4.8 Article

Sigma-Bond Metathesis as an Unusual Asymmetric Induction Step in Rhodium-Catalyzed Enantiodivergent Synthesis of C-N Axially Chiral Biaryls

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Rhodium-Catalyzed Atroposelective Access to Axially Chiral Olefins via C-H Bond Activation and Directing Group Migration

Ruijie Mi et al.

Summary: Axially chiral acyclic olefins were synthesized via C-H activation and olefin coupling with the assistance of a migratable directing group. Experimental results suggest different reaction pathways were utilized during the directing group migration process.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Review Chemistry, Multidisciplinary

Asymmetric Synthesis of Axially Chiral C-N Atropisomers

Patricia Rodriguez-Salamanca et al.

Summary: This review provides an overview of various methodologies for the asymmetric synthesis of axially chiral C-N atropisomers, and discusses their background, preparation methods, and applications.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

Article Chemistry, Organic

Transition-Metal-, Additive-, and Solvent-Free [3+3] Annulation of RCF2-Imidoyl Sulfoxonium Ylides with Cyclopropenones to Give Multifunctionalized CF3-Pyridones

Si Wen et al.

Summary: An efficient strategy was developed to synthesize 1,3,4-triaryl-6-trifluoromethylpyridones in good yields from CF3-imidoyl sulfoxonium ylides and cyclopropenones. The reaction proceeded under transition-metal-, additive-, and solvent-free conditions, generating dimethyl sulfoxide as byproduct and tolerating various functional groups.

JOURNAL OF ORGANIC CHEMISTRY (2022)

Article Chemistry, Organic

Asymmetric Synthesis of Hydroquinazolines Bearing C4-Tetrasubstituted Stereocenters via Kinetic Resolution of α-Tertiary Amines

Qianwen Jiang et al.

Summary: A novel protocol for asymmetric synthesis of hydroquinazolines with C4-tetrasubstituted stereocenters has been developed, involving kinetic resolution of 2-amido alpha-tertiary benzylamines using chiral phosphoric acid catalyzed intramolecular dehydrative cyclizations. This method provides access to both alpha-tertiary benzylamines and hydroquinazolines with high enantioselectivities and broad scope. An intriguing restricted rotation of the C-N bond was observed for hydroquinazoline products bearing C4-tetrasubstituted stereocenters.

ORGANIC LETTERS (2022)

Article Chemistry, Organic

Mechanism and Origins of Enantioselectivity of Cobalt-Catalyzed Intermolecular Hydroarylation/Cyclization of 1,6-Enynes with N-Pyridylindoles

Deping Kong et al.

Summary: Density functional theory calculations were used to investigate the cobalt-catalyzed intermolecular hydro-arylation/cyclization reaction. The computations revealed that the reaction proceeds through an oxidative cyclization of 1,6-enynes, followed by metal-assisted sigma-bond metathesis/reductive elimination, leading to the final hydroarylation/cyclization product. The steric repulsion and pi···pi interaction were found to be crucial in determining the observed enantioselectivity.

JOURNAL OF ORGANIC CHEMISTRY (2022)

Article Chemistry, Organic

Rhodium(III)-Catalyzed Atroposelective Synthesis of C-N Axially Chiral Naphthylamines and Variants via C-H Activation

Peiyuan Wang et al.

Summary: In this study, an efficient and atroposelective method for constructing C-N atropisomers was reported. By utilizing rhodium(III)-catalyzed C-H activation of sulfoxonium ylides in [4+2] annulation with sterically hindered, electron-rich alkynes, C-N axially chiral 4-functionalized 1-naphthols were synthesized with high regio- and enantioselectivity.

ORGANIC LETTERS (2022)

Review Chemistry, Multidisciplinary

Atropisomers beyond the C-C axial chirality: Advances in catalytic asymmetric synthesis

Guang-Jian Mei et al.

Summary: Atropisomers beyond the C-C axis have become important additions to the field of axially chiral compounds. Previously considered challenging, these atropisomers characterized by C-N, C-O, C-B, or N-N bonds have been found to possess stable axially chiral frameworks due to their shorter bond lengths and electron-repelling effects. Recent years have seen rapid progress in this emerging area, with various catalytic approaches being reported for their efficient synthesis. These X-Y axially chiral compounds are valuable molecules that can be utilized as ligands or catalysts in asymmetric catalysis or evaluated for their potential biological activities. The chemistry of atropisomers beyond C-C axial chirality is believed to hold an important position in organic chemistry and beyond.
Article Chemistry, Multidisciplinary

Single-Step Synthesis of Atropisomers with Vicinal C-C and C-N Diaxes by Cobalt-Catalyzed Atroposelective C-H Annulation

Bing-Jie Wang et al.

