☆ 4.8 Editorial Material

POSITIVE Results for Breast Cancer Survivors Who Desire Pregnancy

NEW ENGLAND JOURNAL OF MEDICINE (2023)

Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analysis of 7030 women from four randomised trials

R. Bradley et al.

Summary: Aromatase inhibitors are more effective than tamoxifen in reducing the risk of breast cancer recurrence in premenopausal women receiving ovarian suppression. The main benefit is observed in the first 4 years of treatment, with no additional benefit or loss of benefit in the following years up to 10.

LANCET ONCOLOGY (2022)

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Review Oncology

Pregnancy After Breast Cancer: A Systematic Review and Meta-Analysis

Matteo Lambertini et al.

Summary: This study found that breast cancer survivors are less likely to have a subsequent pregnancy compared to the general population, and they face higher risks during pregnancy, especially among those who have received chemotherapy. However, compared to breast cancer patients without subsequent pregnancy, those who become pregnant have better disease-free survival and overall survival rates.

JOURNAL OF CLINICAL ONCOLOGY (2021)

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Article Oncology