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Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
Taku Tsunekawa et al.
EBIOMEDICINE (2017)
Increased Indoleamine 2,3-Dioxygenase and Quinolinic Acid Expression in Microglia and Miller Cells of Diabetic Human and Rodent Retina
Ping Hu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility
Martin Valdearcos et al.
CELL METABOLISM (2017)
Study of retinal alterations in a high fat diet-induced type ii diabetes rodent: Meriones shawi
Imane Hammoum et al.
ACTA HISTOCHEMICA (2017)
Proteome analysis of retinal glia cells-related inflammatory cytokines in the aqueous humour of diabetic patients
Stela Vujosevic et al.
ACTA OPHTHALMOLOGICA (2016)
Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus
Juan Jose Ramos-Rodriguez et al.
MOLECULAR NEUROBIOLOGY (2016)
Diabetic ketoacidosis in juvenile rats is associated with reactive gliosis and activation of microglia in the hippocampus
Weei Lo et al.
PEDIATRIC DIABETES (2016)
High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia
Caroline Baufeld et al.
ACTA NEUROPATHOLOGICA (2016)
Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice
Ana I. Arroba et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity
Shuai Hao et al.
BRAIN BEHAVIOR AND IMMUNITY (2016)
Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice
Wilma Helena Oliveira et al.
BRAIN RESEARCH (2016)
Effect of Chinese herbal compound Naofucong on the inflammatory process induced by high glucose in BV-2 cells
Jing Guang-chan et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2016)
Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice
Montasir Elahi et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Blood-brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice
Alexis M. Stranahan et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
CX3CR1 deficiency accelerates the development of retinopathy in a rodent model of type 1 diabetes
Eleni Beli et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2016)
Anti-inflammatory role of sesamin in STZ induced mice model of diabetic retinopathy
Saif Ahmad et al.
JOURNAL OF NEUROIMMUNOLOGY (2016)
Exaggerated Increases in Microglia Proliferation, Brain Inflammatory Response and Sickness Behaviour upon Lipopolysaccharide Stimulation in Non-Obese Diabetic Mice
Barry McGuiness et al.
NEUROIMMUNOMODULATION (2016)
The effect of abscisic acid chronic treatment on neuroinflammatory markers and memory in a rat model of high-fat diet induced neuroinflammation
Sandra Sanchez-Sarasua et al.
NUTRITION & METABOLISM (2016)
Long-term central pathology and cognitive impairment are exacerbated in a mixed model of Alzheimer's disease and type 2 diabetes
Carmen Infante-Garcia et al.
PSYCHONEUROENDOCRINOLOGY (2016)
Juvenile exposure to a high fat diet promotes behavioral and limbic alterations in the absence of obesity
Angeles Vinuesa et al.
PSYCHONEUROENDOCRINOLOGY (2016)
pEPito-driven PEDF Expression Ameliorates Diabetic Retinopathy Hallmarks
Sofia M. Calado et al.
HUMAN GENE THERAPY METHODS (2016)
The DPP4 Inhibitor Linagliptin Protects from Experimental Diabetic Retinopathy
Nadine Dietrich et al.
PLOS ONE (2016)
Erianin inhibits high glucose-induced retinal angiogenesis via blocking ERK1/2-regulated HIF-1α-VEGF/VEGFR2 signaling pathway
Zengyang Yu et al.
SCIENTIFIC REPORTS (2016)
miR-124 Regulates Amadori-Glycated Albumin-Induced Retinal Microglial Activation and Inflammation by Targeting Rac1
Ning Dong et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2016)
Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice
Ping Hu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2015)
Disruption of Fractalkine Signaling Leads to Microglial Activation and Neuronal Damage in the Diabetic Retina
Sandra M. Cardona et al.
ASN NEURO (2015)
One-day high-fat diet induces inflammation in the nodose ganglion and hypothalamus of mice
T. M. Zaved Waise et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Enhancement of LPS-Induced Microglial Inflammation Response via TLR4 Under High Glucose Conditions
Xiang Zhang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
Enhanced endoplasmic reticulum stress in bone marrow angiogenic progenitor cells in a mouse model of long-term experimental type 2 diabetes
Maulasri Bhatta et al.
