☆ 4.7 Letter

Reply to the letter Anti-HBc level predicting virological relapse after stopping nucleos(t)ide analogue in chronic hepatitis B

LIVER INTERNATIONAL (2023)

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Letter Gastroenterology & Hepatology

Anti-HBc level predicting virological relapse after stopping nucleos(t)ide analogue in chronic hepatitis B

Chiuan-Bo Huang et al.

LIVER INTERNATIONAL (2023)

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Article Gastroenterology & Hepatology

Discontinuation of nucleot(s)ide analogue therapy in HBeAg-negative chronic hepatitis B: a meta-analysis

Samuel Anthony Lachlan Hall et al.

Summary: A meta-analysis was conducted on clinical outcomes after nucleot(s)ide analogue (NA) discontinuation for HBeAg-negative CHB patients, revealing that virological relapse is common but clinical relapse occurs in only one-third of patients at 12 months post-NA discontinuation. Discontinuation of NA therapy can lead to HBsAg clearance, with higher rates observed with longer follow-up periods.

GUT (2022)

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Article Gastroenterology & Hepatology

Low anti-HBc levels are associated with lower risk of virological relapse after nucleos(t)ide analogue cessation in HBe antigen-negative patients

Valerie Ohlendorf et al.

Summary: In HBeAg-negative patients, lower anti-HBc levels are associated with a significantly lower risk of relapse after nucleos(t)ide analogue cessation.

LIVER INTERNATIONAL (2022)

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Review Gastroenterology & Hepatology

Discontinuation of oral antivirals in chronic hepatitis B: A systematic review

George Papatheodoridis et al.

HEPATOLOGY (2016)

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