☆ 4.7 Article

Antarctic Krill Oil Exhibited Synergistic Effects with Nobiletin and Theanine on Regulating Ligand-Specific Receptor-Mediated Transcytosis in Blood-Brain Barrier by Inhibiting Alkaline Phosphatase in SAMP8 Mice

MOLECULAR NUTRITION & FOOD RESEARCH (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Food Science & Technology

Dietary Antarctic Krill Oil Enhances the Oral Bioavailability of Nobiletin but Has No Ideal Synergistic Effect on Improving Memory and Cognition Ability in Aβ1-42 Induced Rats

Jing-Ya Kong et al.

Summary: This study found that Antarctic krill oil (AKO) can enhance the oral bioavailability of Nobiletin (Nob) and facilitate its neuroprotective effect. The combination of AKO and Nob can reverse cognitive and learning defects induced by A beta(1-42) injection, but does not have an ideal synergistic effect compared to AKO or Nob alone. Further molecular experiments reveal that the neuroprotective effect may be attributed to the reduction of oxidative stress, inhibition of apoptosis and tau phosphorylation, and improvement of neurotrophic activity.

EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY (2022)

添加到收藏夹

Article Geriatrics & Gerontology

Antarctic krill oil exhibited synergistic effects with nobiletin and theanine in ameliorating memory and cognitive deficiency in SAMP8 mice: Applying the perspective of the sea-land combination to retard brain aging

Cheng-Cheng Wang et al.

Summary: The study found that the combination of sea-derived Antarctic krill oil (AKO) with land-derived nobiletin (Nob) and L-theanine (The) can effectively improve memory loss and cognitive deficiency in senescence-accelerated prone 8 mice (SAMP8).

FRONTIERS IN AGING NEUROSCIENCE (2022)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism

Nada A. Abumrad et al.

Summary: This review summarizes the importance of lipid uptake and metabolism in key organs, emphasizing the role of endothelial cell receptors and uptake pathways in regulating fatty acids and cholesterol uptake. Clinical and experimental data highlight the impact of endothelial cells on lipid supply to tissues, specifically the heart and arterial wall, and how it affects organ metabolism and function. Models suggest that receptor-mediated processes play a significant role in lipid uptake in various physiological and pathological conditions.

CIRCULATION RESEARCH (2021)

添加到收藏夹

Review Medicine, General & Internal

Alzheimer's disease

Philip Scheltens et al.

Summary: Alzheimer's disease is projected to see a significant increase in prevalence in the future, with genetics playing a key role. Novel biomarkers and lifestyle-based prevention trials show promising therapeutic potential. Promising pharmacological treatments are advancing in clinical trials, targeting amyloid beta, tau, and inflammation.

LANCET (2021)

添加到收藏夹

Article Food Science & Technology

Dietary EPA-Enriched Phospholipids Alleviate Chronic Stress and LPS-Induced Depression- and Anxiety-Like Behavior by Regulating Immunity and Neuroinflammation

Cheng-Cheng Wang et al.

Summary: Comparative investigation showed that dietary EPA-PL had superior effects in alleviating depression- and anxiety-like behavior compared to EPA-EE. Further studies revealed that EPA-PL regulated immunity, monoamine systems, and the HPA axis through multi-target interactions, including inhibition of neuroinflammation and apoptosis.

MOLECULAR NUTRITION & FOOD RESEARCH (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Physiological blood-brain transport is impaired with age by a shift in transcytosis

Andrew C. Yang et al.

NATURE (2020)

添加到收藏夹

Article Neurosciences

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer's Disease Model

Mario Merlini et al.

NEURON (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

Stephen S. Dominy et al.

SCIENCE ADVANCES (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease

Akira Nakajima et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

Nobiletin Inhibits Cell Viability via the SRC/AKT/STAT3/YY1AP1 Pathway in Human Renal Carcinoma Cells

Di Wei et al.

FRONTIERS IN PHARMACOLOGY (2019)

添加到收藏夹

Review Cell Biology

Steroid receptor/coactivator binding inhibitors: An update

Kornelia J. Skowron et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Comparative studies of DHA- enriched phosphatidylcholine and recombination of DHAethyl ester with egg phosphatidylcholine on ameliorating memory and cognitive deficiency in SAMP8 mice+

Cheng-Cheng Wang et al.

FOOD & FUNCTION (2019)

添加到收藏夹

Review Neurosciences

Role of Blood-Brain Barrier in Alzheimer's Disease

Zhiyou Cai et al.

JOURNAL OF ALZHEIMERS DISEASE (2018)

添加到收藏夹

Review Neurosciences

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

Mark A. Petersen et al.

NATURE REVIEWS NEUROSCIENCE (2018)

添加到收藏夹

Review Geriatrics & Gerontology

Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer's Disease

Ruth F. Itzhaki

FRONTIERS IN AGING NEUROSCIENCE (2018)

添加到收藏夹

Review Food Science & Technology

L-theanine, unique amino acid of tea, and its metabolism, health effects, and safety

Duygu Turkozu et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2017)

添加到收藏夹

Review Pharmacology & Pharmacy

Pathways of protein and lipid receptor-mediated transcytosis in drug delivery

Roland Thuenauer et al.

EXPERT OPINION ON DRUG DELIVERY (2017)

添加到收藏夹

Review Immunology

Alzheimer's disease: A matter of blood-brain barrier dysfunction?

Axel Montagne et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

添加到收藏夹

Article Neurosciences

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

Benjamin J. Andreone et al.

NEURON (2017)

添加到收藏夹

Review Neurosciences

Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer's and Parkinson's Disease

Nady Braidy et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2017)

添加到收藏夹

Article Cell Biology

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome

Baokun He et al.

CELL METABOLISM (2016)

添加到收藏夹

Review Cell Biology

Caveolae: One Function or Many?

Jade P. X. Cheng et al.

TRENDS IN CELL BIOLOGY (2016)

添加到收藏夹

Review Geriatrics & Gerontology

Hormesis: why it is important to biogerontologists

Edward J. Calabrese et al.

BIOGERONTOLOGY (2012)

添加到收藏夹

Article Clinical Neurology

Alkaline Phosphatase Is Increased in both Brain and Plasma in Alzheimer's Disease

Emma R. L. C. Vardy et al.

NEURODEGENERATIVE DISEASES (2012)

添加到收藏夹

Review Neurosciences

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

Berislav V. Zlokovic

NATURE REVIEWS NEUROSCIENCE (2011)

添加到收藏夹

Review Biochemistry & Molecular Biology

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

Vittorio Calabrese et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

添加到收藏夹

Article Cell Biology

Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

M Murshed et al.

GENES & DEVELOPMENT (2005)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.