Emerging computational motifs: Lessons from the retina

The retinal neuronal circuit is the first stage of visual processing in the central nervous system. The efforts of scientists over the last few decades indicate that the retina is not merely an array of photosensitive cells, but also a processor that performs various computations. Within a thickness of only similar to 200 mu m, the retina consists of diverse forms of neuronal circuits, each of which encodes different visual features. Since the discovery of direction-selective cells by Horace Barlow and Richard Hill, the mechanisms that generate direction selectivity in the retina have remained a fascinating research topic. This review provides an overview of recent advances in our understanding of direction-selectivity circuits. Beyond the conventional wisdom of direction selectivity, emerging findings indicate that the retina utilizes complicated and sophisticated mechanisms in which excitatory and inhibitory pathways are involved in the efficient encoding of motion information. As will become evident, the discovery of computational motifs in the retina facilitates an understanding of how sensory systems establish feature selectivity.

Automated summary

The retinal neuronal circuit in the central nervous system is the first stage of visual processing. Recent advances in understanding direction-selectivity circuits have revealed that the retina utilizes complex mechanisms for encoding motion information. These discoveries of computational motifs in the retina contribute to our understanding of how sensory systems establish feature selectivity.