Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (vol 20, 580, 2022)

Summary: This study found that muscle sodium content in patients with ME/CFS was higher than in healthy controls before and after exercise. Furthermore, there was an inverse correlation between muscle sodium content and handgrip strength. These findings suggest that sodium overload may play a role in the pathophysiology of ME/CFS and could be a potential therapeutic target.