相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden
Julia Femel et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2022)
Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens
Anna V. Blenda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2022)
Galectin-1 confers resistance to doxorubicin in hepatocellular carcinoma cells through modulation of P-glycoprotein expression
Pablo Carabias et al.
CELL DEATH & DISEASE (2022)
A roadmap for translational cancer glycoimmunology at single cell resolution
Andreia Peixoto et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2022)
Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm
Raquel Roldan-Montero et al.
SCIENCE ADVANCES (2022)
Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3
Chunjian Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease
Fredrik R. Zetterberg et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Characterization of a neutralizing anti-human galectin-1 monoclonal antibody with angioregulatory and immunomodulatory activities
Juan M. Perez Saez et al.
ANGIOGENESIS (2021)
Targeting the CRD F-face of Human Galectin-3 and Allosterically Modulating Glycan Binding by Angiostatic PTX008 and a Structurally Optimized Derivative
Michelle C. Miller et al.
CHEMMEDCHEM (2021)
Combinatorial Inhibition of Galectin-9 and CHK1 Represent a Novel Treatment Strategy for T-Cell Acute Lymphoblastic Leukemia
Miyoung Lee et al.
BLOOD (2021)
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
Nikhil Hirani et al.
EUROPEAN RESPIRATORY JOURNAL (2021)
Galectin-1-RNA interaction map reveals potential regulatory roles in angiogenesis
Jiajun Wei et al.
FEBS LETTERS (2021)
The therapeutic potential of galectin-3 inhibition in fibrotic disease
R. J. Slack et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2021)
Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin
Ashley J. Russo et al.
NATURE IMMUNOLOGY (2021)
Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy
Satyen H. Gohil et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2021)
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
Benjamin A. H. Smith et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Reprogramming the tumor metastasis cascade by targeting galectin-driven networks
Ramiro M. Perrotta et al.
BIOCHEMICAL JOURNAL (2021)
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy
Riyao Yang et al.
NATURE COMMUNICATIONS (2021)
Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies
Marina Stasenko et al.
SCIENTIFIC REPORTS (2021)
SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells
Conor J. Kearney et al.
SCIENCE ADVANCES (2021)
Modified Citrus Pectin Treatment in Non-Metastatic Biochemically Relapsed Prostate Cancer: Results of a Prospective Phase II Study
Daniel Keizman et al.
NUTRIENTS (2021)
Full-Length Galectin-3 Is Required for High Affinity Microbial Interactions and Antimicrobial Activity
Shang-Chuen Wu et al.
FRONTIERS IN MICROBIOLOGY (2021)
Mechanisms and disease consequences of nonalcoholic fatty liver disease
Rohit Loomba et al.
CELL (2021)
Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression
Seok-Jun Kim et al.
GASTRIC CANCER (2021)
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
Alvaro de Mingo Pulido et al.
IMMUNITY (2021)
Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors
Li Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8(+) regulatory T cells
Alejandro J. Cagnoni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Enhancing clinical and immunological effects of anti-PD-1 with belapectin, a galectin-3 inhibitor
Brendan D. Curti et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
New Treatment Strategy Targeting Galectin-1 against Thyroid Cancer
Laetitia Gheysen et al.
CELLS (2021)
Emerging role of galectin family in inflammatory autoimmune diseases
Wang-Dong Xu et al.
AUTOIMMUNITY REVIEWS (2021)
A minigene DNA vaccine encoding peptide epitopes derived from Galectin-1 has protective antitumoral effects in a model of neuroblastoma
Laura Liebscher et al.
CANCER LETTERS (2021)
Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3
Viktoria Heine et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Activated Galectin-9/Tim3 promotes Treg and suppresses Th1 effector function in chronic lymphocytic leukemia
Nannan Pang et al.
FASEB JOURNAL (2021)
Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits
Luciano G. Morosi et al.
SCIENCE ADVANCES (2021)
Galectin-1 impacts on glucose homeostasis by modulating pancreatic insulin release
Victoria Sundblad et al.
GLYCOBIOLOGY (2021)
A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1
Diana Shah et al.
ONCOIMMUNOLOGY (2021)
Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity
Elizabeth R. Sturgill et al.
