4.8 Article

Centrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing brain

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

A ?-tubulin complex-dependent pathway suppresses ciliogenesis by promoting cilia disassembly

Sahana Shankar et al.

Summary: This study reveals a y-tubulin ring complex (y-TuRC)-dependent pathway that promotes cilia disassembly and prevents cilia formation. It is further demonstrated that Kif2A is recruited to the cilium basal body in a y-TuRC-dependent manner. These findings illustrate the important role of y-TuRC in ciliogenesis.

CELL REPORTS (2022)

Article Multidisciplinary Sciences

Microtubule retrograde flow retains neuronal polarization in a fluctuating state

Max Schelski et al.

Summary: In developing vertebrate neurons, microtubules flow retrogradely within the neurites to the soma, inhibiting neurite growth. However, shortly after axon formation, microtubule retrograde flow slows down, enabling axon extension.

SCIENCE ADVANCES (2022)

Article Multidisciplinary Sciences

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity

Adam C. O'Neill et al.

Summary: The centrosome serves as an anchor for the cytoskeleton and plays a crucial role in cell division, migration, and cilia formation. By using spatial proteomics, researchers have uncovered protein interaction networks specific to the centrosome in human induced pluripotent stem cell-derived neural stem cells and neurons. These cell type-specific centrosome interactomes explain how genetic variants in widespread proteins can lead to brain-specific phenotypes.

SCIENCE (2022)

Article Cell Biology

Microtubule nucleation: The waltz between γ-tubulin ring complex and associated proteins

Peng Liu et al.

Summary: Microtubules, essential cytoskeletal elements assembled from ab-tubulin dimers, have their nucleation initiated by the gamma-TuRC complex. Recent cryoelectron microscopy studies and in vitro assays have revealed the molecular organization and potential activation mechanisms of gamma-TuRC, deepening our understanding of microtubule nucleation mechanisms.

CURRENT OPINION IN CELL BIOLOGY (2021)

Article Neurosciences

Neuronal migration and disorders - an update

Fiona Francis et al.

Summary: This review highlights the genes, proteins, and subcellular mechanisms influencing cortical neuronal migration, as well as the disrupted mechanisms in a variety of migration disorders. Recent research has shown the significant role of the microtubule cytoskeleton in migrating neurons, with variable impacts revealed in different cell compartments. In addition to microtubules, disruptions of actin cytoskeleton, extracellular matrix, adhesion molecules, and signaling pathways have also been identified as causative factors in cortical neuronal migration dysfunction.

CURRENT OPINION IN NEUROBIOLOGY (2021)

Article Biotechnology & Applied Microbiology

A novel TUBG1 mutation with neurodevelopmental disorder caused by malformations of cortical development

Ru Shen et al.

Summary: This study reported a case of a girl with developmental delay, psychomotor regression, epilepsy, and left external ear deformity. Through genetic data analysis, a novel TUBG1 mutation was identified as the potential cause of the neurodevelopmental disorders.

BIOMED RESEARCH INTERNATIONAL (2021)

Review Cell Biology

The Multifaceted Roles of Primary Cilia in the Development of the Cerebral Cortex

Kerstin Hasenpusch-Theil et al.

Summary: The formation of the cerebral cortex, a complex process involving various types of neurons and complex connections, is crucial for advanced neural functions. Recent studies have linked cilia to processes such as neurogenesis and neuronal migration during cortex development.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Review Neurosciences

Primary Cilia and Centrosomes in Neocortex Development

Michaela Wilsch-Braeuninger et al.

Summary: This article discusses the roles of neural stem and progenitor cells in neocortical development, with a specific focus on apical progenitor cells and centrosomes. The importance of the mode of progenitor cell divisions in ensuring the appropriate size and structure of the neocortex is emphasized.

FRONTIERS IN NEUROSCIENCE (2021)

Article Biochemistry & Molecular Biology

The gamma-tubulin ring complex: Deciphering the molecular organization and assembly mechanism of a major vertebrate microtubule nucleator

Anna Bohler et al.

Summary: Microtubules are protein cylinders with various functions in cells, and their dynamic architecture allows for growth and shrinkage. In higher eukaryotes, microtubule assembly is initiated by the gamma-tubulin ring complex, with recent breakthroughs in structural analysis and recombinant reconstitution providing new insights into its functioning.

BIOESSAYS (2021)

Article Neurosciences

RhoA drives actin compaction to restrict axon regeneration and astrocyte reactivity after CNS injury

Sina Stern et al.

Summary: Studies reveal that an inhibitory extracellular environment and neuron-intrinsic processes work together to prevent axon regeneration in the adult central nervous system. Genetic loss-of-function experiments show that the small GTPase RhoA relays extracellular inhibitory signals to the cytoskeleton. Neuronal RhoA restricts axon regeneration by activating myosin II, while astrocytic RhoA limits injury-induced astrogliosis through YAP signaling.

