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Massive mosquito factory in Brazil aims to halt dengue

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Article Infectious Diseases

Estimating the effect of the wMel release programme on the incidence of dengue and chikungunya in Rio de Janeiro, Brazil: a spatiotemporal modelling study

Gabriel Ribeiro Dos Santos et al.

Summary: The large-scale release of Wolbachia-infected mosquitoes in Rio de Janeiro, Brazil, resulted in a significant reduction in dengue and chikungunya incidence. The incomplete introgression of Wolbachia and the geographical diversity of the area may have contributed to the variation in the results of the release.

LANCET INFECTIOUS DISEASES (2022)

Article Medicine, General & Internal

Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue

A. Utarini et al.

Summary: The cluster-randomized trial in Indonesia showed that deploying mosquitoes infected with the wMel strain of Wolbachia pipientis led to a reduction in symptomatic, virologically confirmed dengue infections and hospitalizations among residents.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Infectious Diseases

Effectiveness of Wolbachia-infected mosquito deployments in reducing the incidence of dengue and other Aedes-borne diseases in Niteroi, Brazil: A quasi-experimental study

Sofia B. Pinto et al.

Summary: The introduction of the wMel strain of the bacterium Wolbachia into Aedes aegypti mosquitoes has been shown to significantly reduce the transmission of dengue, chikungunya, and Zika viruses. In a study conducted in Niteroi, Brazil, it was found that after three years of releases, there was a significant reduction in dengue, chikungunya, and Zika incidence in areas where the wMel-infected mosquitoes were deployed. This approach proved effective in reducing Aedes-borne diseases, even in environments with moderate and spatially heterogeneous prevalence of the wMel bacteria.

PLOS NEGLECTED TROPICAL DISEASES (2021)