The Calixcorrole

We recently reported that DDQ-mediated oxidative coupling of pyrrole to a free-base meso-triarylcorrole in dichloromethane at room temperature results in the near-instantaneous formation of pyrrole-appended isocorroles. Herein we report that the use of refluxing dichloromethane and longer reaction times result in the oxidative addition of a second molecule of pyrrole, affording a novel isoporphyrinoid macrocycle-calixcorrole - in up to 47% yield.

Automated summary

We recently discovered that by using refluxing dichloromethane and extending reaction times, a second molecule of pyrrole can be oxidatively added, resulting in the formation of a novel isoporphyrinoid macrocycle-calixcorrole with yields up to 47%.