DIABETOLOGIA (2015)
Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice
Carmel M. McVicar et al.
DIABETOLOGIA (2015)
DHA Inhibited AGEs-Induced Retinal Microglia Activation Via Suppression of the PPARγ/NFκB Pathway and Reduction of Signal Transducers in the AGEs/RAGE Axis Recruitment into Lipid Rafts
Li Wang et al.
NEUROCHEMICAL RESEARCH (2015)
Melatonin Reduces Hypoglycemia-Induced Neuronal Death in Rats
Jin Hee Kim et al.
NEUROENDOCRINOLOGY (2015)
Treadmill exercise is associated with reduction of reactive microgliosis and pro-inflammatory cytokine levels in the hippocampus of type 2 diabetic rats
Dae Young Yoo et al.
NEUROLOGICAL RESEARCH (2015)
Recurrent hypoinsulinemic hyperglycemia in neonatal rats increases PARP-1 and NF-κB expression and leads to microglial activation in the cerebral cortex
Tate Gisslen et al.
PEDIATRIC RESEARCH (2015)
Obesity diminishes synaptic markers, alters microglial morphology, and impairs cognitive function
Miriam E. Bocarsly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease
Juan Jose Ramos-Rodriguez et al.
PSYCHONEUROENDOCRINOLOGY (2015)
ASK1 modulates the expression of microRNA Let7A in microglia under high glucose in vitro condition
Juhyun Song et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes
Qin Yang et al.
JOURNAL OF OPHTHALMOLOGY (2015)
MicroRNA-146b-3p Regulates Retinal Inflammation by Suppressing Adenosine Deaminase-2 in Diabetes
Sadanand Fulzele et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation
Judith M. van der Harg et al.
FRONTIERS IN NEUROSCIENCE (2015)
Protection by beta-Hydroxybutyric acid against insulin glycation, lipid peroxidation and microglial cell apoptosis
Manijheh Sabokdast et al.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Early spatiotemporal characterization of microglial activation in the retinas of rats with streptozotocin-induced diabetes
Xiaofei Chen et al.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2015)
High-Fat Diet Induces Toll-Like Receptor 4-Dependent Macrophage/Microglial Cell Activation and Retinal Impairment
Jong-Jer Lee et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)
CD74 indicates microglial activation in experimental diabetic retinopathy and exogenous methylglyoxal mimics the response in normoglycemic retina
Jing Wang et al.
ACTA DIABETOLOGICA (2014)
A cross talk between class a scavenger receptor and receptor for advanced glycation end-products contributes to diabetic retinopathy
Ke Ma et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Fractalkine (CX3CL1) Is Involved in the Early Activation of Hypothalamic Inflammation in Experimental Obesity
Joseane Morari et al.
DIABETES (2014)
CD40 promotes the development of early diabetic retinopathy in mice
Jose-Andres C. Portillo et al.
DIABETOLOGIA (2014)
Hormones and Diet, but Not Body Weight, Control Hypothalamic Microglial Activity
Yuanqing Gao et al.
GLIA (2014)
Evidence for Cortical Neuronal Loss in Male Type 2 Diabetic Goto-Kakizaki Rats
Shafaat Hussain et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Microglia are Selectively Activated in Endocrine and Cardiovascular Control Centres in Streptozotocin-Induced Diabetic Rats
I. Rana et al.
JOURNAL OF NEUROENDOCRINOLOGY (2014)
Glucocorticoid sensitization of microglia in a genetic mouse model of obesity and diabetes
Aditi Dey et al.
JOURNAL OF NEUROIMMUNOLOGY (2014)
Obesity Elicits Interleukin 1-Mediated Deficits in Hippocampal Synaptic Plasticity
Joanna R. Erion et al.
JOURNAL OF NEUROSCIENCE (2014)
Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin
Sarah Srodulski et al.