ONCOIMMUNOLOGY (2021)
Galectin-3 Inhibition With Modified Citrus Pectin in Hypertension
Emily S. Lau et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2021)
Intracellular galectins sense cytosolically exposed glycans as danger and mediate cellular responses
Ming-Hsiang Hong et al.
JOURNAL OF BIOMEDICAL SCIENCE (2021)
Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension
Naga Chalasani et al.
GASTROENTEROLOGY (2020)
Sweetening the hallmarks of cancer: Galectins as multifunctional mediators of tumor progression
Maria Romina Girotti et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
In Vivo Veritas: 18F-Radiolabeled Glycomimetics Allow Insights into the Pharmacological Fate of Galectin-3 Inhibitors
Klas Bratteby et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Chemogenetic Control of Nanobodies
Helen Farrants et al.
NATURE METHODS (2020)
Epimers Switch Galectin-9 Domain Selectivity: 3N-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal
Mukul Mahanti et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Regioselective 3-O-Substitution of Unprotected Thiodigalactosides: Direct Route to Galectin Inhibitors
Tomas Vasicek et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Suppression of age-related salivary gland autoimmunity by glycosylation-dependent galectin-1-driven immune inhibitory circuits
Veronica C. Martinez Allo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Impact of Galectins in Resistance to Anticancer Therapies
Pilar Navarro et al.
CLINICAL CANCER RESEARCH (2020)
Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation
Chuan-xia Zhang et al.
ONCOGENESIS (2020)
Galectin-9 expression defines exhausted T cells and impaired cytotoxic NK cells in patients with virus-associated solid tumors
Isobel Okoye et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome
Carolina Tiraboschi et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
Efficient synthesis of a galectin inhibitor clinical candidate (TD139) using a Payne rearrangement/azidation reaction cascade
Jacob St-Gelais et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2020)
Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells
Yu-An Hsu et al.
JOURNAL OF BIOMEDICAL SCIENCE (2020)
Galectin-1 is a new fibrosis protein in type 1 and type 2 diabetes
Noor Al-Obaidi et al.
FASEB JOURNAL (2019)
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade
Lynda Vuong et al.
CANCER RESEARCH (2019)
Glycosylation in health and disease
Colin Reily et al.
NATURE REVIEWS NEPHROLOGY (2019)
Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading?
Stefan Mereiter et al.
CANCER CELL (2019)
Selective effects of ginseng pectins on galectin-3-mediated T cell activation and apoptosis
Huiting Xue et al.
CARBOHYDRATE POLYMERS (2019)
A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1
Kumar Bhaskar Pal et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The therapy of idiopathic pulmonary fibrosis: what is next?
Vivien Somogyi et al.
EUROPEAN RESPIRATORY REVIEW (2019)
Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance
Dhanya K. Nambiar et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells
Zoe Leung et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
The role of galectin-3 in heart failure and cardiovascular disease
Xiao Zhong et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2019)
A DNA Aptamer Targeting Galectin-1 as a Novel Immunotherapeutic Strategy for Lung Cancer
Yao-Tsung Tsai et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design
Carlos P. Modenutti et al.
FRONTIERS IN CHEMISTRY (2019)
Extracellular and intracellular small-molecule galectin-3 inhibitors
John Stegmayr et al.
SCIENTIFIC REPORTS (2019)
Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors
Alexander Dahlqvist et al.
MEDCHEMCOMM (2019)
Updates to the Symbol Nomenclature for Glycans guidelines
Sriram Neelamegham et al.
GLYCOBIOLOGY (2019)
Different angioregulatory activity of monovalent galectin-9 isoforms
Ed Aanhane et al.
ANGIOGENESIS (2018)
Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors
Hao Zhang et al.
BIOCONJUGATE CHEMISTRY (2018)
Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment
Maria T. Elola et al.
CELLULAR IMMUNOLOGY (2018)
Lactulose as a novel template for anticancer drug development targeting galectins
Chandan Kishor et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2018)
Monosaccharide Derivatives with Low-Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine-Amide, Phenyl-Arginine, Sulfur-pi, and Halogen Bond Interactions
Fredrik R. Zetterberg et al.
CHEMMEDCHEM (2018)
Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion
Tsung-Chieh Shih et al.
