Novel Synthesis of Dihydroisoxazoles by p-TsOH-Participated 1,3-Dipolar Cycloaddition of Dipolarophiles withα-Nitroketones

This article reports in detail a method for the synthesis of 3-benzoxoxazoline by the reaction of alkenes (alkynes) and a variety of a-nitroketones in the presence of p-TsOH. The scope of alkenes is broad, including different alkenes and the alkyne. This reaction provides a convenient and efficient synthetic method of 3-benzoylisoxazolines.

Automated summary

This article presents a detailed method for synthesizing 3-benzoxoxazoline using alkenes (alkynes) and various α-nitroketones in the presence of p-TsOH. The reaction covers a wide range of alkenes, including different alkenes and alkynes. This reaction offers a convenient and efficient approach for synthesizing 3-benzoylisoxazolines.