European Epidemiology of Pleural Mesothelioma-Real-Life Data From a Joint Analysis of the Mesoscape Database of the European Thoracic Oncology Platform and the European Society of Thoracic Surgery Mesothelioma Database

Article Pathology

Expression of phosphorylated ribosomal protein S6 in mesothelioma patients - correlation with clinico-pathological characteristics and outcome: results from the European Thoracic Oncology Platform (ETOP) Mesoscape project

Jan Hendrik Rueschoff et al.

Summary: Pleural mesothelioma (PM) is a aggressive malignancy with poor prognosis. Low phosphorylated S6 (pS6) immunoreactivity is significantly correlated with longer progression-free survival (PFS) and overall survival (OS) in PM patients. In this study, high pS6 expression is associated with lower likelihood of complete resection and shorter OS and PFS in non-epithelioid PM patients.

MODERN PATHOLOGY (2022)

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Article Medicine, General & Internal

First-line nivolumab plus ipilimumab in unresectable malignant pleural mesothelioma (CheckMate 743): a multicentre, randomised, open-label, phase 3 trial

Paul Baas et al.

Summary: Nivolumab plus ipilimumab demonstrated significant improvement in overall survival compared to standard chemotherapy for unresectable malignant pleural mesothelioma. This first-in-class treatment regimen has been approved for previously untreated patients in the USA and showed promising outcomes with manageable adverse events.

LANCET (2021)

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Review Oncology

Application of immunohistochemistry in diagnosis and management of malignant mesothelioma

David B. Chapel et al.

TRANSLATIONAL LUNG CANCER RESEARCH (2020)

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Article Cardiac & Cardiovascular Systems

ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma

Isabelle Opitz et al.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY (2020)

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Article Oncology

Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline

Hedy L. Kindler et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

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Article Public, Environmental & Occupational Health

Estimation of the global burden of mesothelioma deaths from incomplete national mortality data

Chimed-Ochir Odgerel et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2017)

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Article Multidisciplinary Sciences

Determinants of Survival in Malignant Pleural Mesothelioma: A Surveillance, Epidemiology, and End Results (SEER) Study of 14,228 Patients

Emanuela Taioli et al.

PLOS ONE (2015)

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Review Respiratory System

Malignant pleural mesothelioma: history, controversy and future of a manmade epidemic

Oluf Dimitri Roe et al.

EUROPEAN RESPIRATORY REVIEW (2015)

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Article Oncology

Initial Analysis of the International Association For the Study of Lung Cancer Mesothelioma Database

Valerie W. Rusch et al.

JOURNAL OF THORACIC ONCOLOGY (2012)

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Article Public, Environmental & Occupational Health

Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008

Vanya Delgermaa et al.

BULLETIN OF THE WORLD HEALTH ORGANIZATION (2011)

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Article Oncology

Novel marker D240, combined with calretinin, CEA, and TTF-1 - An optimal set of immunodiagnostic markers for pleural mesothelioma

Takeshi Mimura et al.

CANCER (2007)

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Article Pathology

Expression of phosphorylated ribosomal protein S6 in mesothelioma patients-correlation with clinico-pathological characteristics and outcome: results from the European Thoracic Oncology Platform (ETOP) Mesoscape project

Jan Hendrik Rueschoff et al.

Summary: Low phosphorylated S6 expression in non-epithelioid pleural mesothelioma patients is associated with shorter overall survival and progression-free survival, suggesting potential for future targeted treatment strategies.

MODERN PATHOLOGY

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European Epidemiology of Pleural Mesothelioma-Real-Life Data From a Joint Analysis of the Mesoscape Database of the European Thoracic Oncology Platform and the European Society of Thoracic Surgery Mesothelioma Database

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