期刊
JOURNAL OF MEDICAL VIROLOGY
卷 95, 期 3, 页码 -出版社
WILEY
DOI: 10.1002/jmv.28653
关键词
adenovirus; adenovirus type D109; adenovirus type D110; febrile respiratory illness; human adenovirus species D
类别
Two new genotypes of human mastadenovirus D, designated 109 and 110, were isolated from unrelated cases of acute respiratory disease detected at the California/Mexico border in January 2018. Both genotypes are examples of intertypic recombination and contribute to the understanding of the expanded tissue tropism of certain members of species HAdV-D.
Two novel genotypes of species human mastadenovirus D designated 109 and 110 were isolated from three epidemiologically unrelated cases of acute respiratory disease detected in January 2018 by surveillance efforts at the California/Mexico border. Both genotypes represent examples of intertypic recombination. Genotype D109 is most closely related to genotype D56 (97.68% genomic similarity) and features a type D22-like penton base, a type D19-like hexon gene, and a type D9-like fiber [P22/H19/F9]. On the other hand, genotype D110 is most closely related to type D22 (96.94% genomic similarity) and features a type D67-like penton base, a novel hexon gene, and a type D9-like fiber [P67/H110/F9]. Importantly, the fibers of both novel genotypes are highly similar to those of genotypes D56 and D59, which have also been isolated from a few cases of respiratory infections. The present report shows data contributing to the understanding of the molecular determinants of the expanded tissue tropism of certain members of species HAdV-D.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据