期刊
MATERIALS LETTERS
卷 336, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.matlet.2023.133885
关键词
Chitosan; Eudragit; Poly(4-vinylpyridine); Silver nanoparticles; Electrophoretic deposition; Biological properties
The aim of this study was to investigate the response of coatings composed of chitosan (CS), Eudragit E 100 (EE100), or poly(4-vinylpyridine) (P4VP) on a silver nanoparticle (AgNPs)-decorated titanium substrate when in contact with human osteoblast-like MG-63 cells. The biopolymer coatings were successfully deposited on the substrate with high uniformity, and the deposited silver did not exhibit cytotoxicity. The biological study showed that the CS/EE100 coating performed better than the CS/P4VP coating, with a decrease in MG-63 cell viability observed only after three days of testing.
The objective of the study was the determination of the response, in contact with human osteoblast-like MG-63 cells, of electrophoretically deposited coatings composed of chitosan (CS), Eudragit E 100 (EE100), or poly(4-vinylpyridine) (P4VP) on a silver nanoparticle (AgNPs)-decorated titanium substrate. Before deposition, the substrate was coated with silver by electro-reduction of silver nitrate. The coatings deposition was carried out in suspensions containing 0.1 % (w/w) of one of the biopolymers, EE100 or P4VP, with 0.1 % (w/w) of CS for 10 V and 1 min. Biopolymer coatings were successfully deposited while maintaining high uniformity. The deposited silver did not cause cytotoxicity. The biological study revealed that when compared to CS/P4VP, CS/EE100 coating performed better and showed a decrease in MG-63 cell viability only after three days of testing.
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