相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network
Jan Skacel et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Amitriptyline inhibits nonalcoholic steatohepatitis and atherosclerosis induced by high-fat diet and LPS through modulation of sphingolipid metabolism
Zhongyang Lu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)
Discovery of Potent, Selective, and Direct Acid Sphingomyelinase Inhibitors with Antidepressant Activity
Kan Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Sphingolipids and their metabolism in physiology and disease
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model
Kan Yang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Research Progress on the Relationship between Atherosclerosis and Inflammation
Yuhua Zhu et al.
BIOMOLECULES (2018)
Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia
Saisudha Koka et al.
REDOX BIOLOGY (2017)
Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis
Colin Niaudet et al.
CELLULAR SIGNALLING (2017)
Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation
Andreas Edsfeldt et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Atherosclerosis Successes, Surprises, and Future Challenges
Peter Libby et al.
CIRCULATION RESEARCH (2016)
oxLDL and eLDL Induced Membrane Microdomains in Human Macrophages
Stefan Wallner et al.
PLOS ONE (2016)
Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate
Antonio Gomez-Munoz et al.
PROGRESS IN LIPID RESEARCH (2016)
Crystal structure of mammalian acid sphingomyelinase
Alexei Gorelik et al.
NATURE COMMUNICATIONS (2016)
Secretory sphingomyelinase in health and disease
Johannes Kornhuber et al.
BIOLOGICAL CHEMISTRY (2015)
Diaphragm dysfunction caused by sphingomyelinase requires the p47phox subunit of NADPH oxidase
Elaina R. Bost et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2015)
Elevation of ceramide and activation of secretory acid sphingomyelinase in patients with acute coronary syndromes
Wei Pan et al.
CORONARY ARTERY DISEASE (2014)
Defining a Role for Acid Sphingomyelinase in the p38/Interleukin-6 Pathway
David M. Perry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Endogenous Ceramide Contributes to the Transcytosis of oxLDL across Endothelial Cells and Promotes Its Subendothelial Retention in Vascular Wall
Wenjing Li et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet
Gergana M. Deevska et al.
BIOSCIENCE REPORTS (2012)
Mechanistic roles of lipoprotein lipase and sphingomyelinase in low density lipoprotein aggregation
Michael J. Walters et al.
JOURNAL OF COLLOID AND INTERFACE SCIENCE (2011)
A Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of gamma-Pyrones
Stefan Wetzel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Potent and Selective Inhibition of Acid Sphingomyelinase by Bisphosphonates
Anke G. Roth et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Potent Inhibition of Acid Sphingomyelinase by Phosphoinositide Analogues
Anke Gundula Roth et al.
CHEMBIOCHEM (2009)
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model
Johannes Kornhuber et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
TRAIL activates acid sphingomyelinase via a redox mechanism and releases ceramide to trigger apoptosis
C. A. Dumitru et al.
ONCOGENE (2006)
Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine
M Kölzer et al.
FEBS LETTERS (2004)