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2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA)

JOURNAL OF HYPERTENSION (2023)

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Review Cardiac & Cardiovascular Systems

Research strategies in treatment of hypertension: value of retrospective real-life data

Giovanni Corrao et al.

Summary: This article discusses the limitations of data collected from randomized controlled trials (RCTs) and argues that these limitations can be partially overcome through modifications of RCT design and conduction, but further supplemented by real-life research. The focus is on retrospective analysis of healthcare utilization databases, which provide low-cost information on various healthcare issues and have advantages such as the ability to capture long-term data and information on specific subgroups.

EUROPEAN HEART JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis

Rajiv Agarwal et al.

Summary: The study found that finerenone can reduce the risk of kidney disease and cardiovascular events in patients with type 2 diabetes. Screening patients for albuminuria can help reduce the burden of cardiovascular and kidney disease.

EUROPEAN HEART JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study

Pauline Boucheron et al.

Summary: This nationwide cohort study found that hypertensive disorders of pregnancy greatly increased the risk of chronic hypertension in primiparous women in the first years following childbirth. Women with HDP were more likely to develop chronic hypertension and sought medical help earlier.

EUROPEAN HEART JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement

Joerg Herrmann et al.

Summary: The discipline of Cardio-Oncology focuses on the cardiovascular care of cancer patients and the management of cardiovascular complications of cancer therapies. This document provides consensus definitions for common cardiovascular toxicities and aims to improve communication and outcomes in clinical practice and research.

EUROPEAN HEART JOURNAL (2022)

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Review Transplantation

Renal denervation: where do we stand and what is the relevance to the nephrologist?

Roland E. Schmieder

Summary: Catheter-based renal denervation has emerged as a promising treatment option for reducing high blood pressure in patients with chronic kidney disease. This review examines the role of the kidney and neurohormonal activation in hypertension development and discusses the effectiveness and tolerability of renal denervation from the perspective of nephrologists, with a focus on its potential future role in managing hypertension in CKD patients.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2022)

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Article Peripheral Vascular Disease

Blood Pressure and Arterial Stiffness in Association With Aircraft Noise Exposure:Long-Term Observation and Potential Effect of COVID-19 Lockdown

Wiktoria Wojciechowska et al.

Summary: This study reveals the association between long-term exposure to aircraft noise and increased prevalence of hypertension and arterial stiffening. However, even short-term noise reduction during the COVID-19 lockdown can reverse these unfavorable effects.

HYPERTENSION (2022)

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Editorial Material Peripheral Vascular Disease

How Low Should You Go in the Presence of Frailty?

Michelle C. Odden et al.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Prognostic Value of Changes in Aortic Stiffness for Cardiovascular Outcomes and Mortality in Resistant Hypertension: a Cohort Study

Claudia R. L. Cardoso et al.

Summary: The prognostic importance of changes in aortic stiffness for adverse cardiovascular outcomes and mortality in patients with resistant hypertension was investigated. The study found that reducing or preventing progression of aortic stiffness was associated with significant cardiovascular protection in these patients, suggesting that it may be an additional target for antihypertensive treatment.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Systolic Blood Pressure and Mortality in Community-Dwelling Older Adults: Frailty as an Effect Modifier

Kaj-Marko Kremer et al.

Summary: Current evidence is insufficient to support different hypertension treatment targets in older adults. This study evaluated whether frailty modifies the association between systolic blood pressure (SBP) and 8-year all-cause mortality in community-dwelling older adults. The results suggest that frailty may have a protective effect on all-cause mortality in frail older adults with respect to elevated SBP.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Nonadherence in Hypertension: How to Develop and Implement Chemical Adherence Testing

Dan Lane et al.

Summary: Nonadherence to antihypertensive medication is common, and chemical adherence testing is a reliable method to detect nonadherence, especially in patients with apparent treatment-resistant hypertension. Testing should be done in specific situations, such as in those with resistant hypertension or those on multiple antihypertensives with inadequate blood pressure control. Verbal consent should be obtained before testing, and results should be discussed with the patient for better understanding.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Effects of Arterial Stiffness and Carotid Intima-Media Thickness Progression on the Risk of Overweight/Obesity and Elevated Blood Pressure/Hypertension: a Cross-Lagged Cohort Study

Andrew O. Agbaje et al.

Summary: This study found that arterial stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), was associated with the risk of overweight/obesity and elevated blood pressure/hypertension in adolescents. However, carotid intima-media thickness (cIMT) had no associations with these risks. Progression of cfPWV was directly associated with an increase in systolic and diastolic blood pressure, while cIMT progression was associated with adiposity measures and diastolic blood pressure. These findings suggest the importance of preventing arterial stiffness, particularly in the context of obesity and hypertension.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Unique Associations of DNA Methylation Regions With 24-Hour Blood Pressure Phenotypes in Blacks

Michelle L. Roberts et al.

Summary: This study identified DNA methylation regions that are significantly associated with 24-hour blood pressure phenotypes, which may serve as important markers for blood pressure regulation. The newly developed methylation sequencing method has potential for clinical testing and large-scale population screenings.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

New Noninvasive Methods to Evaluate Microvascular Structure and Function

Damiano Rizzoni et al.

Summary: The structural and functional alterations of microvessels are closely associated with physiological aging and cardiometabolic diseases. Various methods, including micromyography and strain-gauge venous plethysmography, have been used to evaluate microvascular structure and endothelial function. Recently, noninvasive methods have been proposed to broaden the assessment of microvessels. However, more research is needed to confirm the predictive value of these methods.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Catheter-based ultrasound renal denervation in patients with resistant hypertension: the randomized, controlled REQUIRE trial

Kazuomi Kario et al.

Summary: This study found no significant difference in ambulatory blood pressure reductions between renal denervation and a sham procedure in treated patients with resistant hypertension. Although the blood pressure reduction after renal denervation was similar to other sham-controlled studies, the unexpected greater reduction in the sham control group in this study highlights design issues that will be addressed in a new trial.

HYPERTENSION RESEARCH (2022)

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Article Clinical Neurology

J-shape relation of blood pressure reduction and outcome in acute intracerebral hemorrhage: A pooled analysis of INTERACT2 and ATACH-II individual participant data

Xia Wang et al.

Summary: This study found that moderate rapid reductions in systolic blood pressure (SBP) in patients with acute intracerebral hemorrhage (ICH) are associated with improved functional outcomes, but large SBP reductions within 1 hour (e.g. from > 200 to target < 140 mmHg) are associated with a reduction or reversal of such benefits.

INTERNATIONAL JOURNAL OF STROKE (2022)

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Article Cardiac & Cardiovascular Systems

Statin treatment reduces the risk of death among elderly frail patients: evidence from a large population-based cohort

Federico Rea et al.

Summary: This study aimed to assess the protective effect of statins in a large cohort of frail elderly subjects. The findings showed that adherence to statin treatment reduced the risk of all-cause mortality and cardiovascular mortality. However, the benefit of statin treatment may be lower in frail elderly patients compared to those in good clinical conditions.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Treatment of Resistant Hypertension With Endovascular Baroreflex Amplification

Monique E. A. M. van Kleef et al.

Summary: This study aimed to evaluate the long-term safety and effectiveness of endovascular baroreflex amplification (EVBA) from both European and American CALM-FIM cohorts. The results showed that EVBA with MobiusHD effectively reduced blood pressure at the 3-year follow-up and had an acceptable safety profile during the implantation process.

JACC-CARDIOVASCULAR INTERVENTIONS (2022)

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Article Medicine, General & Internal

Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes The STEP 8 Randomized Clinical Trial

Domenica M. Rubino et al.

Summary: In overweight or obese adults without diabetes, once-weekly subcutaneous semaglutide resulted in significantly greater weight loss compared to once-daily subcutaneous liraglutide when added to counseling for diet and physical activity over 68 weeks.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Peripheral Vascular Disease

Potential impact of systematic and random errors in blood pressure measurement on the prevalence of high office blood pressure in the United States

Swati Sakhuja et al.

Summary: This study aimed to investigate the impact of measuring systolic and diastolic blood pressure with systematic bias and/or random error on the classification of high blood pressure in US adults. The study found that this measurement method may result in a significant proportion of misclassification of high blood pressure in US adults.

JOURNAL OF CLINICAL HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Cardiovascular mortality risk in young adults with isolated systolic hypertension: findings from population-based MONICA/KORA cohort study

Atasoy Seryan et al.

Summary: The study found that isolated systolic hypertension in young adults is associated with an increased risk of cardiovascular disease mortality, particularly affecting men. However, antihypertensive medication and increasing height have independently protective effects against CVD mortality, indicating that these factors should be considered in treatment rationale.

JOURNAL OF HUMAN HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Do recent meta-analyses truly prove that treatment with blood pressure-lowering drugs is beneficial at any blood pressure value, no matter how low? A critical review

Reinhold Kreutz et al.

Summary: Current European guidelines for hypertension favor a treatment threshold at a SBP level of 140 mmHg or above, but recent meta-analyses suggest potential benefits of BP-lowering across different ranges, challenging the current definition of hypertension.

JOURNAL OF HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Initial combination therapy for hypertension in patients of African ancestry: a systematic review and meta-analysis

Lizzy M. Brewster et al.

Summary: This study systematically reviewed randomized controlled trials on the effect of initial dual antihypertensive combination treatment in hypertensive African ancestry adults. The findings suggest that CCB + ACEI is more suitable than HCT + ACEI as the first-line initial combination therapy.

JOURNAL OF HYPERTENSION (2022)

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Review Clinical Neurology

Early lowering of blood pressure after acute intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data

Tom J. Moullaali et al.

Summary: Interventions to lower blood pressure within 7 days of intracerebral hemorrhage onset were effective in reducing bleeding, but did not show overall benefit on functional recovery. The treatment effect varied according to strategy and agent.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2022)

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Review Urology & Nephrology

Diagnosis and treatment of arterial hypertension 2021

Christian Ott et al.

Summary: In the past 4 years, guidelines for the management of arterial hypertension have been published with mostly concordant recommendations but some discordant opinions. Accurate blood pressure measurement is crucial for diagnosis, and out-of-office measurements are also important. Simplified antihypertensive drug treatment and personalized goals are emphasized. Renal denervation is supported for uncontrolled and treatment-resistant hypertension.

KIDNEY INTERNATIONAL (2022)

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Article Medicine, General & Internal

Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials

Qingyang Shi et al.

Summary: This study summarised the latest evidence on the benefits and harms of weight-lowering drugs. The findings suggest that the combination of phentermine-topiramate and GLP-1 receptor agonists is the most effective, with semaglutide potentially being the most effective GLP-1 receptor agonist.

LANCET (2022)

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Article Biochemistry & Molecular Biology

Long-term cardiovascular outcomes of COVID-19

Yan Xie et al.

Summary: Individuals with COVID-19, even those who were not hospitalized during the acute phase of the infection, are at an increased long-term risk of various cardiovascular disorders. A study using national healthcare databases found that beyond the first 30 days after infection, individuals with COVID-19 have an elevated risk of developing cerebrovascular disorders, heart diseases, and other cardiovascular complications. The risk increases depending on the care setting during the acute phase.

NATURE MEDICINE (2022)

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Article Clinical Neurology

Blood Pressure After Endovascular Thrombectomy and Outcomes in Patients With Acute Ischemic Stroke An Individual Patient Data Meta-analysis

Aristeidis H. Katsanos et al.

Summary: Increased blood pressure after endovascular thrombectomy (EVT) is associated with worse clinical outcomes in patients with acute ischemic stroke (AIS).

NEUROLOGY (2022)

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Article Public, Environmental & Occupational Health

The COVID-19 Pandemic and Access to Selected Ambulatory Care Services Among Populations With Severely Uncontrolled Diabetes and Hypertension in Massachusetts

Victoria M. Nielsen et al.

Summary: The outbreak of COVID-19 in Massachusetts resulted in reduced ambulatory care for patients with severely uncontrolled diabetes and hypertension, leading to significant declines in HbA(1c) testing and blood pressure monitoring. Although telehealth use increased during the pandemic, it was not equitable across subpopulations. Ensuring access and implementing hybrid telehealth models can minimize disruptions in care.

PUBLIC HEALTH REPORTS (2022)

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Review Medicine, General & Internal

NHS Health Check programme: a rapid review update

L. Tanner et al.

Summary: This study provides an updated review of the NHS Health Check programme, showing that it is associated with increased detection of cardiovascular disease risk factors and diagnoses. Women, individuals aged >= 60 years, and those from more socioeconomically advantaged backgrounds are more likely to participate in the programme.

BMJ OPEN (2022)

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Article Medicine, General & Internal

Risk of persistent and new clinical sequelae among adults aged 65 years and older during the post-acute phase of SARS-CoV-2 infection: retrospective cohort study

Ken Cohen et al.

Summary: A retrospective cohort study found that adults aged 65 and older face an increased risk of persistent and new clinical sequelae after acute infection with SARS-CoV-2, with respiratory failure, dementia, and post-viral fatigue being the most common sequelae.

BMJ-BRITISH MEDICAL JOURNAL (2022)

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Article Public, Environmental & Occupational Health

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease 2019

Emma Nichols et al.

Summary: With projected trends in population ageing and growth, the number of people with dementia is expected to increase. Understanding the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritization, with a focus on potentially modifiable risk factors.

LANCET PUBLIC HEALTH (2022)

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Article Urology & Nephrology

The ERA Registry Annual Report 2019: summary and age comparisons

Rianne Boenink et al.

Summary: This study collected data on renal replacement therapy (RRT) for end-stage renal disease from European and Mediterranean countries. It analyzed the incidence and prevalence of RRT, kidney transplantation activity, and survival probabilities. The study also compared different age categories and found significant differences.

CLINICAL KIDNEY JOURNAL (2022)

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Article Urology & Nephrology

Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against haemodialysis patients

Maria Korogiannou et al.

Summary: This study compared the full ambulatory blood pressure profile and short-term blood pressure variability in kidney transplant recipients (KTRs) versus hemodialysis (HD) patients. The results showed that KTRs had significantly lower systolic blood pressure (SBP), pulse-pressure (PP) levels, and blood pressure variability compared to HD patients during all periods studied.

CLINICAL KIDNEY JOURNAL (2022)

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Article Medicine, General & Internal

Association of Antihypertensives That Stimulate vs Inhibit Types 2 and 4 Angiotensin II Receptors With Cognitive Impairment

Zachary A. Marcum et al.

Summary: The use of antihypertensive medications that stimulate type 2 and 4 angiotensin II receptors is associated with a lower risk of dementia. This study examines the impact of exclusively stimulating vs inhibiting antihypertensive medication regimens on mild cognitive impairment (MCI) or dementia. The findings suggest that prevalent users of stimulating medications had lower rates of cognitive impairment.

JAMA NETWORK OPEN (2022)

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Review Cardiac & Cardiovascular Systems

Isolated Diastolic Hypertension and Risk of Cardiovascular Events: A Systematic Review and Meta-Analysis of Cohort Studies With 489,814 Participants

Mingyan Huang et al.

Summary: This meta-analysis demonstrates that isolated diastolic hypertension (IDH), as defined by the 2018 ESC criterion, is significantly associated with an increased risk of composite cardiovascular events, cardiovascular mortality, all strokes (including ischemic and hemorrhagic stroke), and hemorrhagic stroke specifically. However, IDH is not significantly associated with all-cause mortality and ischemic stroke. Subgroup analysis further reveals that the association between IDH and composite cardiovascular events is significant in younger adults and Asians, but not in elderly patients, Americans, and Europeans.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Stage 1 hypertension, sex, and acute coronary syndromes during midlife: the Hordaland Health Study

Ester Kringeland et al.

Summary: This study found that stage 1 hypertension is a stronger risk factor for acute coronary syndromes (ACS) in women than in men.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

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Review Peripheral Vascular Disease

Sleep Apnea and Hypertension

Gino Seravalle et al.

Summary: Obstructive sleep apnea is frequently found in clinical practice, especially with the increase in obesity and awareness of sleep-disordered breathing as a potential and treatable risk factor for cardiovascular diseases. Studies have shown the benefits of continuous positive airway pressure on daytime blood pressure and cardiovascular risk in patients with obstructive sleep apnea.

HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION (2022)

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Article Peripheral Vascular Disease

Is Medication Adherence Predictive of Cardiovascular Outcomes and Blood Pressure Control? The Systolic Blood Pressure Intervention Trial (SPRINT)

Stephen P. Glasser et al.

Summary: This study aimed to investigate the relationship between medication adherence measured using MMAS-8 and cardiovascular outcomes in the SPRINT trial. The results showed that medication adherence was not associated with the primary composite endpoint or blood pressure control. However, low adherence was associated with higher levels of certain physiological indicators.

AMERICAN JOURNAL OF HYPERTENSION (2022)

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Article Urology & Nephrology

A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease

Cynthia Delgado et al.

Summary: The National Kidney Foundation and the American Society of Nephrology have made recommendations regarding the consideration of race in GFR estimation. They suggest implementing the CKD-EPI creatinine equation without the race variable in all US laboratories and promoting the use of cystatin C for more accurate estimation. They also encourage research on new filtration markers and interventions to eliminate racial disparities. The unified approach should be adopted nationwide.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

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Article Urology & Nephrology

Atherosclerotic Renovascular Disease: A KDIGO (Kidney Disease: Improving Global Outcomes) Controversies Conference

Caitlin W. Hicks et al.

Summary: The diagnosis and management of atherosclerotic renovascular disease (ARVD) is complex and controversial. Despite studies showing that percutaneous renal artery revascularization does not improve major outcomes, medical therapy has evolved and is now considered the primary means of treating hypertension in ARVD.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

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Article Cardiac & Cardiovascular Systems

Trends of blood pressure control in the US during the COVID-19 pandemic

Nishant P. Shah et al.

Summary: This study aimed to understand whether home blood pressure (BP) control worsened during COVID-19 in the United States. The results showed that despite increased utilization of home monitoring, there was a modest rise in mean monthly BP during COVID-19.

AMERICAN HEART JOURNAL (2022)

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Editorial Material Urology & Nephrology

US Renal Data System 2021 Annual Data Report: Epidemiology of Kidney Disease in the United States

Kirsten L. Johansen et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2022)

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Editorial Material Peripheral Vascular Disease

Hypertension in older patients: a STEP forward?

Athanase Benetos et al.

BLOOD PRESSURE (2022)

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Editorial Material Peripheral Vascular Disease

Mild chronic hypertension in pregnancy: to treat or wait?

Costas Thomopoulos et al.

BLOOD PRESSURE (2022)

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Article Peripheral Vascular Disease

Covid-19 associated reduction in hypertension-related diagnostic and therapeutic procedures in Excellence Centers of the European Society of Hypertension

Thomas Weber et al.

Summary: The Covid-19 pandemic led to a significant decrease in non-Covid-19 related hypertension care procedures. The first wave and lockdown period saw the largest reduction in diagnostic and therapeutic procedures related to hypertension. The long-term consequences on blood pressure control and cardiovascular events need further investigation.

BLOOD PRESSURE (2022)

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Article Pharmacology & Pharmacy

Psoriasis risk after beta-blocker exposure: Description of a pharmacovigilance signal

Brahim Azzouz et al.

Summary: The aim of this study was to investigate French pharmacovigilance data and characterize psoriatic conditions that occurred after beta-blocker (BB) exposure. The study found a total of 225 cases of psoriatic conditions after BB exposure, involving both different types of BBs and with hypertension as the main therapeutic indication. The mean time to onset was 5 months and about 68% of cases showed improvement after discontinuing BBs.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2022)

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Review Cardiac & Cardiovascular Systems

Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association

Craig J. Beavers et al.

Summary: In the population of cardio-oncology, drug interactions play a significant role due to the complexity of drugs and potential risks. It is important for clinicians to recognize potential drug-drug interactions to minimize risks in cardiovascular or cancer therapies. This scientific statement provides an overview of pharmacodynamic and pharmacokinetic drug interactions for clinicians treating cancer patients exposed to common cardiovascular and cancer medications.