Summary: We have developed a single-step method for constructing atropisomers with vicinal chiral axes, achieving good stereocontrol. The produced products exhibit circular polarized luminescence properties and are suitable for potential applications.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

Article Chemistry, Organic

Ruthenium-Catalyzed Hydroxyl-Directed peri-Selective C-H Activation and Annulation of 1-Naphthols with CF3-Imidoyl Sulfoxonium Ylides for the Synthesis of 2-(Trifluoromethyl)-2,3-dihydrobenzo[de]chromen-2-amines

Zuguang Yang et al.

Summary: A novel ruthenium-catalyzed method using hydroxyl as a directing group has been developed for the selective C-H activation and annulation of 1-naphthols with CF3-substituted imidoyl sulfoxonium ylides. This strategy provides a facile and efficient route to diverse trifluoromethyl-containing 2,3-dihydrobenzo[de]chromen-2-amines, with notable advantages including readily available materials, excellent regioselectivity, good functional group compatibility, and scalability.

ORGANIC LETTERS (2022)

Article Chemistry, Organic

Formal [4+1] Annulation of Azoalkenes with CF3-Imidoyl Sulfoxonium Ylides and Dual Double Bond Isomerization Cascade: Synthesis of Trifluoromethyl-Containing Pyrazole Derivatives

Yue Sun et al.

Summary: A straightforward strategy for the metal-free construction of trifluoromethyl-containing pyrazole derivatives has been achieved. The protocol features mild conditions, easy operation, excellent substrate compatibility, and good regioselectivity. The utility of this method is demonstrated through scale-up reaction and further elaboration of the obtained pyrazole products.

ORGANIC LETTERS (2022)

Review Chemistry, Multidisciplinary

Stereoselective construction of atropisomers featuring a C-N chiral axis

Yong-Jie Wu et al.

Summary: This article comprehensively summarizes the research progress of atropisomeric C-N compounds, with a focus on their synthetic strategies, and provides insights into future advancements.

GREEN SYNTHESIS AND CATALYSIS (2022)

Review Chemistry, Multidisciplinary

Chiral Cyclopentadienyl Ligands: Design, Syntheses, and Applications in Asymmetric Catalysis

Josep Mas-Rosello et al.

Summary: The development of new chiral ligands is crucial for stereocontrol in metal-catalyzed reactions, especially with the increasing demand for bioactive molecules as single enantiomers. The successful application of Cp-X ligands in metal-catalyzed transformations allows access to valuable chiral molecules, with critical comparisons of existing ligand families and discussion of future research directions for further enhancing their performance and application in enantioselective catalysis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Chiral Pd-Catalyzed Enantioselective Syntheses of Various N-C Axially Chiral Compounds and Their Synthetic Applications

Osamu Kitagawa

Summary: Biaryl atropisomers, as key structural components in various compounds, have been recently studied for their catalytic asymmetric syntheses and applications in asymmetric reactions. Previously overlooked, these compounds have now become a popular research area in synthetic organic chemistry, with successful applications in various synthetic reactions.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

Article Chemistry, Multidisciplinary

Rhodium-Catalyzed Atroposelective Construction of Indoles via C-H Bond Activation

Lincong Sun et al.

Summary: This study reports the rhodium(III)-catalyzed C-H activation of anilines bearing an N-isoquinolyl directing group for oxidative [3+2] annulation with four classes of internal alkynes, leading to atroposelective indole synthesis via dynamic kinetic annulation with C-N reductive elimination constituting the stereo-determining step. The reaction proceeds under mild conditions with high regio- and enantioselectivity and functional group compatibility.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Organic

Ruthenium-Catalyzed Chemoselective N-H Bond Insertion Reactions of 2-Pyridones/7-Azaindoles with Sulfoxonium Ylides

Xiaofeng Liu et al.

Summary: A ruthenium-catalyzed highly chemoselective N-alkylation of 2-pyridones has been developed, providing N-alkylated 2-pyridone derivatives in good yields and excellent N-selectivity. The key to this unprecedented reaction is the use of CpRu(PPh3)(2)Cl as the catalyst and sulfoxonium ylides as the alkylation reagents, which can also be applied to 7-azaindoles with slight variations in reaction conditions. Furthermore, sulfonium ylides are also suitable alkylation reagents for good selectivity in N-alkylation of 2-pyridones.

