☆ 4.7 Article

Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.

JOURNAL OF NATURAL PRODUCTS (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Organic

Structural Diversity of Perylenequinones Is Driven by Their Redox Behavior

Zeinab Y. Al Subeh et al.

Summary: This study isolated and characterized the long-postulated biosynthetic precursor of class B fungal perylenequinones from a Shiraia-like sp. Furthermore, it investigated the structural relationship and redox behaviors of hypocrellins and hypomycins. The study found that hypocrellins can undergo reversible reduction and reoxidation under aerobic conditions, and can undergo ring closing metathesis under anaerobic conditions.

JOURNAL OF ORGANIC CHEMISTRY (2022)

添加到收藏夹

Article Plant Sciences

Discovery of Anticancer Agents of Diverse Natural Origin

Leslie N. Aldrich et al.

Summary: Research progress in the discovery of potential anticancer agents from various organisms has been summarized. Lead compounds with structural diversity have been obtained, and potential antitumor activities have been demonstrated. Further investigations are warranted for promising lead compounds.

JOURNAL OF NATURAL PRODUCTS (2022)

添加到收藏夹

Article Plant Sciences

Pyrrospirones K-Q, Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus Penicillium sp. SCSIO 41512

Fei-Hua Yao et al.

Summary: Seven new decahydrofluorene-class alkaloids, pyrrospirones K-Q (1-7), were isolated from the marine-derived fungal strain Penicillium sp. SCSIO 41512. Compound 13 exhibited significant inhibitory activity against protein tyrosine phosphatases. Moreover, compounds 1, 2, 5, 8-10, 12, and 13 showed antibacterial activity.

JOURNAL OF NATURAL PRODUCTS (2022)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Thielavins: tuned biosynthesis and LR-HSQMBC for structure elucidation

Zeinab Y. Al Subeh et al.

Summary: The study revealed that fungal Shiraia-like sp. showed enhanced biosynthesis of thielavins when using rice as a substrate and with a 12:12 hour light:dark cycle. The structure of the previously undescribed thielavin Z was determined using NMR experiments, demonstrating the utility of LR-HSQMBC and NOESY NMR experiments in structural elucidation of these hydrogen-deficient natural products. Compounds 1-4 exhibited cytotoxic activity against human breast, ovarian, and melanoma cancer cell lines at the micromolar level.

JOURNAL OF ANTIBIOTICS (2021)

添加到收藏夹

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

添加到收藏夹

Review Plant Sciences

Biologically Significant and Recently Isolated Alkaloids from Endophytic Fungi

Sharna-kay Daley et al.

Summary: This review examines established and recently characterized alkaloids from plant- and some marine-associated endophytic fungi, focusing on their biological significance.

JOURNAL OF NATURAL PRODUCTS (2021)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

Occasional comment: Fungal identification to species-level can be challenging

Huzefa A. Raja et al.

PHYTOCHEMISTRY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biosynthesis of para-Cyclophane-Containing Hirsutellone Family of Fungal Natural Products

Masao Ohashi et al.

Summary: Hirsutellones are fungal natural products with a macrocyclic structure, and the biosynthetic pathway involves the cooperative action of several proteins, such as oxidoreductase and lipocalin-like protein, in oxidative cyclization and exo-specific cycloaddition processes.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Media and strain studies for the scaled production of cis-enone resorcylic acid lactones as feedstocks for semisynthesis

Zeinab Y. Al Subeh et al.

Summary: This study aimed to identify fungi that biosynthesize compounds 1 and 2, optimize fermentation conditions on a lab scale, and develop straightforward purification processes. Gram-scale quantities of RALs and other compounds were successfully obtained as a result.

JOURNAL OF ANTIBIOTICS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Diversity in Chemical Structures and Biological Properties of Plant Alkaloids

Sweta Bhambhani et al.

Summary: Alkaloids, a class of plant specialized metabolites with diverse biological activities, have been utilized in traditional and modern healthcare systems for the treatment of various ailments. Research on alkaloids is crucial for enhancing biological properties and productivity, with alternative methods like heterologous and homologous systems being explored. Chemical modifications during alkaloidal conversions play a key role in conferring biological activities, with potential commercial applications in the marketplace.

