4.7 Review

Diatom-Based Nanomedicine for Colorectal Cancer Treatment: New Approaches for Old Challenges

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Engineering, Biomedical

Microfluidic-Assisted Production of Gastro-Resistant Active-Targeted Diatomite Nanoparticles for the Local Release of Galunisertib in Metastatic Colorectal Cancer Cells

Chiara Tramontano et al.

Summary: A nanoparticle-based drug delivery system has been developed for oral administration, which targets colorectal cancer cells and enhances drug efficacy.

ADVANCED HEALTHCARE MATERIALS (2023)

Article Oncology

Clinical management of metastatic colorectal cancer in the era of precision medicine

Fortunato Ciardiello et al.

Summary: This review summarizes the progress in the clinical management of patients with metastatic colorectal cancer (mCRC) in the era of precision medicine. Molecular stratification, based on the current treatment algorithm, has been a significant step towards implementing more effective therapeutic approaches. Integrating tumor gene alterations with tumor and microenvironment gene and protein expression profiling, host immune competence, and applying dynamic changes to precision medicine-based continuum of care, could lead to the identification of individual prognostic and predictive parameters for choosing the most appropriate therapeutic program for each patient.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Review Gastroenterology & Hepatology

Current and future colorectal cancer screening strategies

Aasma Shaukat et al.

Summary: This Review provides an overview of current CRC screening options worldwide, including colonoscopy and stool-based tests. It also highlights the key features of each modality and describes new screening tests under development.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2022)

Review Pharmacology & Pharmacy

The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor Microenvironment

Seong Keun Kim et al.

Summary: Immunotherapy has become an important approach in the field of cancer treatment. However, it has limitations and understanding the impact of the tumor microenvironment on its effectiveness is crucial in developing more effective cancer treatment strategies.

FRONTIERS IN PHARMACOLOGY (2022)

Article Pharmacology & Pharmacy

Nanoparticles: The future of effective diagnosis and treatment of colorectal cancer?

Reza Naeimi et al.

Summary: Colorectal cancer is a challenging malignancy in terms of diagnosis and treatment. Conventional methods lack accuracy and standard treatments often have side effects and drug resistance. Nanoparticles have emerged as promising candidates for improving diagnosis and treatment by enhancing drug targeting and solubility.

EUROPEAN JOURNAL OF PHARMACOLOGY (2022)

Review Oncology

Exploring immunotherapy in colorectal cancer

Junyong Weng et al.

Summary: Immunotherapy with immune checkpoint blockade has shown progress in the treatment of metastatic colorectal cancer (mCRC), although its effectiveness is limited. This review summarizes treatment strategies, discusses the mechanism and application of immune checkpoint blockade in mCRC treatment, and provides the latest research and clinical trial results.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2022)

Article Multidisciplinary Sciences

Development of a nanoparticle-based immunotherapy targeting PD-L1 and PLK1 for lung cancer treatment

Moataz Reda et al.

Summary: Immune checkpoint inhibitors have limited response rates in non-small cell lung cancer (NSCLC), and this study presents a nanoparticle-based immunotherapy that co-delivers a PLK1 inhibitor and PD-L1 antibody, showing anti-tumor immune responses in preclinical lung cancer models.

NATURE COMMUNICATIONS (2022)

Article Surgery

Primary squamous cell carcinoma of the colon: A rare case report

Hussein Nassar et al.

Summary: Squamous cell carcinoma (SCC) of the colon is a rare and aggressive type of colorectal cancer. Surgery remains the most important treatment option, while the role of chemotherapy and radiation therapy is still uncertain.

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS (2022)

Article Chemistry, Multidisciplinary

Development of Surface Chemical Strategies for Synthesizing Redox-Responsive Diatomite Nanoparticles as a Green Platform for On-Demand Intracellular Release of an Antisense Peptide Nucleic Acid Anticancer Agent

Monica Terracciano et al.

Summary: Redox-responsive silica drug delivery systems were synthesized using eco-friendly diatomite source to achieve on-demand release of peptide nucleic acid (PNA) in tumor reducing microenvironment, inhibiting immune check-point PD-1/PD-L1 in cancer cells. The systems showed safety and advantages in controlling and enhancing PNA release, paving the way for targeted immunotherapy.
Article Biochemistry & Molecular Biology

Relationship between VEGF Family Members, Their Receptors and Cell Death in the Neoplastic Transformation of Colorectal Cancer

Dominika Dakowicz et al.

Summary: Colorectal cancer is the second most common cause of cancer death globally. Both genetic and protein factors are involved in its pathogenesis. Researchers are exploring new diagnostic tools and potential therapeutic drugs, particularly VEGF family members related to blood vessel formation, which play a crucial role in colorectal cancer.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Review Biotechnology & Applied Microbiology

Engineering precision nanoparticles for drug delivery

Michael J. Mitchell et al.

