New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine

The strategic fluorination of oxidatively vulnerable sites in bioactive compounds is a relatively recent, widely used approach allowing us to modulate the stability, bio-absorption, and overall efficiency of pharmaceutical drugs. On the other hand, natural and tailor-made amino acids are traditionally used as basic scaffolds for the development of bioactive molecules. The main goal of this review article is to emphasize these general trends featured in recently approved pharmaceutical drugs.

Automated summary

The strategic fluorination in pharmaceutical drugs allows us to manipulate their stability, bio-absorption, and overall efficiency. Additionally, natural and tailor-made amino acids serve as essential frameworks for the development of bioactive molecules. This review article highlights these prevalent trends in recently approved drugs.