MOLECULES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Bioactive Secondary Metabolites from Endophytic Fungi

Elena Ancheeva et al.

CURRENT MEDICINAL CHEMISTRY (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

PhyloSuite: An integrated and scalable desktop platform for streamlined molecular sequence data management and evolutionary phylogenetics studies

Dong Zhang et al.

MOLECULAR ECOLOGY RESOURCES (2020)

添加到收藏夹

Article Oncology

Cancer statistics, 2020

Rebecca L. Siegel et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

添加到收藏夹

Article Mycology

Sarocladium species associated with rice in Taiwan

Jie-Hao Ou et al.

MYCOLOGICAL PROGRESS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Mechanisms of Multidrug Resistance in Cancer Chemotherapy

Karol Bukowski et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Plant Sciences

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

David J. Newman et al.

JOURNAL OF NATURAL PRODUCTS (2020)

添加到收藏夹

Article Mycology

Sarocladium graminicola, a new endophytic species from tropical grasses

Rafaela M. Anjos et al.

MYCOLOGICAL PROGRESS (2020)

添加到收藏夹

Article Plant Sciences

The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids

Laura Flores-Bocanegra et al.

JOURNAL OF NATURAL PRODUCTS (2020)

添加到收藏夹

Article Plant Sciences

Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones

Zeinab Y. Al Subeh et al.

JOURNAL OF NATURAL PRODUCTS (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Drug resistance in cancer: mechanisms and tackling strategies

Tanweer Haider et al.

PHARMACOLOGICAL REPORTS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Didymellanosine, a new decahydrofluorene analogue, and ascolactone C from Didymella sp. IEA-3B.1, an endophyte of Terminalia catappa

Ni P. Ariantari et al.

RSC ADVANCES (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Extracting value: mechanistic insights into the formation of natural product artifacts - case studies in marine natural products

Robert J. Capon

NATURAL PRODUCT REPORTS (2020)

添加到收藏夹

Article Plant Sciences

Ascomylactams A-C, Cytotoxic 12-or 13-Membered-Ring Macrocyclic Alkaloids Isolated from the Mangrove Endophytic Fungus Didymella sp. CYSK-4, and Structure Revisions of Phomapyrrolidones A and C

Yan Chen et al.

JOURNAL OF NATURAL PRODUCTS (2019)

添加到收藏夹

Article Plant Sciences

A pyrrocidine derivative produced by fungus Neonectria ramulariae In-2 isolated from a Beetle Holotrichia picea

Yoshihito Shiono et al.

PHYTOCHEMISTRY LETTERS (2018)

添加到收藏夹

Article Chemistry, Organic

New bioactive pyrrospirones C-I from a marine-derived fungus Penicillium sp ZZ380

Tengfei Song et al.

TETRAHEDRON (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

Endophytic Fungi-Alternative Sources of Cytotoxic Compounds: A Review

Fazilath Uzma et al.

FRONTIERS IN PHARMACOLOGY (2018)

添加到收藏夹

Review Plant Sciences

Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community

Huzefa A. Raja et al.

JOURNAL OF NATURAL PRODUCTS (2017)

添加到收藏夹

Article Biochemical Research Methods

ModelFinder: fast model selection for accurate phylogenetic estimates

Subha Kalyaanamoorthy et al.

NATURE METHODS (2017)

添加到收藏夹

Article Mycology

Sarocladium brachiariae sp nov., an endophytic fungus isolated from Brachiaria brizantha

X. B. Liu et al.

MYCOSPHERE (2017)

添加到收藏夹

Review Pharmacology & Pharmacy

The Different Mechanisms of Cancer Drug Resistance: A Brief Review

Behzad Mansoori et al.

ADVANCED PHARMACEUTICAL BULLETIN (2017)

添加到收藏夹

Review Oncology

Discovery of Anticancer Agents of Diverse Natural Origin

A. Douglas Kinghorn et al.

ANTICANCER RESEARCH (2016)

添加到收藏夹

Article Microbiology

Biologically Active Secondary Metabolites from the Fungi

Gerald F. Bills et al.