Summary: The development of nanoparticles has shown promising clinical applications, overcoming the limitations of therapeutic interventions and biological barriers. Precision therapies have enhanced treatment efficacy through personalized interventions. Advancements in nanoparticle design aim to optimize drug delivery, improving efficacy in general applications and enabling tailored designs for precision applications.

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Biochemistry & Molecular Biology

Design of Gelatin-Capped Plasmonic-Diatomite Nanoparticles with Enhanced Galunisertib Loading Capacity for Drug Delivery Applications

Chiara Tramontano et al.

Summary: This study combined inorganic diatomite nanoparticles with gelatin-stabilized gold nanoparticles to develop an optical platform for drug delivery. By increasing the thickness of the gelatin shells, the drug loading capacity was improved. Optical modeling was used to monitor drug release processes and proved to be an efficient tool for designing polymer-coated nanocarriers.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nanoscience & Nanotechnology

Cancer Cell Membrane Camouflaged Mesoporous Silica Nanoparticles Combined with Immune Checkpoint Blockade for Regulating Tumor Microenvironment and Enhancing Antitumor Therapy

Peiqi Zhao et al.

Summary: The study introduces a biocompatible and tumor acidic environment responsive CCM-camouflaged mesoporous silica nanoparticle (CMSN) loaded with dacarbazine (DTIC) and combined with aPD1 for improved antitumor efficacy.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Medicine, General & Internal

Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review

Leah H. Biller et al.

Summary: Colorectal cancer is the third most common cause of cancer mortality worldwide. For patients diagnosed with metastatic colorectal cancer, approximately 70% to 75% can survive beyond 1 year. Tailoring treatments based on the molecular and pathologic features of the tumor has shown to improve overall survival rates.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Oncology

Activity of Sorafenib Plus Capecitabine in Previously Treated Metastatic Colorectal Cancer

Thomas J. George et al.

Summary: The study investigated the combination therapy of sorafenib and capecitabine in refractory metastatic colorectal cancer, showing a median progression-free survival of 6.2 months with manageable toxicity. This oral doublet therapy warrants further investigation for clinical use in patients with mCRC.

ONCOLOGIST (2021)

Article Oncology

Global colorectal cancer burden in 2020 and projections to 2040

Yue Xi et al.

Summary: Colorectal cancer is a major global public health challenge with higher incidence rates in developed countries and increasing trends in middle- and low-income countries. The rise of early-onset colorectal cancer is also seen. Increasing awareness, promoting healthy lifestyle choices, and implementing global screening programs are crucial in reducing the morbidity and mortality of colorectal cancer in the future.

TRANSLATIONAL ONCOLOGY (2021)

Article Multidisciplinary Sciences

Regulation of signal transduction pathways in colorectal cancer: implications for therapeutic resistance

Yeelon Yeoh et al.

Summary: Resistance to anti-cancer treatments is a critical health issue that can be caused by a variety of factors, including cancer cell properties and alterations in signaling pathways.
Article Immunology

SERS Sensing of Bacterial Endotoxin on Gold Nanoparticles

Alessandro Verde et al.

Summary: Engineered gold nanoparticles (AuNPs) are widely used in medicine but require accurate evaluation of safety, especially in detecting bacterial endotoxin contamination. Surface-enhanced Raman spectroscopy (SERS) is an efficient tool for the label-free identification and quantitative evaluation of endotoxin adsorbed on AuNP surfaces.

FRONTIERS IN IMMUNOLOGY (2021)

Review Oncology

Are All Anti-Angiogenic Drugs the Same in the Treatment of Second-Line Metastatic Colorectal Cancer? Expert Opinion on Clinical Practice

Eleonora Lai et al.

Summary: This review examines the use of angiogenesis-targeted therapies for the second-line management of metastatic colorectal cancer patients. The discussion focuses on mechanisms of resistance and anti-placental growth factor agents, highlighting the novel mechanism and efficacy of aflibercept.

FRONTIERS IN ONCOLOGY (2021)

Article Chemistry, Multidisciplinary

Synthesis of Chitosan/Diatomite Composite as an Advanced Delivery System for Ibuprofen Drug; Equilibrium Studies and the Release Profile

Sherouk M. Ibrahim et al.

Summary: The Chitosan/diatomite nanocomposite (CS/D) is a promising carrier for the ibuprofen drug due to its high loading capacity and controlled release rate. The loading of IB into CS/D is controlled by physical mechanisms, while the release of IB from CS/D is mainly influenced by complex diffusion and erosion mechanisms.