CLINICAL CANCER RESEARCH (2018)
Correlation between serum galectin-9 levels and liver fibrosis
Koji Fujita et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2018)
Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk
Carlos A. Orozco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Cancer immunotherapy using checkpoint blockade
Antoni Ribas et al.
SCIENCE (2018)
Untangling Galectin-Driven Regulatory Circuits in Autoimmune Inflammation
Marta A. Toscano et al.
TRENDS IN MOLECULAR MEDICINE (2018)
Chemoenzymatic Synthesis of Galectin Binding Glycopolymers
Jessica H. Ennist et al.
BIOCONJUGATE CHEMISTRY (2018)
Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin-glycan specificities in a natural context
Mathias Ingemann Nielsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Galectin-3 and cancer stemness
Pratima Nangia-Makker et al.
GLYCOBIOLOGY (2018)
The tumour glyco-code as a novel immune checkpoint for immunotherapy
Ernesto Rodriguez et al.
NATURE REVIEWS IMMUNOLOGY (2018)
Cytosolic galectin-3 and-8 regulate antibacterial autophagy through differential recognition of host glycans on damaged phagosomes
I-Chun Weng et al.
GLYCOBIOLOGY (2018)
RN1, a novel galectin-3 inhibitor, inhibits pancreatic cancer cell growth in vitro and in vivo via blocking galectin-3 associated signaling pathways
L. Zhang et al.
ONCOGENE (2017)
Galectin-1 Inhibitor OTX008 Induces Tumor Vessel Normalization and Tumor Growth Inhibition in Human Head and Neck Squamous Cell Carcinoma Models
Nathan A. Koonce et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells
Florent Colomb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance
Donnele Daley et al.
NATURE MEDICINE (2017)
Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
Ana L. Mora et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Translating the 'Sugar Code' into Immune and Vascular Signaling Programs
Juan P. Cerliani et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
The involvement of E6, p53, p16, MDM2 and Gal-3 in the clinical outcome of patients with cervical cancer
Annika Stiasny et al.
ONCOLOGY LETTERS (2017)
Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration
Monica Gordon-Alonso et al.
NATURE COMMUNICATIONS (2017)
Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers
Laetitia Seguin et al.
CANCER DISCOVERY (2017)
Glycosylation-dependent galectin-1/ neuropilin-1 interactions promote liver fibrosis through activation of TGF-β- and PDGF-like signals in hepatic stellate cells
Ming-Heng Wu et al.
SCIENTIFIC REPORTS (2017)
Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function
Tao Zhang et al.
BIOCHEMICAL JOURNAL (2017)
Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells
Tushar Piyush et al.
CELL DEATH AND DIFFERENTIATION (2017)
Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis
Santiago P. Mendez-Huergo et al.
CURRENT OPINION IN IMMUNOLOGY (2017)
Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis
Wei-Sheng Chen et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis
Jaymin J. Kathiriya et al.
CELL DEATH DISCOVERY (2017)
Binding of polysaccharides to human galectin-3 at a noncanonical site in its carbohydrate recognition domain
Michelle C. Miller et al.
GLYCOBIOLOGY (2016)
Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis
S. A. Harrison et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2016)
Galectins and Immune Responses-Just How Do They Do Those Things They Do?
Sandra Thiemann et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 34 (2016)
Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells
Peter P. Ruvolo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Galectin-3 interacts with components of the nuclear ribonucleoprotein complex
Katharina Fritsch et al.
BMC CANCER (2016)
Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Kosei Nakajima et al.
CANCER RESEARCH (2016)
Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition
Tamara Delaine et al.
CHEMBIOCHEM (2016)
Galectin-1 inhibitors and their potential therapeutic applications: a patent review
Helen Blanchard et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
Synthetic glycoconjugates inhibitors of tumor-related galectin-3: an update
Vanessa Leiria Campo et al.
GLYCOCONJUGATE JOURNAL (2016)
A key role for galectin-1 in sprouting angiogenesis revealed by novel rationally designed antibodies
Judy R. van Beijnum et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Biodegradable brush-type copolymer modified with targeting peptide as a nanoscopic platform for targeting drug delivery to treat castration-resistant prostate cancer
Tao Liu et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans
John Stegmayr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model
Vishal K. Rajput et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo
P. Storti et al.
LEUKEMIA (2016)
Recombinant adeno-associated virus-delivered anginex inhibits angiogenesis and growth of HUVECs by regulating the Akt, JNK and NF-κB signaling pathways
Ke Ma et al.
