4.6 Letter

Association of herpes zoster with COVID-19 vaccination: A systematic review and meta-analysis

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Article Pharmacology & Pharmacy

Association study between herpes zoster reporting and mRNA COVID-19 vaccines (BNT162b2 and mRNA-1273)

Laure-Helene Preta et al.

Summary: There is an increased risk of herpes zoster (HZ) following mRNA COVID-19 vaccination, especially among older individuals. Data from the worldwide pharmacovigilance database show a significantly higher reporting of HZ with mRNA COVID-19 vaccines compared to influenza vaccines. The risk of reporting HZ is reduced among individuals under 40 years old compared to older individuals.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2022)

Article Immunology

Reactivation of Varicella Zoster Virus after Vaccination for SARS-CoV-2

Mina Psichogiou et al.

Summary: Seven immunocompetent patients over the age of 50 presented with herpes zoster infection within a median of 9 days (range 7-20) after receiving the COVID-19 vaccine. The occurrence of herpes zoster within 1-21 days after vaccination and the involvement of T cell-mediated immunity suggest that COVID-19 vaccination may be a probable cause of herpes zoster. These cases highlight the need for ongoing assessment of vaccine safety during the massive COVID-19 vaccination campaign and emphasize the importance of reporting and communicating any vaccination-associated adverse events.

VACCINES (2021)