ACS OMEGA (2021)

Article Biochemistry & Molecular Biology

Diatom-like silica-protein nanocomposites for sustained drug delivery of ruthenium polypyridyl complexes

Hongdong Shi et al.

Summary: The study introduces a novel nanostructure using silica-coated human serum albumin nanoparticles for delivering ruthenium polypyridyl complexes into cells. By controlling the amount of silica coating, the release rate can be regulated, enhancing stability, drug uptake efficiency, and photodynamic therapy efficacy under light irradiation.

JOURNAL OF INORGANIC BIOCHEMISTRY (2021)

Article Chemistry, Multidisciplinary

SERS Quantification of Galunisertib Delivery in Colorectal Cancer Cells by Plasmonic-Assisted Diatomite Nanoparticles

Stefano Manago et al.

Summary: Galunisertib (LY2157299, LY), a small molecule, has multiple anticancer activities by blocking the transforming growth factor-beta 1 receptor and inhibiting the epithelial-to-mesenchymal transition (EMT) in colorectal cancer (CRC) cells. A hybrid nanosystem (DNP-AuNPs-LY@Gel) is proposed to deliver LY efficiently, reverse EMT in CRCs, and monitor drug release at the single-cell level using surface-enhanced Raman spectroscopy (SERS).
Review Biochemistry & Molecular Biology

Targeting TGFβ signal transduction for cancer therapy

Sijia Liu et al.

Summary: TGF beta family members are cytokines with diverse effects on cell fate regulation during development and tissue homeostasis. Dysregulation of TGF beta signaling can lead to developmental disorders and diseases, including cancer. TGF beta plays a dichotomous role in cancer progression, acting as a tumor suppressor in early stages and a tumor promoter in late stages, with effects on proliferation, differentiation, apoptosis, metastasis, and the tumor microenvironment.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

Article Chemistry, Multidisciplinary

Mesoporous Silica Nanoparticles for Drug Delivery

Miguel Manzano et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Review Biochemistry & Molecular Biology

Tumor angiogenesis: causes, consequences, challenges and opportunities

Roberta Lugano et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Review Cell Biology

PD-1/PD-L1-dependent immune response in colorectal cancer

Zahra Payandeh et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Review Chemistry, Medicinal

Anticancer Compounds Derived from Marine Diatoms

Hanaa Ali Hussein et al.

MARINE DRUGS (2020)

Article Chemistry, Multidisciplinary

Delivering the power of nanomedicine to patients today

Matthieu Germain et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Chemistry, Multidisciplinary

Nanostructured Biosilica of Diatoms: From Water World to Biomedical Applications

Chiara Tramontano et al.

APPLIED SCIENCES-BASEL (2020)

Review Nanoscience & Nanotechnology

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

Jonas G. Croissant et al.

NATURE REVIEWS MATERIALS (2020)

Review Pharmacology & Pharmacy

Small interfering RNA for cancer treatment: overcoming hurdles in delivery

Nitin Bharat Charbe et al.

ACTA PHARMACEUTICA SINICA B (2020)

Review Chemistry, Medicinal

Overcoming Barriers for siRNA Therapeutics: From Bench to Bedside

Muhammad Imran Sajid et al.

PHARMACEUTICALS (2020)

Review Computer Science, Interdisciplinary Applications

Potential applications of peptide nucleic acid in biomedical domain

Kshitij R. B. Singh et al.

ENGINEERING REPORTS (2020)

Review Engineering, Environmental

Mesoporous silica nanoparticles: Synthesis, pharmaceutical applications, biodistribution, and biosafety assessment

Fatemeh Farjadian et al.

CHEMICAL ENGINEERING JOURNAL (2019)

Article Oncology

FOLFOX and FOLFIRI Use in Stage IV Colon Cancer: Analysis of SEER-Medicare Data

Alfred I. Neugut et al.

CLINICAL COLORECTAL CANCER (2019)

Article Pharmacology & Pharmacy

Nanomedicines: The magic bullets reaching their target?

Beat Fluehmann et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

Review Oncology

Systemic treatment for metastatic colorectal cancer in the era of precision medicine

Jaideep Sandhu et al.

JOURNAL OF SURGICAL ONCOLOGY (2019)

Article Materials Science, Biomaterials

Surface engineered Amphora subtropica frustules using chitosan as a drug delivery platform for anticancer therapy

Rajendran Sasirekha et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2019)

Article Urology & Nephrology

A Critical Insight into the Clinical Translation of PD-1/PD-L1 Blockade Therapy in Clear Cell Renal Cell Carcinoma

Caroline E. Nunes-Xavier et al.

CURRENT UROLOGY REPORTS (2019)

Article Materials Science, Biomaterials

Chitosan sulfate inhibits angiogenesis via blocking the VEGF/VEGFR2 pathway and suppresses tumor growth in vivo

Yingying Li et al.