ORGANIC LETTERS (2021)

Article Chemistry, Multidisciplinary

Catalytic and Enantioselective Control of the C-N Stereogenic Axis via the Pictet-Spengler Reaction

Ahreum Kim et al.

Summary: A novel chiral phosphoric acid-catalyzed atroposelective Pictet-Spengler reaction of N-arylindoles has been reported, resulting in highly enantioenriched N-aryl-tetrahydro-beta-carbolines with axial chirality. The introduction of a hydrogen bond donor on the bottom aromatic ring, forming a secondary interaction with the phosphoryl oxygen, is crucial for achieving high enantioselectivity. The transformation is tolerant to a wide variety of substituents and can provide products with up to 98% ee.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

N-Heterocyclic Carbene-Catalyzed Atroposelective Annulation for Access to Thiazine Derivatives with C-N Axial Chirality

Tingting Li et al.

Summary: A catalytic atroposelective cycloaddition reaction between thioureas and ynals has been developed, enabling the establishment of C-N axial chirality with excellent optical purities. The resulting axially chiral thiazine derivative products contain multiple functional groups and are suitable for further transformations.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

Jun Kee Cheng et al.

Summary: Atropisomerism is a stereochemical behavior exhibited by three-dimensional molecules with rotationally restricted sigma bonds, and compounds with atropisomerically chiral properties are increasingly utilized in fields where molecular asymmetry is influential. There is a steady demand for atroposelective synthesis, leading to conceptually novel and streamlined methods for expanding the structural diversity of atropisomers. This review summarizes key achievements in the stereoselective preparation of biaryl, heterobiaryl, and nonbiaryl atropisomers between 2015 and 2020, emphasizing synthetic strategies for each structural class and potential applications of atropochiral targets.

CHEMICAL REVIEWS (2021)

Article Chemistry, Organic

Peri-Selective Direct Acylmethylation and Amidation of Naphthalene Derivatives Using Iridium and Rhodium Catalysts

Chandrababu Naidu Kona et al.

Summary: The study describes iridium-catalyzed acylmethylation and rhodium-catalyzed amidation of naphthalene derivatives using sulfoxonium ylides and dioxazolones as carbene and nitrene transfer agents. The use of an SMe group as a directing group is crucial for achieving peri-selective functionalization, which can be easily removed or transformed after the catalysis into other synthetically useful functionalities.

SYNTHESIS-STUTTGART (2021)

Article Chemistry, Multidisciplinary

An axial-to-axial chirality transfer strategy for atroposelective construction of C-N axial chirality

Ze-Shui Liu et al.

Summary: A general and efficient method for accessing C-N atropisomers through an axial-to-axial chirality transfer strategy based on palladium/chiral norbornene cooperative catalysis has been developed. The obtained C-N axial chirality originates from the preformed transient C-C axial chirality with high fidelity, allowing for the synthesis of a variety of C-N axially chiral phenanthridinones in excellent enantioselectivities. This method can be applied for the construction of two stereogenic axes via double atroposelective C-H arylation or further transformation of the products via axial-to-axial diastereoinduction.
Article Chemistry, Multidisciplinary

Enantioselective Synthesis of Atropisomeric Biaryls by Pd-Catalyzed Asymmetric Buchwald-Hartwig Amination

Peng Zhang et al.

Summary: In this study, a Pd-catalyzed cross-coupling strategy was employed for the synthesis of N-C axially chiral biaryl molecules with excellent enantioselectivities and good yields. The practicality of this reaction was demonstrated in the synthesis of biologically relevant molecules.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Nitrosobenzene-Enabled Chiral Phosphoric Acid Catalyzed Enantioselective Construction of Atropisomeric N-Arylbenzimidazoles

Qian-Jin An et al.

Summary: This study presents a strategy for the synthesis of axially chiral N-arylbenzimidazoles using chiral phosphoric acid catalysis, demonstrating excellent chemo- and regioselectivity as well as high levels of enantiocontrol. The nitroso group plays a unique role in the domino reaction, acting as a linchpin to facilitate C-N bond formation and oxidative aromatization. The resulting atropisomeric products can be further elaborated to produce axially chiral derivatives for potential applications in asymmetric catalysis.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Synthesis of Atropisomers by Transition-Metal-Catalyzed Asymmetric C-H Functionalization Reactions

Chen-Xu Liu et al.