MICROBIOLOGY SPECTRUM (2016)

添加到收藏夹

Article Mycology

Phylogeny of Sarocladium (Hypocreales)

A. Giraldo et al.

PERSOONIA (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

Lam-Tung Nguyen et al.

MOLECULAR BIOLOGY AND EVOLUTION (2015)

添加到收藏夹

Article Plant Sciences

Sarocladium spinificis, a new endophytic species from the coastal grass Spinifex littoreus in Taiwan

Yu-Hung Yeh et al.

BOTANICAL STUDIES (2014)

添加到收藏夹

Article Chemistry, Medicinal

SpecDis: Quantifying the Comparison of Calculated and Experimental Electronic Circular Dichroism Spectra

Torsten Bruhn et al.

CHIRALITY (2013)

添加到收藏夹

Article Chemistry, Medicinal

Embellicines A and B: Absolute Configuration and NF-κB Transcriptional Inhibitory Activity

Weaam Ebrahim et al.

JOURNAL OF MEDICINAL CHEMISTRY (2013)

添加到收藏夹

Article Plant Sciences

Phomapyrrolidones A-C, Antitubercular Alkaloids from the Endophytic Fungus Phoma sp. NRRL 46751

E. M. Kithsiri Wijeratne et al.

JOURNAL OF NATURAL PRODUCTS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Ultrafast Approximation for Phylogenetic Bootstrap

Bui Quang Minh et al.

MOLECULAR BIOLOGY AND EVOLUTION (2013)

添加到收藏夹

Review Biochemistry & Molecular Biology

Hirsutellones and beyond: figuring out the biological and synthetic logics toward chemical complexity in fungal PKS-NRPS compounds

Xu-Wen Li et al.

NATURAL PRODUCT REPORTS (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Antimicrobial and cytotoxic secondary metabolites from tropical leaf endophytes: Isolation of antibacterial agent pyrrocidine C from Lewia infectoria SNB-GTC2402

Thiago M. Casella et al.

PHYTOCHEMISTRY (2013)

添加到收藏夹

Article Mycology

Acremonium phylogenetic overview and revision of Gliomastix, Sarocladium, and Trichothecium

R. C. Summerbell et al.

STUDIES IN MYCOLOGY (2011)

添加到收藏夹

Review Chemistry, Medicinal

ECD Cotton Effect Approximated by the Gaussian Curve and Other Methods

Philip J. Stephens et al.

CHIRALITY (2010)

添加到收藏夹

Article Chemistry, Organic

Determination of Absolute Configuration of Natural Products: Theoretical Calculation of Electronic Circular Dichroism as a Tool

Xing-Cong Li et al.

CURRENT ORGANIC CHEMISTRY (2010)

添加到收藏夹

Article Evolutionary Biology

Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments

Gerard Talavera et al.

SYSTEMATIC BIOLOGY (2007)

添加到收藏夹

Article Chemistry, Organic

Hirsutellone F, a dimer of antitubercular alkaloids from the seed fungus Trichoderma species BCC 7579

Masahiko Isaka et al.

ORGANIC LETTERS (2006)

添加到收藏夹

Article Chemistry, Organic

Hirsutellones A-E, antimycobacterial alkaloids from the insect pathogenic fungus Hirsutella nivea BCC 2594

M Isaka et al.

TETRAHEDRON (2005)

添加到收藏夹

Review Evolutionary Biology

Model selection and model averaging in phylogenetics: Advantages of akaike information criterion and Bayesian approaches over likelihood ratio tests

D Posada et al.

SYSTEMATIC BIOLOGY (2004)

添加到收藏夹

Article Chemistry, Organic

Biosynthesis of structurally unique fungal metabolite GKK1032A2:: Indication of novel carbocyclic formation mechanism in polyketide biosynthesis

H Oikawa

JOURNAL OF ORGANIC CHEMISTRY (2003)

添加到收藏夹

Article Chemistry, Organic

Pyrrocidines A and B, new antibiotics produced by a filamentous fungus

HY He et al.

TETRAHEDRON LETTERS (2002)

添加到收藏夹

Article Biochemistry & Molecular Biology

Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis

J Castresana

MOLECULAR BIOLOGY AND EVOLUTION (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.