NEURON (2021)

Article Cell Biology

WDR47 protects neuronal microtubule minus ends from katanin-mediated severing

Robin R. Buijs et al.

Summary: Experimental evidence shows that the neuron-enriched protein WDR47 interacts with CAMSAPs, playing a critical role in axon and dendrite development. WDR47 accumulates at CAMSAP2-decorated microtubules, maintaining CAMSAP2 stretches and protecting minus ends from katanin-mediated severing.

CELL REPORTS (2021)

Review Cell Biology

The Golgi apparatus and cell polarity: Roles of the cytoskeleton, the Golgi matrix, and Golgi membranes

Yamini Ravichandran et al.

CURRENT OPINION IN CELL BIOLOGY (2020)

Article Multidisciplinary Sciences

Insights into the assembly and activation of the microtubule nucleator γ-TuRC

Peng Liu et al.

NATURE (2020)

Review Neurosciences

Molecular mechanisms of cell polarity in a range of model systems and in migrating neurons

Yves Jossin

MOLECULAR AND CELLULAR NEUROSCIENCE (2020)

Article Multidisciplinary Sciences

Primary cilium remodeling mediates a cell signaling switch in differentiating neurons

Gabriela Toro-Tapia et al.

SCIENCE ADVANCES (2020)

Article Biochemistry & Molecular Biology

Nesprin-2 Recruitment of BicD2 to the Nuclear Envelope Controls Dynein/Kinesin-Mediated Neuronal Migration In Vivo

Joao Carlos Goncalves et al.

CURRENT BIOLOGY (2020)

Article Multidisciplinary Sciences

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity

Zhengrong Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Primary cilium-dependent cAMP/PKA signaling at the centrosome regulates neuronal migration

Julie Stoufflet et al.

SCIENCE ADVANCES (2020)

Review Cell Biology

Non-Cell-Autonomous Mechanisms in Radial Projection Neuron Migration in the Developing Cerebral Cortex

Andi H. Hansen et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Biochemical Research Methods

Protocol for Evaluating Neuronal Polarity in Murine Models

Carlos Wilson et al.

STAR PROTOCOLS (2020)

Article Multidisciplinary Sciences

The centrosome protein AKNA regulates neurogenesis via microtubule organization

German Camargo Ortega et al.

NATURE (2019)

Article Genetics & Heredity

Case reports: novel TUBG1 mutations with milder neurodevelopmental presentations

Yue T. K. Yuen et al.

BMC MEDICAL GENETICS (2019)

Review Cell Biology

Neuronal Polarity: Positive and Negative Feedback Signals

Tetsuya Takano et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)

Article Biochemistry & Molecular Biology

RhoA Controls Axon Extension Independent of Specification in the Developing Brain

Sebastian Dupraz et al.

CURRENT BIOLOGY (2019)

Article Biochemistry & Molecular Biology

Radial somatic F-actin organization affects growth cone dynamics during early neuronal development

Durga Praveen Meka et al.

EMBO REPORTS (2019)

Article Biochemistry & Molecular Biology

Tubulinopathies continued: refining the phenotypic spectrum associated with variants in TUBG1

Stefanie Brock et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2018)

Article Biochemistry & Molecular Biology

The dual role of the centrosome in organizing the microtubule network in interphase

Maria P. Gavilan et al.

EMBO REPORTS (2018)

Article Multidisciplinary Sciences

CAMSAP3 maintains neuronal polarity through regulation of microtubule stability

Varisa Pongrakhananon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Neurosciences

The Development of Neuronal Polarity: A Retrospective View

Gary Banker

JOURNAL OF NEUROSCIENCE (2018)

Article Biochemical Research Methods

mScarlet: a bright monomeric red fluorescent protein for cellular imaging

Daphne S. Bindels et al.

NATURE METHODS (2017)

Article Neurosciences

Neuronal polarization: From spatiotemporal signaling to cytoskeletal dynamics

Max Schelski et al.

MOLECULAR AND CELLULAR NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

Reelin transiently promotes N-cadherin-dependent neuronal adhesion during mouse cortical development

Yuki Matsunaga et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Developmental Biology

Can injured adult CNS axons regenerate by recapitulating development?

Brett J. Hilton et al.

DEVELOPMENT (2017)

Article Cell Biology

Microtubule-organizing centers: from the centrosome to non-centrosomal sites

Ariana D. Sanchez et al.

CURRENT OPINION IN CELL BIOLOGY (2017)

Article Cell Biology

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

Jingchao Wu et al.

DEVELOPMENTAL CELL (2016)

Article Cell Biology

Divergent regulation of functionally distinct γ-tubulin complexes during differentiation

Andrew Muroyama et al.