Summary: Transition-metal-catalyzed enantioselective C-H functionalization is an efficient atom-economic strategy for the synthesis of atropisomers, with a focus on asymmetric catalysis via Pd, Rh, and Ir complexes.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Organic

Annulation of CF3-Imidoyl Sulfoxonium Ylides with 1,3-Dicarbonyl Compounds: Access to 1,2,3-Trisubstituted 5-Trifluoromethylpyrroles

Si Wen et al.

Summary: A lithium-bromide-promoted nucleophilic substitution/annulation cascade reaction has been developed for the synthesis of 1,2,3-trisubstituted 5-trifluoromethylpyrroles from CF3-imidoyl sulfoxonium ylides and 1,3-dicarbonyl compounds, yielding products in 27-78% yield. The reaction exhibits a broad substrate scope and produces dimethyl sulfoxide and water as byproducts.

ORGANIC LETTERS (2021)

Article Chemistry, Organic

α-Imino Iridium Carbenes from Imidoyl Sulfoxonium Ylides: Application in the One-Step Synthesis of Indoles

Clarice A. D. Caiuby et al.

JOURNAL OF ORGANIC CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis

Chen-Xi Ye et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Chemistry, Multidisciplinary

Transition Metal-Catalyzed Enantioselective C-H Functionalization via Chiral Transient Directing Group Strategies

Gang Liao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Chiral Bicyclo[2.2.2]octane-Fused CpRh Complexes: Synthesis and Potential Use in Asymmetric C-H Activation

Guozhu Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Time-dependent enantiodivergent synthesis via sequential kinetic resolution

Hang-Fei Tu et al.

NATURE CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Enantioselective Synthesis of C-N Axially Chiral N-Aryloxindoles by Asymmetric Rhodium-Catalyzed Dual C-H Activation

Honghe Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Disparate Catalytic Scaffolds for Atroposelective Cyclodehydration

Yongseok Kwon et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Chemistry, Multidisciplinary

Accessing Remote meta- and para-C(sp(2))-H Bonds with Covalently Attached Directing Groups

Aniruddha Dey et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

π-Bond Character in Metal-Alkyl Compounds for C-H Activation: How, When, and Why?

Christopher P. Gordon et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Chemistry, Multidisciplinary

Construction of Axially Chiral Compounds via Asymmetric Organocatalysis

Yong-Bin Wang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

Article Chemistry, Multidisciplinary

Solvent-Dependent Asymmetric Synthesis of Alkynyl and Monofluoroalkenyl Isoindolinones by CpRhIII-Catalyzed C-H Activation

Teng Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Organic

Rhodium(III)-Catalyzed Redox-Neutral Synthesis of Isoquinolinium Salts via C-H Activation of Imines

Miaomiao Tian et al.

JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Chemistry, Organic

Highly Efficient Syntheses of C-N Axially Chiral 1-(ortho-hydroxyaryl)uracil using a Chiral Auxiliary and a Chiral Base

Futoshi Hasegawa et al.

ASIAN JOURNAL OF ORGANIC CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors

Gang Shan et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Enantiodivergent Desymmetrization in the Rhodium( III)-Catalyzed Annulation of Sulfoximines with Diazo Compounds

Bingxue Shen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Multidisciplinary

Transition-Metal-Catalyzed C-H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds

Joshua R. Hummel et al.

CHEMICAL REVIEWS (2017)

Article Chemistry, Multidisciplinary

Highly Atroposelective Synthesis of Arylpyrroles by Catalytic Asymmetric Paal-Knorr Reaction

Lei Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Chemistry, Multidisciplinary

Hexafluoroisopropanol as a highly versatile solvent

Ignacio Colomer et al.

NATURE REVIEWS CHEMISTRY (2017)

Review Chemistry, Multidisciplinary

Catalytic Enantioselective Synthesis of MarilineA and Related Isoindolinones through a Biomimetic Approach

Chang Min et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Experimental and Computational Exploration of para-Selective Silylation with a Hydrogen-Bonded Template

Arun Maji et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Cross-Coupling of α-Carbonyl Sulfoxonium Ylides with C-H Bonds

Manuel Barday et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Organic

Catalytic Enantioselective Synthesis of N-C Axially Chiral Phenanthridin-6-one Derivatives

Tomoaki Hirata et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

Review Chemistry, Multidisciplinary

A Simple and Versatile Amide Directing Group for C-H Functionalizations

Ru-Yi Zhu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Overcoming the Limitations of C-H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis

Hui Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Cyclization of N-Methoxy Benzamides with Alkynes using an Internal Oxidant through C-H/N-O Bond Activation

Ganesan Sivakumar et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Article Multidisciplinary Sciences

Discovery and enantiocontrol of axially chiral urazoles via organocatalytic tyrosine click reaction

Ji-Wei Zhang et al.

