4.6 Article

Cortical layering disrupts multi-electrode current steering

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Nanoscience & Nanotechnology

Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration

Sara Cadoni et al.

Summary: Researchers have successfully achieved precise control and activation of retinal and cortical neurons by expressing ultrasound-sensitive proteins and combining unconventional high-frequency ultrasound stimulation. The spatiotemporal resolution and acoustic energy deposit achieved are compatible with the requirements of visual restoration. Sonogenetics provides neuron-specific activation at high spatiotemporal resolution both in retina and in the deep visual cortex, providing a less invasive approach for visual restoration compared to current brain-machine interfaces.

NATURE NANOTECHNOLOGY (2023)

Article Multidisciplinary Sciences

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Marc M. Himmelberg et al.

Summary: Adults have better visual performance for stimuli along the horizontal than vertical and lower than upper vertical meridian, which is paralleled by cortical surface area asymmetries in V1. However, children have similar visual performance for the lower and upper vertical meridian, and similar V1 surface area representing them. This suggests a late-stage change in V1 organization that corresponds to the emergence of visual performance asymmetry in adults along the vertical meridian. The study also shows that many features of V1 are adult-like in children, indicating a developmental change in cortical organization.

NATURE COMMUNICATIONS (2023)

Article Neurosciences

Layer-dependent stability of intracortical recordings and neuronal cell loss

Morgan E. Urdaneta et al.

Summary: Intracortical recordings can be used to control external devices via brain-machine interfaces (BMI), but stability is limited over time due to factors like foreign body response (FBR). Manufacturing advancements have allowed for the development of high-density recording electrodes, but their long-term stability and neuronal cell loss at different cortical depths are unknown. By using a silicon-substrate microelectrode array implanted in rats, we found that the stability of intracortical recordings varied across cortical depth, with electrodes around L4-L5 being the most stable. Additionally, we discovered that neuronal cell loss varied across cortical layers, with L2/3 and L4 electrodes experiencing the largest loss.

FRONTIERS IN NEUROSCIENCE (2023)

Review Anatomy & Morphology

Neurophysiological considerations for visual implants

Sabrina J. Meikle et al.

Summary: Neural implants have the potential to restore visual capabilities in blind individuals through electrical stimulation, with the ultimate goal of emulating naturalistic vision requiring stimulation of multiple brain areas to recreate different aspects of vision.

BRAIN STRUCTURE & FUNCTION (2022)

Review Neurosciences

Effects of General Anesthetics on Synaptic Transmission and Plasticity

Jimcy Platholi et al.

Summary: General anesthetics modulate the function of synapses to produce acute neurophysiological effects, and long-term synaptic dysfunction may lead to undesirable neurocognitive consequences.

CURRENT NEUROPHARMACOLOGY (2022)

Article Engineering, Biomedical

Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array

Joseph T. Sombeck et al.

Summary: This study investigates the responses of neurons to intracortical microstimulation (ICMS) and demonstrates that single pulses of stimulation can induce trans-synaptically evoked activity followed by neural activity suppression. Trains of ICMS result in increased firing rates. These findings provide important insights into the understanding of circuit connectivity and cortical function, and can inform the design of stimulation patterns for improving afferent interfaces for artificial sensory feedback.

JOURNAL OF NEURAL ENGINEERING (2022)

Article Engineering, Biomedical

Improving the spatial resolution of artificial vision using midget retinal ganglion cell populations modeled at the human fovea

Michael L. Italiano et al.

Summary: This study developed an anatomically accurate 3D model of RGC populations within the human central retina and demonstrated the potential for an epiretinal hexapolar configuration to achieve consistent, spatially confined retinal responses even within the unique and neuron-dense foveal region.

JOURNAL OF NEURAL ENGINEERING (2022)

Article Clinical Neurology

Percepts evoked by multi-electrode stimulation of human visual cortex

William H. Bosking et al.

Summary: This study investigated the perception of phosphenes evoked by multi-electrode stimulation in the visual cortex of human epilepsy patients. The results showed that simultaneous stimulation of multiple electrodes resulted in varying patterns of phosphenes, with significant variations in location, size, and orientation. While the multi-electrode stimulation did not produce recognizable forms, subjects were able to use the pattern of phosphenes for simple discriminations.

BRAIN STIMULATION (2022)

Article Engineering, Biomedical

Intracortical current steering shifts the location of evoked neural activity

Sabrina J. Meikle et al.

Summary: This study investigates whether current steering technique can enhance the resolution of artificial vision without increasing the number of physical electrodes implanted in the brain. The results show that current steering can systematically shift the activation location of neurons and improve the effectiveness of artificial vision.

JOURNAL OF NEURAL ENGINEERING (2022)

Article Multidisciplinary Sciences

POLYRETINA restores light responses in vivo in blind Gottingen minipigs

Paola Vagni et al.

Summary: POLYRETINA, a large and high-density photovoltaic epiretinal device, has the potential to restore light-evoked cortical responses in blind animals at safe irradiance levels. This technology holds promise for providing artificial vision to completely blind patients affected by diseases such as retinitis pigmentosa.

NATURE COMMUNICATIONS (2022)

Article Neurosciences

Reducing Behavioral Detection Thresholds per Electrode via Synchronous, Spatially-Dependent Intracortical Microstimulation

Nicolas G. Kunigk et al.

Summary: This study investigates the effectiveness of simultaneous multi-channel ICMS in electrode arrays with stimulation sites spanning cortical depth. The results show that using two adjacent electrode sites for stimulation reduces the charge required to reach detection thresholds by half. The reduction in threshold charge is more significant with more stimulation channels and decreases with greater distance between channels. These improvements are due to charge summation rather than a summation of neural responses to stimulation. Additionally, the improved stimulation efficiency per electrode site is seen regardless of the cortical depth of each channel. This has implications for future advanced neuroprosthetic devices.

