4.5 Article

A quantitative approach to study the adaptation of rhythmic eye movements and the resulting tonic eye deviation in larval zebrafish

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Summary: A fundamental principle of biological motor control is that neural commands driving movement must conform to the response properties of motor plants. Recent observations in the oculomotor system have challenged classical formulations of both the oculomotor plant and the oculomotor integrator. This study uses measurements from larval zebrafish to link dynamics in the oculomotor plant to dynamics in the neural integrator, suggesting that leaky integration on multiple, distributed timescales may be a general feature of motor circuitry.

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