Catching active enhancers via H2B N-terminal acetylation

Specific chromatin features, especially histone H3 lysine 27 acetylation, are widely used to identify active enhancers, yet current methods are imprecise. New work suggests that histone H2B N terminus multisite lysine acetylation (H2BNTac) is a notable signature of active enhancers and could substantially improve enhancer prediction.

Automated summary

New research suggests that histone H2B N terminus multisite lysine acetylation (H2BNTac) is a significant characteristic of active enhancers and could greatly enhance enhancer prediction accuracy.