CIRCULATION (2022)

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Article Cardiac & Cardiovascular Systems

Use of fixed-dose combination antihypertensives in Germany between 2016 and 2020: an example of guideline inertia

Felix Mahfoud et al.

Summary: The study found that the recommendations for hypertension treatment in the 2018 ESC/ESH guidelines were underutilized in clinical practice, with a decreasing trend in the prescription of FDC products over the years.

CLINICAL RESEARCH IN CARDIOLOGY (2022)

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Review Peripheral Vascular Disease

An Update on Refractory Hypertension

Faris Matanes et al.

Summary: Refractory hypertension (RfHTN) refers to the condition where blood pressure remains uncontrolled despite using at least 5 different classes of antihypertensive medications, including a long-acting thiazide diuretic and a mineralocorticoid receptor antagonist (MRA) at maximal or maximally tolerated doses. Unlike resistant hypertension (RHTN), RfHTN is largely caused by increased sympathetic activity and is associated with a higher prevalence of target organ damage.

CURRENT HYPERTENSION REPORTS (2022)

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Article Public, Environmental & Occupational Health

Psychosocial work factors and blood pressure among 63 800 employees from The Netherlands in the Lifelines Cohort Study

Md Omar Faruque et al.

Summary: This study investigated the association between psychosocial work factors and blood pressure in a large general working population in the Netherlands. The results showed that high job strain and effort-reward imbalance were associated with higher blood pressure, while emotional demands were associated with lower blood pressure.

JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2022)

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Review Peripheral Vascular Disease

Individualized Beta-Blocker Treatment for High Blood Pressure Dictated by Medical Comorbidities: Indications Beyond the 2018 European Society of Cardiology/European Society of Hypertension Guidelines

Giuseppe Mancia et al.

Summary: Several hypertension guidelines have downgraded beta-blockers as first-choice drugs for hypertension treatment, but this may not be justified by available evidence. Beta-blockers effectively lower blood pressure and have solid documentation in preventing cardiovascular complications. Suspected inconveniences of beta-blockers may have been overemphasized, while patients with certain conditions can benefit from beta-blocker therapy. Beta-blockers are pathophysiologically appropriate for hypertension treatment due to the activation of the sympathetic nervous system. They also have favorable effects on various clinical conditions that coexist with hypertension. However, selecting beta-blockers with documented effects is important in guidelines.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Risk Stratification by Cross-Classification of Central and Brachial Systolic Blood Pressure

Yi-Bang Cheng et al.

Summary: This study investigated the relationship between cardiovascular risk and central and brachial systolic pressure and proposed thresholds to differentiate hypertension from normal blood pressure. Regardless of brachial blood pressure status, central hypertension was associated with increased cardiovascular and cerebrovascular risk, highlighting the importance of controlling central hypertension.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Hypertension-Mediated Organ Damage: Prevalence, Correlates, and Prognosis in the Community

Ramachandran S. Vasan et al.

Summary: This study examined the prevalence, correlates, and prognosis of hypertension-mediated organ damage (HMOD) in a community-based study. The findings showed that the prevalence of HMOD varied across different blood pressure guidelines and that the presence of HMOD increased the risk of cardiovascular disease.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Methodological Aspects of Meta-Analyses Assessing the Effect of Blood Pressure-Lowering Treatment on Clinical Outcomes

Mattias Brunstrom et al.

Summary: This review provides an overview of important methodological considerations for systematic reviews and meta-analyses, particularly focusing on the effect of blood pressure-lowering on clinical outcomes. It also discusses the pros and cons of different analytical strategies.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Microcirculation and Macrocirculation in Hypertension: A Dangerous Cross-Link?

Stephane Laurent et al.

Summary: Microcirculation and macrocirculation form a dangerous cross-link in hypertension, leading to vessel damage and elevated blood pressure. This vicious cycle can be reversed through pharmacological treatment.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Central versus ambulatory blood pressure for predicting mortality and cardiovascular events in hemodialysis patients: a multicenter cohort study

Wenjin Liu et al.

Summary: Central blood pressure is predictive of all-cause mortality and cardiovascular events in dialysis patients, but its prognostic value does not outperform ambulatory peripheral blood pressure.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Urine N-acetyl-Ser-Asp-Lys-Pro measurement as a versatile biomarker to assess adherence to angiotensin-converting enzyme inhibitors

Benjamin Kably et al.

Summary: Urinary measurement of AcSDKP can serve as a reliable method for assessing adherence to ACEI treatment, showing good consistency and correlation with ACEI metabolite concentrations.

JOURNAL OF HYPERTENSION (2022)

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Article Medicine, General & Internal

Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy The BUMP 1 Randomized Clinical Trial

Katherine L. Tucker et al.

Summary: The use of blood pressure self-monitoring with telemonitoring did not lead to significantly earlier detection of hypertension in pregnant individuals at higher risk of preeclampsia, compared to usual care.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Medicine, General & Internal

Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension The BUMP 2 Randomized Clinical Trial

Lucy C. Chappell et al.

Summary: Among individuals with pregnancy hypertension, blood pressure self-monitoring did not lead to significantly improved clinic-based blood pressure control.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Medicine, General & Internal

Screening for Primary Open-Angle Glaucoma

Jill Jin

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Cardiac & Cardiovascular Systems

Effects of Transcendental Meditation on Blood Pressure A Meta-analysis

Joanne Kraenzle Schneider et al.

Summary: This study quantitatively synthesized the effects of transcendental meditation (TM) on blood pressure and found that it mildly reduced blood pressure, but the effects waned after 3 months. It was more beneficial for adults older than 65 years compared to younger adults.

JOURNAL OF CARDIOVASCULAR NURSING (2022)

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Article Peripheral Vascular Disease

Virtual management of hypertension: lessons from the COVID-19 pandemic-International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension

Nadia A. Khan et al.

Summary: The COVID-19 pandemic has led to a shift from in person care to virtual care, and virtual management of hypertension is likely to continue. The International Society of Hypertension has provided practical guidance on virtual management of hypertension to improve diagnosis and blood pressure control.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Nebivolol and incident cardiovascular events in hypertensive patients compared with nonvasodilatory beta blockers

Daniel M. Huck et al.

Summary: Compared with nonvasodilatory beta blockers, the vasodilatory beta blocker nebivolol is associated with reduced incidence of cardiovascular events.

JOURNAL OF HYPERTENSION (2022)

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Article Cardiac & Cardiovascular Systems

Association of Cumulative Blood Pressure With Cognitive Decline, Dementia, and Mortality

Chenglong Li et al.

Summary: Long-term cumulative blood pressure is associated with subsequent cognitive decline, dementia risk, and all-cause mortality, emphasizing the importance of blood pressure control for maintaining cognitive health.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Review Medicine, General & Internal

Effects of early-life poverty on health and human capital in children and adolescents: analyses of national surveys and birth cohort studies in LMICs

Cesar G. Victora et al.

Summary: The survival and nutrition of children and adolescents have significantly improved in the past two decades, but disparities still exist between and within countries. This study analyzes the relationship between the health, nutrition, and cognitive development of children and adolescents and early-life poverty using data from low-income and middle-income countries. Additionally, it shows the long-term impact of early-life poverty on health and human capital. Therefore, implementing comprehensive anti-poverty policies and programs is crucial, especially during the ongoing disruptions caused by COVID-19.

LANCET (2022)

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Article Medicine, General & Internal

Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial

Felix Mahfoud et al.

Summary: In this study, the long-term safety and efficacy of renal denervation were evaluated. The results showed that renal denervation produced a clinically meaningful and lasting blood pressure reduction up to 36 months, independent of concomitant antihypertensive medications and without major safety events.

LANCET (2022)

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Review Cardiac & Cardiovascular Systems

Blood pressure and its variability: classic and novel measurement techniques

Aletta E. Schutte et al.

Summary: This review outlines the advantages and disadvantages of conventional and novel methods for measuring average blood pressure levels and blood pressure variability. It also discusses the potential utility of these methods in improving the treatment and management of patients with hypertension.

NATURE REVIEWS CARDIOLOGY (2022)

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Article Medicine, General & Internal

Treatment for Mild Chronic Hypertension during Pregnancy

A. T. Tita et al.

Summary: In pregnant women with mild chronic hypertension, a strategy of targeting a blood pressure of less than 140/90 mm Hg was associated with better pregnancy outcomes compared to a strategy of reserving treatment only for severe hypertension, without increasing the risk of small-for-gestational-age birth weight.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

Exercise intensity assessment and prescription in cardiovascular rehabilitation and beyond: why and how: a position statement from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology

Dominique Hansen et al.

Summary: The proper determination of exercise intensity is crucial for the rehabilitation of patients with cardiovascular disease, as it affects the effectiveness and safety of exercise training. Various organizations have published position statements on aerobic exercise intensity assessment and prescription in cardiovascular rehabilitation. Subsequent research has highlighted controversies and refinements in commonly applied concepts related to exercise intensity determination in cardiovascular rehabilitation.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Long Term Prognostic Impact of Sex-specific Longitudinal Changes in Blood Pressure. The EPIC-Norfolk Prospective Population Cohort Study

Tiberiu A. Pana et al.

Summary: This study aimed to determine the sex differences in blood pressure trajectories in mid-life and their associations with mortality and incident cardiovascular disease (CVD) in old age. The results showed that women had lower systolic blood pressure (SBP) trajectories compared to men, and women also had lower mortality and CVD incidence. Hypertensive trajectories were associated with increased mortality and incident CVD, but these associations were not maintained after adjusting for confounding factors including antihypertensive therapies.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Renal Artery Stenting in Consecutive High-Risk Patients With Atherosclerotic Renovascular Disease: A Prospective 2-Center Cohort Study

Mark Reinhard et al.

Summary: In this prospective cohort study, renal artery stenting was found to reduce blood pressure and antihypertensive medication usage, increase estimated glomerular filtration rate, and decrease hospital admissions due to heart failure/sudden pulmonary edema in high-risk patients with severe renal artery stenosis.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Editorial Material Cardiac & Cardiovascular Systems

Malignant Hypertension: Current Perspectives and Challenges

Romain Boulestreau et al.

Summary: There are significant knowledge gaps regarding the pathogenesis and treatment of malignant hypertension. This review aims to summarize current viewpoints and challenges, with the goal of pooling future efforts to improve treatment and prognosis of malignant hypertension.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Review Cardiac & Cardiovascular Systems

Renin-Angiotensin Aldosterone System Inhipitors and COVID-19: A Systematic Review and Meta-Analysis Revealing Critical Bias Across a Body of Observational Research

Jordan Loader et al.

Summary: This study evaluated the association between RAAS inhibitors and COVID-19 and revealed significant biases in COVID-19 research. The findings suggest that patients using RAAS inhibitors have a lower risk of hospitalization and intubation or death from COVID-19, but these protective effects may not be clinically significant.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Review Medicine, General & Internal

Cardiovascular Disease Risk in Rheumatoid Arthritis Anno 2022

Bas Dijkshoorn et al.

Summary: RA patients have a 1.5 times higher risk of developing cardiovascular diseases compared to the general population. This is partly due to systemic inflammation causing increased atherogenesis, and an increased prevalence of traditional cardiovascular risk factors.

JOURNAL OF CLINICAL MEDICINE (2022)

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Review Urology & Nephrology

Assessment of hypertension in kidney transplantation by ambulatory blood pressure monitoring: a systematic review and meta-analysis

Anna Pisano et al.

Summary: In kidney transplant recipients, ambulatory blood pressure monitoring revealed a high proportion of uncontrolled hypertension, masked hypertension, and white-coat hypertension. These results suggest that hypertension is inadequately diagnosed and controlled by office blood pressure recordings in this population, and the high prevalence of non-dippers indicates disrupted circadian rhythm in these patients.

CLINICAL KIDNEY JOURNAL (2022)

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Review Public, Environmental & Occupational Health

Work Exposures and Development of Cardiovascular Diseases: A Systematic Review

Christian Moretti Anfossi et al.

Summary: This study systematically reviewed observational studies on adults exposed to job strain, effort-reward imbalance, long working hours, job insecurity, shift work, and occupational noise, and assessed their association with cardiovascular diseases (CVDs). The findings provided sufficient evidence of a harmful relationship between job strain, shift work, and CVDs. However, more high-quality studies are needed for the other work exposures.

ANNALS OF WORK EXPOSURES AND HEALTH (2022)

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Article Public, Environmental & Occupational Health

Alcohol and Health Outcomes: An Umbrella Review of Meta-Analyses Base on Prospective Cohort Studies

Lixian Zhong et al.

Summary: An umbrella review of meta-analyses on the association between alcohol consumption and health outcomes found that while there were statistically significant beneficial associations and harmful associations, only a small number of them had high-quality evidence. Further robust and larger prospective studies are needed to confirm these results.

FRONTIERS IN PUBLIC HEALTH (2022)

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Article Medicine, General & Internal

Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease

Kiran J. Biddinger et al.

Summary: Observational studies have suggested cardiovascular benefits associated with light alcohol consumption, while genetic analyses have indicated a possible causal link between alcohol intake and increased cardiovascular disease risk. This cohort study using the UK Biobank examined the association of habitual alcohol intake with cardiovascular disease risk, showing that light to moderate alcohol consumption was associated with healthier lifestyle factors, but genetic predisposition to alcohol intake was associated with increased risk of hypertension and coronary artery disease across different levels of intake.

JAMA NETWORK OPEN (2022)

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Article Medicine, General & Internal

Association of Nighttime Masked Uncontrolled Hypertension With Left Ventricular Hypertrophy and Kidney Function Among Patients with Chronic Kidney Disease Not Receiving Dialysis

Xiaocen Fu et al.

Summary: Nighttime MUCH is common in patients with hypertension and nondialysis CKD, and is associated with LVH and poor kidney outcomes. There is insufficient use of ambulatory blood pressure monitoring in this patient population.

JAMA NETWORK OPEN (2022)

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Article Clinical Neurology

European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack

Jesse Dawson et al.

Summary: The European Stroke Organisation (ESO) guideline provides evidence-based recommendations on pharmacological management for the prevention of recurrent stroke and other important outcomes after ischaemic stroke or transient ischaemic attack. The guideline covers areas such as blood pressure, diabetes mellitus, lipid levels, and antiplatelet therapy, aiming to reduce the long-term risk of recurrent stroke.

EUROPEAN STROKE JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Cardiovascular Risk Reduction After Renal Denervation According to Time in Therapeutic Systolic Blood Pressure Range

Felix Mahfoud et al.

Summary: This study aimed to evaluate the impact of radiofrequency renal denervation (RDN) on time in therapeutic range (TTR) and its association with cardiovascular outcomes. The results showed sustained blood pressure reductions and higher TTR through 36 months after RDN. A 10% increase in TTR through 6 months was associated with significant risk reductions in major cardiovascular events from 6 to 36 months.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

The occurrence of drug-induced side effects in women and men with arterial hypertension and comorbidities

Magdalena Polaczyk et al.

Summary: This study found that women reported adverse drug reactions more frequently, with the risk increasing with age and the presence of respiratory diseases. In men, the risk of adverse drug reactions was mainly influenced by hypercholesterolemia or other metabolic diseases.

KARDIOLOGIA POLSKA (2022)

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Article Medicine, General & Internal

Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial

Markus P. Schlaich et al.

Summary: This study evaluated the blood pressure lowering efficacy of the dual endothelin antagonist aprocitentan in patients with resistant hypertension. The results showed that aprocitentan had a blood pressure lowering effect at week 4 and maintained a sustained effect at week 40. The most common adverse event was mild-to-moderate edema or fluid retention.

LANCET (2022)

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Article Medicine, General & Internal

Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials

Natalie Staplin et al.

Summary: This study provides evidence that SGLT2 inhibitors can reduce the risk of kidney disease progression and acute kidney injury, not only in patients with type 2 diabetes at high cardiovascular risk, but also in patients with chronic kidney disease or heart failure regardless of diabetes status, primary kidney disease, or kidney function.

LANCET (2022)

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Review Medicine, General & Internal

Regular physical activity: a major component of isolated systolic hypertension in the young

Paolo Palatini

Summary: This article discusses the epidemiology and pathophysiology of isolated systolic hypertension in youth (ISHY) with a focus on its relationship with aerobic exercise. Regular physical activity has been shown to have positive effects on cardiovascular health in young individuals, improving arterial elasticity. Recent studies indicate that long-term aerobic sports training is a main factor contributing to the development of ISHY. Athletes with ISHY should undergo comprehensive cardiovascular risk assessment before participating in competitive athletics.

MINERVA MEDICA (2022)

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Article Nutrition & Dietetics

Causal associations of alcohol consumption with cardiovascular diseases and all-cause mortality among Chinese males

Chunyu Hu et al.

Summary: This study finds a causal relationship between alcohol consumption and cardiovascular diseases (CVDs) and all-cause mortality in Chinese males. Light and moderate drinking can reduce the risk of CVDs and all-cause mortality. However, genetically predicted alcohol consumption shows a linear association with CVDs.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)

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Article Medicine, General & Internal

Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events

Areef Ishani et al.

Summary: A study found that there was little difference in the prevention of major adverse cardiovascular events between chlorthalidone and hydrochlorothiazide in elderly patients with hypertension.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Editorial Material Peripheral Vascular Disease

Masked hypertension in type 2 diabetes: never take normotension for granted and always assess out-of-office blood pressure

Krzysztof Narkiewicz et al.

BLOOD PRESSURE (2022)

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Editorial Material Peripheral Vascular Disease

Single-pill combinations, hypertension control and clinical outcomes: potential, pitfalls and solutions

Brent M. Egan et al.

BLOOD PRESSURE (2022)

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Article Multidisciplinary Sciences

Primary hypertension, anti-hypertensive medications and the risk of severe COVID-19 in UK Biobank

Holly Pavey et al.

Summary: Hypertension is an important risk factor for severe COVID-19. Individuals with hypertension have a higher risk of developing severe COVID-19 compared to those without hypertension. The level of systolic blood pressure and the type of anti-hypertensive medication used are also related to the risk of severe COVID-19.

PLOS ONE (2022)

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Review Peripheral Vascular Disease

Machine Learning for Hypertension Prediction: a Systematic Review

Gabriel F. S. Silva et al.

Summary: This review provides an overview of using machine learning algorithms to predict hypertension. The screening process identified 21 articles published between January 2018 and May 2021, and the comparison showed that support vector machines, extreme gradient boosting, and random forest algorithms performed well. Machine learning algorithms have the potential to improve preventive clinical decisions and public health policies, but technical factors such as outcome definition, code availability, predictive performance, explainability, and data leakage need to be consistently evaluated.

CURRENT HYPERTENSION REPORTS (2022)

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Article Cardiac & Cardiovascular Systems

Hypertension in children and adolescents A consensus document from ESC Council on Hypertension, European Association of Preventive Cardiology, European Association of Cardiovascular Imaging, Association of Cardiovascular Nursing & Allied Professions, ESC Council for Cardiology Practice and Association for European Paediatric and Congenital Cardiology

Giovanni de Simone et al.

Summary: The definition and management of arterial hypertension in children and adolescents are uncertain. The European Society of Cardiology task-force has produced a Consensus Document to address various aspects of hypertension in this age group and highlight areas for further research and successful implementation.

EUROPEAN HEART JOURNAL (2022)

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Article Peripheral Vascular Disease

Higher Arm Versus Lower Arm Systolic Blood Pressure and Cardiovascular Outcomes: a Meta-Analysis of Individual Participant Data From the INTERPRESS-IPD Collaboration

Christopher E. Clark et al.

Summary: The study found that using blood pressure readings from the higher arm instead of the lower arm can more accurately diagnose and manage hypertension. Models based on higher arm BP performed better in predicting cardiovascular events and resulted in a higher reclassification rate of participants.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Day to Day Blood Pressure Variability Associated With Cerebral Arterial Dilation and White Matter Hyperintensity

Boyu Zhang et al.

