期刊
JOURNAL OF TROPICAL PEDIATRICS
卷 62, 期 2, 页码 86-93出版社
OXFORD UNIV PRESS
DOI: 10.1093/tropej/fmv077
关键词
Kawasaki disease; coronary artery abnormalities; factors; east China
资金
- Chinese Natural Science Foundation [81370217, 81400222, 81570455]
- Jiangsu Province Science Foundation [BE2013632, BRA2015489, BK20150291]
- Suzhou Science and Technology Bureau [SZS201411]
Background: Because of the different genetic backgrounds, living environments and economic conditions, the epidemiologic, clinical characteristics and risk factors for coronary artery abnormalities (CAAs) in the Chinese population may differ among different parts of China. Methods: We did a retrospective study to explore the clinical characteristics and risk factors for CAAs in east China between 2006 and 2014. Results: There were 1016 patients during the study period. Of the 1004 patients who completed echocardiographic studies, 23.9% had CAAs. Sex, serum albumin, erythrocyte sedimentation rate (ESR), Mycoplasma pneumoniae (MP) infection, intravenous immunoglobulin (IVIG) started after the 10th day of illness and IVIG non-responders were independent risk factors associated with CAA. Conclusions: East China has a lower incidence of CAAs compared with southwest and northeast China, while similar to north China. Male gender, serum albumin, ESR, MP infection, IVIG started after the 10th day of illness and IVIG non-responders were predictive of CAA.
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