FRONTIERS IN NEUROSCIENCE (2022)

Review Ophthalmology

Implications of Neural Plasticity in Retinal Prosthesis

Daniel Caravaca-Rodriguez et al.

Summary: Retinal degenerative diseases result in vision loss due to neural rewiring cascade. Activating retinal neurons via implants faces challenges of unselective activation patterns and pre-existing neural rewiring. Modulating neural rewiring may be crucial for improving artificial vision and neurorehabilitation strategies.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2022)

Article Clinical Neurology

Configuring intracortical microelectrode arrays and stimulus parameters to minimize neuron loss during prolonged intracortical electrical stimulation

Douglas McCreery et al.

Summary: The study aimed to determine microstimulation parameters that can activate neurons in the feline cerebral cortex without causing neuron loss. Results showed minimal neuron loss at lower stimulation parameters, but significant loss at higher parameters, especially near the stimulated microelectrodes. Stimulation-induced loss was similar for different types of neurons, and electrodes in the medullary pyramidal tract recorded neuronal activity evoked by stimulation in the cerebral cortex.

BRAIN STIMULATION (2021)

Article Public, Environmental & Occupational Health

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

Rupert R. A. Bourne et al.

Summary: The age-adjusted prevalence of blindness has decreased over the past three decades, but the number of people affected has actually increased due to population growth. By 2050, it is predicted that there will be an increase in the number of individuals suffering from vision impairments, highlighting the need for continued efforts in addressing this global issue.

LANCET GLOBAL HEALTH (2021)

Article Clinical Neurology

Microstimulation-evoked neural responses in visual cortex are depth dependent

Tim Allison-Walker et al.

Summary: The depth of electrode stimulation affects neural responses in the cortex, with superficial stimulation sites exhibiting higher firing rates and lower thresholds, while deep stimulation evokes more widespread activity across the cortical column.

BRAIN STIMULATION (2021)

Article Medicine, Research & Experimental

Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex

Eduardo Fernandez et al.

Summary: The study implanted a microelectrode array in the visual cortex of a completely blind patient, achieving initial success in restoring vision through simultaneous stimulation with multiple electrodes, allowing the blind individual to recognize some letters and object boundaries.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Article Clinical Neurology

Phosphene perceptions and safety of chronic visual cortex stimulation in a blind subject

Soroush Niketeghad et al.

JOURNAL OF NEUROSURGERY (2020)

Article Biochemistry & Molecular Biology

Dynamic Stimulation of Visual Cortex Produces Form Vision in Sighted and Blind Humans

Michael S. Beauchamp et al.

Article Audiology & Speech-Language Pathology

Dynamic current steering with phantom electrode in cochlear implants

Xin Luo et al.

HEARING RESEARCH (2020)

Review Behavioral Sciences

Neuroplasticity in adult human visual cortex

Elisa Castaldi et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2020)

Article Engineering, Biomedical

Tissue response to a chronically implantable wireless intracortical visual prosthesis (Gennaris array)

Jeffrey Rosenfeld et al.

JOURNAL OF NEURAL ENGINEERING (2020)

Article Multidisciplinary Sciences

Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex

Xing Chen et al.

SCIENCE (2020)

Article Engineering, Biomedical

CMOS stimulating chips capable of wirelessly driving 473 electrodes for a cortical vision prosthesis

Yan T. Wong et al.

JOURNAL OF NEURAL ENGINEERING (2019)

Article Engineering, Biomedical

Focal activation of neuronal circuits induced by microstimulation in the visual cortex

Yuta Tanaka et al.

JOURNAL OF NEURAL ENGINEERING (2019)

Article Multidisciplinary Sciences

Layer 4 of mouse neocortex differs in cell types and circuit organization between sensory areas

Federico Scala et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Reconstruction and Simulation of Neocortical Microcircuitry

Henry Markram et al.

Article Neurosciences

The neocortical microcircuit collaboration portal: a resource for rat somatosensory cortex

Srikanth Ramaswamy et al.

FRONTIERS IN NEURAL CIRCUITS (2015)

Article Multidisciplinary Sciences

Design and Evaluation of a Cochlear Implant Strategy Based on a Phantom Channel

Waldo Nogueira et al.

PLOS ONE (2015)

Article Neurosciences

Inhibition of Return Impairs Phosphene Detection

Daniel T. Smith et al.

JOURNAL OF COGNITIVE NEUROSCIENCE (2012)

Review Neurosciences

The origin of extracellular fields and currents - EEG, ECoG, LFP and spikes

Gyoergy Buzsaki et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Review Biochemistry & Molecular Biology

The in vivo neurochemistry of the brain during general anesthesia

Christian P. Mueller et al.

JOURNAL OF NEUROCHEMISTRY (2011)

Article Neurosciences

How Local Is the Local Field Potential?

Yoshinao Kajikawa et al.

NEURON (2011)

Article Engineering, Electrical & Electronic

Biological-Machine Systems Integration: Engineering the Neural Interface

Nigel H. Lovell et al.

PROCEEDINGS OF THE IEEE (2010)

Article Clinical Neurology

Current steering to control the volume of tissue activated during deep brain stimulation

Christopher R. Butson et al.

BRAIN STIMULATION (2008)

Article Biochemical Research Methods

Over-pulsing degrades activated iridium oxide films used for intracortical neural stimulation

SF Cogan et al.

JOURNAL OF NEUROSCIENCE METHODS (2004)

Article Engineering, Biomedical

Contribution to the theory of prosthetic vision

LE Hallum et al.

ASAIO JOURNAL (2004)