Development and characterization of Morinda tinctoria incorporated electrospun PHBV fiber mat for wound healing application

Article Chemistry, Multidisciplinary

Antioxidant and cytoprotective properties of loganic acid isolated from seeds of Strychnos potatorum L. against heavy metal induced toxicity in PBMC model

Alagarsamy Abirami et al.

Summary: This study successfully isolated an active component loganic acid from S. potatorum seeds, which exhibited strong free radical scavenging activity and significant cyto-protective effect against heavy metal toxicity.

DRUG AND CHEMICAL TOXICOLOGY (2022)

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Article Plant Sciences

Synergistic effect of Aloe vera flower and Aloe gel on cutaneous wound healing targeting MFAP4 and its associated signaling pathway: In-vitro study

Sultana Razia et al.

Summary: This study investigates the synergistic effect of a mixture of Aloe vera flower and Aloe gel on cutaneous wound healing and reveals its molecular mechanism targeting microfibril-associated glycoprotein 4 (MFAP4) and its associated signaling pathway. The mixture enhances cell proliferation, migration, and ECM formation in normal human dermal fibroblast (NHDF) cells by increasing the expression of MFAP4. It also activates the ERK and AKT signaling pathways and slightly modifies the cell cycle. In addition, the mixture induces cell migration and suppresses inflammatory cytokines in HaCaT cells. The knockdown of MFAP4 highlights its crucial role in cutaneous wound healing.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

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Review Dermatology

The impact of resveratrol on skin wound healing, scarring, and aging

Andrzej Hecker et al.

Summary: Resveratrol is a powerful antioxidant that may aid in wound healing and prevent skin aging. Current research suggests that resveratrol could be a feasible treatment approach, but further studies are needed to confirm its effects.

INTERNATIONAL WOUND JOURNAL (2022)

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Article Multidisciplinary Sciences

Fabrication, characterization and in vitro evaluation of Melia dubia extract infused nanofibers for wound dressing

Sathish Kumar Karuppannan et al.

Summary: This study focuses on the fabrication and characterization of Melia dubia leaf extract incorporated polycaprolactone/gelatin electrospun nanofibers for wound dressing applications. The nanofibers exhibited smooth and ultra-fine morphology with enhanced mechanical properties after the incorporation of the leaf extract. The fabricated nanofibers showed antioxidant activity, sustained drug release, and effective antibacterial activity against various pathogens. The results also demonstrated the biocompatibility of the nanofibers with fibroblast cells, indicating their potential for wound healing.

JOURNAL OF KING SAUD UNIVERSITY SCIENCE (2022)

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Article Pharmacology & Pharmacy

Development and characterization of catechin-in-cyclodextrin-in-phospholipid liposome to eradicate MRSA-mediated surgical site infection: Investigation of their anti-infective efficacy through in vitro and in vivo studies

Simran Sinsinwar et al.

Summary: The study developed catechin-in-cyclodextrin-in-phospholipid liposome (CCPL) as a potential novel drug for treating MRSA-mediated surgical site infection (SSI). CCPL demonstrated higher water solubility and in vitro permeability, significant antibacterial activity, and healing effects. Therefore, CCPL may be considered a promising candidate for treating MRSA-induced SSI after clinical trials.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

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Review Polymer Science

A Review on Electrospun Nanofibers Based Advanced Applications: From Health Care to Energy Devices

Vundrala Sumedha Reddy et al.

Summary: Electrospun nanofiber technologies have been widely utilized in various fields for their superior structure and performance. This review article focuses on the recent advancements and challenges in the healthcare and energy devices fields, emphasizing the unique potential of nanofibers.

POLYMERS (2021)

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Article Biochemistry & Molecular Biology

Staphylococcus aureus impairs dermal fibroblast functions with deleterious effects on wound healing

Masaya Yokota et al.

Summary: The study revealed that Staphylococcus aureus affects dermal fibroblasts, leading to impaired tissue repair functions such as upregulation of pro-inflammatory cytokines and degradation of collagen. This impact is not limited to specific cell sources and affects key mechanisms of wound healing.

FASEB JOURNAL (2021)

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Article Microbiology

Anthraquinones as Potential Antibiofilm Agents Against Methicillin-Resistant Staphylococcus aureus

Zhi-Man Song et al.

