期刊
MARINE BIOTECHNOLOGY
卷 25, 期 3, 页码 347-357出版社
SPRINGER
DOI: 10.1007/s10126-023-10211-w
关键词
MSTN; European sea bass; DNA sequencing; SNP
This study investigated MSTN polymorphisms in the European sea bass population reared in Turkey. Nine SNPs and two indels were identified in MSTN, and they were significantly associated with growth traits such as standard length, total weight, and fillet weight. Haplotype analysis also revealed potential associations between haplogroup 2 and all measured growth traits.
The myostatin (MSTN) gene, known as growth differentiation factor-8 (GDF-8), is a member of the transforming growth factor-beta (TGF-beta) superfamily and plays a specific inhibitory role during the critical phases of skeletal muscle mass development in vertebrates. This study was conducted to investigate MSTN polymorphisms in harvest size European sea bass reared in Turkey. Nine single nucleotide polymorphisms (SNPs) and two indels were identified in exons 1-3 of MSTN in the European sea bass population The associations between the g.16612A indel located in intron 1 and standard length were significant. The MSTN g.15252 T > A locus in intron 2 was significantly related to the total weight, fillet weight and standard length (P < 0.05). The relationship between the g.14873C > T locus in exon 3 of MSTN and standard height, head length, body length, pre-anal length, abdominal length, post-anal length and head width was significant (P < 0.05). According to the results of the haplotype analysis, two haplogroup and eight haplotype combinations were detected in the population. The haplogroup 2 had significant associations with all measured growth traits (P < 0.05). Thus, SNPs and haplotypes identified in this study could be useful for European sea bass breeding and marker-assisted selection.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据