Summary: The study found a correlation between blood pressure variability (BPV) and white matter hyperintensity (WMH) volume as well as cerebral arterial dilation. Periventricular WMH showed a stronger association with BPV. Increased BPV may be independently associated with small vessel disease and contribute to intracranial arterial dilation. Therefore, managing BPV may be an important target for preserving cerebrovascular health.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

Tanika N. Kelly et al.

Summary: This study conducted a multiancestry whole-genome sequencing analysis to explore the associations between coding and noncoding variants and blood pressure. The study identified two significant blood pressure signals and nineteen suggestive signals, providing insights for future blood pressure sequencing studies, including the use of aggregate analyses and the need for larger, diverse samples and family studies.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Reproducibility of blood pressure phenotypes identified by office and ambulatory blood pressure in treated hypertensive patients. Data from the PHYLLIS study

Giuseppe Mancia et al.

Summary: Previous studies have found poor reproducibility in white-coat hypertension and masked uncontrolled hypertension, as well as different nighttime blood pressure patterns. This phenomenon does not seem to be dependent on the type of antihypertensive treatment used.

HYPERTENSION RESEARCH (2022)

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Letter Medicine, General & Internal

Association Between Vaccination and Acute Myocardial Infarction and Ischemic Stroke After COVID-19 Infection

Young-Eun Kim et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

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Article Peripheral Vascular Disease

Prevalence and associated factors of obstructive sleep apnea in refractory hypertension

Bernardo Chedier et al.

Summary: This study describes the prevalence of obstructive sleep apnea (OSA) and polysomnography (PSG) pattern in patients with refractory hypertension (RfHT). Patients with RfHT have similar OSA prevalence compared to patients with resistant hypertension, but they are younger and have a better sleep pattern.

JOURNAL OF HYPERTENSION (2022)

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Editorial Material Peripheral Vascular Disease

A reverse translational pharmacological approach to understand the underlying mechanisms of the reported association between hydrochlorothiazide and non-melanoma skin cancer

Elisabetta Bigagli et al.

JOURNAL OF HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Effect of different treatments for obstructive sleep apnoea on blood pressure

Chengkun Kou et al.

Summary: MRAs and ACEIs/ARBs are effective in lowering blood pressure in OSA patients, RDN is a novel hypertension treatment, and CPAP has a mild but stable effect on reducing blood pressure.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Home blood pressure monitoring schedule: optimal and minimum based on 2122 individual participants' data

Konstantinos G. Kyriakoulis et al.

Summary: This study aimed to investigate the optimal and minimum schedule for home blood pressure monitoring. The results suggest that monitoring for 7 days with a minimum of 3 days is recommended, and the readings from the first day should be discarded.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Diagnosis and management of hypertension in patients with Cushing's syndrome: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension

Francesco Fallo et al.

Summary: Cushing's syndrome, characterized by excessive cortisol levels, leads to systemic manifestations and increased cardiovascular risk, particularly hypertension. Early diagnosis and tailored management are crucial in mitigating the negative effects of Cushing's syndrome, including addressing the underlying cause and using individualized antihypertensive drugs. A consensus document prepared by experts in endocrine hypertension provides a summary of the latest knowledge on the epidemiology, genetics, diagnosis, and treatment of hypertension in Cushing's syndrome.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Cuffless blood pressure measuring devices: review and statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability

George S. Stergiou et al.

Summary: Cuffless blood pressure devices have the potential to change the diagnosis and management of hypertension, but fundamental questions regarding accuracy, performance, and implementation need to be addressed before recommending them for clinical use.

JOURNAL OF HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Reproducibility of masked hypertension and office-based hypertension: a systematic review and meta-analysis

Christina Antza et al.

Summary: This study aimed to investigate the reproducibility of different blood pressure phenotypes over time and their accuracy in representing the patients' blood pressure status. The results showed that masked hypertension had better reproducibility with ambulatory blood pressure monitoring (ABPM) than with home blood pressure monitoring (HBPM), while the reproducibility of office-based hypertension was low with both methods.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Use of initial and subsequent antihypertensive combination treatment in the last decade: analysis of a large Italian database

Laura Savare et al.

Summary: This study aimed to assess the use of antihypertensive combination treatment in a large Italian population. The findings show that the use of antihypertensive drug combinations is low in real-life settings and has not noticeably increased in recent years.

JOURNAL OF HYPERTENSION (2022)

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Article Cardiac & Cardiovascular Systems

Harmonization of the American College of Cardiology/ American Heart Association and European Society of Cardiology/ European Society of Hypertension Blood Pressure/Hypertension Guidelines

Paul K. Whelton et al.

Summary: The 2017 American College of Cardiology/American Heart Association and 2018 European Society of Cardiology/European Society of Hypertension guidelines for managing high blood pressure have significant influence. While there are differences in the recommended blood pressure cut points and treatment approach, overall there is substantial agreement between the two guideline-writing committees. Harmonization of future guidelines would enhance the commonality of their core recommendations and encourage better prevention, awareness, treatment, and control of hypertension worldwide.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Article Urology & Nephrology

Markers of Kidney Tubular Secretion and Risk of Adverse Events in SPRINT Participants with CKD

Alexander L. Bullen et al.

Summary: This study found that kidney tubular secretion function is associated with adverse events during hypertension treatment. Patients with poorer secretion function are more likely to experience serious adverse events such as acute kidney injury, electrolyte abnormalities, and hyperkalemia.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2022)

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Review Clinical Neurology

Diagnosis and treatment of orthostatic hypotension

Wouter Wieling et al.

Summary: Orthostatic hypotension is a condition where blood pressure significantly decreases upon standing, increasing the risk of adverse outcomes even without symptoms. Continuous blood pressure measurements have identified four major subtypes, and the clinical presentations can vary widely. Diagnosis requires careful history taking, physical examination, and blood pressure measurements. Management and prognosis depend on the underlying cause and may involve lifestyle measures, cessation of blood pressure lowering drugs, and pharmacological treatment in selected cases.

LANCET NEUROLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Effects of Renal Denervation vs Sham in Resistant Hypertension After Medication Escalation Prespecified Analysis at 6 Months of the RADIANCE-HTN TRIO Randomized Clinical Trial

Michel Azizi et al.

Summary: This study aims to evaluate the long-term effects and safety of ultrasound RDN for patients with resistant hypertension. The results show that after 2 months of treatment, both the uRDN group and the sham group had similar antihypertensive effects, but the uRDN group required fewer additional medications.

JAMA CARDIOLOGY (2022)

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Editorial Material Endocrinology & Metabolism

What's preventing us from curbing the obesity crisis?

[Anonymous]

LANCET DIABETES & ENDOCRINOLOGY (2022)

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Article Medicine, General & Internal

Prevalence of hypertension and associated risks in hospitalized patients with COVID-19: a meta-analysis of meta-analyses with 1468 studies and 1,281,510 patients

Yousof Khairy et al.

Summary: This study conducted a meta-analysis of the meta-analyses to estimate the prevalence and associated risks of hypertension in patients with COVID-19. The results indicated that hypertension is a common comorbid disease in hospitalized patients with COVID-19, which significantly increases mortality risk, the severity of the disease, and the probability of ICU admission. Being male is associated with higher disease severity and ICU admission risk.

SYSTEMATIC REVIEWS (2022)

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Article Multidisciplinary Sciences

Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records

Ellen J. Thompson et al.

Summary: The frequency and risk factors of long COVID in community-based individuals are unclear. A study analyzing data from 10 UK population-based studies and electronic health records found wide variation in the frequency of long COVID between studies, but identified some consistent risk factors.

NATURE COMMUNICATIONS (2022)

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Article Cardiac & Cardiovascular Systems

Concomitant Use of Diltiazem With Direct Oral Anticoagulants and Bleeding Risk in Atrial Fibrillation

Yunwen Xu et al.

Summary: This study evaluated the risk of bleeding in patients with atrial fibrillation who used diltiazem concurrently with direct oral anticoagulants (DOACs). The study found that concomitant use of diltiazem increased the risk of bleeding compared to DOACs alone. This risk was observed in both patients with and without chronic kidney disease.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Review Cardiac & Cardiovascular Systems

Racial Disparities in Cardiovascular Risk and Cardiovascular Care in Women

Rachel-Maria Brown et al.

Summary: Research on sex and gender aspects of cardiovascular disease has helped reduce cardiovascular mortality in women, but gender and racial biases, lack of representation in clinical trials, and undertreatment continue to contribute to disparities in outcomes among women of color. Understanding and addressing these disparities is crucial to improving cardiovascular care for racial and ethnic minority women.

CURRENT CARDIOLOGY REPORTS (2022)

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Review Cardiac & Cardiovascular Systems

Sensitivity and specificity of automated blood pressure devices to detect atrial fibrillation: A systematic review and meta-analysis of diagnostic accuracy

Edmond W. L. Tang et al.

Summary: This systematic review and meta-analysis examined the sensitivity and specificity of office and out-of-office automated blood pressure devices in detecting atrial fibrillation (AF). The results showed that office BP devices can be clinically used to screen for AF in high-risk populations. However, further studies are needed to determine the impact of AF screening using office BP devices on reducing stroke risk and mortality.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)

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Article Peripheral Vascular Disease

Health Professionals' Perceptions of Disparities in Hypertension Control: A Mixed Methods Study

Lizzy M. Brewster et al.

Summary: This exploratory study revealed that health professionals mainly attribute disparities in hypertension control to patient-level factors, and have lower awareness of disparities in more proximate healthcare settings. Therefore, addressing disparities in hypertension control needs to take into account the perceptions of health professionals.

AMERICAN JOURNAL OF HYPERTENSION (2022)

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News Item Peripheral Vascular Disease

Coffee and blood pressure: exciting news!

Claudio Borghi

Summary: A growing number of epidemiological studies have reported the beneficial effects of habitual coffee consumption on incident cardiovascular disease (CVD) and mortality. However, the effects of coffee on arterial hypertension are still objects of active discussion mainly because of the debated effects of caffeine on blood pressure and cardiovascular system. Recent evidence has been published excluding a significant effect of coffee consumption on hypertension development and blood pressure control in treated and untreated hypertensive, supporting a protective role for the antioxidant components of coffee that may counteract the claimed negative effect of caffeine.

BLOOD PRESSURE (2022)

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Review Peripheral Vascular Disease

Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified

Murray Esler et al.

Summary: Beta-blockers have solid documentation in preventing cardiovascular complications in hypertension and represent a heterogeneous class of drugs. They are a suitable treatment for hypertension based on the activation of the sympathetic nervous system and elevated heart rate. However, the downgrading of beta-blockers in the European hypertension guideline may not be justified.

BLOOD PRESSURE (2022)

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Article Cardiac & Cardiovascular Systems

Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales

Rochelle Knight et al.

Summary: Incidence of vascular diseases remains elevated up to 49 weeks after COVID-19 diagnosis, with a faster decline for arterial thromboses than VTEs. Patients hospitalized with COVID-19, non-White individuals, and those without previous events are at higher risk. Policies to prevent severe COVID-19, including vaccination, early post-discharge review, risk factor control, and secondary preventive agents, are supported by these findings.

CIRCULATION (2022)

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Letter Cardiac & Cardiovascular Systems

Chlorthalidone for Resistant Hypertension in Advanced Chronic Kidney Disease

Rajiv Agarwal et al.

CIRCULATION (2022)

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Review Cardiac & Cardiovascular Systems

The role of coronary artery calcium in allocating pharmacotherapy for primary prevention of cardiovascular disease: The ABCs of CAC

Yash Maniar et al.

Summary: Determining optimal candidates for primary prevention of atherosclerotic cardiovascular disease is challenging, but coronary artery calcium (CAC) scoring has shown potential value in refining risk assessment and guiding treatment decisions. CAC scoring can help allocate aspirin for primary prevention, determine blood pressure and cholesterol targets, and guide the use of expensive medications for diabetes. Elevated CAC scores, even greater than 400 or 1000, are associated with a risk for cardiovascular disease comparable to that of secondary prevention cohorts.

CLINICAL CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

Florian Kronenberg et al.

Summary: This consensus statement provides updated evidence on the role of Lp(a) in ASCVD and aortic valve stenosis, and offers clinical guidance on testing and treating elevated Lp(a) levels.

EUROPEAN HEART JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Sex differences in arterial hypertension A scientific statement from the ESC Council on Hypertension, the European Association of Preventive Cardiology, Association of Cardiovascular Nursing and Allied Professions, the ESC Council for Cardiology Practice, and the ESC Working Group on Cardiovascular Pharmacotherapy

Eva Gerdts et al.

Summary: Sex chromosomes and sex hormones play differential roles in blood pressure regulation and cardiovascular risk factors between females and males with essential arterial hypertension. The risk for cardiovascular disease is higher in females at lower blood pressure levels, suggesting the need for sex-specific thresholds in hypertension diagnosis. It is currently unknown if hypertension should be managed differently in females and males, highlighting the need for focused research on sex-specific prevention and management.

EUROPEAN HEART JOURNAL (2022)

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Article Cardiac & Cardiovascular Systems

Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis

Ruth Peters et al.

Summary: Observational studies have shown U-shaped associations between blood pressure (BP) and incident dementia in older age, but the results of BP-lowering treatment in hypertensive patients have been mixed. This study analyzed data from five randomized controlled trials to examine the effects of BP-lowering treatment on the prevention of dementia. The results showed that antihypertensive treatment reduced the risk of incident dementia, and the greater fall in BP was associated with a greater reduction in dementia risk.

EUROPEAN HEART JOURNAL (2022)

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Article Peripheral Vascular Disease

Home Blood Pressure Can Predict the Risk for Stroke/Bleeding Events in Elderly Patients With Nonvalvular Atrial Fibrillation From the ANAFIE Registry

Kazuomi Kario et al.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Changes in Blood Pressure Outcomes Among Hypertensive Individuals During the COVID-19 Pandemic: A Time Series Analysis in Three US Healthcare Organizations

Hiroshi Gotanda et al.

Summary: The COVID-19 pandemic has had a negative impact on blood pressure outcomes among individuals with hypertension, with an increase in blood pressure and a decrease in the proportion of controlled blood pressure. Opportunities for telemedicine and home blood pressure monitoring may mitigate adverse impacts in future disasters/emergencies.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Uric Acid and Hypertension: a Review of Evidence and Future Perspectives for the Management of Cardiovascular Risk

Claudio Borghi et al.

Summary: Uric acid is closely related to hypertension, and the mechanism of hyperuricemia-induced hypertension involves oxidative stress and intracellular urate activity, mainly through the activity of XOR. Urate-lowering treatment has a significant effect on blood pressure control, and future research should focus on identifying the relationship and clinical implications between serum uric acid and hypertension.

HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Blood pressure and Cardiorenal Outcomes With Finerenone in Chronic Kidney Disease in Type 2 Diabetes

Luis M. Ruilope et al.

Summary: This analysis explored the relationship between office systolic blood pressure (SBP) and cardiorenal outcomes with finerenone in FIDELIO-DKD trial. Finerenone significantly reduced office SBP across all baseline SBP quartiles and improved cardiorenal outcomes. Reductions in office SBP accounted for a small proportion of the treatment effect on cardiorenal outcomes.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Role of Uromodulin in Salt-Sensitive Hypertension

Sheon Mary et al.

Summary: The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in kidney and cardiovascular research. Variants of uromodulin are associated with chronic kidney diseases and hypertension. Urinary and circulating uromodulin levels reflect kidney and cardiovascular health and overall mortality. Genetically driven levels of uromodulin have been shown to have a causal and adverse effect on kidney function. Uromodulin is involved in salt reabsorption and plays a significant role in the pathophysiology of hypertension. This review provides an overview of the multifaceted physiology and pathophysiology of uromodulin, including recent advances in its genetics, cellular trafficking, and mechanistic and clinical studies.

HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Role of α1-blockers in the current management of hypertension

Hua Li et al.

Summary: There is increasing evidence supporting the safe use of alpha 1-blockers in the treatment of hypertension. These drugs are effective in controlling blood pressure in almost all hypertensive patients, with special indications including benign prostatic hyperplasia, resistant hypertension, and primary aldosteronism screen. However, careful consideration is required for the choice of long-acting alpha 1-blockers, potential orthostatic hypotension in the elderly, and fluid retention.

JOURNAL OF CLINICAL HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Effectiveness of salt substitute on cardiovascular outcomes: A systematic review and meta-analysis

Yi-Ching Tsai et al.

Summary: This study aimed to evaluate the effect of salt substitute on blood pressure and cardiovascular disease. The meta-analysis of 23 randomized controlled trials showed that salt substitute significantly reduced systolic and diastolic blood pressure, decreased 24-hour urinary sodium, increased 24-hour urinary potassium, and reduced all-cause mortality. These findings suggest that salt substitute plays an important role in improving blood pressure control and reducing mortality risk.

JOURNAL OF CLINICAL HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Blood pressure response to standing is a strong determinant of masked hypertension in young to middle-age individuals

Paolo Palatini et al.

Summary: This study found that blood pressure response to standing is an important determinant of masked hypertension in young individuals. People with a response higher than 6.5 mmHg and high urinary epinephrine levels are at higher risk of masked hypertension, suggesting a role of sympathoadrenergic activity in the pathogenesis of masked hypertension.

JOURNAL OF HYPERTENSION (2022)

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Article Peripheral Vascular Disease

Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women

Allison E. Gaffey et al.

Summary: Veterans, especially women, are three times more likely to experience sexual harassment and assault than civilians. A study found that military sexual trauma (MST) is independently associated with incident hypertension, and the association may be greater for women. This emphasizes the importance of addressing the mental health and cardiovascular health of veterans.

JOURNAL OF HYPERTENSION (2022)

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Review Peripheral Vascular Disease

Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of Hypertension

George Stergiou et al.

Summary: Antihypertensive drug therapy is effective for preventing disability and death globally, and complete 24-hour blood pressure control should be the primary goal. While bedtime administration of antihypertensive drugs has been proposed as potentially more effective, high-quality data from well-designed studies are needed to support this claim.

JOURNAL OF HYPERTENSION (2022)

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Review Cardiac & Cardiovascular Systems

Cardiac Phenotypes in Secondary Hypertension JACC State-of-the-Art Review

Andrzej Januszewicz et al.

Summary: Secondary hypertension carries a higher risk of cardiac morbidity and mortality. Studying cardiac phenotypes in secondary hypertension helps understand the underlying mechanisms affecting the heart. The higher prevalence of heart damage in these patients compared to those with primary hypertension can be attributed to specific clinical and biochemical phenotypes, providing an opportunity for early screening and monitoring of heart damage and personalized treatment.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Article Cardiac & Cardiovascular Systems

Cumulative Systolic Blood Pressure Load and Cardiovascular Risk in Patients With Diabetes

Nelson Wang et al.

Summary: The study found that cumulative systolic blood pressure load was associated with an increased risk of cardiovascular events and death in patients with type 2 diabetes, and provided better prediction compared to traditional blood pressure measures.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2022)

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Article Medicine, General & Internal

Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial

Isla S. Mackenzie et al.

Summary: The TIME study aimed to investigate whether evening dosing of antihypertensive medication improves cardiovascular outcomes compared with morning dosing. The results showed that there was no difference in major cardiovascular outcomes between evening dosing and morning dosing, and patients can choose a convenient time to take their medications.

LANCET (2022)

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Article Medicine, General & Internal

Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial

Pengfei Yang et al.

Summary: Intensive blood pressure control to lower than 120 mm Hg should be avoided in patients who have received endovascular thrombectomy for acute ischaemic stroke due to intracranial large-vessel occlusion, as it may compromise functional recovery. The more intensive treatment group showed a higher likelihood of poor functional outcome, early neurological deterioration, and major disability at 90 days compared to the less intensive treatment group.

LANCET (2022)

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Article Medicine, General & Internal

Long-term outcomes after catheter-based renal artery denervation for resistant hypertension: final follow-up of the randomised SYMPLICITY HTN-3 Trial

Deepak L. Bhatt et al.