Summary: This study evaluated anthraquinone compounds for antibacterial and antibiofilm activities against MRSA, leading to the discovery of potential antibiofilm agents, anthraquinone-2-carboxlic acid (6) and rhein (12). The structure-activity relationship analysis indicated that the hydroxyl group at the C-2 position played an important role in inhibiting biofilm formation, while the carboxyl group at the same position had great influence on antibacterial and biofilm eradication activities.

FRONTIERS IN MICROBIOLOGY (2021)

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Review Biotechnology & Applied Microbiology

Chronic Wound Healing by Amniotic Membrane: TGF-β and EGF Signaling Modulation in Re-epithelialization

Catalina Ruiz-Canada et al.

Summary: The application of amniotic membrane on chronic wounds has shown effectiveness in resetting wound healing, particularly in re-epithelialization. Amniotic membrane affects wound healing by modulating cell signaling pathways and growth factors. Additionally, it influences protein expression in epithelial cells, promoting the progression of re-epithelialization.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Proceedings Paper Materials Science, Multidisciplinary

Preparation and characterization of Terminalia bellerica loaded PCL nanofibrous mats for biomedical applications

Rajalakshmi Ramamoorthy et al.

Summary: The study focuses on incorporating Terminalia bellerica into PCL nanofibrous mats, which showed that increasing the concentration of Terminalia led to enhanced fiber diameter, wettability, and water uptake properties, as well as antimicrobial activity against gram-negative bacteria. This makes Terminalia-loaded PCL mats a potential candidate for wound dressing applications.

MATERIALS TODAY-PROCEEDINGS (2021)

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Review Pharmacology & Pharmacy

Medicinal plants and their components for wound healing applications

Akshay Sharma et al.

Summary: This review article lists medicinal plants effective in wound treatment and systematically discusses plant constituent-based wound dressings, including patented formulations by different inventors. The compiled data aims to update researchers on the importance of plant-based components for wound treatment and management.

FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES (2021)

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Review Plant Sciences

A review of the antimicrobial potential of herbal drugs used in popular Italian medicine (1850s-1950s) to treat bacterial skin diseases

Rosalucia Mazzei et al.

JOURNAL OF ETHNOPHARMACOLOGY (2020)

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Article Plant Sciences

In vitro studies on antioxidant and cyto-protective activities of polyphenol-rich fraction isolated from Mangifera indica leaf

Kannan Nivedha et al.

SOUTH AFRICAN JOURNAL OF BOTANY (2020)

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Review Biochemistry & Molecular Biology

The Role of IL-6 in Skin Fibrosis and Cutaneous Wound Healing

Blair Z. Johnson et al.

BIOMEDICINES (2020)

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Article Materials Science, Multidisciplinary

Facile biofabrication of silver nanoparticles using Salvia officinalis leaf extract and its catalytic activity towards Congo red dye degradation

Shroog Shdied Royji Albeladi et al.

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T (2020)

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Article Biochemistry & Molecular Biology

Wound dressing based on electrospun PVA/chitosan/starch nanofibrous mats: Fabrication, antibacterial and cytocompatibility evaluation and in vitro healing assay

Hassan Adeli et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

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Review Integrative & Complementary Medicine

Wound Healing and the Use of Medicinal Plants

Aleksandra Shedoeva et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2019)

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Article Integrative & Complementary Medicine

In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis

Katyakyini Muniandy et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

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Article Biochemical Research Methods

Extraction of total phenolic content from Azadirachta indica or (neem) leaves: Kinetics study

Sandeep Shewale et al.

PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY (2018)

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Review Polymer Science

Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate): Enhancement Strategies for Advanced Applications

Ariagna L. Rivera-Briso et al.

POLYMERS (2018)

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Article Materials Science, Multidisciplinary

Nano-formulated curcumin accelerates acute wound healing through Dkk-1-mediated fibroblast mobilization and MCP-1-mediated anti-inflammation

Xinyi Dai et al.

NPG ASIA MATERIALS (2017)

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Article Orthopedics

Surgical Wound Classification and Surgical Site Infections in the Orthopaedic Patient

Ikemefuna Onyekwelu et al.

JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS GLOBAL RESEARCH AND REVIEWS (2017)

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Article Polymer Science

Morphological characterization and thermal properties of compatibilized poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)/poly(butylene succinate) (PBS)/halloysite ternary nanocomposites

Salima Kennouche et al.

EUROPEAN POLYMER JOURNAL (2016)

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Article Materials Science, Biomaterials

Antibacterial performance and in vivo diabetic wound healing of curcumin loaded gum tragacanth/poly(ε-caprolactone) electrospun nanofibers

Marziyeh Ranjbar-Mohammadi et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2016)

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Article Pharmacology & Pharmacy

Total phenolic content and antioxidant activity of morinda tinctoria leaves

Umadevi Parimi et al.

INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2015)

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Article Pharmacology & Pharmacy

Curcumin as a double-edged sword for stem cells: dose, time and cell type-specific responses to curcumin

Fatemeh Attari et al.

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2015)

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Article Dermatology

Comparison of the effects of topical fusidic acid and rifamycin on wound healing in rats

Mehmet S. Gurel et al.

INTERNATIONAL WOUND JOURNAL (2015)

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Article Dermatology

Wound healing and the role of fibroblasts

Bainbridge P.

Journal of Wound Care (2014)

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Review Engineering, Biomedical

Advancement of wound care from grafts to bioengineered smart skin substitutes

Robin Augustine et al.

PROGRESS IN BIOMATERIALS (2014)

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Article Engineering, Biomedical

Tissue engineered plant extracts as nanofibrous wound dressing

Guorui Jin et al.

BIOMATERIALS (2013)

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Article Polymer Science

Fabrication of highly porous PMMA electrospun fibers and their application in the removal of phenol and iodine

Hyun-Su Bae et al.

JOURNAL OF POLYMER RESEARCH (2013)

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Article Biochemistry & Molecular Biology

Synthesis and Structure-Activity Relationships of Novel Amino/Nitro Substituted 3-Arylcoumarins as Antibacterial Agents

Maria J. Matos et al.

MOLECULES (2013)

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Review Chemistry, Medicinal

Coumarin: a potential nucleus for anti-inflammatory molecules

Yogita Bansal et al.

MEDICINAL CHEMISTRY RESEARCH (2013)

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Article Integrative & Complementary Medicine

Phenolic composition and in vitro activity of the Brazilian fruit tree Caryocar coriaceum Wittm.

Mariana K. A. Araruna et al.

EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE (2013)

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Article Engineering, Biomedical

Electrospun nanostructured chitosan-poly(vinyl alcohol) scaffolds: a biomimetic extracellular matrix as dermal substitute

Dhakshinamoorthy Sundaramurthi et al.

BIOMEDICAL MATERIALS (2012)

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Article Materials Science, Textiles

Electrospinning of PHBV/ZnO Membranes: Structure and Properties

Rounak Naphade et al.

FIBERS AND POLYMERS (2012)

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Article Polymer Science

Herbal Drug Incorporated Antibacterial Nanofibrous Mat Fabricated by Electrospinning: An Excellent Matrix For Wound Dressings

S. Suganya et al.

JOURNAL OF APPLIED POLYMER SCIENCE (2011)

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Review Dentistry, Oral Surgery & Medicine

Factors Affecting Wound Healing

S. Guo et al.

JOURNAL OF DENTAL RESEARCH (2010)

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Review Dermatology

Fusidic acid in dermatology: an updated review

Helmut Schoefer et al.

EUROPEAN JOURNAL OF DERMATOLOGY (2010)

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Article Medicine, General & Internal

Wounds - From Physiology to Wound Dressing

P. Kujath et al.

DEUTSCHES ARZTEBLATT INTERNATIONAL (2008)

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Review Multidisciplinary Sciences

Wound repair and regeneration

Geoffrey C. Gurtner et al.

NATURE (2008)

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Article Polymer Science

Electrospun cellulose acetate fiber mats containing asiaticoside or Centella asiatica crude extract and the release characteristics of asiaticoside

Orawan Suwantong et al.

POLYMER (2008)

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Article Engineering, Biomedical

Investigation of fibroblast and keratinocyte cell-scaffold interactions using a novel 3D cell culture system

T. Sun et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2007)

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Article Chemistry, Medicinal

Morinda pubescens J.E.!Smith (Morinda tinctoria Roxb.) fruit extract accelerates wound healing in rats

Narayanasamy Mathivanan et al.

JOURNAL OF MEDICINAL FOOD (2006)

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Article Dermatology

Mixture of sugar and povidone-iodine stimulates wound healing by activating keratinocytes and fibroblast functions

Hiroshi Nakao et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2006)

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Article Dermatology

Ointment is evenly spread on the skin, in contrast to creams and solutions

UI Ivens et al.

BRITISH JOURNAL OF DERMATOLOGY (2001)

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Development and characterization of Morinda tinctoria incorporated electrospun PHBV fiber mat for wound healing application

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