Golgi in and out: multifaceted role and journey of manganese

Manganese (Mn) is pivotal for plant growth and development but little is known about the processes that control its homeostasis in the cell. A spotlight on the pools of intracellular manganese and their cellular function has recently been gained through the characterization of new Mn transporters. In particular, transporters catalyzing the ins and outs of Mn at the various Golgi membranes have revealed the central role of the Golgi pool of Mn in the synthesis of the cell wall and as a reservoir for the numerous cellular Mn-dependent pathways whose calibration relies on a set of Golgi-resident transporters of the BICAT and NRAMP families.

Automated summary

Manganese (Mn) is crucial for plant growth and development, and recent studies have shed light on the processes controlling its homeostasis in the cell through the identification of new Mn transporters. These transporters, particularly those at the Golgi membranes, play a central role in regulating the synthesis of cell walls and the various Mn-dependent pathways. These findings have highlighted the importance of Golgi-resident transporters in maintaining cellular Mn levels.