4.5 Article

Crystallization of Amorphous Nifedipine Under Isothermal Conditions: Inter-laboratory Reproducibility and Investigation of the Factors Affecting Reproducibility

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Influence of the crystallization tendencies of pharmaceutical glasses on the applicability of the Adam-Gibbs-Vogel and Vogel-Tammann-Fulcher equations in the prediction of their long-term physical stability

Katsutoshi Yamaguchi et al.

Summary: Amorphization is an effective method to improve the solubility and bioavailability of poorly watersoluble compounds. However, it can lead to chemical and physical instability. This study found a correlation between the physical stability of amorphous compounds and molecular mobility, providing a more accurate prediction for long-term physical stability.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)

Review Pharmacology & Pharmacy

Recent Advances in Enhancement of Dissolution and Supersaturation of Poorly Water-Soluble Drug in Amorphous Pharmaceutical Solids: A Review

Qin Shi et al.

Summary: The article reviews recent advancements in the dissolution and supersaturation of amorphous formulations, highlighting the crucial roles of stabilizing agents. Maintaining supersaturation in solution is identified as a key factor for enhancing drug dissolution and oral bioavailability.

AAPS PHARMSCITECH (2021)

Review Pharmacology & Pharmacy

Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

Sonal V. Bhujbal et al.

Summary: This review provides an updated overview of manufacturing techniques for preparing amorphous solid dispersions (ASDs). It discusses the impact of formulation, equipment, and process variables on the physical stability of ASDs, and proposes selection strategies to aid in developing ASDs with satisfactory physical stability.

ACTA PHARMACEUTICA SINICA B (2021)

Article Pharmacology & Pharmacy

Structure and Glass Transition Temperature of Amorphous Dispersions of Model Pharmaceuticals with Nucleobases from Molecular Dynamics

Ctirad Cervinka et al.

Summary: This study uses molecular dynamics simulations to predict the glass transition temperatures of active pharmaceutical ingredients mixed with excipients, providing insights for more efficient formulation design in the future.

PHARMACEUTICS (2021)

Review Pharmacology & Pharmacy

Recent Technologies for Amorphization of Poorly Water-Soluble Drugs

Do-Hyun Kim et al.

Summary: Amorphization technology is a focus in the pharmaceutical industry to enhance the solubility and bioavailability of drugs. Traditional carriers for amorphous drugs have limitations, leading to the investigation of novel carriers and preparation methods to improve drug loading and amorphization. Recent advancements in amorphization technologies, such as co-amorphous systems and mesoporous particle-based techniques, are discussed for their characteristics and commercial potential.

PHARMACEUTICS (2021)

Article Chemistry, Medicinal

Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs

Michael D. Shultz

JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Pharmacology & Pharmacy

Biorelevant dissolution testing of a weak base: Interlaboratory reproducibility and investigation of parameters controlling in vitro precipitation

Philippe Berben et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Review Pharmacology & Pharmacy

Effects of the Preparation Process on the Properties of Amorphous Solid Dispersions

Siyuan Huang et al.

AAPS PHARMSCITECH (2018)

Review Pharmacology & Pharmacy

Amorphous and Crystalline Particulates: Challenges and Perspectives in Drug Delivery

Hisham Al-Obaidi et al.

CURRENT PHARMACEUTICAL DESIGN (2017)

Article Pharmacology & Pharmacy

Glass-forming ability of compounds in marketed amorphous drug products

Nicole Wyttenbach et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2017)

Article Medicine, Research & Experimental

Relaxation Dynamics vs Crystallization Kinetics in the Amorphous State: The Case of Stiripentol

Guadalupe N. Ruiz et al.

MOLECULAR PHARMACEUTICS (2017)

Review Chemistry, Multidisciplinary

The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Khadijah Edueng et al.

PHARMACEUTICAL RESEARCH (2017)

Article Pharmacology & Pharmacy

The effect of structurally related impurities on crystallinity reduction of sulfamethazine by grinding

Yoshito Hamada et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)

Article Medicine, Research & Experimental

Correlation between Molecular Mobility and Physical Stability in Pharmaceutical Glasses

Mehak Mehta et al.

MOLECULAR PHARMACEUTICS (2016)

Article Medicine, Research & Experimental

Molecular Dynamics and Physical Stability of Coamorphous Ezetimib and Indapamide Mixtures

J. Knapik et al.

MOLECULAR PHARMACEUTICS (2015)

Review Pharmacology & Pharmacy

Insoluble drug delivery strategies: review of recent advances and business prospects

Sandeep Kalepu et al.