ONCOLOGY REPORTS (2016)
Glyco-nano-oncology: Novel therapeutic opportunities by combining small and sweet
Pablo F. Hockl et al.
PHARMACOLOGICAL RESEARCH (2016)
Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1
Xiao Na Ge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling
P-F Zhang et al.
CELL DEATH & DISEASE (2016)
An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells
Po-Chun Tseng et al.
ONCOTARGET (2016)
Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway
Yang Chong et al.
ONCOTARGET (2016)
Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells
Amelia J. Tesone et al.
CELL REPORTS (2016)
Role of Cytokine-Induced Glycosylation Changes in Regulating Cell Interactions and Cell Signaling in Inflammatory Diseases and Cancer
Justine H. Dewald et al.
CELLS (2016)
Turning-Off Signaling by Siglecs, Selectins, and Galectins: Chemical inhibition of Glycan-Dependent interactions in Cancer
Alejandro J. Cagnoni et al.
FRONTIERS IN ONCOLOGY (2016)
Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Tung-Ju Hsieh et al.
SCIENTIFIC REPORTS (2016)
Galectin expression in cancer diagnosis and prognosis: A systematic review
Victor L. Thijssen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2015)
Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation
Melanie R. Rutkowski et al.
CANCER CELL (2015)
The effect of the size of fluorescent dextran on its endocytic pathway
Lei Li et al.
CELL BIOLOGY INTERNATIONAL (2015)
Novel analogs of antitumor agent calixarene 0118: Synthesis, cytotoxicity, click labeling with 2-[18F]fluoroethylazide, and in vivo evaluation
Tilman Lappchen et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: In vivo evaluation
Fabienne Danhier et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Binding of Galectin-3, a β-Galactoside-binding Lectin, to MUC1 Protein Enhances Phosphorylation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Akt, Promoting Tumor Cell Malignancy
Yugo Mori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The galectin lattice at a glance
Ivan R. Nabi et al.
JOURNAL OF CELL SCIENCE (2015)
Galectin-1 Triggers Epithelial-Mesenchymal Transition in Human Hepatocellular Carcinoma Cells
Maria L. Bacigalupo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
Clinical experiences with systemically administered siRNA-based therapeutics in cancer
Jonathan E. Zuckerman et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
Carmel B. Nanthakumar et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Pectin in cancer therapy: A review
Wenbo Zhang et al.
TRENDS IN FOOD SCIENCE & TECHNOLOGY (2015)
Aflibercept Traps Galectin-1, an Angiogenic Factor Associated with Diabetic Retinopathy
Atsuhiro Kanda et al.
SCIENTIFIC REPORTS (2015)
Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation
Miguel Angel Burguillos et al.
CELL REPORTS (2015)
Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics
Alan Kirwan et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Galectin-3 Shapes Antitumor Immune Responses by Suppressing CD8+ T Cells via LAG-3 and Inhibiting Expansion of Plasmacytoid Dendritic Cells
Theodore Kouo et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Samy Cecioni et al.
CHEMICAL REVIEWS (2015)
Heat-Modified Citrus Pectin Induces Apoptosis-Like Cell Death and Autophagy in HepG2 and A549 Cancer Cells
Lionel Leclere et al.
PLOS ONE (2015)
Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion
Thapi D. Rao et al.
PLOS ONE (2015)
Aberrant Glycosylation Promotes Lung Cancer Metastasis through Adhesion to Galectins in the Metastatic Niche
Nathan E. Reticker-Flynn et al.
CANCER DISCOVERY (2015)
Inhibition of malignant thyroid carcinoma cell proliferation by Ras and galectin-3 inhibitors
A. Menachem et al.
CELL DEATH DISCOVERY (2015)
Galectin Binding to Neo-Glycoproteins: LacDiNAc Conjugated BSA as Ligand for Human Galectin-3
Sophia Boecker et al.
BIOMOLECULES (2015)
Glycosylation in cancer: mechanisms and clinical implications
Salome S. Pinho et al.
NATURE REVIEWS CANCER (2015)
Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer
Pablo Argueeso et al.
