A recent study reveals that the metabolic enzyme creatinine kinase B (CKB) phosphorylates the protein GPX4, which could potentially affect the susceptibility of cancer cells to ferroptosis.
The selenoprotein glutathione peroxidase 4 (GPX4) is the guardian of ferroptosis, a form of cell death earmarked by unrestrained lipid peroxidation. A new study shows that the metabolic enzyme creatinine kinase B (CKB) phosphorylates GPX4, which may influence the susceptibility of cancer cells to ferroptosis.
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