MOLECULAR NEURODEGENERATION (2014)
Activation of microglia and induction of pro-inflammatory cytokines in the hippocampus of type 2 diabetic rats
In Koo Hwang et al.
NEUROLOGICAL RESEARCH (2014)
Enriched environment induces beneficial effects on memory deficits and microglial activation in the hippocampus of type 1 diabetic rats
Francele Valente Piazza et al.
METABOLIC BRAIN DISEASE (2014)
Astrocytic and microglial response in experimentally induced diabetic rat brain
Aarti Nagayach et al.
METABOLIC BRAIN DISEASE (2014)
Chemokine Mediated Monocyte Trafficking into the Retina: Role of Inflammation in Alteration of the Blood-Retinal Barrier in Diabetic Retinopathy
Sampathkumar Rangasamy et al.
PLOS ONE (2014)
Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function
Martin Valdearcos et al.
CELL REPORTS (2014)
CNS Inflammation and Bone Marrow Neuropathy in Type 1 Diabetes
Ping Hu et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Potential roles of adenosine deaminase-2 in diabetic retinopathy
Nehal M. Elsherbiny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy
Nehal M. Elsherbiny et al.
LIFE SCIENCES (2013)
Neonatal Hyperglycemia Inhibits Angiogenesis and Induces Inflammation and Neuronal Degeneration in the Retina
Elsa Kermorvant-Duchemin et al.
PLOS ONE (2013)
Pyruvate Administration Reduces Recurrent/Moderate Hypoglycemia-Induced Cortical Neuron Death in Diabetic Rats
Bo Young Choi et al.
PLOS ONE (2013)
The Effects of Age and Cx3cr1 Deficiency on Retinal Microglia in the Ins2Akita Diabetic Mouse
Jelena Marie Kezic et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling
Zhen Wang et al.
BRITISH JOURNAL OF NUTRITION (2012)
Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration
Seok Joon Won et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Obesity is associated with hypothalamic injury in rodents and humans
Joshua P. Thaler et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
GLP-1 secretion by microglial cells and decreased CNS expression in obesity
Camilla Kappe et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats
Seok Joon Won et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Prevention of hypoglycemia-induced neuronal death by minocycline
Seok Joon Won et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Pigment Epithelium-Derived Factor (PEDF) Peptide Eye Drops Reduce Inflammation, Cell Death and Vascular Leakage in Diabetic Retinopathy in Ins2Akita Mice
Yanling Liu et al.
MOLECULAR MEDICINE (2012)
AGEs-RAGE mediated up-regulation of connexin43 in activated human microglial CHME-5 cells
Shamim B. Shaikh et al.
NEUROCHEMISTRY INTERNATIONAL (2012)
Exercise protects against high-fat diet-induced hypothalamic inflammation
Chun-Xia Yi et al.
PHYSIOLOGY & BEHAVIOR (2012)
Induction of Neuronal Death by Microglial AGE-Albumin: Implications for Alzheimer's Disease
Kyunghee Byun et al.
PLOS ONE (2012)
IL-1β Is Upregulated in the Diabetic Retina and Retinal Vessels: Cell-Specific Effect of High Glucose and IL-1β Autostimulation
Yang Liu et al.
PLOS ONE (2012)
Upregulation of Retinal Neuronal MCP-1 in the Rodent Model of Diabetic Retinopathy and Its Function In Vitro
Ning Dong et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
High glucose stimulates TNFα and MCP-1 expression in rat microglia via ROS and NF-κB pathways
Yi Quan et al.
ACTA PHARMACOLOGICA SINICA (2011)
A2A Adenosine Receptor (A2AAR) as a Therapeutic Target in Diabetic Retinopathy
Ahmed S. Ibrahim et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Microglia/Macrophages Migrate through Retinal Epithelium Barrier by a Transcellular Route in Diabetic Retinopathy Role of PKCζ in the Goto Kakizaki Rat Model
Samy Omri et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Macrophage colony-stimulating factor and its receptor signaling augment glycated albumin-induced retinal microglial inflammation in vitro
Wei Liu et al.
