相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors
Russell Fritzemeier et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
Thanh Nha Uyen Le et al.
CELL REPORTS (2022)
Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions
Zafrul Hasan et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2022)
Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney
Shinji Tanaka et al.
SCIENCE TRANSLATIONAL MEDICINE (2022)
Therapeutic Potential of SphK1 Inhibitors Based on Abnormal Expression of SphK1 in Inflammatory Immune Related-Diseases
Yanhong Bu et al.
FRONTIERS IN PHARMACOLOGY (2021)
Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases
Bisera Stepanovska et al.
PHARMACOLOGICAL RESEARCH (2020)
Ozanimod to Treat Relapsing Forms of Multiple Sclerosis: A Comprehensive Review of Disease, Drug Efficacy and Side Effects
Grace Lassiter et al.
NEUROLOGY INTERNATIONAL (2020)
Siponimod: A Review in Secondary Progressive Multiple Sclerosis
Lesley J. Scott
CNS DRUGS (2020)
High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node
Szandor Simmons et al.
ELIFE (2019)
Sphingosine 1-phosphate: Lipid signaling in pathology and therapy
Andreane Cartier et al.
SCIENCE (2019)
Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells
Olivier Blanchard et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
MFSD2B is a sphingosine 1-phosphate transporter in erythroid cells
Naoki Kobayashi et al.
SCIENTIFIC REPORTS (2018)
Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets
Thiet M. Vu et al.
NATURE (2017)
Sphingosine 1-Phosphate Receptor Modulators for the Treatment of Multiple Sclerosis
Burhan Z. Chaudhry et al.
NEUROTHERAPEUTICS (2017)
Long-term (up to 4.5 years) treatment with fingolimod in multiple sclerosis: results from the extension of the randomised TRANSFORMS study
Jeffrey A. Cohen et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2016)
Sphingosine kinase inhibitors: a review of patent literature (2006-2015)
Kevin R. Lynch et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases
Michael S. Donoviel et al.
FASEB JOURNAL (2015)
Cardiac and vascular effects of fingolimod: Mechanistic basis and clinical implications
John Camm et al.
AMERICAN HEART JOURNAL (2014)
Oral ponesimod in relapsing-remitting multiple sclerosis: a randomised phase II trial
Tomas Olsson et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)
Sphingolipid metabolites in inflammatory disease
Michael Maceyka et al.
NATURE (2014)
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
Masayuki Nagahashi et al.
FASEB JOURNAL (2013)
Roles, regulation and inhibitors of sphingosine kinase 2
Heidi A. Neubauer et al.
FEBS JOURNAL (2013)
Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond
Gregory T. Kunkel et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs
Jason G. Cyster et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
Shigetomo Fukuhara et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
The Role of Sphingosine-1-Phosphate Transporter Spns2 in Immune System Function
Anastasia Nijnik et al.
JOURNAL OF IMMUNOLOGY (2012)
Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells
Yu Hisano et al.
PLOS ONE (2012)
The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate
Alejandra Mendoza et al.
CELL REPORTS (2012)
Mechanisms of Fingolimod's Efficacy and Adverse Effects in Multiple Sclerosis
Jeffrey A. Cohen et al.
ANNALS OF NEUROLOGY (2011)
The outs and the ins of sphingosine-1-phosphate in immunity
Sarah Spiegel et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Mitsunobu and Related Reactions: Advances and Applications
K. C. Kumara Swamy et al.
CHEMICAL REVIEWS (2009)
The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors
Atsuo Kawahara et al.
SCIENCE (2009)
The vascular S1P gradient - Cellular sources and biological significance
Timothy Hla et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2008)
The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish
Nick Osborne et al.
CURRENT BIOLOGY (2008)
Sphingosine 1-phosphate and ceramide 1-phosphate: Expanding roles in cell signaling
CE Chalfant et al.
JOURNAL OF CELL SCIENCE (2005)
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
SR Schwab et al.
SCIENCE (2005)
FTY720: Sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function
V Brinkmann et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Palladium catalysts for the Suzuki cross-coupling reaction: An overview of recent advances
F Bellina et al.
SYNTHESIS-STUTTGART (2004)
Phosphorylation of the immunomodulatory drug FTY720 by sphingosine kinases
A Billich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
V Brinkmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)