TISSUE BARRIERS (2015)
Galectin-1 induces vascular permeability through the neuropilin-1/vascular endothelial growth factor receptor-1 complex
Ming-Heng Wu et al.
ANGIOGENESIS (2014)
Inhibitors of Galectins and Implications for Structure-Based Design of Galectin-Specific Therapeutics
Helen Blanchard et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2014)
Endothelial LGALS9 splice variant expression in endothelial cell biology and angiogenesis
Roy Heusschen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists
Vishal Kumar Rajput et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Abstract 33: OTX008 pharmacokinetics (PK) during the first-in-man phase I study in patients with advanced solid tumors .
Keyvan Rezai et al.
CANCER RESEARCH (2014)
Natural Killer Cells Eradicate Galectin-1-Deficient Glioma in the Absence of Adaptive Immunity
Gregory J. Baker et al.
CANCER RESEARCH (2014)
Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors
Diego O. Croci et al.
CELL (2014)
Galectin-1 Mediates Radiation-Related Lymphopenia and Attenuates NSCLC Radiation Response
Peiwen Kuo et al.
CLINICAL CANCER RESEARCH (2014)
OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis
Lucile Astorgues-Xerri et al.
EUROPEAN JOURNAL OF CANCER (2014)
Induction of galectin-1 by TGF-β1 accelerates fibrosis through enhancing nuclear retention of Smad2
Min Jin Lim et al.
EXPERIMENTAL CELL RESEARCH (2014)
Structural basis of redox-dependent modulation of galectin-1 dynamics and function
Carlos M. Guardia et al.
GLYCOBIOLOGY (2014)
Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancer
Leonardo Mirandola et al.
GYNECOLOGIC ONCOLOGY (2014)
Design and Synthesis of Hydrolytically Stable Multivalent Ligands Bearing Thiodigalactoside Analogues for Peanut Lectin and Human Galectin-3 Binding
Alejandro J. Cagnoni et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha-1 Antitrypsin in Acute and Chronic Inflammatory Conditions
Cormac McCarthy et al.
JOURNAL OF PROTEOME RESEARCH (2014)
Targeting Prostate Carcinoma by G3-C12 Peptide Conjugated N-(2-Hydroxypropyl)methacrylamide Copolymers
Yang Yang et al.
MOLECULAR PHARMACEUTICS (2014)
Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors
V. Veschi et al.
CELL DEATH & DISEASE (2014)
An In Vivo Functional Screen Identifies ST6GalNAc2 Sialyltransferase as a Breast Cancer Metastasis Suppressor
Nirupa Murugaesu et al.
CANCER DISCOVERY (2014)
Linking tumor hypoxia with VEGFR2 signaling and compensatory angiogenesis Glycans make the difference
Diego O. Croci et al.
ONCOIMMUNOLOGY (2014)
Galectin-1 Controls Cardiac Inflammation and Ventricular Remodeling during Acute Myocardial Infarction
Ignacio M. Seropian et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3
Helen Wang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib
Massimo Zucchetti et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2013)
Targeting Galectin-1 Overcomes Breast Cancer-Associated Immunosuppression and Prevents Metastatic Disease
Tomas Dalotto-Moreno et al.
CANCER RESEARCH (2013)
A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
Diego J. Laderach et al.
CANCER RESEARCH (2013)
Increased Circulation of Galectin-3 in Cancer Induces Secretion of Metastasis-Promoting Cytokines from Blood Vascular Endothelium
Chen Chen et al.
CLINICAL CANCER RESEARCH (2013)
Vascular galectins: Regulators of tumor progression and targets for cancer therapy
Victor L. Thijssen et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2013)
Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice
Alison C. MacKinnon et al.
GLYCOBIOLOGY (2013)
Polycationic calixarene PTX013, a potent cytotoxic agent against tumors and drug resistant cancer
Ruud P. M. Dings et al.
INVESTIGATIONAL NEW DRUGS (2013)
Overexpression of galectin-3 enhances migration of colon cancer cells related to activation of the K-Ras-Raf-Erk1/2 pathway
Keng-Liang Wu et al.