NATURE COMMUNICATIONS (2016)

Review Chemistry, Multidisciplinary

Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes

Guoyong Song et al.

ACCOUNTS OF CHEMICAL RESEARCH (2015)

Review Chemistry, Multidisciplinary

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C-H Functionalizations

Baihua Ye et al.

ACCOUNTS OF CHEMICAL RESEARCH (2015)

Article Chemistry, Multidisciplinary

Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation

Zhi-Jia Fang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Organic

Synthesis of a C-N Axially Chiral N-Arylisatin through Asymmetric Intramolecular N-Arylation

Atsuo Nakazaki et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination

Matthew E. Diener et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Multidisciplinary

Chiral Cp-Rhodium(III)-Catalyzed Asymmetric Hydroarylations of 1,1-Disubstituted Alkenes

Baihua Ye et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation**

Achim Link et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Asymmetric Synthesis of Isoindolones by Chiral Cyclopentadienyl-Rhodium(III)-Catalyzed C-H Functionalizations

Baihua Ye et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Rh(III)-Catalyzed intramolecular redox-neutral cyclization of alkenes via C-H activation

Zhuangzhi Shi et al.

CHEMICAL COMMUNICATIONS (2014)

Article Chemistry, Multidisciplinary

Enantioselective C-H Bond Addition of Pyridines to Alkenes Catalyzed by Chiral Half-Sandwich Rare-Earth Complexes

Guoyong Song et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Multidisciplinary

Rh(III)- and Ir(III)-Catalyzed C-H Alkynylation of Arenes under Chelation Assistance

Fang Xie et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Multidisciplinary

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C-H Allylations of Benzamides

Baihua Ye et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Chemistry, Multidisciplinary

Room-Temperature Synthesis of Trisubstituted Allenylsilanes via Regioselective C-H Functionalization

Rong Zeng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Chemistry, Multidisciplinary

Rh(III)-Catalyzed Synthesis of Multisubstituted Isoquinoline and Pyridine N-Oxides from Oximes and Diazo Compounds

Zhuangzhi Shi et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Chemistry, Multidisciplinary

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

Gerhard Bringmann et al.

CHEMICAL REVIEWS (2011)

Article Chemistry, Multidisciplinary

Rh(III)-Catalyzed Directed C-H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile

Souvik Rakshit et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Organic

Ruthenium-Catalyzed C-H/N-O Bond Functionalization: Green Isoquinolone Syntheses in Water

Lutz Ackermann et al.

ORGANIC LETTERS (2011)

Article Chemistry, Multidisciplinary

Solvent-Dependent Enantiodivergent Mannich-Type Reaction: Utilizing a Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Yoshihiro Sohtome et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Catalytic Enantioselective Synthesis of Atropisomeric Indoles with an N-C Chiral Axis

Nobutaka Ototake et al.

CHEMISTRY-A EUROPEAN JOURNAL (2010)

Article Chemistry, Multidisciplinary

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N-O Bond as a Handle for C-N Bond Formation and Catalyst Turnover

Nicolas Guimond et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Chemistry, Multidisciplinary

Pd(II)-Catalyzed Olefination of sp3 C-H Bonds

Masayuki Wasa et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Review Chemistry, Multidisciplinary

Total synthesis of chiral biaryl natural products by asymmetric biaryl coupling

Marisa C. Kozlowski et al.

CHEMICAL SOCIETY REVIEWS (2009)

Article Chemistry, Organic

Stereochemical control of both C-C and C-N axial chirality in the synthesis of chiral N,O-biaryls

Jossian Oppenheimer et al.

ORGANIC LETTERS (2007)

Review Chemistry, Multidisciplinary

The sigma-CAM mechanism: sigma complexes as the basis of sigma-bond metathesis at late-transition-metal centers

Robin N. Perutz et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Article Chemistry, Multidisciplinary

Efficient synthesis of optically active atropisomeric anilides through catalytic asymmetric N-arylation reaction

O Kitagawa et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Review Chemistry, Multidisciplinary

Atroposelective synthesis of axially chiral biaryl compounds

G Bringmann et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)

Article Chemistry, Multidisciplinary

Direct catalytic asymmetric aldol additions of methyl ynones. Spontaneous reversal in the sense of enantioinduction

BM Trost et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)