相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Antibodies to watch in 2022
Helene Kaplon et al.
MABS (2022)
Designing antibodies as therapeutics
Paul J. Carter et al.
CELL (2022)
Antibody variable region engineering for improving cancer immunotherapy
Hantao Lou et al.
CANCER COMMUNICATIONS (2022)
UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Eric F. Pettersen et al.
PROTEIN SCIENCE (2021)
A structure-based engineering approach to abrogate pre-existing antibody binding to biotherapeutics
Joanne Lin et al.
PLOS ONE (2021)
Investigation of pre-existing reactivity to biotherapeutics can uncover potential immunogenic epitopes and predict immunogenicity risk
Nicoletta Bivi et al.
MABS (2019)
An automated benchmarking platform for MHC class II binding prediction methods
Massimo Andreatta et al.
BIOINFORMATICS (2018)
Mitigation of Pre-existing Antibodies to a Biotherapeutic in Non-clinical Species When Establishing Anti-drug Antibody Assay Cutpoint
Seema C. Kumar et al.
AAPS JOURNAL (2017)
Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes
Willem J. J. Falkenburg et al.
JOURNAL OF IMMUNOLOGY (2017)
Novel multispecific heterodimeric antibody format allowing modular assembly of variable domain fragments
Timothy J. Egan et al.
MABS (2017)
Fully automated antibody structure prediction using BIOVIA tools: Validation study
Helen Kemmish et al.
PLOS ONE (2017)
An immunoinhibition approach to overcome the impact of pre-existing antibodies on cut point establishment for immunogenicity assessment of moxetumomab pasudotox
Amy K. Schneider et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2016)
Specificity of human anti-variable heavy (VH) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor- receptor 1
J. C. Cordy et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2015)
Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification
Massimo Andreatta et al.
IMMUNOGENETICS (2015)
Separation of mAbs molecular variants by analytical hydrophobic interaction chromatography HPLC Overview and applications
Mark Haverick et al.
MABS (2014)
Pre-Existing Biotherapeutic-Reactive Antibodies: Survey Results Within the American Association of Pharmaceutical Scientists
Li Xue et al.
AAPS JOURNAL (2013)
Systematic generation of buffer systems for pH gradient ion exchange chromatography and their application
Frieder Kroener et al.
JOURNAL OF CHROMATOGRAPHY A (2013)
Autoantibodies to Variable Heavy (VH) Chain Ig Sequences in Humans Impact the Safety and Clinical Pharmacology of a VH Domain Antibody Antagonist of TNF-α Receptor 1
M. C. Holland et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2013)
Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes
Jason Greenbaum et al.
IMMUNOGENETICS (2011)
Application of a High-Throughput Screening Procedure with PEG-Induced Precipitation to Compare Relative Protein Solubility During Formulation Development with IgG1 Monoclonal Antibodies
Todd J. Gibson et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Role of conformational sampling in computing mutation-induced changes in protein structure and stability
Elizabeth H. Kellogg et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
Molecular Determinants of T Cell Epitope Recognition to the Common Timothy Grass Allergen
Carla Oseroff et al.
JOURNAL OF IMMUNOLOGY (2010)
The immunogenicity of humanized and fully human antibodies Residual immunogenicity resides in the CDR regions
Fiona A. Harding et al.
MABS (2010)
CHARMM: The Biomolecular Simulation Program
B. R. Brooks et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Design of therapeutic proteins with enhanced stability
Naresh Chennamsetty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Biophysical properties of human antibody variable domains
S Ewert et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Yet another numbering scheme for immunoglobulin variable domains:: An automatic modeling and analysis tool
A Honegger et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)