JOURNAL OF GASTROENTEROLOGY (2013)
Tuning the Preference of Thiodigalactoside- and Lactosamine-Based Ligands to Galectin-3 over Galectin-1
Hilde van Hattum et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Density-dependent Lectin-Glycan Interactions as a Paradigm for Conditional Regulation by Posttranslational Modifications
James W. Dennis et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
A Possible Role of Galectin-9 in the Pulmonary Fibrosis of Patients with Interstitial Pneumonia
Nobuhiro Matsumoto et al.
LUNG (2013)
Galectin-3 Accelerates the Progression of Oral Tongue Squamous Cell Carcinoma via a Wnt/beta-catenin-Dependent Pathway
Li-Ping Wang et al.
PATHOLOGY & ONCOLOGY RESEARCH (2013)
Therapy of Experimental NASH and Fibrosis with Galectin Inhibitors
Peter G. Traber et al.
PLOS ONE (2013)
Regression of Fibrosis and Reversal of Cirrhosis in Rats by Galectin Inhibitors in Thioacetamide-Induced Liver Disease
Peter G. Traber et al.
PLOS ONE (2013)
Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis
Prasun Guha et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Structure-Based Optimization of Angiostatic Agent 6DBF7, an Allosteric Antagonist of Galectin-1
Ruud P. M. Dings et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
Regulation of Transforming Growth Factor-β1-driven Lung Fibrosis by Galectin-3
Alison C. MacKinnon et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Peptide-Drug Conjugate Linked via a Disulfide Bond for Kidney Targeted Drug Delivery
Qian Geng et al.
BIOCONJUGATE CHEMISTRY (2012)
Treatment of prostate carcinoma with (Galectin-3)-targeted HPMA copolymer-(G3-C12)-5-Fluorouracil conjugates
Yang Yang et al.
BIOMATERIALS (2012)
Taloside Inhibitors of Galectin-1 and Galectin-3
Patrick M. Collins et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2012)
Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor
Geoffrey Masuyer et al.
FEBS JOURNAL (2012)
Structural features for α-galactomannan binding to galectin-1
Michelle C. Miller et al.
GLYCOBIOLOGY (2012)
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss
Rosanna E. Ramhorst et al.
GLYCOBIOLOGY (2012)
Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer
Gabriel A. Rabinovich et al.
IMMUNITY (2012)
Galectin-1 Deactivates Classically Activated Microglia and Protects from Inflammation-Induced Neurodegeneration
Sarah C. Starossom et al.
IMMUNITY (2012)
Galectin-3 Protein Regulates Mobility of N-cadherin and GM1 Ganglioside at Cell-Cell Junctions of Mammary Carcinoma Cells
Cecile Boscher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma
Diego O. Croci et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Galectin-1 Triggers an Immunoregulatory Signature in Th Cells Functionally Defined by IL-10 Expression
Filiberto Cedeno-Laurent et al.
JOURNAL OF IMMUNOLOGY (2012)
Galectin-3 Regulates Intracellular Trafficking of EGFR through Alix and Promotes Keratinocyte Migration
Wei Liu et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
Antitumor Agent Calixarene 0118 Targets Human Galectin-1 as an Allosteric Inhibitor of Carbohydrate Binding
Ruud P. M. Dings et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again
Santiago Di Lella et al.
BIOCHEMISTRY (2011)
Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders
Jing Ouyang et al.
BLOOD (2011)
Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis
Alice Banh et al.
CANCER RESEARCH (2011)
Arene-Anion Based Arginine-Binding Motif on a Galactose Scaffold: Structure-Activity Relationships of Interactions with Arginine-Rich Galectins
Christopher T. Oberg et al.
CHEMISTRY-A EUROPEAN JOURNAL (2011)
Galectin-3 Protein Modulates Cell Surface Expression and Activation of Vascular Endothelial Growth Factor Receptor 2 in Human Endothelial Cells
Anna I. Markowska et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
The Anti-angiogenic Peptide Anginex Greatly Enhances Galectin-1 Binding Affinity for Glycoproteins
Emma Salomonsson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer
Eva Kopansky et al.
JOURNAL OF DRUG TARGETING (2011)
Galectin-3 ablation protects mice from diet-induced NASH: A major scavenging role for galectin-3 in liver
Carla Iacobini et al.