Summary: The 36-month follow-up of the SYMPLICITY HTN-3 trial demonstrates the long-term safety and efficacy of renal artery denervation in patients with treatment-resistant hypertension. Patients who received renal artery denervation showed significant reductions in blood pressure and better blood pressure control compared to those who received sham control.

LANCET (2022)

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Article Medicine, General & Internal

Angiotensin receptor blockers and β blockers in Marfan syndrome: an individual patient data meta-analysis of randomised trials

Alex Pitcher et al.

Summary: In patients with Marfan syndrome, ARBs reduce the rate of increase in the aortic root Z score, including among those taking beta blockers. The effects of beta blockers are similar to those of ARBs. Combination therapy with ARBs and beta blockers provides a more significant reduction in the rate of aortic enlargement than either treatment alone.

LANCET (2022)

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Article Medicine, General & Internal

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction

S. D. Solomon et al.

Summary: The study shows that SGLT2 inhibitors are effective in reducing the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less. However, whether they are effective in patients with a higher left ventricular ejection fraction remains uncertain.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Editorial Material Medicine, General & Internal

A polypill improves secondary prevention of heart attack

H. Vaillant et al.

EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE (2022)

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Article Medicine, General & Internal

Prevalence of isolated diastolic hypertension and the risk of cardiovascular mortality among adults aged 40 years and older in northeast China: a prospective cohort study

Ling Yue et al.

Summary: Isolated diastolic hypertension is prevalent among young and middle-aged populations in northeast China, with lower awareness and treatment rates compared to non-isolated diastolic hypertension patients. Both isolated diastolic hypertension and non-isolated diastolic hypertension are significantly associated with an increased risk of cardiovascular disease mortality.

BMJ OPEN (2022)

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Review Cardiac & Cardiovascular Systems

Global Burden, Regional Differences, Trends, and Health Consequences of Medication Nonadherence for Hypertension During 2010 to 2020: A Meta-Analysis Involving 27 Million Patients

Eric K. P. Lee et al.

Summary: Nonadherence to antihypertensive medications is a global problem, especially in low-to middle-income and non-Western countries. Interventions are urgently needed, particularly in these regions.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Article Cardiac & Cardiovascular Systems

Prediction of Cardiovascular Events by Pulse Waveform Parameters: Analysis of CARTaGENE

Louis-Charles Desbiens et al.

Summary: This study analyzed participants from a population-based cohort and explored the association between waveform parameters and cardiovascular events. The results showed that certain waveform parameters are independently associated with adverse cardiovascular events, especially in patients with low cardiovascular risk. The augmentation index and reflection magnitude slightly improve risk prediction.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2022)

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Article Medicine, General & Internal

Association of Sodium-Glucose Cotransporter-2 Inhibitors With Incident Atrial Fibrillation in Older Adults With Type 2 Diabetes

Min Zhuo et al.

Summary: The use of SGLT-2 inhibitors is associated with a reduced risk of incident atrial fibrillation in older adults with type 2 diabetes.

JAMA NETWORK OPEN (2022)

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Article Public, Environmental & Occupational Health

The associations of job strain and leisure-time physical activity with the risk of hypertension: the population-based Midlife in the United States cohort study

Xinyue Liu et al.

Summary: This study found that job strain is positively associated with incident hypertension, while leisure-time physical activity is inversely associated with incident hypertension. Individuals with high job strain and low leisure-time physical activity have the highest risk for hypertension.

EPIDEMIOLOGY AND HEALTH (2022)

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Review Pharmacology & Pharmacy

Impact of intervention of community pharmacists on cardiovascular outcomes in Spain: A systematic review

Marjan Manouchehri et al.

Summary: The study suggests that community pharmacist counselling and personalized intervention could have a positive impact on the prevention and control of cardiovascular diseases in Spain, particularly in terms of medication reconciliation and the management of hypertension, dyslipidemia, obesity, and diabetes.

JOURNAL OF PHARMACY & PHARMACOGNOSY RESEARCH (2022)

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Article Cardiac & Cardiovascular Systems

Consumer-Led Screening for Atrial Fibrillation: Frontier Review of the AF-SCREEN International Collaboration

Axel Brandes et al.

Summary: The article discusses the technological advancements and availability of consumer-led atrial fibrillation (AF) screening and points out the complexities and uncertainties surrounding this field. It highlights the lack of evidence supporting significant stroke reduction through consumer-led AF screening and emphasizes the need for larger studies to evaluate the effectiveness and cost-effectiveness of this approach.

CIRCULATION (2022)

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Review Rheumatology

Prevention and risk assessment of cardiovascular events in a population of patients with psoriasis and psoriatic arthritis

Robert Olszewski et al.

Summary: Psoriasis is a chronic, inflammatory disease often associated with other diseases of similar pathogenesis. The common denominator for this group of diseases is the inflammatory process that leads to various health consequences, which can be prevented by modifying lifestyle and incorporating appropriate treatment.

REUMATOLOGIA (2022)

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Article Cardiac & Cardiovascular Systems

Durability of blood pressure reduction after ultrasound renal denervation: three-year follow-up of the treatment arm of the randomised RADIANCE-HTN SOLO trial

Florian Rader et al.

Summary: This study assessed the long-term durability of ultrasound RDN in lowering blood pressure. The results showed that over a period of 36 months, patients experienced reduced blood pressure and improved blood pressure control, without any new long-term safety concerns.

EUROINTERVENTION (2022)

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Article Medicine, General & Internal

Polypill Strategy in Secondary Cardiovascular Prevention

Jose M. Castellano et al.

Summary: The study showed that taking a polypill containing aspirin, ramipril, and atorvastatin within 6 months after myocardial infarction significantly reduced the risk of major adverse cardiovascular events compared to usual care.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Cardiac & Cardiovascular Systems

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS) Developed by the task force on cardio-oncology of the European Society of Cardiology (ESC)

Alexander R. Lyon et al.

EUROPEAN HEART JOURNAL (2022)

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Review Peripheral Vascular Disease

Angiotensin Receptor Blockers in the Management of Hypertension: A Real-World Perspective and Current Recommendations

Giovanna Gallo et al.

Summary: Hypertension is a common cardiovascular risk factor, and ACEi and ARBs are recommended as first-line drugs for its management. These drugs have similar antihypertensive effects, but ARBs have better tolerability and provide protection against cardiovascular and renal damage.

VASCULAR HEALTH AND RISK MANAGEMENT (2022)

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Article Medicine, General & Internal

Tirzepatide Once Weekly for the Treatment of Obesity

Ania M. Jastreboff et al.

Summary: In this 72-week trial in participants with obesity, once-weekly doses of 5 mg, 10 mg, or 15 mg of tirzepatide provided substantial and sustained reductions in body weight, and improvements in cardiometabolic measures were also observed.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Letter Cardiac & Cardiovascular Systems

Home blood pressure during COVID-19-related lockdown in patients with hypertension

Martino F. Pengo et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2022)

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Review Pediatrics

The importance of the epithelial sodium channel in determining salt sensitivity in people of African origin

Erika Jones et al.

Summary: Hypertension is highly prevalent in Black Africans, who are more salt sensitive and have increased variants in the ENaC, leading to worse blood pressure control. Increased ENaC activity contributes to sodium and water retention as well as vascular stiffness, making hypertension more difficult to control. The use of the diuretic amiloride may be beneficial for severe and resistant hypertension in Black Africans.

PEDIATRIC NEPHROLOGY (2021)

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Article Anesthesiology

Oscillometric versus invasive blood pressure measurement in patients with shock: a prospective observational study in the emergency department

Agnes S. Meidert et al.

Summary: The accuracy of oscillometric blood pressure measurement in hypotensive patients was investigated in a prospective observational study in the resuscitation area of the emergency department. The study found that oscillometric measurements tended to overestimate blood pressure compared to invasive measurements, leading to an inability to reliably detect hypotension in emergency patients.

JOURNAL OF CLINICAL MONITORING AND COMPUTING (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Management of patients with combined arterial hypertension and aortic valve stenosis: a consensus document from the Council on Hypertension and Council on Valvular Heart Disease of the European Society of Cardiology, the European Association of Cardiovascular Imaging (EACVI), and the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

Costantino Mancusi et al.

Summary: Aortic valve stenosis and arterial hypertension often coexist, leading to more adverse cardiovascular outcomes. Hypertension may underestimate the severity of AS and patients should be reassessed after blood pressure control. Management of hypertension in AS patients should be cautious, aiming to achieve target blood pressure values with appropriate medication.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2021)

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Article Cardiac & Cardiovascular Systems

Adherence to prescribed medications in patients with heart failure: insights from liquid chromatography-tandem mass spectrometry-based urine analysis

Joanne Simpson et al.

Summary: This study utilized urine testing to evaluate medication adherence in patients with heart failure, finding that one in five patients evaluated 4-6 weeks after hospitalization exhibited non-adherence issues, with 17.6% being partially or completely non-adherent.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2021)

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Article Substance Abuse

Physicians' very brief (30-sec) intervention for smoking cessation on 13 671 smokers in China: a pragmatic randomized controlled trial

Yee Tak Derek Cheung et al.

Summary: The study showed that a 30-second smoking cessation intervention by physicians was effective in increasing self-reported abstinence among male smokers in China, indicating its feasibility and potential for delivery by all healthcare professionals in most settings.

ADDICTION (2021)

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Review Cardiac & Cardiovascular Systems

The Task Force for the management of adult congenital heart disease of the European Society of Cardiology (ESC)

Helmut Baumgartner et al.

EUROPEAN HEART JOURNAL (2021)

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Review Cardiac & Cardiovascular Systems

Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine

Rajiv Agarwal et al.

Summary: This review covers the development of mineralocorticoid receptor antagonists (MRAs) over the last 80 years, discussing the differences in mechanisms and effects between nonsteroidal and steroidal MRAs. Nonsteroidal MRAs demonstrate important distinctions in distribution, binding mode, and gene expression compared to steroidal MRAs.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

Jean-Philippe Collet et al.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

Gerhard Hindricks et al.

EUROPEAN HEART JOURNAL (2021)

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Article Peripheral Vascular Disease

Meta-analysis of changes in the levels of catecholamines and blood pressure with continuous positive airway pressure therapy in obstructive sleep apnea

Mackenzie Green et al.

Summary: CPAP treatment can reduce catecholamine levels and blood pressure in patients with obstructive sleep apnea, suggesting that sympathetic activity plays a crucial role in hypertension associated with OSA-related stress.

JOURNAL OF CLINICAL HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Automated blood pressure measurement in atrial fibrillation: validation process modification and evaluation of a novel professional device which detects atrial fibrillation and adapts its blood pressure measurement algorithm

George S. Stergiou et al.

Summary: The study evaluated the accuracy of a novel professional oscillometric upper-arm cuff device in AF patients, which introduces a challenging solution for clinical practice. Validation of BP monitors in AF patients should not ignore their inherently high BP variability.

JOURNAL OF HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review

Paul J. Connelly et al.

Summary: Limited studies suggest that transgender men undergoing gender-affirming hormone therapy typically do not experience significant changes in blood pressure; while blood pressure in transgender women may show trends of increase or decrease. However, the current research is characterized by significant methodological limitations and insufficient quality.

JOURNAL OF HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Dietary Intervention to Improve Blood Pressure Control: Beyond Salt Restriction

Arrigo F. G. Cicero et al.

Summary: Lifestyle improvements play a crucial role in preventing cardiovascular diseases and controlling blood pressure, with low-salt diets being particularly effective in reducing blood pressure. Alongside low-salt diets, the DASH diet and low-salt Mediterranean diet are recommended for optimal blood pressure reduction, while lacto-ovo vegetarian diets and weight loss can also significantly improve blood pressure levels. Additionally, certain nutraceuticals such as beetroot, magnesium, and catechin-rich beverages have been shown to lower blood pressure.

HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION (2021)

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Article Pharmacology & Pharmacy

Impact of a Pharmacist First innovative workflow plan in patients with hypertension and/or diabetes

Randy So et al.

CANADIAN PHARMACISTS JOURNAL (2021)

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Review Clinical Neurology

Impact of CPAP on arterial stiffness in patients with obstructive sleep apnea: a meta-analysis of randomized trials

Sintya T. Chalegre et al.

Summary: This study aimed to evaluate the effect of CPAP on markers of arterial stiffness in OSA patients. Results showed that CPAP significantly reduced PWV but did not significantly affect Aix. Further randomized trials are recommended to confirm these findings.

SLEEP AND BREATHING (2021)

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Review Urology & Nephrology

The Promise of Tubule Biomarkers in Kidney Disease: A Review

Joachim H. Ix et al.

Summary: Serum creatinine has been the primary index for kidney disease detection and monitoring for over 70 years, but recent discoveries of kidney tubule biomarkers have provided additional information on the progression of chronic kidney disease. These biomarkers offer new opportunities for monitoring therapeutic responses in CKD patients.

AMERICAN JOURNAL OF KIDNEY DISEASES (2021)

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Article Peripheral Vascular Disease

Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension

Eirik Olsen et al.

Summary: The study found that in middle-aged and elderly patients with type 2 diabetes and hypertension, more frequent achievement of blood pressure <140/90mmHg helped reduce cardiovascular risk, while achieving blood pressure <130/80mmHg did not have an impact on cardiovascular risk.

BLOOD PRESSURE (2021)

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Review Medical Laboratory Technology

Lipoprotein(a) and Cardiovascular Disease

Pia R. Kamstrup

Summary: This review article presents evidence from large genetic epidemiologic studies supporting a causal role of high lipoprotein(a) concentrations in cardiovascular disease, and discusses measurements of lipoprotein(a) and potential treatment options. Further research is needed to confirm causality and evaluate the clinical benefits of lowering therapies.

CLINICAL CHEMISTRY (2021)

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Article Pharmacology & Pharmacy

Characterizing Effects of Antidiabetic Drugs on Heart Rate, Systolic and Diastolic Blood Pressure

John Maringwa et al.

Summary: This study revealed clinically relevant effects of antidiabetic drugs on heart rate and systolic blood pressure, with GLP1 receptor agonists showing the largest impact on these cardiovascular endpoints. Additional research is needed to further investigate the long-term impact of AD-related decreases in SBP combined with increases in HR on cardiovascular mortality.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)

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Article Cardiac & Cardiovascular Systems

Effect of blood pressure lowering drugs and antibiotics on abdominal aortic aneurysm growth: a systematic review and meta-analysis

Jonathan Golledge et al.

Summary: This meta-analysis indicates that neither blood pressure-lowering medications nor antibiotics can limit the growth or clinically relevant events in patients with abdominal aortic aneurysms.

HEART (2021)

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Article Peripheral Vascular Disease

Reproducibility of Office and Out-of-Office Blood Pressure Measurements in Children Implications for Clinical Practice and Research

George S. Stergiou et al.

Summary: This study demonstrates that in children and adolescents, 24-hour ABP and 7-day HBP have similar reproducibility, superior to OBP and daytime or asleep ABP. This has significant implications for diagnosing hypertension in children in clinical practice and designing clinical research trials in pediatric hypertension.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Routine assessment of cognitive function in older patients with hypertension seen by primary care physicians: why and how-a decision-making support from the working group on 'hypertension and the brain' of the European Society of Hypertension and from the European Geriatric Medicine Society

Angelo Scuteri et al.

Summary: The European Societies of Hypertension and Cardiology guidelines have recognized cognitive function decline as a hypertension-mediated organ damage, which can be the only hypertension-mediated organ damage in over 30% of hypertensive patients. It is crucial for the medical community to have a pragmatic approach to identify and treat these patients early. Moreover, there is a clear connection between exposure to high blood pressure and the development of cognitive decline, making it necessary to standardize clinical evaluation and treatment practices for hypertensive patients, especially in older populations.

JOURNAL OF HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Lifestyle, psychological, socioeconomic and environmental factors and their impact on hypertension during the coronavirus disease 2019 pandemic

Reinhold Kreutz et al.

Summary: The COVID-19 pandemic has had a significant impact on various aspects of daily life, including blood pressure control and cardiovascular risk. Lifestyle factors, dietary patterns, alcohol consumption, and other behaviors may influence blood pressure during the pandemic, necessitating preventive measures to improve blood pressure control.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Monotherapy vs combination treatments of different complexity: a meta-analysis of blood pressure lowering randomized outcome trials

Costas Thomopoulos et al.

Summary: Using drug combinations for hypertension treatment is recommended for most patients as they show better blood pressure-lowering effects compared to monotherapy. Randomized clinical trials indicate that combination treatments reduce fatal and nonfatal outcomes compared to simpler treatment regimens, however, the presence of treatment-related adverse events may affect the overall benefit of combination therapy.

JOURNAL OF HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Sodium--glucose co-transporter-2 inhibitors for patients with diabetic and nondiabetic chronic kidney disease: a new era has already begun

Pantelis Sarafidis et al.

Summary: SGLT-2 inhibitors have shown significant benefits in the treatment of CKD in diabetic patients, delaying disease progression and reducing risks, and are suitable for both diabetic and non-diabetic patients.

JOURNAL OF HYPERTENSION (2021)

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Article Urology & Nephrology

Stopping Renin-Angiotensin System Inhibitors in Patients with Advanced CKD and Risk of Adverse Outcomes: A Nationwide Study

Edouard L. Fu et al.

Summary: The study found that stopping RAS inhibitor therapy in patients with advanced CKD was associated with higher risks of mortality and major adverse cardiovascular events, but lower risk of initiating kidney replacement therapy (KRT).

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Genomics of hypertension: the road to precision medicine

Sandosh Padmanabhan et al.

Summary: The genetic architecture of blood pressure is complex, involving multiple genes and SNPs, but currently only explains a portion of its heritability. Studying blood pressure syndromes may help to better understand the biological mechanisms of the disease.

NATURE REVIEWS CARDIOLOGY (2021)

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Article Transplantation

Change in ankle-brachial index and mortality among individuals with chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort Study

Kirsten S. Dorans et al.

Summary: The study revealed a U-shaped association between changes in ABI and all-cause mortality in patients with chronic kidney disease. Both larger decreases and increases in average annual changes in ABI (>0.04/year) were associated with higher mortality risk, suggesting that monitoring changes in ABI over time may help in risk stratification for mortality among individuals with CKD.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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Article Transplantation

Renin-angiotensin system blocker discontinuation and adverse outcomes in chronic kidney disease

Carl P. Walther et al.

Summary: Discontinuation of ACEI/ARB therapy among patients with non-dialysis-dependent CKD was associated with a higher risk of death and incident ESKD, indicating a need for further investigations into the causes of therapy discontinuation and evidence-based decision-making.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2021)

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Article Medicine, General & Internal

Polypill with or without Aspirin in Persons without Cardiovascular Disease

S. Yusuf et al.

Summary: This study showed that combined treatment with a polypill plus aspirin reduced cardiovascular events among participants without cardiovascular disease but at intermediate cardiovascular risk. However, the polypill alone or aspirin alone did not significantly reduce cardiovascular events. Participants in the polypill group had a higher incidence of hypotension or dizziness compared to the placebo group.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Review Endocrinology & Metabolism

Predictors of successful weight loss outcomes amongst individuals with obesity undergoing lifestyle interventions: A systematic review

Sakshi Chopra et al.

Summary: This systematic review identified predictors of successful weight loss among overweight or obese individuals undergoing lifestyle interventions. It found that factors such as being male, older in age, having existing cardiometabolic comorbidities, limited fat intake, greater initial weight loss, and higher adherence to lifestyle advice were associated with greater weight loss success. Initial weight loss was determined to be the most important predictor of successful weight loss outcome.

OBESITY REVIEWS (2021)

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Editorial Material Pediatrics

The USPSTF call to inaction on blood pressure screening in children and adolescents

Bonita Falkner et al.

PEDIATRIC NEPHROLOGY (2021)

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Article Peripheral Vascular Disease

Isolated Diastolic Hypertension in the IDACO Study: An Age-Stratified Analysis Using 24-Hour Ambulatory Blood Pressure Measurements

John W. McEvoy et al.

