期刊
JOURNAL OF MEDICAL MICROBIOLOGY
卷 72, 期 3, 页码 -出版社
MICROBIOLOGY SOC
DOI: 10.1099/jmm.0.001674
关键词
arbovirus; exanthema; fever; viral arthritis
类别
Sindbis virus is a causative agent of febrile infection in northern Europe. Symptoms include joint inflammation, fever, rash, and fatigue. The virus is mainly transmitted by mosquitoes, and wild birds act as amplifying hosts for its spread.
Sindbis virus (SINV) is the causative agent of a febrile infection commonly called Ockelbo disease, Pogosta disease or Karelian fever in northern Europe. Finland, Sweden, Russia and South Africa experience periodic SINV outbreaks. SINV is classified within the family Togaviridae and genus Alphavirus. Symptoms of SINV infection in humans include joint inflammation and pain, fever, rash and fatigue. In some cases, joint symptoms can persist for years after recovery from the initial infection. Clinical signs of SINV infection are rarely reported in animals, although infection in horses has been documented. There is no specific treatment or vaccination. The virus is transmitted by mosquitoes, particularly those belonging to the Culex genus, but Aedes, Culiseta or Mansonia species may also act as vectors. Wild birds act as amplifying hosts and are implicated in the long-distance spread of the virus.
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