Efficacy of Antithrombotic Therapy and Risk of Hemorrhagic Complication in Blunt Cerebrovascular Injury Patients with Concomitant Injury: A Systematic Review

Article Clinical Neurology

Aspirin does not affect hematoma growth in severe spontaneous intracranial hematoma

Junhua Yang et al.

Summary: This study found that prior ASA use does not increase the incidence of HG in severe ICH patients, while high blood pressure at admission is a risk factor for HG.

NEUROSURGICAL REVIEW (2022)

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Article Clinical Neurology

Between Scylla and Charybdis: risks of early therapeutic anticoagulation for venous thromboembolism after acute intracranial hemorrhage

Thuhien Nguyen et al.

Summary: This study aims to assess the risk of hematoma expansion in patients with acute intracranial hemorrhage (ICH) who require therapeutic anticoagulation for venous thromboembolism. The retrospective study included 50 patients and found that 12% of them developed hematoma expansion during the treatment, with a mortality rate of 4%.

BRITISH JOURNAL OF NEUROSURGERY (2022)

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Article Clinical Neurology

Anticoagulation after intracerebral hemorrhage in patients with atrial fibrillation: between Scylla and Charybdis

Carla Seabra Abrantes et al.

Summary: In patients with AF and previous ICH, anticoagulation with OAC can reduce thrombotic events and overall mortality without a significant increase in bleeding risk. Factors such as ICH score and higher CHA(2)DS(2)-VASc were associated with higher mortality.

NEUROLOGICAL SCIENCES (2022)

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Article Emergency Medicine

Blunt cerebrovascular injury: incidence and long-term follow-up

Dennis Hundersmarck et al.

Summary: This study identified the incidence of blunt cerebrovascular injuries in BCVI patients and revealed significant functional impairment in long-term follow-up among BCVI patients. Antiplatelet therapy showed a significant effect on reducing the in-hospital stroke rate.

EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY (2021)

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Review Critical Care Medicine

Antithrombotic choice in blunt cerebrovascular injuries: Experience at a tertiary trauma center, systematic review, and meta-analysis

Jerry C. Ku et al.

Summary: The study compared the risk-benefit profile of antiplatelet (AP) versus anticoagulant (AC) therapy in blunt cerebrovascular injuries (BCVIs) patients. Results showed that the hemorrhage rate was lower in the AP treatment group compared to the AC treatment group, but there was no significant difference in the rate of ischemic stroke between the two treatment groups.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2021)

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Review Medicine, General & Internal

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

Matthew J. Page et al.

Summary: The PRISMA statement was designed to help systematic reviewers transparently report the purpose, methods, and findings of their reviews. The updated PRISMA 2020 statement includes new reporting guidance, a 27-item checklist, an abstract checklist, and revised flow diagrams for reviews.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Clinical Neurology

Treatment strategies for patients with concurrent blunt cerebrovascular and traumatic brain injury

Javier M. Figueroa et al.

Summary: For patients with both traumatic brain injury (TBI) and blunt cerebrovascular injuries (BCVI), a treatment paradigm should be developed to weigh the risk and benefits of therapies based on the severity of intracranial hemorrhages (ICH) and stroke prevention, with close monitoring allowing for the safe use of anti-platelet/anticoagulant therapy to prevent strokes.

JOURNAL OF CLINICAL NEUROSCIENCE (2021)

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Review Critical Care Medicine

Treatment of asymptomatic blunt cerebrovascular injury (BCVI): a systematic review

Patrick B. Murphy et al.

Summary: This systematic review on the management of asymptomatic BCVI found that any medical management was better than no treatment, but no specific differences were found. Vessel healing was rare and mostly occurred following low-grade injuries.

TRAUMA SURGERY & ACUTE CARE OPEN (2021)

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Article Clinical Neurology

Management of Extracranial Blunt Cerebrovascular Injuries: Experience with an Aspirin-Based Approach

Joshua S. Catapano et al.

WORLD NEUROSURGERY (2020)

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Review Critical Care Medicine

Anticoagulant chemoprophylaxis in patients with traumatic brain injuries: A systematic review

Paul J. Spano et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2020)

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Review Clinical Neurology

y Ischemic Stroke due to Blunt Traumatic Cerebrovascular Injury

Mark R. Harrigan

STROKE (2020)

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Article Clinical Neurology

Occurrence and prognostic effect of cervical spine injuries and cervical artery injuries with concomitant severe head injury

Juho Vehvilainen et al.

ACTA NEUROCHIRURGICA (2020)

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Article Critical Care Medicine

Evaluation and management of blunt cerebrovascular injury: A practice management guideline from the Eastern Association for the Surgery of Trauma

Dennis Y. Kim et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2020)

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Article Critical Care Medicine

Updated guidelines to reduce venous thromboembolism in trauma patients: A Western Trauma Association critical decisions algorithm

Eric J. Ley et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2020)

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Article Critical Care Medicine

Blunt cerebrovascular injury: The case for universal screening

Stefan W. Leichtle et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2020)

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Review Critical Care Medicine

Evolution of non-operative management of liver trauma

Adam Brooks et al.

TRAUMA SURGERY & ACUTE CARE OPEN (2020)

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Article Surgery

Early Chemical Thromboprophylaxis Does not Increase the Risk of Intracranial Hematoma Progression in Patients with Isolated Severe Traumatic Brain Injury

Philipp Stoermann et al.