Summary: Using ambulatory blood pressure monitor data, the study suggests that isolated diastolic hypertension defined by 2017 ACC/AHA criteria is not a risk factor for cardiovascular disease in adults aged 50 years or older but is a risk factor among younger adults. Age is an important consideration in the clinical management of adults with isolated diastolic hypertension.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Cardiovascular Prognosis in Drug-Resistant Hypertension Stratified by 24-Hour Ambulatory Blood Pressure: The JAMP Study

Kazuomi Kario et al.

Summary: Resistant hypertension is an important cardiovascular risk factor that significantly increases the risk of heart failure and overall cardiovascular events. Patients with true resistant hypertension had a higher risk of cardiovascular events and heart failure compared to those with well-controlled nonresistant hypertension or uncontrolled nonresistant hypertension. Proper diagnosis and treatment of resistant hypertension are crucial in preventing cardiovascular disease events.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk

Stephane Laurent et al.

Summary: The SPARTE study showed that a PWV-driven treatment for hypertension can further reduce office and ambulatory blood pressure, prevent vascular aging, and was more effective compared to strict guideline-based therapy.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Sympathetic Neural Mechanisms Underlying Attended and Unattended Blood Pressure Measurement

Guido Grassi et al.

Summary: The study investigated the differences in blood pressure values when measured with or without a doctor present. The results showed that there were significant increases in blood pressure and sympathetic nerve traffic when BP was measured in the presence of a doctor, while there were modest decreases in these values during unattended BP measurement. This suggests that the presence of a doctor during BP measurement may affect cardiovascular and neural responses.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

White-Coat Hypertension: Pathophysiological and Clinical Aspects: Excellence Award for Hypertension Research 2020

Giuseppe Mancia et al.

Summary: White-coat hypertension, a condition where office blood pressure is elevated while out-of-office blood pressure is normal, has been controversial in modern cardiovascular medicine. Recent studies have shown that WCH is associated with an increased cardiovascular risk, changing previous conclusions.

HYPERTENSION (2021)

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Article Health Care Sciences & Services

Gender differences in quality of life, physical activity, and risk of hypertension among sedentary occupation workers

Hanan E. Badr et al.

Summary: This study aimed to explore gender differences among sedentary occupation workers with regard to their quality of life, physical activity, and risk for high blood pressure. Factors such as socio-demographics, physical activity, and health status were found to be correlated to quality of life. Gender differences existed in quality of life, physical activity, and risk of hypertension.

QUALITY OF LIFE RESEARCH (2021)

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Article Medicine, General & Internal

Home and Online Management and Evaluation of Blood Pressure (HOME BP) using a digital intervention in poorly controlled hypertension: randomised controlled trial

Richard J. McManus et al.

Summary: The HOME BP trial tested a digital intervention for hypertension management in primary care, showing that self-monitoring of blood pressure combined with digital intervention led to better control of systolic blood pressure with low incremental costs.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Association of SGLT2 inhibitors with risk of atrial fibrillation and stroke in patients with and without type 2 diabetes

Ru-Jie Zheng et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

On-Treatment Blood Pressure and Cardiovascular Outcomes in Adults With Hypertension and Left Ventricular Hypertrophy

Hyeok-Hee Lee et al.

Summary: This study found that maintaining blood pressure at SBP <130 mm Hg and DBP <80 mm Hg was associated with the lowest risk for cardiovascular events in adults with hypertension and LVH. Further randomized trials are needed to establish optimal blood pressure-lowering strategies for these patients.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Blood Pressure Effects of Sodium Reduction Dose-Response Meta-Analysis of Experimental Studies

Tommaso Filippini et al.

Summary: The study demonstrates an approximately linear relationship between dietary sodium intake and blood pressure, indicating that reducing sodium intake can lead to a decrease in blood pressure, with a more pronounced effect in individuals with hypertension.

CIRCULATION (2021)

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Letter Cardiac & Cardiovascular Systems

Sex Differences in Blood Pressure Associations With Cardiovascular Outcomes

Hongwei Ji et al.

CIRCULATION (2021)

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Article Cardiac & Cardiovascular Systems

A cohort study and meta-analysis of isolated diastolic hypertension: searching for a threshold to guide treatment

Alan P. Jacobsen et al.

Summary: IDH defined by the 2017 ACC/AHA guidelines does not show consistent associations with subclinical CVD or CVD events in the Multi-Ethnic Study of Atherosclerosis (MESA) and in a meta-analysis of seven other cohort studies. Emphasis on healthy lifestyle rather than drug therapy may be sufficient for middle-aged or older adults meeting the IDH criteria, but follow-up for incident systolic hypertension is recommended.

EUROPEAN HEART JOURNAL (2021)

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Article Peripheral Vascular Disease

Aortic Pulse Wave Velocity Predicts Cardiovascular Events and Mortality in Patients Undergoing Coronary Angiography A Comparison of Invasive Measurements and Noninvasive Estimates

Bernhard Hametner et al.

Summary: Aortic pulse wave velocity (PWV) is directly related to arterial stiffness. This prospective study evaluated the prognostic value of PWV in high-risk patients with suspected coronary artery disease and compared 3 different methods for assessing PWV. The study found that all 3 methods for determining PWV were able to predict cardiovascular events and mortality in patients with suspected coronary artery disease.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Adding Home and/or Ambulatory Blood Pressure to Office Blood Pressure for Cardiovascular Risk Prediction

Giuseppe Mancia et al.

Summary: The addition of home and 24-hour blood pressure to office blood pressure significantly improves the prediction of cardiovascular and all-cause mortality, especially with the addition of home blood pressure. However, the quantitative improvement is modest, raising questions about the extended use of these methods in clinical practice.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Adherence to Single-Pill Versus Free-Equivalent Combination Therapy in Hypertension A Systematic Review and Meta-Analysis

Gianfranco Parati et al.

Summary: Single-pill combination (SPC) therapy was found to lead to improved adherence and persistence compared to free-equivalent combination (FEC) therapy in patients with hypertension, resulting in better blood pressure control. Studies showed that patients receiving SPCs had significantly enhanced adherence and lower likelihood of discontinuation compared to those receiving FECs. Moreover, SPC therapy led to significant reductions in both systolic and diastolic blood pressure at week 12, highlighting its potential benefits for patients with hypertension.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Urate, Blood Pressure, and Cardiovascular Disease Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials

Dipender Gill et al.

Summary: Mendelian randomization analysis suggests that genetically predicted serum urate levels are associated with increased risk of coronary heart disease, peripheral artery disease, and stroke. Elevated blood pressure may mediate a significant portion of the effect of urate on cardiovascular disease risk. High-quality trials are needed to determine the specific clinical contexts where lowering urate levels may benefit cardiovascular health.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Furosemide for Accelerated Recovery of Blood Pressure Postpartum in Women with a Hypertensive Disorder of Pregnancy A Randomized Controlled Trial

Joana Lopes Perdigao et al.

Summary: This study suggests that a short course of postpartum furosemide significantly improves blood pressure control in women with hypertensive disorders of pregnancy, particularly among those without severe disease. The use of furosemide reduced the risk of persistent hypertension at 7 days postpartum and shortened the days to resolution of hypertension, without significant differences in readmissions or need for additional antihypertensive medication between groups.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Starting Antihypertensive Drug Treatment With Combination Therapy Controversies in Hypertension - Pro Side of the Argument

Alexandre Persu et al.

HYPERTENSION (2021)

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Article Medicine, General & Internal

Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease

Rajiv Agarwal et al.

Summary: In patients with CKD and poorly controlled hypertension, chlorthalidone therapy improved blood pressure control at 12 weeks compared to placebo.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Peripheral Vascular Disease

A double-blind, placebo-controlled trial on the antihypertensive treatment effect of a quadruple single-pill combination

Lei-Xiao Hu et al.

Summary: The study demonstrates that the quadruple combination of antihypertensive drugs reduced blood pressure and led to changes in plasma neurotransmitters.

JOURNAL OF CLINICAL HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Cardiovascular outcomes in patients at high cardiovascular risk with previous myocardial infarction or stroke

Michael Boehm et al.

Summary: The study showed that patients with a history of myocardial infarction and stroke are at increased risk of experiencing the same event in the future, independent of their achieved systolic blood pressure levels.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement

George S. Stergiou et al.

Summary: The collaborators come from different countries and regions, representing experts in the field of hypertension research, working together to make contributions.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Isolated systolic and diastolic hypertension by the 2017 American College of Cardiology/American Heart Association guidelines and risk of cardiovascular disease: a large prospective cohort study

Fu-Rong Li et al.

Summary: The 2017 American College of Cardiology/American Heart Association guidelines lowered the hypertension threshold to 130/80 mmHg, with isolated systolic hypertension (ISH) and isolated diastolic hypertension (IDH) significantly associated with cardiovascular disease risk.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Therapeutic inertia in the management of hypertension in primary care

Dalia H. Ali et al.

Summary: Therapeutic inertia is common in primary care patients with uncontrolled hypertension, and is associated with older age, closer to target SBP, and concurrent diabetes. General practice physicians often do not intensify treatment due to various reasons, such as considering office BP measurements as nonrepresentative or waiting for next BP readings.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Prognostic role of the ascending aorta dilatation in patients with arterial hypertension

Dario Leone et al.

Summary: Ascending aorta diameter and dilatation are both associated with an increased risk of cardiovascular events, and assessing ASC can improve risk stratification in hypertensive patients.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Complementary value of ECG and echocardiographic left ventricular hypertrophy for prediction of adverse outcomes in the general population

Zhi Du et al.

Summary: The study demonstrated that ECG left ventricular hypertrophy (ECG-LVH) has prognostic value independent of echocardiography LVH (Echo-LVH), increasing the risk of incident stroke or coronary heart disease and mortality. ECG-LVH remained an independent risk factor for adverse outcomes and improved the prediction model within 4 years. These findings suggest the clinical relevance of considering ECG-LVH, especially in individuals with Echo-LVH, for risk stratification.

JOURNAL OF HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Renin-angiotensin-system inhibitors and all-cause mortality in patients with COVID-19: a systematic review and meta-analysis of observational studies

Chirag Bavishi et al.

Summary: After analyzing 34 studies on the association between ACEI/ARB treatment and clinical outcomes in COVID-19 patients, it was found that there was no significant association between ACEI/ARB treatment and mortality/severe disease.

JOURNAL OF HYPERTENSION (2021)

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Article Clinical Neurology

Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial

Mikael Mazighi et al.

Summary: This study aimed to evaluate the effect of different systolic blood pressure targets on rates of intraparenchymal hemorrhage in acute ischemic stroke patients after endovascular therapy. The results showed that an intensive systolic blood pressure target did not reduce intraparenchymal hemorrhage rates compared to a standard target. Further research is needed to understand the relationship between blood pressure and outcomes after reperfusion.

LANCET NEUROLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Immediate physiological effects of acute electronic cigarette use in humans: A systematic review and meta-analysis

Florent Larue et al.

Summary: This study analyzed clinical trial research findings and found that acute nicotine e-cig use is associated with increased cardiovascular physiological parameters such as heart rate and blood pressure, while exhaled nitric oxide decreases, with no significant impact on lung function tests.

RESPIRATORY MEDICINE (2021)

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Review Environmental Sciences

Is Mindfulness-Based Stress Reduction Effective for People with Hypertension? A Systematic Review and Meta-Analysis of 30 Years of Evidence

Ciro Conversano et al.

Summary: This study conducted a systematic review and meta-analysis of the effects of mindfulness-based stress reduction (MBSR) programs on hypertension, showing that MBSR has a significant impact on reducing diastolic blood pressure in hypertensive patients. The results suggest that MBSR may be a promising intervention for hypertension, especially in reducing diastolic blood pressure, but more well-conducted trials are needed for further validation.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Article Cardiac & Cardiovascular Systems

Low-fat hypocaloric diet reduces neprilysin in overweight and obese human subjects

Christine Henke et al.

Summary: This study identified weight loss through a low-fat diet as the first physiological intervention in humans to reduce NEP levels in plasma and adipose tissue, contributing to improved cardiac function in patients with heart failure.

ESC HEART FAILURE (2021)

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Review Urology & Nephrology

Assessment of kidney function: clinical indications for measured GFR

Natalie Ebert et al.

Summary: The article discusses the limitations of estimating glomerular filtration rate (GFR) using serum creatinine and proposes possible solutions such as using cystatin C or an exogenous marker for direct measurement. Various clinical scenarios where creatinine-based GFR estimation may be invalid are highlighted, emphasizing the importance of personalized medicine and the need for standardized GFR procedures.

CLINICAL KIDNEY JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

Fernando Riveros-Mckay et al.

Summary: The study developed a novel CAD polygenic risk score using the UK Biobank resource and combined it with established risk tools to form an integrated risk tool (IRT) with superior predictive accuracy. The IRT outperformed current risk stratification tools and is estimated to potentially avoid up to 12,000 deaths in the United States over a 5-year period, suggesting a greater opportunity for early interventions with the inclusion of polygenic risk in CAD risk tools.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2021)

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Article Medicine, General & Internal

Association of Long-term Use of Antihypertensive Medications With Late Outcomes Among Patients With Aortic Dissection

Shao-Wei Chen et al.

Summary: This study compared late outcomes after long-term use of beta-blockers, ACEIs/ARBs, or other antihypertensive medications among patients treated for aortic dissection. The results showed that the use of beta-blockers, ACEIs/ARBs, or ARBs was associated with benefits in the long-term treatment of aortic dissection.

JAMA NETWORK OPEN (2021)

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Article Medicine, General & Internal

Stratification of the risk of developing severe or lethal Covid-19 using a new score from a large Italian population: a population-based cohort study

Giovanni Corrao et al.

Summary: The study developed a COVID-19 Vulnerability Score model based on healthcare utilization databases in Italy to predict severe/fatal clinical manifestations of SARS-CoV-2 infection. Results showed a high predictive performance of the score, accurately identifying high-risk individuals and providing more precise intervention recommendations for health decision-makers.

BMJ OPEN (2021)

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Review Cardiac & Cardiovascular Systems

Adverse Pregnancy Outcomes and Cardiovascular Disease Risk: Unique Opportunities for Cardiovascular Disease Prevention in Women: A Scientific Statement From the American Heart Association

Nisha I. Parikh et al.

Summary: This statement summarizes the impact of adverse pregnancy outcomes on women's risk of cardiovascular disease and highlights the importance of recognizing this impact. Lifestyle interventions such as adopting a heart-healthy diet and increasing physical activity can help reduce CVD risk. Further research on non-White women is needed to address health disparities and inform recommendations for primary CVD prevention.

CIRCULATION (2021)

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Article Cardiac & Cardiovascular Systems

Device Therapy of Hypertension

Felix Mahfoud et al.

Summary: Efforts to improve blood pressure control have shifted towards interventional therapies targeting the sympathetic nervous system, with renal denervation being the most mature technology. Other emerging technologies like baroreflex activation therapy require more human data support. Central nervous system control of circulation remains poorly understood yet vital component, with deep brain stimulation of key cardiovascular control territories showing promise for blood pressure control. Technology targeting hemodynamics of circulation may also be worth exploring for patients with less relevant sympathetic drive to hypertension perpetuation.

CIRCULATION RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

Hypertension, a Moving Target in COVID-19 Current Views and Perspectives

Carmine Savoia et al.

Summary: COVID-19, caused by SARS-CoV-2, poses a high mortality rate and is currently a major global health concern. Male patients and older individuals, as well as those with chronic comorbidities, are at a higher risk of severe clinical manifestations. Experimental studies suggest that hypertension, particularly the activation of the renin-angiotensin system, may play a role in COVID-19 severity.

CIRCULATION RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

The Gut Microbiome in Hypertension Recent Advances and Future Perspectives

Ellen G. Avery et al.

Summary: The pathogenesis of hypertension involves multiple factors including genetic, environmental, hormonal, hemodynamic, and inflammatory forces. There is increasing evidence that the gut microbiome plays a significant role in hypertension. Lifestyle factors such as dietary fiber consumption and fasting can impact hypertension through modulation of the microbiome.

CIRCULATION RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

Hypertension and Prohypertensive Antineoplastic Therapies in Cancer Patients

Daan C. H. van Dorst et al.

Summary: The development of novel antineoplastic therapies has improved cancer prognosis and increased the number of survivors, but these survivors may face increased cardiovascular risks associated with anticancer treatments, particularly systemic hypertension. Cancer and hypertension share common risk factors and pathophysiological mechanisms, highlighting the need for further research on optimal management of hypertension during anticancer therapy.

CIRCULATION RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

Oxidative Stress and Hypertension

Kathy K. Griendling et al.

Summary: The link between oxidative stress and hypertension has been established in animal models, but remains elusive in humans. Research has expanded our understanding of reactive oxygen species and their impact on signaling pathways, with potential for developing novel antihypertensive therapies.

CIRCULATION RESEARCH (2021)

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Article Cardiac & Cardiovascular Systems

Pathophysiology of Hypertension The Mosaic Theory and Beyond

David G. Harrison et al.

Summary: Dr. Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s, advocating that hypertension is the result of many interacting factors. Over the years, new concepts have arisen that allow further refinements of the theory, emphasizing the interdependence of various nodes.

CIRCULATION RESEARCH (2021)

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Review Medicine, General & Internal

Orthostatic hypotension in older people: considerations, diagnosis and management

Melanie Dani et al.

Summary: Orthostatic hypotension is common in older people and associated with risks of falls, fractures, dementia, and death. Prompt recognition and treatment are essential, and adherence to simple management strategies can lead to significant improvements.

CLINICAL MEDICINE (2021)

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Review Cardiac & Cardiovascular Systems

Is Isolated Diastolic Hypertension an Important Phenotype?

Cesar A. Romero et al.

Summary: Isolated diastolic hypertension (IDH) is a common phenotype of hypertension, with recent guidelines increasing its prevalence and potentially decreasing associated cardiovascular risk. There is controversy over long-term cardiovascular risk and pharmacological intervention in IDH, suggesting a need to incorporate IDH into a broader category for further research.

CURRENT CARDIOLOGY REPORTS (2021)

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Review Peripheral Vascular Disease

Update on Treatment of Hypertension After Renal Transplantation

Christos Chatzikyrkou et al.

Summary: Recent studies have shown the sodium retaining effects of CNIs and the antihypertensive effects of chlorthalidone, while local activation of the RAAS plays a crucial role in the pathogenesis of posttransplant hypertension.

CURRENT HYPERTENSION REPORTS (2021)

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Article Endocrinology & Metabolism

Diagnosis and treatment of primary aldosteronism

Martin Reincke et al.

Lancet Diabetes & Endocrinology (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Elevated lipoprotein(a) and the risk of stroke in children, young adults, and the elderly

Sotirios Tsimikas

Summary: This editorial discusses a study that shows the association between LPA and large artery atherosclerosis stroke aetiology and recurrence in patients under the age of 60.

EUROPEAN HEART JOURNAL (2021)

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Article Peripheral Vascular Disease

Effect of Intensive Blood Pressure Control on Aortic Stiffness in the SPRINT-HEART

Bharathi Upadhya et al.

Summary: The study revealed that intensive blood pressure treatment significantly attenuated increases in carotid-femoral pulse wave velocity and aortic elastance index, suggesting a potential mechanism contributing to the observed benefits of intensive treatment in the SPRINT trial.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Adherence to Antihypertensive Medication and Incident Cardiovascular Events in Young Adults With Hypertension

Hokyou Lee et al.

Summary: Treatment and control rates for high blood pressure are unsatisfactory among young adults, with poor adherence to pharmacological treatment associated with higher risk for future cardiovascular events.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Predictive Importance of Blood Pressure Characteristics With Increasing Age in Healthy Men and Women The MORGAM Project

Julie K. K. Vishram-Nielsen et al.

Summary: The study found a positive association between age and systolic blood pressure, with a more pronounced effect in individuals over 50 years old. Systolic blood pressure and mean blood pressure were significantly associated with the cardiovascular endpoint, regardless of age group. Diastolic blood pressure showed independent predictive value in the younger age group.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Obstructive Sleep Apnea-Induced Neurogenic Nocturnal Hypertension A Potential Role of Renal Denervation?