BMC CELL BIOLOGY (2011)
Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes
Ahmed S. Ibrahim et al.
DIABETES (2011)
Intervention With an Erythropoietin-Derived Peptide Protects Against Neuroglial and Vascular Degeneration During Diabetic Retinopathy
Carmel M. McVicar et al.
DIABETES (2011)
Comorbidities of Diabetes and Hypertension: Mechanisms and Approach to Target Organ Protection
Amanda N. Long et al.
JOURNAL OF CLINICAL HYPERTENSION (2011)
Central administration of interleukin-4 exacerbates hypothalamic inflammation and weight gain during high-fat feeding
Shinsuke Oh-I et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
High glucose enhances intracellular Ca2+ responses triggered by purinergic stimulation in retinal neurons and microglia
Tiago de Oliveira Simoes Pereira et al.
BRAIN RESEARCH (2010)
Animal Models in Diabetes and Pregnancy
Alicia Jawerbaum et al.
ENDOCRINE REVIEWS (2010)
Changes in Melanocortin Expression and Inflammatory Pathways in Fetal Offspring of Nonhuman Primates Fed a High-Fat Diet
B. E. Grayson et al.
ENDOCRINOLOGY (2010)
Enduring consequences of maternal obesity for brain inflammation and behavior of offspring
Staci D. Bilbo et al.
FASEB JOURNAL (2010)
Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats
Gina Y. Tsai et al.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2009)
Expression of Macrophage Colony-Stimulating Factor (M-CSF) and Its Receptor in Streptozotocin-Induced Diabetic Rats
Wei Liu et al.
CURRENT EYE RESEARCH (2009)
Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity
Marciane Milanski et al.
JOURNAL OF NEUROSCIENCE (2009)
Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet
Christy L. White et al.
NEUROBIOLOGY OF DISEASE (2009)
NAD(P)H Oxidase-Dependent Regulation of CCL2 Production during Retinal Inflammation
Wenbo Zhang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Baicalein Reduces Inflammatory Process in a Rodent Model of Diabetic Retinopathy
Li-ping Yang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2009)
Microglial activation in human diabetic retinopathy
Hui-yang Zeng et al.
ARCHIVES OF OPHTHALMOLOGY (2008)
Sinomenine inhibits activation of rat retinal microglia induced by advanced glycation end products
Ai Ling Wang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2007)
High glucose stimulates GRO secretion from rat microglia via ROS, PKC, and NF-κB pathways
Yi Quan et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
AGEs mediated expression and secretion of TNF alpha in rail retinal microglia
Ai Ling Wang et al.
EXPERIMENTAL EYE RESEARCH (2007)
Microglial changes occur without neural cell death in diabetic retinopathy
David Gaucher et al.
VISION RESEARCH (2007)
The physiology of obese-hyperglycemic mice [ob/ob mice]
Per Lindstrom
THESCIENTIFICWORLDJOURNAL (2007)
Induction of reactive oxygen species and cell survival in the presence of advanced glycation end products and similar structures
Annett Schmitt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2006)
Degradation of glycated bovine serum albumin in microglial cells
A Stolzing et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
The Ins2Akita mouse as a model of early retinal complications in diabetes
AJ Barber et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy
JK Krady et al.
DIABETES (2005)
Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus
SW Suh et al.
DIABETES (2005)
Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus
JP Klein et al.
NEUROBIOLOGY OF DISEASE (2004)
Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina
EJ Kuiper et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2004)
Neuronal and glial response in the rat hypothalamus-neurohypophysis complex with streptozotocin-induced diabetes
Y Luo et al.
BRAIN RESEARCH (2002)
Anti-inflammatory antioxidants attenuate the expression of inducible nitric oxide synthase mediated by advanced glycation endproducts in murine microglia
A Wong et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
Synergistic apoptosis induced by bacterial endotoxin lipopolysaccharide and high glucose in rat microglia
JY Wang et al.
NEUROSCIENCE LETTERS (2001)
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