WORLD JOURNAL OF SURGERY (2019)

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Review Clinical Neurology

A Systematic Review of the Risks and Benefits of Venous Thromboembolism Prophylaxis in Traumatic Brain Injury

Joseph Margolick et al.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2018)

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Article Critical Care Medicine

Management of blunt cerebrovascular injury (BCVI) in the multisystem injury patient with contraindications to immediate anti-thrombotic therapy

Michelle K. McNutt et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2018)

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Article Critical Care Medicine

Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries

Clay Cothren Burlew et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2018)

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Article Critical Care Medicine

Time to stroke: A Western Trauma Association multicenter study of blunt cerebrovascular injuries

Clay Cothren Burlew et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2018)

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Review Emergency Medicine

Best practice guidelines for blunt cerebrovascular injury (BCVI)

Tor Brommeland et al.

SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE (2018)

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Article Clinical Neurology

Blunt cerebrovascular injuries in severe traumatic brain injury: incidence, risk factors, and evolution

Pierre Esnault et al.

JOURNAL OF NEUROSURGERY (2017)

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Article Clinical Neurology

Use of anti-platelet agents after traumatic intracranial hemorrhage

Keith Kerr et al.

CLINICAL NEUROLOGY AND NEUROSURGERY (2016)

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Article Surgery

Timing of Pharmacologic Venous Thromboembolism Prophylaxis in Severe Traumatic Brain Injury: A Propensity-Matched Cohort Study

James P. Byrne et al.

JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS (2016)

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Article Critical Care Medicine

Early antithrombotic therapy is safe and effective in patients with blunt cerebrovascular injury and solid organ injury or traumatic brain injury

Charles P. Shahan et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2016)

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Article Critical Care Medicine

Early antithrombotic therapy is safe and effective in patients with blunt cerebrovascular injury and solid organ injury or traumatic brain injury

Charles P. Shahan et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2016)

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Article Clinical Neurology

Clinical and radiographic outcomes following traumatic Grade 1 and 2 carotid artery injuries: a 10-year retrospective analysis from a Level I trauma center. The Parkland Carotid and Vertebral Artery Injury Survey

William W. Scott et al.

JOURNAL OF NEUROSURGERY (2015)

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Article Clinical Neurology

Early Pharmacological Venous Thromboembolism Prophylaxis Is Safe After Operative Fixation of Traumatic Spine Fractures

Dennis Yong Kim et al.

SPINE (2015)

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Article Critical Care Medicine

Blunt cerebrovascular injury screening guidelines: What are we willing to miss?

Brandon Robert Bruns et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2014)

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Article Critical Care Medicine

Blunt cerebrovascular injury screening with 64-channel multidetector computed tomography: More slices finally cut it

Elena M. Paulus et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2014)

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Article Critical Care Medicine

A randomized, double-blinded, placebo-controlled pilot trial of anticoagulation in low-risk traumatic brain injury: The Delayed Versus Early Enoxaparin Prophylaxis I (DEEP I) study

Herb A. Phelan et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2012)

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Article Critical Care Medicine

Blunt cerebrovascular injuries: Redefining screening criteria in the era of noninvasive diagnosis

Clay Cothren Burlew et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2012)

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Article Critical Care Medicine

Early treatment of blunt cerebrovascular injury with concomitant hemorrhagic neurologic injury is safe and effective

Rachael A. Callcut et al.

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY (2012)

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Review Critical Care Medicine

Acute Pharmacological DVT Prophylaxis after Spinal Cord Injury

Sean Christie et al.

JOURNAL OF NEUROTRAUMA (2011)

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Article Clinical Neurology

Cerebrovascular Dissections: A Review. Part II: Blunt Cerebrovascular Injury

Matthew R. Fusco et al.

NEUROSURGERY (2011)

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Article Emergency Medicine

Management of blunt extracranial traumatic cerebrovascular injury: a multidisciplinary survey of current practice

Mark R. Harrigan et al.

WORLD JOURNAL OF EMERGENCY SURGERY (2011)

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Article Surgery

Management of the Most Severely Injured Spleen A Multicenter Study of the Research Consortium of New England Centers for Trauma (ReCONECT)

George C. Velmahos et al.

ARCHIVES OF SURGERY (2010)

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Article Critical Care Medicine

The epidemiology of BCVI at a single state trauma centre

Peter Y. K. Hwang et al.

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED (2010)

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Article Surgery

Postdischarge Outcomes of Blunt Cerebrovascular Injuries

Randall W. Franz et al.

VASCULAR AND ENDOVASCULAR SURGERY (2010)

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Article Surgery

Treatment for Blunt Cerebrovascular Injuries Equivalence of Anticoagulation and Antiplatelet Agents

C. Clay Cothren et al.

ARCHIVES OF SURGERY (2009)

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Article Surgery

Anticoagulation is the gold standard therapy for blunt carotid injuries to reduce stroke rate

CC Cothren et al.

ARCHIVES OF SURGERY (2004)

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Article Surgery

Prospective screening for blunt cerebrovascular injuries - Analysis of diagnostic modalities and outcomes

PR Miller et al.

ANNALS OF SURGERY (2002)

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Article Critical Care Medicine

Blunt vascular neck injuries: Diagnosis and outcomes of extracranial vessel injury

EC McKevitt et al.

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE (2002)

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Article Surgery

Treatment-related outcomes from blunt cerebrovascular injuries - Importance of routine follow-up arteriography

WL Biffl et al.

ANNALS OF SURGERY (2002)

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Efficacy of Antithrombotic Therapy and Risk of Hemorrhagic Complication in Blunt Cerebrovascular Injury Patients with Concomitant Injury: A Systematic Review

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