相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The G protein database, GproteinDb
Gaspar Pandy-Szekeres et al.
NUCLEIC ACIDS RESEARCH (2022)
The IUPHAR/BPS guide to PHARMACOLOGY in 2022: curating pharmacology for COVID-19, malaria and antibacterials
Simon D. Harding et al.
NUCLEIC ACIDS RESEARCH (2022)
Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
Charlotte Avet et al.
ELIFE (2022)
GPCRdb in 2021: integrating GPCR sequence, structure and function
Albert J. Kooistra et al.
NUCLEIC ACIDS RESEARCH (2021)
GPCR activation mechanisms across classes and macro/microscales
Alexander S. Hauser et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2021)
β2-adrenoceptor ligand efficacy is tuned by a two-stage interaction with the Gαs C terminus
Keehun Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator
Adrian L. Sanborn et al.
ELIFE (2021)
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
Qiufeng Liu et al.
NATURE CHEMICAL BIOLOGY (2021)
Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane
Ning Ma et al.
BIOCHEMISTRY (2020)
Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A2A Receptor
Sangbae Lee et al.
STRUCTURE (2019)
Structural Insights into the Process of GPCR-G Protein Complex Formation
Xiangyu Liu et al.
CELL (2019)
Conformational plasticity of the intracellular cavity of GPCR-G-protein complexes leads to G-protein promiscuity and selectivity
Manbir Sandhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Illuminating G-Protein-Coupling Selectivity of GPCRs
Asuka Inoue et al.
CELL (2019)
SWISS-MODEL: homology modelling of protein structures and complexes
Andrew Waterhouse et al.
NUCLEIC ACIDS RESEARCH (2018)
The Molecular Basis of G Protein-Coupled Receptor Activation
William I. Weis et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 87 (2018)
Bitopic Inhibition of ATP and Substrate Binding in Ser/Thr Kinases through a Conserved Allosteric Mechanism
Ning Ma et al.
BIOCHEMISTRY (2018)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
A Scale of Agonism and Allosteric Modulation for Assessment of Selectivity, Bias, and Receptor Mutation
Terry Kenakin
MOLECULAR PHARMACOLOGY (2017)
Selectivity determinants of GPCR-G-protein binding
Tilman Flock et al.
NATURE (2017)
Priming GPCR signaling through the synergistic effect of two G proteins
Tejas M. Gupte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells
Lisa Seidal et al.
ELIFE (2017)
Understanding the GPCR biased signaling through G protein and arrestin complex structures
X. Edward Zhou et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
Christopher Southan et al.
NUCLEIC ACIDS RESEARCH (2016)
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
Dean P. Staus et al.
NATURE (2016)
β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop
Matthew T. Eddy et al.
STRUCTURE (2016)
Investigation of allosteric coupling in human β2-adrenergic receptor in the presence of intracellular loop 3
Canan Ozgur et al.
BMC STRUCTURAL BIOLOGY (2016)
Structural Dynamics and Thermostabilization of Neurotensin Receptor 1
Sangbae Lee et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2015)
Structured and disordered facets of the GPCR fold
A. J. Venkatakrishnan et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2014)
Development and Characterization of Pepducins as Gs-biased Allosteric Agonists
Richard Carr et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells
Rabia U. Malik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Improved Parameters for the Martini Coarse-Grained Protein Force Field
Djurre H. de Jong et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody
Aaron M. Ring et al.
NATURE (2013)
Effect of intracellular loop 3 on intrinsic dynamics of human β2-adrenergic receptor
Ozer Ozcan et al.
BMC STRUCTURAL BIOLOGY (2013)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
MSMBuilder2: Modeling Conformational Dynamics on the Picosecond to Millisecond Scale
Kyle A. Beauchamp et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Two distinct conformations of helix 6 observed in antagonist-bound structures of a β1-adrenergic receptor
Rouslan Moukhametzianov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Single-molecule dynamics of gating in a neurotransmitter transporter homologue
Yongfang Zhao et al.
NATURE (2010)
Monitoring protein interactions and dynamics with solvatochromic fluorophores
Galen S. Loving et al.
TRENDS IN BIOTECHNOLOGY (2010)
Fine-tuning of GPCR activity by receptor-interacting proteins
Stefanie L. Ritter et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Detergent binding explains anomalous SDS-PAGE migration of membrane proteins
Arianna Rath et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol
Huanting Liu et al.
BMC BIOTECHNOLOGY (2008)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
The MARTINI force field: Coarse grained model for biomolecular simulations
Siewert J. Marrink et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2007)
Genetic incorporation of unnatural amino acids into proteins in mammalian cells
Wenshe Liu et al.
NATURE METHODS (2007)
G protein-coupled receptors show unusual patterns of intrinsic unfolding
VP Jaakola et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2005)
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
L Covic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Agonist-induced conformational changes in the G-protein-coupling domain of the β2 adrenergic receptor
P Ghanouni et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)