JOURNAL OF HEPATOLOGY (2011)
Molecular mechanisms and clinical applications of angiogenesis
Peter Carmeliet et al.
NATURE (2011)
Galectin-3C Inhibits Tumor Growth and Increases the Anticancer Activity of Bortezomib in a Murine Model of Human Multiple Myeloma
Leonardo Mirandola et al.
PLOS ONE (2011)
Galectins: regulators of acute and chronic inflammation
Fu-Tong Liu et al.
YEAR IN IMMUNOLOGY 2 (2010)
Effect of citrus pectin on malignant cell proliferation
M. Bergman et al.
BIOMEDICINE & PHARMACOTHERAPY (2010)
1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors
Bader A. Salameh et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death
Matthew J. Streetly et al.
BLOOD (2010)
Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity
Victor L. Thijssen et al.
CANCER RESEARCH (2010)
A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice
Nathalie Demotte et al.
CANCER RESEARCH (2010)
Multimeric Lactoside Click Clusters as Tools to Investigate the Effect of Linker Length in Specific Interactions with Peanut Lectin, Galectin-1, and-3
Sebastien G. Gouin et al.
CHEMBIOCHEM (2010)
PectaSol-C Modified Citrus Pectin Induces Apoptosis and Inhibition of Proliferation in Human and Mouse Androgen-Dependent and -Independent Prostate Cancer Cells
Jun Yan et al.
INTEGRATIVE CANCER THERAPIES (2010)
Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer
Pratima Nangia-Makker et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response
Anna I. Markowska et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Allergen-Induced Airway Remodeling Is Impaired in Galectin-3-Deficient Mice
Xiao Na Ge et al.
JOURNAL OF IMMUNOLOGY (2010)
Development trends for human monoclonal antibody therapeutics
Aaron L. Nelson et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Modified citrus pectin anti-metastatic properties: one bullet, multiple targets
Vladislav V. Glinsky et al.
CARBOHYDRATE RESEARCH (2009)
The α-galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain
Michelle C. Miller et al.
GLYCOBIOLOGY (2009)
The regulation of inflammation by galectin-3
Neil C. Henderson et al.
IMMUNOLOGICAL REVIEWS (2009)
Ligand Reduces Galectin-1 Sensitivity to Oxidative Inactivation by Enhancing Dimer Formation
Sean R. Stowell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Galectin-1 Tunes TCR Binding and Signal Transduction to Regulate CD8 Burst Size
Scot D. Liu et al.
JOURNAL OF IMMUNOLOGY (2009)
Galectin-3 Targeted Therapy with a Small Molecule Inhibitor Activates Apoptosis and Enhances Both Chemosensitivity and Radiosensitivity in Papillary Thyroid Cancer
Chi-lou Lin et al.
MOLECULAR CANCER RESEARCH (2009)
Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10
Juan M. Ilarregui et al.
NATURE IMMUNOLOGY (2009)
Roles of galectins in infection
Gerardo R. Vasta
NATURE REVIEWS MICROBIOLOGY (2009)
Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3
Johan Tejler et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2009)
Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse
Huan-Yuan Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation
Gabriel A. Rabinovich et al.
NATURE REVIEWS IMMUNOLOGY (2009)
Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis
Neil C. Henderson et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Calix[n]arene-based glycoclusters:: Bioactivity of thiourea-linked galactose/lactose moieties as inhibitors of binding of medically relevant lectins to a glycoprotein and cell-surface glycoconjugates and selectivity among human adhesion/growth-regulatory galectins
Sabine Andre et al.
CHEMBIOCHEM (2008)
Double affinity amplification of galectin-ligand interactions through arginine-arene interactions: Synthetic, thermodynamic, and computational studies with aromatic diamido thiodigalactosides
Ian Cumpstey et al.
CHEMISTRY-A EUROPEAN JOURNAL (2008)
Galectins: structure, function and therapeutic potential
Ri-Yao Yang et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2008)
Galectin-1,-2, and-3 exhibit differential recognition of sialylated glycans and blood group antigens
Sean R. Stowell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Regulation of alternative macrophage activation by galectin-3
Alison C. MacKinnon et al.
