4.0 Article

Knockdown of circ_CLIP2 regulates the proliferation, metastasis and apoptosis of glioma cells through miR-641/EPHA3/STAT3 axis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Mathematical & Computational Biology

miR-641 Inhibited Cell Proliferation and Induced Apoptosis by Targeting NUCKS1/PI3K/AKT Signaling Pathway in Breast Cancer

Li Li et al.

Summary: The study showed that miR-641 was downregulated in breast cancer and acted as a tumor suppressor by inhibiting proliferation, migration/invasion, and promoting apoptosis of breast cancer cells through targeting NUCKS1 to inhibit the PI3K/AKT signaling pathway.

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2022)

Article Oncology

CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p

Kebin Zheng et al.

Summary: The study revealed that overexpressed CircPIP5K1A in glioma tissues was associated with tumor volume and histopathological grade. Functional experiments showed that overexpressing CircPIP5K1A significantly promoted glioma cell proliferation, invasion, and epithelial-mesenchymal transition, while inhibiting apoptosis.

CANCER CELL INTERNATIONAL (2021)

Article Biochemical Research Methods

Double matrix completion for circRNA-disease association prediction

Zong-Lan Zuo et al.

Summary: The study introduces a double matrix completion method (DMCCDA) to predict potential circRNA-disease associations efficiently. It constructs similarity matrices based on circRNA sequence and semantic disease information, and updates association matrices through matrix multiplication. The DMCCDA model outperforms other approaches in cross-validation, and case studies confirm its effectiveness in recommending circRNAs for diseases in biological experiments.

BMC BIOINFORMATICS (2021)

Article Oncology

Circ_CLIP2 promotes glioma progression through targeting the miR-195-5p/HMGB3 axis

Bing Xiao et al.

Summary: The study showed that Circ_CLIP2 and HMGB3 were upregulated while miR-195-5p was downregulated in glioma cells. Silencing of Circ_CLIP2 inhibited cell proliferation and promoted cell apoptosis. MiR-195-5p inhibited HMGB3 expression by directly targeting HMGB3, leading to the suppression of the Wnt/beta-catenin signaling pathway.

JOURNAL OF NEURO-ONCOLOGY (2021)

Article Oncology

The COX10-AS1/miR-641/E2F6 Feedback Loop Is Involved in the Progression of Glioma

Liang Liu et al.

Summary: This study revealed that COX10-AS1 is upregulated in glioma tissues and cell lines, affecting proliferation, migration, and invasion of glioma cells by acting as a sponge of miR-641 to regulate E2F6. E2F6 can also promote COX10-AS1 expression by binding to its promoter region, suggesting a potential oncogenic role of COX10-AS1 in glioma progression.

FRONTIERS IN ONCOLOGY (2021)

Article Biotechnology & Applied Microbiology

lncRNA SNHG16 promotes glioma tumorigenicity through miR-373/EGFR axis by activating PI3K/AKT pathway

Xiang-Yang Zhou et al.

GENOMICS (2020)

Review Biochemistry & Molecular Biology

Regulatory Mechanism of MicroRNA Expression in Cancer

Zainab Ali Syeda et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Biochemistry & Molecular Biology

Functions and clinical significance of circular RNAs in glioma

Jikui Sun et al.

MOLECULAR CANCER (2020)

Article Biochemistry & Molecular Biology

Circular RNA S-7 promotes ovarian cancer EMT via sponging miR-641 to up-regulate ZEB1 and MDM2

Fenghua Zhang et al.

BIOSCIENCE REPORTS (2020)

Review Biochemistry & Molecular Biology

Critical role of EphA3 in cancer and current state of EphA3 drug therapeutics

Max London et al.

MOLECULAR BIOLOGY REPORTS (2020)

Article Oncology

TheU2AF2/circRNA ARF1/miR-342-3p/ISL2feedback loop regulates angiogenesis in glioma stem cells

Yang Jiang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)

Article Biotechnology & Applied Microbiology

Construction of a circRNA-Related ceRNA Prognostic Regulatory Network in Breast Cancer

Huan Song et al.

ONCOTARGETS AND THERAPY (2020)

Article Biochemistry & Molecular Biology

CircRNA hsa-circ-0014359 promotes glioma progression by regulating miR-153/PI3K signaling

Fei Shi et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Cell Biology

circCPA4 acts as a prognostic factor and regulates the proliferation and metastasis of glioma

Hao Peng et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2019)

Article Oncology

circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma

Jiansheng Chen et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Oncology

CircNFIX promotes progression of glioma through regulating miR-378e/RPN2 axis

Chenyu Ding et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Oncology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

Yibing Yang et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Article Oncology

Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis

Yibing Yang et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)

Editorial Material Clinical Neurology

Therapy Decisions for Patients with High-Grade Glioma and Their Families

Fumio Yamaguchi

WORLD NEUROSURGERY (2017)

Article Biochemistry & Molecular Biology

Circular RNA profile in gliomas revealed by identification tool UROBORUS

Xiaofeng Song et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Medicine, Research & Experimental

Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres

Rajesh Mukthavaram et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Article Cell Biology

EphA3 biology and cancer

Peter W. Janes et al.

GROWTH FACTORS (2014)

Review Clinical Neurology

The role of Stat3 in glioblastoma multiforme

Rodney B. Luwor et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Circular RNAs are a large class of animal RNAs with regulatory potency

Sebastian Memczak et al.

NATURE (2013)

Article Pharmacology & Pharmacy

Targeted delivery of antitumoral therapy to glioma and other malignancies with synthetic chlorotoxin (TM-601)

Adam N. Mamelak et al.

EXPERT OPINION ON DRUG DELIVERY (2007)