Kazuomi Kario et al.

Summary: There is a bidirectional, causal relationship between obstructive sleep apnea (OSA) and hypertension, with hypoxia/hypercapnia-related sympathetic activation being the key mechanism. While continuous positive airway pressure is the gold standard therapy for OSA, its effects on blood pressure are modest. Antihypertensive agents targeting sympathetic pathways or the renin-angiotensin-aldosterone system may have potential in patients with comorbid hypertension and OSA.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Effect of KBP-5074 on Blood Pressure in Advanced Chronic Kidney Disease: Results of the BLOCK-CKD Study

George Bakris et al.

Summary: In patients with resistant or poorly controlled hypertension and advanced chronic kidney disease, the nonsteroidal mineralocorticoid receptor antagonist KBP-5074 effectively lowers blood pressure with some risk of hyperkalemia.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Short- and Long-Term Reproducibility of Nighttime Blood Pressure Phenotypes and Nocturnal Blood Pressure Reduction

Giuseppe Mancia et al.

Summary: This study reveals poor reproducibility of nighttime blood pressure phenotypes, with frequent shifts from dipping to nondipping phenotypes, especially among reverse and extreme dippers during treatment of hypertensives. Nighttime blood pressure phenotypes are largely inconsistent and only a minimal fraction of patients have persistent phenotypes over the study period.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Cardiovascular Protection With Sodium-Glucose Cotransporter-2 Inhibitors and Mineralocorticoid Receptor Antagonists in Chronic Kidney Disease A Milestone Achieved

Pantelis Sarafidis et al.

Summary: CKD and cardiovascular disease are closely linked, sharing risk factors and pathogenetic mechanisms. While ACE inhibitors and ARBs can delay CKD progression, their impact on cardiovascular events and mortality is limited. In contrast, SGLT-2 inhibitors and MRAs not only provide effective renal protection, but also offer important cardioprotection in this population.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Do β-Blockers Cause Depression? Systematic Review and Meta-Analysis of Psychiatric Adverse Events During β-Blocker Therapy

Thomas G. Riemer et al.

Summary: Analysis of large-scale data from double-blind, randomized controlled trials did not find an association between beta-blocker therapy and depression. Similarly, beta-blockers showed no effect on other psychiatric adverse events, except for a possible link with sleep-related disorders. Therefore, concerns about the impact of beta-blockers on mental health should not affect their clinical use.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Comprehensive Comparative Effectiveness and Safety of First-Line β-Blocker Monotherapy in Hypertensive Patients A Large-Scale Multicenter Observational Study

Seng Chan You et al.

Summary: The study found no significant differences in the effectiveness and safety when comparing the third-generation beta-blockers with atenolol as first-line treatment for hypertension, but patients on third-generation beta-blockers had a higher risk of stroke compared to those on ACE inhibitors and thiazide diuretics.

HYPERTENSION (2021)

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Review Immunology

Patients with systemic lupus erythematosus face a high risk of cardiovascular disease: A systematic review and Meta-analysis

Xiaohong Lu et al.

Summary: The systematic review and meta-analysis found that patients with systemic lupus erythematosus (SLE) have a higher risk of developing cardiovascular disease (CVD) compared to the general or healthy population, and the risk of CVD in lupus nephritis (LN) patients is significantly higher than in SLE patients.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

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Review Medicine, General & Internal

Screening for Hypertension in Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement

Alex H. Krist et al.

Summary: Hypertension is a prevalent condition with serious health risks. It is recommended to screen adults for hypertension using office blood pressure measurement and confirm the diagnosis with blood pressure measurements outside of clinical settings before starting treatment.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Review Peripheral Vascular Disease

Role of hypertension in kidney transplant recipients

Charalampos Loutradis et al.

Summary: Cardiovascular events are a leading cause of mortality in kidney transplant recipients, with high prevalence of hypertension continuing even after transplantation. Understanding the complex pathophysiology and optimal management of hypertension in this population remains a challenge due to limited research and unclear guidelines.

JOURNAL OF HUMAN HYPERTENSION (2021)

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Review Urology & Nephrology

Basic principles and new advances in kidney imaging

Anna Caroli et al.

Summary: Advancements in clinical renal imaging have allowed for detailed assessments of kidney structure and function, playing an increasingly important role in the evaluation and management of renal diseases. Various imaging modalities provide complementary information to aid in diagnosis, treatment, and monitoring of kidney conditions, highlighting the importance of choosing appropriate techniques based on clinical questions and underlying pathologies.

KIDNEY INTERNATIONAL (2021)

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Article Medicine, General & Internal

Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial

Michel Azizi et al.

Summary: Renal denervation through ultrasound treatment shows promising results in reducing blood pressure for patients with resistant hypertension, with greater effectiveness compared to a sham procedure within 2 months and similar safety outcomes. This may provide an alternative approach for patients with resistant hypertension to avoid adding more antihypertensive medications.

LANCET (2021)

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Editorial Material Medicine, General & Internal

Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure. An individual participant-level data meta-analysis

Denis Pouchain

EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE (2021)

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Article Oncology

Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis

Emma Copland et al.

Summary: This study found no consistent evidence linking antihypertensive medication use to cancer risk, providing reassurance to clinical practice. However, evidence for some comparisons was insufficient to entirely rule out excess risk, particularly for calcium channel blockers.

LANCET ONCOLOGY (2021)

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Article Medicine, General & Internal

Nonadherence to antihypertensive medications amongst patients with uncontrolled hypertension A retrospective study

Spoorthy Kulkarni et al.

Summary: This study highlights that medication nonadherence is a modifiable risk factor for patients with hypertension. The research found that sex and number of antihypertensive medications prescribed significantly impact the rate of nonadherence.

MEDICINE (2021)

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Article Cardiac & Cardiovascular Systems

Prediction of Masked Hypertension and Masked Uncontrolled Hypertension Using Machine Learning

Ming-Hui Hung et al.

Summary: This study developed machine learning-based prediction models to predict masked hypertension and masked uncontrolled hypertension using clinical characteristics. The models showed high sensitivity and negative predictive value, with the random forest model performing the best in both internal and external validation.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

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Review Cardiac & Cardiovascular Systems

Interplay between inflammation and thrombosis in cardiovascular pathology

Konstantin Stark et al.

Summary: Thrombosis is a major health challenge globally, with inflammation playing a crucial role in driving thrombotic diseases. Anti-inflammatory strategies show promise in targeting cardiovascular pathologies and addressing therapeutic gaps.

NATURE REVIEWS CARDIOLOGY (2021)

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Article Multidisciplinary Sciences

Antihypertensive treatment in a general uncontrolled hypertensive population in Belgium and Luxembourg in primary care: Therapeutic inertia and treatment simplification. The SIMPLIFY study

Tine De Backer et al.

Summary: The SIMPLIFY study identified therapeutic inertia in hypertension management, with key findings including patients with an average age of 64 years, average hypertension treatment duration of 8 years, nearly half of patients on monotherapy, over 80% of patients having their treatment modified during the study, and a preference for switching to single pill combination therapy. The study suggests that key drivers of therapeutic inertia are patient age, mild grade hypertension, isolated systolic hypertension, longer duration of antihypertensive treatment, and better therapeutic adherence.

PLOS ONE (2021)

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Article Multidisciplinary Sciences

Association of sex differences in dementia risk factors with sex differences in memory decline in a population-based cohort spanning 20-76 years

Kaarin J. Anstey et al.

Summary: The study found that memory decline in men in midlife and old age was associated with physical, cognitive, and social activities, while financial hardship was associated with memory decline. In women, dementia risk factors in midlife were associated with memory decline, and memory change in older women was associated with depression, cognitive and physical activity. Incident midlife hypertension was linked to greater memory decline in women, while incident late-life stroke was linked to greater memory decline in men. Women have fewer modifiable risk factors compared to men, and stroke and hypertension explained sex differences in memory decline for men and women respectively.

SCIENTIFIC REPORTS (2021)

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Article Genetics & Heredity

Hypertension in African Populations: Review and Computational Insights

Sihle E. Mabhida et al.

Summary: Hypertension is a global health problem affecting 1.3 billion individuals, with only 31% achieving control. Genetic variability in drug response and limited knowledge of pathophysiological mechanisms contribute to this issue. In Africa, there is a lack of pharmacogenomic data on treatment of resistant hypertension, prompting intensive investigation on identifying genetic signals to predict drug response in the population.

GENES (2021)

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Article Cardiac & Cardiovascular Systems

Estimated Prevalence of Masked Asleep Hypertension in US Adults

Siling Li et al.

Summary: This study found a high prevalence of masked asleep hypertension among US adults, highlighting the need for further research on the cardiovascular risk reduction benefits of treating asleep hypertension.

JAMA CARDIOLOGY (2021)

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Review Computer Science, Information Systems

A survey on deep learning and its applications

Shi Dong et al.

Summary: This paper primarily focuses on the development, classic models, latest applications, problems, and future research directions of deep learning in various fields such as speech processing, computer vision, natural language processing, and medical applications.

COMPUTER SCIENCE REVIEW (2021)

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Article Medicine, Research & Experimental

Adherence to Lipid-Lowering Treatment by Single-Pill Combination of Statin and Ezetimibe

Federico Rea et al.

Summary: Patients who were prescribed a single-pill combination of statin/ezetimibe were more likely to exhibit good adherence and less likely to have poor adherence to treatment compared to those prescribed a two-pill combination. This was associated with a decreased risk of cardiovascular events in patients with high adherence.

ADVANCES IN THERAPY (2021)

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Article Peripheral Vascular Disease

Adherence to Treatment by Initial Antihypertensive Mono and Combination Therapies

Federico Rea et al.

Summary: The study found that in a real-life setting in the Lombardy Region of Italy, patients who were initially prescribed a 2-drug single-pill combination were more likely to adhere well to antihypertensive treatment compared to those starting with a single drug.

AMERICAN JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Hypertension healthcare professional beliefs and behaviour regarding patient medication adherence: a survey conducted among European Society of Hypertension Centres of Excellence

Michel Burnier et al.

Summary: There is limited knowledge on the beliefs, perceptions, and practices of healthcare professionals managing hypertension in addressing non-adherence to therapy, particularly in ESH Excellence Centres. Most participants are physicians and nurses, with the majority of physicians having over 10 years of professional experience. Methods to discuss medications, assess adherence, and improve adherence include simplification of therapy, more frequent visits, and home blood pressure monitoring.

BLOOD PRESSURE (2021)

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Article Public, Environmental & Occupational Health

The different risk factors for isolated diastolic hypertension and isolated systolic hypertension: a national survey

Kun Xie et al.

Summary: The study revealed that patients with isolated diastolic hypertension (IDH) were younger, and the prevalence decreased with aging. Body mass index (BMI) and smoking were significantly associated with IDH but not with isolated systolic hypertension (ISH).

BMC PUBLIC HEALTH (2021)

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Article Cardiac & Cardiovascular Systems

GLP-1 receptor agonists and cardiorenal outcomes in type 2 diabetes: an updated meta-analysis of eight CVOTs

Dario Giugliano et al.

Summary: Glucagon-like peptide-1 receptor agonists have significant benefits on cardiovascular and renal outcomes in patients with type 2 diabetes, including reducing major cardiovascular events, hospitalization for heart failure, all-cause mortality, and the incidence of macroalbuminuria.

CARDIOVASCULAR DIABETOLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Artificial intelligence in echocardiography: detection, functional evaluation, and disease diagnosis

Jia Zhou et al.

Summary: Ultrasound is crucial for clinical diagnosis of cardiovascular diseases, with the speed of image movements driven by the beating heart being faster than other organs. Artificial intelligence is becoming an alternative for accurate diagnosis and treatment using echocardiography. Sonographers face challenges in accurately diagnosing due to the fast movement of heart images.

CARDIOVASCULAR ULTRASOUND (2021)

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Review Medicine, Research & Experimental

Cardiovascular toxicity of angiogenesis inhibitors and immune checkpoint inhibitors: synergistic anti-tumour effects at the cost of increased cardiovascular risk?

Daan C. H. van Dorst et al.

Summary: In the past two decades, novel anti-cancer therapies such as VEGFIs and ICIs have significantly improved treatment outcomes for a wide range of malignancies, but they are also associated with specific cardiovascular toxicities. Combining these two therapies may become an important direction for future treatment strategies, but it also poses an increased risk of cardiovascular toxicity, requiring close monitoring and evaluation by specialized teams.

CLINICAL SCIENCE (2021)

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Review Pharmacology & Pharmacy

Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies

Jose M. Valdivielso et al.

Summary: Despite the increasing global mortality rate associated with chronic kidney disease, recent advancements in novel kidney protective therapies have shown efficacy in clinical trials, providing hope for improved treatment outcomes.

DRUGS (2021)

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Article Cardiac & Cardiovascular Systems

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice Developed by the Task Force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC)

Frank L. J. Visseren et al.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Sacubitril-valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction

Alice M. Jackson et al.

Summary: The study showed that sacubitril-valsartan may be effective in treating apparent resistant hypertension in patients with HFpEF, even in those who continue to have elevated blood pressure despite treatment with at least four antihypertensive drug classes, including an MRA.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe

Steven Hageman et al.

Summary: The study aimed to develop, validate, and demonstrate an updated prediction model (SCORE2) to estimate 10-year cardiovascular disease risk in individuals without previous history of CVD or diabetes in Europe. The new algorithm, SCORE2, enhances the identification of individuals at higher risk of developing CVD across Europe by predicting first-onset CVD risk in European populations.

EUROPEAN HEART JOURNAL (2021)

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Editorial Material Cardiac & Cardiovascular Systems

Salt reduction to prevent hypertension: the reasons of the controversy

Feng J. He et al.

Summary: There is a causal relationship between dietary salt intake and blood pressure, reducing salt intake can benefit cardiovascular health. The relationship between salt intake levels and cardiovascular risk is controversial, with previous studies having methodological issues. Population-wide reduction in salt intake can improve public health and decrease healthcare costs.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions

Tamar de Vries et al.

Summary: The study developed and validated the SCORE2-OP risk model for estimating 5- and 10-year cardiovascular disease (CVD) risk in individuals aged over 70 years in four geographical regions. The models took into account various risk factors, were recalibrated to each region, and showed significant variation in CVD event risk across the four risk regions for different risk factor profiles.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

Theresa A. McDonagh et al.

EUROPEAN HEART JOURNAL (2021)

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Review Medicine, General & Internal

State of the art approach to managing angina and ischemia: tailoring treatment to the evidence

A. J. Manolis et al.

Summary: Stable angina is a chronic and often debilitating condition that affects patients' daily activities and quality of life. Current treatment guidelines consider hemodynamic variables and left ventricular dysfunction, but patients often have comorbidities and risk factors. A tailored approach may offer additional benefits for patients beyond angina relief.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2021)

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Article Peripheral Vascular Disease

Occupational Physical Activity and New-Onset Hypertension: A Nationwide Cohort Study in China

Qinqin Li et al.

Summary: The study found that there is a L-shaped association between occupational physical activity (OPA) and new-onset hypertension in males, and a U-shaped association in females. Moderate OPA in terms of both duration and intensity is associated with a lower risk of new-onset hypertension among both males and females, whereas heavy OPA was related to increased risk of new-onset hypertension in females.

HYPERTENSION (2021)

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Review Peripheral Vascular Disease

Evaluation of the Accuracy of Cuffless Blood Pressure Measurement Devices: Challenges and Proposals

Ramakrishna Mukkamala et al.

Summary: Novel cuffless wearable devices and smartphone applications claiming to measure blood pressure have gained popularity among healthcare professionals and patients, despite serious concerns about their accuracy and validation challenges. Existing standards for automated BP measurement devices are not suitable for cuffless devices, leading to potentially misleading conclusions in published data. Further research is needed to evaluate the capabilities and limitations of these emerging technologies.

HYPERTENSION (2021)

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Editorial Material Peripheral Vascular Disease

Missing Verification of Source Data in Hypertension Research: The HYGIA PROJECT in Perspective

Mattias Brunstrom et al.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Mean Arterial Pressure and Chronic Kidney Disease Progression in the CKiD Cohort

Janis M. Dionne et al.

Summary: In children with moderate CKD, the association between MAP percentile and disease progression risk was not significant until after 4 years of follow-up for those with nonglomerular CKD. On the other hand, in those with glomerular CKD, the differential risk for progression was observed from baseline with the highest risk in those with MAP >90th percentile. These relationships remained significant even after adjustment for proteinuria levels.

HYPERTENSION (2021)

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Letter Peripheral Vascular Disease

Clinical Phenotype of Resistant Hypertension Responders to Continuous Positive Airway Pressure Treatment: Results From the HIPARCO Randomized Clinical Trial

Miguel Angel Martinez-Garcia et al.

HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Identifying the predictive effectiveness of a genetic risk score for incident hypertension using machine learning methods among populations in rural China

Miaomiao Niu et al.

Summary: The study highlights the significant role of genetic information in improving the prediction of incident hypertension, especially when machine learning methods are utilized. The models incorporating the polygenic risk score (PGGRS) showed superior predictive ability compared to traditional models, indicating the potential of genetic information in identifying new hypertension cases using machine learning approaches.

HYPERTENSION RESEARCH (2021)

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Article Peripheral Vascular Disease

Hypertension and heart failure with preserved ejection fraction: position paper by the European Society of Hypertension

Alexandros Kasiakogias et al.

Summary: Hypertension is a major risk factor for HFpEF, and while specific guideline-directed medical therapy is not established, control of blood pressure is widely regarded as central to prevention and clinical care.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Hypertension in kidney transplantation: a consensus statement of the 'hypertension and the kidney' working group of the European Society of Hypertension

Jean-Michel Halimi et al.

Summary: Hypertension is common in kidney transplant recipients and may be difficult to treat. Current evidence suggests calcium channel blockers could be the preferred first-step antihypertensive agents in kidney transplant patients, while no clear benefit is documented for renin-angiotensin system inhibitor use over conventional treatment in the current literature. Randomized control trials demonstrating the clinical benefits of BP lowering on kidney and major cardiovascular events and recording patient-related outcomes are still needed.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension

Gianfranco Parati et al.

Summary: This paper provides an update on home blood pressure monitoring recommendations from the European Society of Hypertension (ESH) Working Group, taking into account new evidence and technological developments over the past 20 years. It has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.

JOURNAL OF HYPERTENSION (2021)

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Article Peripheral Vascular Disease

European Society of Hypertension position paper on renal denervation 2021

Roland E. Schmieder et al.

Summary: This paper presents updated recommendations based on new pivotal sham-controlled randomized clinical trials, demonstrating the efficacy and safety of endovascular device-based renal denervation for hypertension treatment. Meta-analyses show a significant reduction in blood pressure and a decreased incidence of cardiovascular events with this treatment option.

JOURNAL OF HYPERTENSION (2021)

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Editorial Material Peripheral Vascular Disease

The association between isolated systolic or diastolic hypertension and cardiovascular risk

Shikai Yu et al.

JOURNAL OF HYPERTENSION (2021)

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Article Medicine, General & Internal

Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis

Philip Joseph et al.

Summary: Fixed-dose combination treatment strategies significantly reduce the incidence of cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention, regardless of cardiometabolic risk factors.

LANCET (2021)

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Article Medicine, General & Internal

Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial

Clara K. Chow et al.

Summary: The QUARTET study in Australian adults with hypertension showed that early treatment with a fixed-dose quadruple quarter-dose combination achieved and maintained greater blood pressure lowering compared with starting with monotherapy.

LANCET (2021)

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Article Medicine, General & Internal

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

Bin Zhou et al.

Summary: Global prevalence of hypertension doubled from 1990 to 2019, with significant improvements in detection, treatment, and control rates. In 2019, 59% of women and 49% of men with hypertension were previously diagnosed, while treatment rates were 47% for women and 38% for men, with control rates at 23% for women and 18% for men. Disparities exist across countries, with some middle-income nations now outperforming high-income countries in hypertension management.