JOURNAL OF IMMUNOLOGY (2008)
Arginine binding motifs:: Design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors
Christopher T. Oberg et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Galectin-Inhibitory Thiodigalactoside Ester Derivatives Have Antimigratory Effects in Cultured Lung and Prostate Cancer Cells
Tamara Delaine et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Galectin-1 is a novel structural component and a major regulator of H-Ras nanoclusters
Liron Belanis et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
Protein-glycan interactions in the control of innate and adaptive immune responses
Yvette van Kooyk et al.
NATURE IMMUNOLOGY (2008)
Galectin-1, a novel ligand of neuropilin-1, activates VEGFR-2 signaling and modulates the migration of vascular endothelial cells
S. H. Hsieh et al.
ONCOGENE (2008)
Functions of cell surface galectin-glycoprotein lattices
Gabriel A. Rabinovich et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2007)
A journey in structure-based drug discovery: From designed peptides to protein surface topomimetics as antibiotic and Antiangiogenic agents
Ruud P. M. Dings et al.
ACCOUNTS OF CHEMICAL RESEARCH (2007)
Synthesis of galactose-mimicking 1H-(l,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors
Johan Tejler et al.
CARBOHYDRATE RESEARCH (2007)
The AP1-dependent secretion of galectin-1 by Reed - Sternberg cells fosters immune privilege in classical Hodgkin lymphoma
Przemyslaw Juszczynski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
Marta A. Toscano et al.
NATURE IMMUNOLOGY (2007)
Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation
Ken S. Lau et al.
CELL (2007)
Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy
Victor L. J. L. Thijssen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Glycosylation in cellular mechanisms of health and disease
Kazuaki Ohtsubo et al.
CELL (2006)
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
NC Henderson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The anti-angiogenic peptide anginex disrupts the cell membrane
J Pilch et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectin-mediated homotypic cell aggregation and endothelial cell morphogenesis
GA Rabinovich et al.
GLYCOBIOLOGY (2006)
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
BN Stillman et al.
JOURNAL OF IMMUNOLOGY (2006)
IL-13 signaling through the IL-13 alpha 2 receptor is involved in induction of TGF-beta 1 production and fibrosis
S Fichtner-Feigl et al.
NATURE MEDICINE (2006)
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
C Zhu et al.
NATURE IMMUNOLOGY (2005)
A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells
D Chauhan et al.
CANCER RESEARCH (2005)
Cloning an artificial gene encoding angiostatic anginex: From designed peptide to functional recombinant protein
RJMGE Brandwijk et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Glycans in cancer and inflammation. Potential for therapeutics and diagnostics
DH Dube et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Structural and thermodynamic studies on cation -: II: interactions in lectin-ligand complexes:: High-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction
P Sörme et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
J Zou et al.
CARCINOGENESIS (2005)
Galectins as modulators of tumour progression
FT Liu et al.
NATURE REVIEWS CANCER (2005)
Synthesis of a phenyl thio-beta-D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: discovery of effcient and selective monosaccharide inhibitors of galectin-7
I Cumpstey et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2005)
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection: A potential mechanism of tumor-immune privilege
N Rubinstein et al.
CANCER CELL (2004)
Comparative cell response to artificial extracellular matrix proteins containing the RGD and CS5 cell-binding domains
JC Liu et al.
BIOMACROMOLECULES (2004)
Galectin-3, a novel binding partner of β-catenin
T Shimura et al.
CANCER RESEARCH (2004)
Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity
G Elad-Sfadia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins
O Blixt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis
EA Partridge et al.
SCIENCE (2004)
Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets
S Andre et al.
BIOCONJUGATE CHEMISTRY (2004)
Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity
KH Mayo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot study
BW Guess et al.
PROSTATE CANCER AND PROSTATIC DISEASES (2003)
Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin
P Nangia-Makker et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2002)
The designer antiangiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models
DWJ van der Schaft et al.
FASEB JOURNAL (2002)
Intracellular functions of galectins
FT Liu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2002)
Enhanced delivery of naked DNA to the skin by non-invasive in vivo electroporation
L Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2002)
Interleukin-4 regulates connective tissue growth factor expression in human lung fibroblasts
DC Rishikof et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation
A Paz et al.
ONCOGENE (2001)
Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein
JW Park et al.
NUCLEIC ACIDS RESEARCH (2001)
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures
H Lahm et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2001)
分享论文