BIOMATERIALS SCIENCE (2019)

Review Pharmacology & Pharmacy

Regorafenib: A Review in Metastatic Colorectal Cancer

Sohita Dhillon

Review Pathology

Epithelial Mesenchymal Transition in Tumor Metastasis

Vivek Mittal

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 13 (2018)

Article Nanoscience & Nanotechnology

Gold decorated porous biosilica nanodevices for advanced medicine

Monica Terracciano et al.

NANOTECHNOLOGY (2018)

Review Oncology

Unraveling the Role of Angiogenesis in Cancer Ecosystems

Iratxe Zuazo-Gaztelu et al.

FRONTIERS IN ONCOLOGY (2018)

Article Chemistry, Inorganic & Nuclear

Slow-targeted release of a ruthenium anticancer agent from vitamin B12 functionalized marine diatom microalgae

Joachim Delasoie et al.

DALTON TRANSACTIONS (2018)

Article Engineering, Biomedical

Synthetic vs Natural: Diatoms Bioderived Porous Materials for the Next Generation of Healthcare Nanodevices

Ilaria Rea et al.

ADVANCED HEALTHCARE MATERIALS (2017)

Review Oncology

Antiangiogenic therapy for refractory colorectal cancer: current options and future strategies

Rachel Riechelmann et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2017)

Review Oncology

Cancer nanomedicine: a review of recent success in drug delivery

Stephanie Tran et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2017)

Article Chemistry, Multidisciplinary

Hollow Silica as an Optically Transparent and Thermally Insulating Polymer Additive

Lusi Ernawati et al.

LANGMUIR (2016)

Article Nanoscience & Nanotechnology

Nanoparticle-based strategy for personalized B-cell lymphoma therapy

Nicola M. Martucci et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2016)

Article Chemistry, Multidisciplinary

Nanotechnology for delivery of peptide nucleic acids (PNAs)

Anisha Gupta et al.

JOURNAL OF CONTROLLED RELEASE (2016)

Review Oncology

Ramucirumab in metastatic colorectal cancer: evidence to date and place in therapy

Helena Verdaguer et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2016)

Review Oncology

Toxicity management of immunotherapy for patients with metastatic melanoma

Helena Linardou et al.

ANNALS OF TRANSLATIONAL MEDICINE (2016)

Review Pharmacology & Pharmacy

A Review of Clinical Translation of Inorganic Nanoparticles

Aaron C. Anselmo et al.

AAPS JOURNAL (2015)

Review Biochemistry & Molecular Biology

Human cancer immunotherapy with antibodies to the PD-1 and PD-L1 pathway

Kim C. Ohaegbulam et al.

TRENDS IN MOLECULAR MEDICINE (2015)

Article Multidisciplinary Sciences

Targeted drug delivery using genetically engineered diatom biosilica

Bahman Delalat et al.

NATURE COMMUNICATIONS (2015)

Review Pharmacology & Pharmacy

Nanomedicine Scale-up Technologies: Feasibilities and Challenges

Rishi Paliwal et al.

AAPS PHARMSCITECH (2014)

Article Biochemistry & Molecular Biology

Diatomite biosilica nanocarriers for siRNA transport inside cancer cells

Ilaria Rea et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)

Article Engineering, Biomedical

A Preclinical System Prototype for Focused Microwave Thermal Therapy of the Breast

John Stang et al.

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING (2012)

Editorial Material Multidisciplinary Sciences

Nanomaterials for Drug Delivery

Jeffrey A. Hubbell et al.

SCIENCE (2012)

Review Chemistry, Multidisciplinary

Nanomedicine-Challenge and Perspectives

Kristina Riehemann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

Review Cell Biology

TGF-beta signaling in vascular biology and dysfunction

Marie-Jose Goumans et al.

CELL RESEARCH (2009)

Article Pharmacology & Pharmacy

Mesalamine Suppresses the Expression of TC22, a Novel Tropomyosin Isoform Associated with Colonic Neoplasia

Koushik K. Das et al.

MOLECULAR PHARMACOLOGY (2009)

Article Critical Care Medicine

The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis

S Gelperina et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)

Review Biochemistry & Molecular Biology

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics

PY Lu et al.

TRENDS IN MOLECULAR MEDICINE (2005)

Review Pharmacology & Pharmacy

The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability

LMS Chan et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)

Review Oncology

Clinical development of gene therapy for colorectal cancer

D Kerr

NATURE REVIEWS CANCER (2003)

Review Oncology

5-Fluorouracil: Mechanisms of action and clinical strategies

DB Longley et al.

NATURE REVIEWS CANCER (2003)