LANCET (2021)

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Review Cardiac & Cardiovascular Systems

Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension

Bin Zhou et al.

Summary: This review summarizes the global epidemiology of hypertension and blood pressure, highlighting the higher prevalence of hypertension in low and middle-income countries compared to high-income countries. The review also discusses the disparities in hypertension treatment across countries and the factors influencing these disparities.

NATURE REVIEWS CARDIOLOGY (2021)

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Review Urology & Nephrology

Hypertension-induced cognitive impairment: from pathophysiology to public health

Zoltan Ungvari et al.

Summary: Hypertension has significant impacts on cerebral microcirculation which can lead to cognitive impairment, especially in the elderly. Interventions targeting blood pressure reduction, lifestyle changes, and promoting microvascular health have the potential to prevent or delay vascular cognitive impairment and Alzheimer's disease in hypertensive patients.

NATURE REVIEWS NEPHROLOGY (2021)

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Article Medicine, General & Internal

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes

Bertram Pitt et al.

Summary: Finerenone therapy improved cardiovascular outcomes in patients with type 2 diabetes and stage 2 to 4 CKD with moderately elevated albuminuria or stage 1 or 2 CKD with severely elevated albuminuria, compared to placebo. The risk of the primary outcome event was significantly lower in the finerenone group, primarily driven by a reduction in hospitalization for heart failure.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension

Weili Zhang et al.

Summary: In 8511 Chinese patients aged 60 to 80 with hypertension, intensive treatment with a systolic blood-pressure target of 110 to <130 mm Hg resulted in a lower incidence of cardiovascular events compared to standard treatment with a target of 130 to <150 mm Hg. Except for a higher incidence of hypotension, the two groups had similar rates of adverse events.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Empagliflozin in Heart Failure with a Preserved Ejection Fraction

Stefan D. Anker et al.

Summary: Empagliflozin reduces the risk of cardiovascular death or hospitalization for heart failure in patients with heart failure and a preserved ejection fraction, regardless of the presence or absence of diabetes.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

Effect of Salt Substitution on Cardiovascular Events and Death

B. Neal et al.

Summary: The study found that among individuals with a history of stroke or aged 60 or older with high blood pressure, using a salt substitute can reduce the rates of stroke, major cardiovascular events, and death.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Public, Environmental & Occupational Health

Adherence to antihypertensive medications for secondary prevention of cardiovascular disease events: a dose-response meta-analysis

Y. Feng et al.

Summary: This study found a negative association between adherence to antihypertensive medications and the risk of recurrence of cardiovascular disease events, with higher adherence associated with lower risk. Additionally, for every 20% increase in adherence, the risk of cardiovascular disease events decreased by 9%. Results of sensitivity analysis and subgroup analysis were consistent.

PUBLIC HEALTH (2021)

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Review Clinical Neurology

Efficacy of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH): Systematic review and meta-analysis

Gonzalo Labarca et al.

Summary: CPAP therapy can significantly improve blood pressure, especially nighttime blood pressure, in patients with both OSA and RH.

SLEEP MEDICINE REVIEWS (2021)

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Review Obstetrics & Gynecology

Assisted reproductive technology and hypertensive disorders of pregnancy: systematic review and meta-analyses

Hui Ju Chih et al.

Summary: This study found through systematic review and meta-analysis that pregnancies conceived through assisted reproductive technology (ART) are more likely to develop hypertensive disorders of pregnancy (HDP) and preeclampsia compared to pregnancies from spontaneous conception (SC), especially in cases of frozen embryo transfer and oocyte donation.

BMC PREGNANCY AND CHILDBIRTH (2021)

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Review Medicine, General & Internal

Long covid-mechanisms, risk factors, and management

Harry Crook et al.

Summary: The long-term effects of covid-19 can affect multiple systems in the body, leading to persistent symptoms that impact patients of varying severity. These symptoms include fatigue, dyspnea, and cognitive impairment, among others. Studies discuss risk factors for acute and long covid, as well as potential therapeutic options.

BMJ-BRITISH MEDICAL JOURNAL (2021)

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Review Cardiac & Cardiovascular Systems

Sodium-Glucose Co-Transporter Inhibitors and Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Arjun K. Pandey et al.

Summary: SGLT inhibitors may reduce AF events and are likely to have a similar reducing effect on heart failure hospitalization/cardiovascular death in patients with and without AF histories.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

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Article Cardiac & Cardiovascular Systems

Pacemaker-Based Cardiac Neuromodulation Therapy in Patients With Hypertension: A Pilot Study

Zbigniew Kalarus et al.

Summary: Cardiac neuromodulation therapy showed significant reduction in systolic blood pressure among hypertensive patients with an indication for a pacemaker, especially in those with isolated systolic hypertension.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

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Article Pharmacology & Pharmacy

High Prevalence of Multimorbidity and Polypharmacy in Elderly Patients With Chronic Pain Receiving Home Care are Associated With Multiple Medication-Related Problems

Juliana Schneider et al.

Summary: The study found that multimorbidity and polypharmacy are highly prevalent in elderly outpatients receiving home care, with potential medication-related problems including potentially relevant drug interactions, overprescribing, and underuse.

FRONTIERS IN PHARMACOLOGY (2021)

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Review Physiology

Post-exercise Hypotension Following a Single Bout of High Intensity Interval Exercise vs. a Single Bout of Moderate Intensity Continuous Exercise in Adults With or Without Hypertension: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Isabela Roque Marcal et al.

Summary: Post-exercise hypotension (PEH) is an important tool for managing hypertension, with high-intensity interval exercise (HIIE) showing a greater reduction in blood pressure during daytime ambulatory monitoring compared to moderate-intensity continuous exercise (MICE). Further studies are needed to confirm HIIE's superiority as a safe intervention for lowering blood pressure, particularly in older individuals with hypertension.

FRONTIERS IN PHYSIOLOGY (2021)

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Article Medicine, General & Internal

Clinical features and predictors of masked uncontrolled hypertension from the Korean Ambulatory Blood Pressure Monitoring Registry

Hyun-Jin Kim et al.

Summary: This study aimed to investigate the clinical characteristics and predictors of masked uncontrolled hypertension (MUCH) in patients with hypertension. Patients with MUCH had worse metabolic profiles, higher office BP, and lower antihypertensive drug use compared to controlled hypertension patients. The study identified high office systolic and diastolic BP, prior stroke, dyslipidemia, LVH, high heart rate, and single antihypertensive drug use as independent predictors of MUCH, and proposed a prediction model with high diagnostic accuracy.

KOREAN JOURNAL OF INTERNAL MEDICINE (2021)

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Review Medicine, General & Internal

The Antihypertensive Effects and Safety of LCZ696 in Patients with Hypertension: A Systemic Review and Meta-Analysis of Randomized Controlled Trials

Su-Kiat Chua et al.

Summary: LCZ696 may reduce blood pressure more efficaciously than traditional therapy in hypertensive patients without increasing adverse effects.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Medicine, General & Internal

Clinical Characteristics and Predictors of All-Cause Mortality in Patients with Hypertensive Urgency at an Emergency Department

Jeong-Hun Shin et al.

Summary: This study investigated the characteristics and predictors of all-cause mortality in Korean emergency patients with hypertensive urgency, finding a 3-year all-cause mortality rate of 12.1% along with higher rates of emergency department revisits and readmission among non-survivors. Age over 60, male sex, history of chronic kidney disease, and proteinuria were identified as independent predictors of 3-year all-cause mortality.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article Computer Science, Interdisciplinary Applications

Study on artificial intelligence: The state of the art and future prospects

Caiming Zhang et al.

Summary: This study explores popular articles related to artificial intelligence published in recent years in order to provide a review of AI based on industry information integration. It clarifies the current state of the art of AI and aims to contribute important insights for future research. The main contribution is providing a clear overview of the scope of AI for practitioners in the real world.

JOURNAL OF INDUSTRIAL INFORMATION INTEGRATION (2021)

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Article Clinical Neurology

Association of Angiotensin II-Stimulating Antihypertensive Use and Dementia Risk Post Hoc Analysis of the PreDIVA Trial

Jan Willem van Dalen et al.

Summary: This study aimed to compare the impact of different antihypertensive drugs on dementia in older adults, finding that individuals using angiotensin II-stimulating antihypertensives had a lower risk of dementia, supporting the angiotensin hypothesis.

NEUROLOGY (2021)

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Article Urology & Nephrology

Diagnostic Performance of Office versus Ambulatory Blood Pressure in Kidney Transplant Recipients

Maria Korogiannou et al.

Summary: ABPM shows higher accuracy in determining hypertension prevalence and blood pressure control in kidney transplant recipients, while office BP has a higher rate of misclassification. These findings call for a broader use of ABPM in kidney transplant recipients.

AMERICAN JOURNAL OF NEPHROLOGY (2021)

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Article Geriatrics & Gerontology

Observed and expected serious adverse event rates in randomised clinical trials for hypertension: an observational study comparing trials that do and do not focus on older people

Peter Hanlon et al.

Summary: The rates of serious adverse events in trials focusing on older people are higher than in standard trials, but lower compared to the hospitalization and death rates in community patients with hypertension receiving similar treatments, indicating that clinical trials may not fully represent real-world clinical scenarios.

LANCET HEALTHY LONGEVITY (2021)

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Article Peripheral Vascular Disease

Dapagliflozin decreases ambulatory central blood pressure and pulse wave velocity in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial

Eirini Papadopoulou et al.

Summary: The study showed that dapagliflozin significantly reduced 24-hour brachial and central blood pressure levels, as well as arterial stiffness parameters in patients with type-2 diabetes mellitus, contributing positively to cardiovascular benefits.

JOURNAL OF HYPERTENSION (2021)

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Article Rheumatology

Cardiovascular risk factors in gout, psoriatic arthritis, rheumatoid arthritis and ankylosing spondylitis: a cross-sectional survey of patients in Western Sweden

Anton Jonatan Landgren et al.

Summary: The study aimed to compare traditional cardiovascular risk factors among patients with different rheumatic diseases, and found that hypertension was the most common comorbidity, with patients with gout having the highest prevalence of traditional CVRFs. Significant differences in occurrence of CVRFs by sex were also observed among patients with PsA, RA and AS.

RMD OPEN (2021)

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Article Clinical Neurology

European Stroke Organisation (ESO) guidelines on blood pressure management in acute ischaemic stroke and intracerebral haemorrhage

Else Charlotte Sandset et al.

Summary: The optimal blood pressure management in acute ischaemic stroke and acute intracerebral haemorrhage remains controversial, and the ESO guidelines offer evidence-based recommendations. Expert consensus statements provide additional guidance in cases where there is insufficient evidence to make recommendations.

EUROPEAN STROKE JOURNAL (2021)

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Review Nutrition & Dietetics

Mediterranean diet and blood pressure reduction in adults with and without hypertension: A systematic review and meta-analysis of randomized controlled trials

Christina D. Filippou et al.

Summary: This study comprehensively assessed the effects of the Mediterranean diet on blood pressure levels through a meta-analysis of 35 randomized controlled trials. The findings suggest that the Mediterranean diet may lead to a small but significant reduction in blood pressure compared to usual and other active intervention diets, with greater effects observed in trials with higher baseline blood pressure and longer follow-up durations.

CLINICAL NUTRITION (2021)

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Review Respiratory System

The safety of cardioselective β1-blockers in asthma: literature review and search of global pharmacovigilance safety reports

Miriam Bennett et al.

Summary: This study found no evidence of cardioselective beta(1)-blockers causing severe asthma or death. Observational data suggests that the use of cardioselective beta(1)-blockers is not associated with exacerbation of asthma. Only one report of asthma death potentially linked to cardioselective beta(1)-blockers was found in the VigiBase search.

ERJ OPEN RESEARCH (2021)

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Article Peripheral Vascular Disease

The corona-virus disease 2019 pandemic compromised routine care for hypertension: a survey conducted among excellence centers of the European Society of Hypertension

Thomas Weber et al.

Summary: The study revealed compromised patient care in hypertension Excellence Centers during the Covid-19 pandemic-related shutdown. The number of patients receiving treatment decreased significantly, with limited access to medical consultations reported by a majority of patients. Developing new strategies for hypertension care, including virtual clinics, is essential to maintain services during challenging times.

JOURNAL OF HYPERTENSION (2021)

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Article Clinical Neurology

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

Eivind Berge et al.

Summary: Intravenous thrombolysis is the approved systemic reperfusion treatment for acute ischaemic stroke patients, with the ESO guidelines providing evidence-based recommendations. The guidelines highlight the importance of timely thrombolysis within 4.5 hours for improving functional outcomes, and recommend its use for specific patient subgroups such as those waking from sleep.

EUROPEAN STROKE JOURNAL (2021)

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Review Sport Sciences

Do the combined blood pressure effects of exercise and antihypertensive medications add up to the sum of their parts? A systematic meta-review

Linda S. Pescatello et al.

Summary: The study compared the effects of exercise alone, medication alone, and combined on blood pressure in adults with hypertension. The results showed that both exercise alone and medication alone can reduce blood pressure, with the combined use enhancing the antihypertensive effects of medication.

BMJ OPEN SPORT & EXERCISE MEDICINE (2021)

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Article Public, Environmental & Occupational Health

Use of Hydrochlorothiazide and Risk of Melanoma and Nonmelanoma Skin Cancer

Julie Rouette et al.

Summary: Hydrochlorothiazide use is associated with an increased risk of cSCC, with evidence of a duration- and dose-response relationship; however, there is no association with an increased risk of BCC or melanoma.

DRUG SAFETY (2021)

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Review Pharmacology & Pharmacy

Pharmacist Interventions in the Management of Blood Pressure Control and Adherence to Antihypertensive Medications: A Systematic Review of Randomized Controlled Trials

Landon Reeves et al.

Summary: Pharmacist-led interventions have shown significant improvements in blood pressure control and medication adherence among patients with hypertension, utilizing methods such as medication counseling, patient education, and individualized care plans.

JOURNAL OF PHARMACY PRACTICE (2021)

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Review Rheumatology

Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout

Romy Hansildaar et al.

Summary: It is increasingly recognized that patients with rheumatoid arthritis and gout have an increased risk of cardiovascular disease. Systemic inflammation plays an important role in the pathophysiology of both diseases, and the benefits of urate-lowering therapy on cardiovascular outcomes remain controversial.

LANCET RHEUMATOLOGY (2021)

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Review Cardiac & Cardiovascular Systems

Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine

Rajiv Agarwal et al.

Summary: This review summarizes the development of mineralocorticoid receptor antagonists over the past 80 years, focusing on the mechanisms of action and advantages of nonsteroidal MRAs.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

A cohort study and meta-analysis of isolated diastolic hypertension: searching for a threshold to guide treatment

Alan P. Jacobsen et al.

Summary: The IDH defined by the 2017 ACC/AHA criteria is not consistently associated with CAC or CVD events, suggesting that a focus on healthy lifestyle instead of drug therapy may be sufficient for middle-aged or older adults meeting the criteria. More studies are needed to explore the potential associations in younger adults under 40 years old.

EUROPEAN HEART JOURNAL (2021)

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Article Cardiac & Cardiovascular Systems

Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromso Study

Ekaterina Sharashova et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Prediction of individualized lifetime benefit from cholesterol lowerirg, blood pressure lowering, antithrombotic therapy, and smokirg cessation in apparently healthy people

Nicole E. M. Jaspers et al.

EUROPEAN HEART JOURNAL (2020)

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Review Transplantation

Comparative effectiveness of different antihypertensive agents in kidney transplantation: a systematic review and meta-analysis

Anna Pisano et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2020)

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Article Cardiac & Cardiovascular Systems

2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

Francesco Cosentino et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Limited reproducibility of MUCH and WUCH: evidence from the ELSA study

Giuseppe Mancia et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)

Francois Mach et al.

EUROPEAN HEART JOURNAL (2020)

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Article Peripheral Vascular Disease

Hypertensive emergencies and urgencies: a single-centre experience in Northern Italy 2008-2015

Massimo Salvetti et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Lancet Commission on Hypertension group position statement on the global improvement of accuracy standards for devices that measure blood pressure

James E. Sharman et al.

JOURNAL OF HYPERTENSION (2020)

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Article Cardiac & Cardiovascular Systems

The impact of systolic and diastolic blood pressure variability on mortality is age dependent: Data from the Dublin Outcome Study

Grzegorz Bilo et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

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Review Cardiac & Cardiovascular Systems

The effect of exercise training on blood pressure in African and Asian populations: A systematic review and meta-analysis of randomized controlled trials

Marina Bersaoui et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

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Article Peripheral Vascular Disease

Influence of Renal Transplantation and Living Kidney Donation on Large Artery Stiffness and Peripheral Vascular Resistance

Niels H. Buus et al.

AMERICAN JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Accounting for Blood Pressure Seasonality Alters Evaluation of Practice-Level Blood Pressure Control Intervention

Thomas Gepts et al.

AMERICAN JOURNAL OF HYPERTENSION (2020)

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Article Medicine, General & Internal

Diagnosis and treatment of hypertensive emergencies and urgencies among Italian emergency and intensive care departments. Results from an Italian survey: Progetto GEAR (Gestione dell'Emergenza e urgenza in ARea critica)

F. Saladini et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2020)

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Review Peripheral Vascular Disease

Prognostic value of office blood pressure measurement in patients with atrial fibrillation on anticoagulation therapy: systematic review and meta-analysis

Anastasios Kollias et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Prevalence of isolated nocturnal hypertension according to 2018 European Society of Cardiology and European Society of Hypertension office blood pressure categories

Martin R. Salazar et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

STRIDE BP: an international initiative for accurate blood pressure measurement

George S. Stergiou et al.

JOURNAL OF HYPERTENSION (2020)

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Review Public, Environmental & Occupational Health

Efficacy of empowerment strategies for patients with hypertension: A systematic review and meta-analysis

Jingying Zhao et al.

PATIENT EDUCATION AND COUNSELING (2020)

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Article Cardiac & Cardiovascular Systems

Comparative efficacy of exercise and anti-hypertensive pharmacological interventions in reducing blood pressure in people with hypertension: A network meta-analysis

Chris Noone et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Race and Sex Differences in Modifiable Risk Factors and Incident Heart Failure

Danielle M. Kubicki et al.

JACC-HEART FAILURE (2020)

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Review Anesthesiology

Perioperative blood pressure in the elderly

Katherine Kozarek et al.

CURRENT OPINION IN ANESTHESIOLOGY (2020)

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Editorial Material Cardiac & Cardiovascular Systems

The muddy waters of the J-curve and coronary revascularization

Franz H. Messerli et al.

EUROPEAN HEART JOURNAL (2020)

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Article Peripheral Vascular Disease

Aortic pulse wave velocity in individuals of Asian and African ancestry: the HELISUR study

Frederieke S. Diemer et al.

JOURNAL OF HUMAN HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Elevated Blood Pressure in the Emergency Department A Risk Factor for Incident Cardiovascular Disease

Pontus Oras et al.

HYPERTENSION (2020)

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Review Peripheral Vascular Disease

Medical Therapies for Heart Failure With Preserved Ejection Fraction

Sverre E. Kjeldsen et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Association of Extreme Nocturnal Dipping With Cardiovascular Events Strongly Depends on Age

Paolo Palatini et al.

HYPERTENSION (2020)

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Article Neurosciences

Longer Duration of Hypertension and MRI Microvascular Brain Alterations Are Associated with Lower Hippocampal Volumes in Older Individuals with Hypertension

Areti Triantafyllou et al.

JOURNAL OF ALZHEIMERS DISEASE (2020)

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Article Peripheral Vascular Disease

Left ventricular hypertrophy in isolated and dual masked hypertension

Cesare Cuspidi et al.

