Presymptomatic viral shedding in high-risk mpox contacts: A prospective cohort study

Letter Infectious Diseases

People with asymptomatic or unrecognised infection potentially contribute to monkeypox virus transmission

Silvia Accordini et al.

LANCET MICROBE (2023)

Article Immunology

The Roles of Unrecognized Monkeypox Cases, Contact Isolation and Vaccination in Determining Epidemic Size in Belgium: A Modeling Study

Christophe Van Dijck et al.

Summary: This study used a network model to simulate a monkeypox epidemic among men who have sex with men. The findings suggest that unidentified infections play a crucial role in the epidemic, and vaccinating individuals at highest risk of infection is more effective in reducing the size of the epidemic compared to post-exposure vaccination of sexual partners.

CLINICAL INFECTIOUS DISEASES (2023)

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Article Infectious Diseases

Viral loads in clinical samples of men with monkeypox virus infection: a French case series

Romain Palich et al.

Summary: This study describes the distribution of Monkeypox virus (MPXV) in the human body, and the results show that the virus is more frequently detected and has higher viral loads in the skin, anus, and throat. These findings suggest that transmission most likely occurs through direct body contact.

LANCET INFECTIOUS DISEASES (2023)

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Editorial Material Infectious Diseases

Monkeypox virus in human body sites and fluids: evidence for transmission

Francesca Colavita et al.

LANCET INFECTIOUS DISEASES (2023)

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Article Immunology

Evaluating the Accuracy of Self-Collected Swabs for the Diagnosis of Monkeypox

Maria Ubals et al.

Summary: The accuracy of self-collected samples for diagnosing monkeypox was evaluated in a study of 50 individuals. Results showed that self-sampling performed similarly to physician-collected samples, suggesting it as a reliable strategy for diagnosis.

CLINICAL INFECTIOUS DISEASES (2023)

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Letter Medicine, General & Internal

Detection of Monkeypox Virus in Anorectal Swabs From Asymptomatic Men Who Have Sex With Men in a Sexually Transmitted Infection Screening Program in Paris, France

Valentine Marie Ferre et al.

ANNALS OF INTERNAL MEDICINE (2022)

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Article Biochemistry & Molecular Biology

Retrospective detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium

Irith De Baetselier et al.

Summary: The magnitude of the 2022 monkeypox virus outbreak has exceeded any previous outbreak, and undiagnosed infections may be driving the epidemic. A study found four men attending a Belgian sexual health clinic to be infected with monkeypox. One man had a painful rash while the other three were asymptomatic, but their infections were confirmed through clinical examination. These findings suggest that undiagnosed cases of monkeypox could contribute to the transmission and scale of the 2022 outbreak.

NATURE MEDICINE (2022)

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Article Medicine, General & Internal

Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022

John P. Thornhill et al.

Summary: This report describes 528 cases of monkeypox in 16 countries. Common clinical findings include rash, mucosal lesions, fever, lethargy, and lymphadenopathy. Few patients required hospitalization.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Review Medicine, General & Internal

Monkeypox

Antoine Gessain et al.

Summary: The article reviews the virology, epidemiology, clinical features, and treatment of monkeypox, and discusses the reported cases in the United Kingdom, Portugal, and Italy in May 2022, which led to the declaration of a global health emergency by the WHO.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Medicine, General & Internal

Transmission dynamics of monkeypox in the United Kingdom: contact tracing study

Thomas Ward et al.

Summary: This study analyzed the transmission dynamics of the monkeypox outbreak in the UK and found a significant amount of asymptomatic transmission and a prolonged infectious period.

BMJ-BRITISH MEDICAL JOURNAL (2022)

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Editorial Material Medicine, General & Internal