ACTA PHARMACEUTICA SINICA B (2015)

Article Medicine, Research & Experimental

Mechanism of Amorphous Itraconazole Stabilization in Polymer Solid Dispersions: Role of Molecular Mobility

Sunny P. Bhardwaj et al.

MOLECULAR PHARMACEUTICS (2014)

Article Chemistry, Multidisciplinary

Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments

Bernard Van Eerdenbrugh et al.

PHARMACEUTICAL RESEARCH (2014)

Review Pharmacology & Pharmacy

Biopharmaceutical classification of poorly soluble drugs with respect to enabling formulations

Stephen Timothy Buckley et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)

Article Medicine, Research & Experimental

Correlation between Molecular Mobility and Physical Stability of Amorphous Itraconazole

Sunny P. Bhardwaj et al.

MOLECULAR PHARMACEUTICS (2013)

Review Pharmacology & Pharmacy

Evaluation of amorphous solid dispersion properties using thermal analysis techniques

Jared A. Baird et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Article Chemistry, Medicinal

Understanding the glass-forming ability of active pharmaceutical ingredients for designing supersaturating dosage forms

Kohsaku Kawakami et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2012)

Article Medicine, Research & Experimental

Molecular Mobility as an Effective Predictor of the Physical Stability of Amorphous Trehalose

Sunny P. Bhardwaj et al.

MOLECULAR PHARMACEUTICS (2012)

Article Chemistry, Multidisciplinary

A Practical Method to Predict Physical Stability of Amorphous Solid Dispersions

Stephanie Greco et al.

PHARMACEUTICAL RESEARCH (2012)

Article Pharmacology & Pharmacy

Differences in crystallization rate of nitrendipine enantiomers in amorphous solid dispersions with HPMC and HPMCP

Tamaki Miyazaki et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2011)

Article Chemistry, Medicinal

Towards Effective Solid Form Screening

Morten Alleso et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Article Chemistry, Medicinal

A Classification System to Assess the Crystallization Tendency of Organic Molecules from Undercooled Melts

Jared A. Baird et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2010)

Review Pharmacology & Pharmacy

Pharmaceutical applications of cyclodextrins: basic science and product development

Thorsteinn Loftsson et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2010)

Article Pharmacology & Pharmacy

Correlating thermodynamic and kinetic parameters with amorphous stability

Kirsten A. Graeser et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

Review Chemistry, Medicinal

Local Mobility in Amorphous Pharmaceuticals-Characterization and Implications on Stability

Sisir Bhattacharya et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

Review Chemistry, Medicinal

Role of thermodynamic, molecular, and kinetic factors in crystallization from the amorphous state

Chandan Bhugra et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2008)

Article Medicine, Research & Experimental

Thermodynamics, Molecular Mobility and Crystallization Kinetics of Amorphous Griseofulvin

Deliang Zhou et al.

MOLECULAR PHARMACEUTICS (2008)

Article Pharmacology & Pharmacy

Crystallization rate of amorphous nifedipine analogues unrelated to the glass transition temperature

Tamaki Miyazaki et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2007)

Article Chemistry, Medicinal

Sudden rise of crystal growth rate of nifedipine near Tg without and with polyvinylpyrrolidone

Hajime Ishida et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2007)

Article Thermodynamics

Thermal methods for evaluating polymorphic transitions in nifedipine

D. Grooff et al.

THERMOCHIMICA ACTA (2007)

Article Chemistry, Multidisciplinary

A comparison of the physical stability of amorphous felodipine and nifedipine systems

Patrick J. Marsac et al.

PHARMACEUTICAL RESEARCH (2006)

Article Biochemistry & Molecular Biology

Glass transition and enthalpy relaxation of amorphous lactose glass

Md. Kamrul Haque et al.

CARBOHYDRATE RESEARCH (2006)

Article Medicine, Research & Experimental

Role of molecular interaction in stability of celecoxib-PVP amorphous systems

Piyush Gupta et al.

MOLECULAR PHARMACEUTICS (2005)

Article Chemistry, Medicinal

Crystallization kinetics of amorphous nifedipine studied by model-fitting and model-free approaches

DL Zhou et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2003)