JOURNAL OF CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

A mechanism for the elimination of the female gamete centrosome in Drosophila melanogaster

A. Pimenta-Marques et al.

SCIENCE (2016)

Review Biochemistry & Molecular Biology

Coordinating Neuronal Actin-Microtubule Dynamics

Charlotte H. Coles et al.

CURRENT BIOLOGY (2015)

Article Biochemical Research Methods

Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

Etsuo A. Susaki et al.

NATURE PROTOCOLS (2015)

Article Neurosciences

Cortical neurogenesis in the absence of centrioles

Ryan Insolera et al.

NATURE NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Binary recombinase systems for high-resolution conditional mutagenesis

Mario Hermann et al.

NUCLEIC ACIDS RESEARCH (2014)

Review Biology

Centrosomes as signalling centres

Christian Arquint et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

The centrosome-Golgi apparatus nexus

Rosa M. Rios

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Article Multidisciplinary Sciences

An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration

Roberta Azzarelli et al.

NATURE COMMUNICATIONS (2014)

Article Biochemical Research Methods

A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum

Nathan C. Shaner et al.

NATURE METHODS (2013)

Article Biochemistry & Molecular Biology

Microtubule dynamics in neuronal morphogenesis

Akira Sakakibara et al.

OPEN BIOLOGY (2013)

Article Biochemistry & Molecular Biology

N-cadherin specifies first asymmetry in developing neurons

Annette Gaertner et al.

EMBO JOURNAL (2012)

Article Biochemical Research Methods

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin et al.

NATURE METHODS (2012)

Article Multidisciplinary Sciences

γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis

Stanislav Vinopal et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules

Nobutoshi Tanaka et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Multidisciplinary Sciences

The Centrosome in Cells and Organisms

Michel Bornens

SCIENCE (2012)

Article Biochemistry & Molecular Biology

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics

Kathryn T. Applegate et al.

JOURNAL OF STRUCTURAL BIOLOGY (2011)

Article Multidisciplinary Sciences

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

Hideji Murakoshi et al.

NATURE (2011)

Article Developmental Biology

Microtubules are organized independently of the centrosome in Drosophila neurons

Michelle M. Nguyen et al.

NEURAL DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

Conserved Motif of CDK5RAP2 Mediates Its Localization to Centrosomes and the Golgi Complex

Zhe Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex

Yuk-Kwan Choi et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Neurosciences

Rac1 Regulates Neuronal Polarization through the WAVE Complex

Sabina Tahirovic et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Neurosciences

Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex

Froylan Calderon de Anda et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Multidisciplinary Sciences

A Direct Interaction with NEDD1 Regulates γ-Tubulin Recruitment to the Centrosome

Jantina A. Manning et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation

Michael Stiess et al.

SCIENCE (2010)

Review Neurosciences

Microtubule assembly, organization and dynamics in axons and dendrites

Cecilia Conde et al.

NATURE REVIEWS NEUROSCIENCE (2009)

Article Cell Biology

Microtubule stabilization specifies initial neuronal polarization

Harald Witte et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Biochemical Research Methods

Improving the photostability of bright monomeric orange and red fluorescent proteins

Nathan C. Shaner et al.

NATURE METHODS (2008)

Article Cell Biology

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion

Susanne Graser et al.

JOURNAL OF CELL SCIENCE (2007)

Article Neurosciences

Cdc42 regulates cofilin during the establishment of neuronal polarity

Boyan K. Garvalov et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Cell Biology

Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in dlg5-1- mice

Tamilla Nechiporuk et al.

DEVELOPMENTAL CELL (2007)

Article Biochemistry & Molecular Biology

LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons

Anthony P. Barnes et al.

Article Biochemistry & Molecular Biology

LKB1/STRAD promotes axon initiation during neuronal polarization

Maya Shelly et al.

Article Anatomy & Morphology

User-friendly semiautomated assembly of accurate image mosaics in microscopy

Philippe Thevenaz et al.

MICROSCOPY RESEARCH AND TECHNIQUE (2007)

Article Developmental Biology

Polarization and orientation of retinal ganglion cells in vivo

Flavio R. Zolessi et al.

NEURAL DEVELOPMENT (2006)

Article Biochemistry & Molecular Biology

Flies without centrioles

Renata Basto et al.

Article Biochemical Research Methods

Culturing hippocampal neurons

Stefanie Kaech et al.

NATURE PROTOCOLS (2006)

Article Multidisciplinary Sciences

Centrosome localization determines neuronal polarity

FC de Anda et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

PIP3 is involved in neuronal polarization and axon formation

C Ménager et al.

JOURNAL OF NEUROCHEMISTRY (2004)

Article Multidisciplinary Sciences

Centrosome maturation: Measurement of microtubule nucleation throughout the cell cycle by using GFP-tagged EB1

M Piehl et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Cell Biology

The Golgi complex is a microtubule-organizing organelle

K Chabin-Brion et al.

MOLECULAR BIOLOGY OF THE CELL (2001)