review Chemistry, Organic

Isoxazolidines as Biologically Active Compounds

M. A. Chiacchio et al.

CURRENT ORGANIC SYNTHESIS (2016)

Article Chemistry, Organic

Synthesis of 4-Isoxazolines through Gold(I)-Catalyzed Cyclization of Propargylic N-Hydroxylamines

B. Chandrasekhar et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Synthesis and Biological Properties of 5-(1H-1,2,3-Triazol-4-yl)isoxazolidines: A New Class of C-Nucleosides

Salvatore V. Giofre et al.

MOLECULES (2015)

Article Multidisciplinary Sciences

Activity of the novel fungicide SYP-Z048 against plant pathogens

Fengping Chen et al.

SCIENTIFIC REPORTS (2014)

Article Biochemistry & Molecular Biology

Synthesis and biological evaluation of 3-hydroxymethyl-5-(1H-1,2,3-triazol) isoxazolidines

Roberto Romeo et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2013)

Article Chemistry, Organic

TMSOTf-Catalyzed Silylation: Streamlined Regioselective One-Pot Protection and Acetylation of Carbohydrates

A. Abragam Joseph et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2012)

Article Chemistry, Medicinal

Enhancement in antimicrobial activity of 2-(phenyl)-3(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine

MP Sadashiva et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Biochemistry & Molecular Biology

Synthesis and microbial inhibition study of novel 5-imidazolyl substituted isoxazolidines

MP Sadashiva et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2004)

Article Chemistry, Medicinal

Synthesis of novel isoxazolidine derivatives and studies for their antifungal properties

KRR Kumar et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2003)