Monitoring lysosomal acidity

Lysosomal hyperacidification is regarded as a hallmark of autophagy. A new pH nanosensor that detects shifts in near-infrared emission bands is used to quantify cellular and intratumoral lysosomal pH.

Automated summary

A new pH nanosensor is developed to quantify the acidity level of lysosomes in cells and tumors by detecting shifts in near-infrared emission bands.