期刊
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
卷 78, 期 -, 页码 S94-S100出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/gerona/glad028
关键词
Age-related skeletal muscle dysfunction; Function-promoting therapies; Mobility-disability; Sarcopenia; Skeletal muscle function deficit
Functional limitations and physical disabilities caused by aging and chronic diseases are significant issues that require the expedited development of function-promoting therapies. Collaboration among stakeholders is necessary to address this complex public health problem.
Background Functional limitations and physical disabilities associated with aging and chronic disease are major concerns for human societies and expeditious development of function-promoting therapies is a public health priority. Methods Expert panel discussion. Results The remarkable success of Operation Warp Speed for the rapid development of COVID-19 vaccines, COVID-19 therapeutics, and of oncology drug development programs over the past decade have taught us that complex public health problems such as the development of function-promoting therapies will require collaboration among many stakeholders, including academic investigators, the National Institutes of Health, professional societies, patients and patient advocacy organizations, the pharmaceutical and biotechnology industry, and the U.S. Food and Drug Administration. Conclusions There was agreement that the success of well designed, adequately powered clinical trials will require careful definitions of indication/s, study population, and patient-important endpoints that can be reliably measured using validated instruments, commensurate resource allocation, and versatile organizational structures such as those used in Operation Warp Speed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据