JOURNAL OF CLINICAL HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Recommendations for blood pressure measurement in large arms in research and clinical practice: position paper of the European society of hypertension working group on blood pressure monitoring and cardiovascular variability

Paolo Palatini et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Atrial fibrillation and the risk of cardiovascular disease and mortality in the Hypertension in the Very Elderly Trial

Riitta L. Antikainen et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Seasonal variation in blood pressure: Evidence, consensus and recommendations for clinical practice. Consensus statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability

George S. Stergiou et al.

JOURNAL OF HYPERTENSION (2020)

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Review Peripheral Vascular Disease

Hypertensive emergencies and urgencies in emergency departments: a systematic review and meta-analysis

Anna Astarita et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Update of the position paper on arterial hypertension and erectile dysfunction

Margus Viigimaa et al.

JOURNAL OF HYPERTENSION (2020)

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Review Cardiac & Cardiovascular Systems

Salt Reduction to Prevent Hypertension and Cardiovascular Disease JACC State-of-the-Art Review

Feng J. He et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Trajectories of Age-Related Arterial Stiffness in Chinese Men and Women

Yao Lu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

The real world use of combined P-glycoprotein and moderate CYP3A4 inhibitors with rivaroxaban or apixaban increases bleeding

Sarah Hanigan et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2020)

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Review Medicine, General & Internal

Treating Hypertension in Chronic Obstructive Pulmonary Disease

Shannon W. Finks et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Review Pharmacology & Pharmacy

Questionnaires on adherence to antihypertensive treatment: a systematic review of published questionnaires and their psychometric properties

Elisa Pareja-Martinez et al.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACY (2020)

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Article Cardiac & Cardiovascular Systems

Sex Differences in Blood Pressure Trajectories Over the Life Course

Hongwei Ji et al.

JAMA CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Peripartum management of hypertension: a position paper of the ESC Council on Hypertension and the European Society of Hypertension

Renata Cifkova et al.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2020)

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Review Nutrition & Dietetics

Effects of Popular Diets on Anthropometric and Cardiometabolic Parameters: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials

Monica Dinu et al.

ADVANCES IN NUTRITION (2020)

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Review Medicine, General & Internal

Effect of dose and duration of reduction in dietary sodium on blood pressure levels: systematic review and meta-analysis of randomised trials

Liping Huang et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Hypertension Canada's 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children

Doreen M. Rabi et al.

CANADIAN JOURNAL OF CARDIOLOGY (2020)

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Review Cardiac & Cardiovascular Systems

Hypertension, the renin-angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19

Reinhold Kreutz et al.

CARDIOVASCULAR RESEARCH (2020)

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Article Cardiac & Cardiovascular Systems

Cardiovascular Risk of Isolated Systolic or Diastolic Hypertension in Young Adults

Hokyou Lee et al.

CIRCULATION (2020)

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Article Endocrinology & Metabolism

The Influence of Baseline Diastolic Blood Pressure on the Effects of Intensive Blood Pressure Lowering on Cardiovascular Outcomes and All-Cause Mortality in Type 2 Diabetes

Olesya L. Ilkun et al.

DIABETES CARE (2020)

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Review Cardiac & Cardiovascular Systems

Arterial Stiffness and Cognition Among Adults: A Systematic Review and Meta-Analysis of Observational and Longitudinal Studies

Celia Alvarez-Bueno et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Medicine, General & Internal

Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension

George Hripcsak et al.

JAMA INTERNAL MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Cardiovascular outcomes, bleeding risk, and achieved blood pressure in patients on long-term anticoagulation with the thrombin antagonist dabigatran or warfarin: data from the RE-LY trial

Michael Boehm et al.

EUROPEAN HEART JOURNAL (2020)

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Review Pathology

Cystatin C as a biomarker of chronic kidney disease: latest developments

Stefanie W. Benoit et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2020)

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Review Peripheral Vascular Disease

Orthostatic Hypertension Critical Appraisal of an Overlooked Condition

Jens Jordan et al.

HYPERTENSION (2020)

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Review Peripheral Vascular Disease

Masked and white coat hypertension, the double trouble of large arteries: A systematic review and meta-analysis

Christina Antza et al.

JOURNAL OF CLINICAL HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Coronary artery calcium scoring in patients with hypertension

Richard L. Weinberg et al.

JOURNAL OF HUMAN HYPERTENSION (2020)

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Review Peripheral Vascular Disease

Sympathetic neural abnormalities in type 1 and type 2 diabetes: a systematic review and meta-analysis

Guido Grassi et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Genetics, diagnosis, management and future directions of research of phaeochromocytoma and paraganglioma: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension

Jacques W. M. Lenders et al.

JOURNAL OF HYPERTENSION (2020)

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Review Cardiac & Cardiovascular Systems

Review and meta-analysis of renal artery damage following percutaneous renal denervation with radiofrequency renal artery ablation

Raymond R. Townsend et al.

EUROINTERVENTION (2020)

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Review Nutrition & Dietetics

Dietary Approaches to Stop Hypertension (DASH) Diet and Blood Pressure Reduction in Adults with and without Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Christina D. Filippou et al.

ADVANCES IN NUTRITION (2020)

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Article Cardiac & Cardiovascular Systems

Association Between Road Traffic Noise and Incidence of Diabetes Mellitus and Hypertension in Toronto, Canada: A Population-Based Cohort Study

Saeha Shin et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Medicine, General & Internal

Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial

Michael Bohm et al.

LANCET (2020)

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Review Cardiac & Cardiovascular Systems

Device-based therapies for arterial hypertension

Lucas Lauder et al.

NATURE REVIEWS CARDIOLOGY (2020)

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Article Medicine, General & Internal

Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19

Giuseppe Mancia et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19

Harmony R. Reynolds et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Review Nutrition & Dietetics

Adherence to the dietary approaches to stop hypertension (DASH) diet in relation to all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective cohort studies

Sepideh Soltani et al.

NUTRITION JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients

Peter Willeit et al.

CIRCULATION (2020)

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Article Cardiac & Cardiovascular Systems

Phosphodiesterase 3A and Arterial Hypertension

Maria Ercu et al.

CIRCULATION (2020)

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Article Medicine, General & Internal

Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

Claudio Borghi et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2020)

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Article Peripheral Vascular Disease

Pregnancy-Related Complications in Patients With Fibromuscular Dysplasia A Report From the European/International Fibromuscular Dysplasia Registry

Marco Pappaccogli et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Antihypertensive Treatment in Elderly Frail Patients Evidence From a Large Italian Database

Federico Rea et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Association Between the European Society of Cardiology/European Society of Hypertension Heart Rate Thresholds for Cardiovascular Risk and Neuroadrenergic Markers

Guido Grassi et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Association of Hypertension and Blood Pressure With Kidney Cancer Risk A Nationwide Population-Based Cohort Study

Chang Seong Kim et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Cardiovascular Event Risks Associated With Masked Nocturnal Hypertension Defined by Home Blood Pressure Monitoring in the J-HOP Nocturnal Blood Pressure Study

Takeshi Fujiwara et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

2020 International Society of Hypertension Global Hypertension Practice Guidelines

Thomas Unger et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Nonvalidated Home Blood Pressure Devices Dominate the Online Marketplace in Australia Major Implications for Cardiovascular Risk Management

Dean S. Picone et al.

HYPERTENSION (2020)

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Review Cardiac & Cardiovascular Systems

Potassium Intake and Blood Pressure: A Dose-Response Meta-Analysis of Randomized Controlled Trials

Tommaso Filippini et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Medicine, General & Internal

Association of Oral Anticoagulants and Verapamil or Diltiazem With Adverse Bleeding Events in Patients With Nonvalvular Atrial Fibrillation and Normal Kidney Function

Phuong Pham et al.

JAMA NETWORK OPEN (2020)

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Review Peripheral Vascular Disease

Circadian variations in blood pressure and their implications for the administration of antihypertensive drugs: is dosing in the evening better than in the morning?

Michel Burnier et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Beta-blockers in hypertension: overview and meta-analysis of randomized outcome trials

Costas Thomopoulos et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Subtype diagnosis, treatment, complications and outcomes of primary aldosteronism and future direction of research: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension*

Paolo Mulatero et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Nocturnal blood pressure: the dark side of white-coat hypertension

Cesare Cuspidi et al.

JOURNAL OF HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension*

Paolo Mulatero et al.

JOURNAL OF HYPERTENSION (2020)

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Article Medicine, General & Internal

Three-Year Outcomes of Bariatric Surgery in Patients With Obesity and Hypertension A Randomized Clinical Trial

Carlos A. Schiavon et al.

ANNALS OF INTERNAL MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Association of Hypertension and Arterial Blood Pressure on Limb and Cardiovascular Outcomes in Symptomatic Peripheral Artery Disease The EUCLID Trial

Marat Fudim et al.

CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES (2020)

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Review Cardiac & Cardiovascular Systems

Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake

Martin O'Donnell et al.

EUROPEAN HEART JOURNAL (2020)

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Article Peripheral Vascular Disease

Isolated Diastolic Hypertension in the UK Biobank Comparison of ACC/AHA and ESC/NICE Guideline Definitions

Brian P. McGrath et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Discrimination and Hypertension Risk Among African Americans in the Jackson Heart Study

Allana T. Forde et al.

HYPERTENSION (2020)

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Article Peripheral Vascular Disease

Effects of Intensive Versus Standard Office-Based Hypertension Treatment Strategy on White-Coat Effect and Masked Uncontrolled Hypertension From the SPRINT ABPM Ancillary Study

Lama Ghazi et al.

HYPERTENSION (2020)

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Review Medicine, General & Internal

Sex differences in the adherence of antihypertensive drugs: a systematic review with meta-analyses

Annalisa Biffi et al.

BMJ OPEN (2020)

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Article Medicine, General & Internal

Association of bariatric surgery with all-cause mortality and incidence of obesity-related disease at a population level: A systematic review and meta-analysis

Tom Wiggins et al.

PLOS MEDICINE (2020)

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Review Medicine, General & Internal

Benefits and Risks of Bariatric Surgery in Adults A Review

David E. Arterburn et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Article Geriatrics & Gerontology

Generalizability of Blood Pressure Lowering Trials to Older Patients: Cross-Sectional Analysis

James P. Sheppard et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2020)

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Article Urology & Nephrology

Death after Kidney Transplantation: An Analysis by Era and Time Post-Transplant

Tracey Ying et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Review Medicine, General & Internal

Clinical efficacy and safety of spironolactone in patients with resistant hypertension A systematic review and meta-analysis

Cong Chen et al.

MEDICINE (2020)

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Article Medicine, General & Internal

Dapagliflozin in Patients with Chronic Kidney Disease

Hiddo J. L. Heerspink et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

George L. Bakris et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Medicine, General & Internal

Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes

Mihoko Yoshino et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Review Medicine, General & Internal

Antihypertensive therapies in moderate or severe aortic stenosis: a systematic review and meta-analysis

Jonathan Sen et al.

BMJ OPEN (2020)

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Review Cardiac & Cardiovascular Systems

Nonpharmacologic Interventions for Reducing Blood Pressure in Adults With Prehypertension to Established Hypertension

Jinming Fu et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Clinical Neurology

Outcomes of Intensive Systolic Blood Pressure Reduction in Patients With Intracerebral Hemorrhage and Excessively High Initial Systolic Blood Pressure Post Hoc Analysis of a Randomized Clinical Trial

Adnan I. Qureshi et al.

JAMA NEUROLOGY (2020)

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Review Cardiac & Cardiovascular Systems

Association of β-blocker use with survival and pulmonary function in patients with chronic obstructive pulmonary and cardiovascular disease: a systematic review and meta-analysis

Yan-Li Yang et al.

EUROPEAN HEART JOURNAL (2020)

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Article Medicine, General & Internal

Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk The STRENGTH Randomized Clinical Trial

Stephen J. Nicholls et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Letter Medicine, General & Internal

N-of-1 Trial of a Statin, Placebo, or No Treatment to Assess Side Effects

Frances A. Wood et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Review Environmental Sciences

Hypertension Prevalence Based on Blood Pressure Measurements on Two vs. One Visits: A Community-Based Screening Programme and a Narrative Review

Chloe Plumettaz et al.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2020)

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Review Cardiac & Cardiovascular Systems

Exercise Reduces Ambulatory Blood Pressure in Patients With Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Gonzalo Saco-Ledo et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Cardiac & Cardiovascular Systems

Spironolactone Use and Improved Outcomes in Patients With Heart Failure With Preserved Ejection Fraction With Resistant Hypertension

Tetsuro Tsujimoto et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Review Peripheral Vascular Disease

Amiloride: A review

Qianhui Sun et al.

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2020)

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Letter Medicine, General & Internal

Deprescribing Antihypertensive Medication in Elderly Adults

William B. Applegate et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

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Review Cardiac & Cardiovascular Systems

Cardiovascular effects of waterpipe smoking: a systematic review and meta-analysis

Radwan Al Ali et al.

REVIEWS IN CARDIOVASCULAR MEDICINE (2020)

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Review Peripheral Vascular Disease

Evidence and Recommendations on the Use of Telemedicine for the Management of Arterial Hypertension An International Expert Position Paper

Stefano Omboni et al.

HYPERTENSION (2020)

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Article Pediatrics

Labetalol-Induced Hepatotoxicity during Pregnancy: A Case Report

Anna Whelan et al.

AJP REPORTS (2020)

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Review Peripheral Vascular Disease

Isolated Nocturnal Hypertension: What Do We Know and What Can We Do?

Marijana Tadic et al.

INTEGRATED BLOOD PRESSURE CONTROL (2020)

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Review Medicine, General & Internal

Comparison of Cardiovascular Events Among Users of Different Classes of Antihypertension Medications A Systematic Review and Network Meta-analysis

Jingkai Wei et al.

JAMA NETWORK OPEN (2020)

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Review Cardiac & Cardiovascular Systems

Differences in Epidemiology and Risk Factors for Atrial Fibrillation Between Women and Men

Maryam Kavousi

FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)

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Article Cardiac & Cardiovascular Systems

Limited reproducibility of MUCH and WUCH: evidence from the ELSA study

Giuseppe Mancia et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Long-term blood pressure trajectories and incident atrial fibrillation in women and men: the Tromso Study

Ekaterina Sharashova et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Association of beta-blocker use with survival and pulmonary function in patients with chronic obstructive pulmonary and cardiovascular disease: a systematic review and meta-analysis

Yan-Li Yang et al.

EUROPEAN HEART JOURNAL (2020)

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Article Cardiac & Cardiovascular Systems

Guideline recommended treatment to targets of cardiovascular risk is inadequate in patients with inflammatory joint diseases

Eirik Ikdahl et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

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Article Peripheral Vascular Disease

Malignant hypertension: diagnosis, treatment and prognosis with experience from the Bordeaux cohort

Sebastien Rubin et al.

JOURNAL OF HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Large discrepancy between unobserved automated office blood pressure and ambulatory blood pressure in a high cardiovascular risk cohort

Jiwon Seo et al.

JOURNAL OF HYPERTENSION (2019)

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Article Obstetrics & Gynecology

Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, North American and Australian cohorts

S. Santos et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2019)

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Review Cardiac & Cardiovascular Systems

Vascular Cardio-Oncology: Vascular Endothelial Growth Factor inhibitors and hypertension

Jorie Versmissen et al.

CARDIOVASCULAR RESEARCH (2019)

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Article Cardiac & Cardiovascular Systems

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons

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CIRCULATION (2019)

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Review Cardiac & Cardiovascular Systems

Cardiovascular Disease-Related Morbidity and Mortality in Women With a History of Pregnancy Complications Systematic Review and Meta-Analysis

Sonia M. Grandi et al.

CIRCULATION (2019)

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Article Cardiac & Cardiovascular Systems

Cardio-Oncology: Vascular and Metabolic Perspectives A Scientific Statement From the American Heart Association

Umberto Campia et al.

CIRCULATION (2019)

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Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2019 Update A Report From the American Heart Association

Emelia J. Benjamin et al.

CIRCULATION (2019)

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Article Cardiac & Cardiovascular Systems

Prognostic Impact of β-Blocker Dose After Acute Myocardial Infarction

Doyeon Hwang et al.

CIRCULATION JOURNAL (2019)

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Article Cardiac & Cardiovascular Systems

Hypertension Management in Older and Frail Older Patients

Athanase Benetos et al.

CIRCULATION RESEARCH (2019)

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Review Cardiac & Cardiovascular Systems

Adherence in Hypertension A Review of Prevalence, Risk Factors, Impact, and Management

Michel Burnier et al.

CIRCULATION RESEARCH (2019)

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Article Cardiac & Cardiovascular Systems

Two-Drug Combinations as First-Step Antihypertensive Treatment

Giuseppe Mancia et al.

CIRCULATION RESEARCH (2019)

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Review Endocrinology & Metabolism

Ambulatory Blood Pressure Reduction With SGLT-2 Inhibitors: Dose-Response Meta-analysis and Comparative Evaluation With Low-Dose Hydrochlorothiazide

Panagiotis I. Georgianos et al.

DIABETES CARE (2019)

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Article Cardiac & Cardiovascular Systems

Control of blood pressure and risk of mortality in a cohort of older adults: the Berlin Initiative Study

Antonios Douros et al.

EUROPEAN HEART JOURNAL (2019)

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Article Cardiac & Cardiovascular Systems

Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry

Felix Mahfoud et al.

EUROPEAN HEART JOURNAL (2019)

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Article Peripheral Vascular Disease

Unattended Versus Attended Blood Pressure Measurement Relationship With Preclinical Organ Damage

Massimo Salvetti et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Prevalence of Apparent Treatment-Resistant Hypertension in the United States: Comparison of the 2008 and 2018 American Heart Association Scientific Statements on Resistant Hypertension

Robert M. Carey et al.

HYPERTENSION (2019)

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Article Medicine, General & Internal

Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia A Randomized Clinical Trial

Jeff D. Williamson et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

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Article Peripheral Vascular Disease

Seasonal variation in 24 h blood pressure profile in healthy adults- A prospective observational study

Abhishek Goyal et al.

JOURNAL OF HUMAN HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Association of orthostatic hypertension with mortality in the Systolic Hypertension in the Elderly Program

William J. Kostis et al.

JOURNAL OF HUMAN HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Association between central haemodynamics and risk of all-cause mortality and cardiovascular disease: a systematic review and meta-analysis

Wen-feng Li et al.

JOURNAL OF HUMAN HYPERTENSION (2019)

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Article Peripheral Vascular Disease

First international consensus on the diagnosis and management of fibromuscular dysplasia

Heather L. Gornik et al.

JOURNAL OF HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Short-termblood pressure variability outweighs average 24-h blood pressure in the prediction of cardiovascular events in hypertension of the young

Paolo Palatini et al.

JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Does the benefit from treating to lower blood pressure targets vary with age? A systematic review and meta-analysis

George C. Roush et al.

JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

The effect of SGLT-2 inhibitors on albuminuria and proteinuria in diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials

Alexia Piperidou et al.

JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Effects of isometric resistance training on resting blood pressure: individual participant data meta-analysis

Neil A. Smart et al.

JOURNAL OF HYPERTENSION (2019)

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Review Medicine, General & Internal

Gender equality in science, medicine, and global health: where are we at and why does it matter?

Geordan Shannon et al.

LANCET (2019)

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Article Medicine, General & Internal

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

Philip M. Bath et al.

LANCET (2019)

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Article Transplantation

SGLT-2 inhibitors and GLP-1 receptor agonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. A consensus statement by the EURECA-m and the DIABESITY working groups of the ERA-EDTA

Pantelis Sarafidis et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2019)

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Article Medicine, General & Internal

Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans

Dike B. Ojji et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Review Cardiac & Cardiovascular Systems

Cardiovascular effects of electronic cigarettes: A systematic review and meta-analysis

Georgia Skotsimara et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2019)

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Article Cardiac & Cardiovascular Systems

Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry

Kornelia Kotseva et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2019)

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Article Cardiac & Cardiovascular Systems

Detection of Left Ventricular Hypertrophy Using Bayesian Additive Regression Trees: The MESA (Multi-Ethnic Study of Atherosclerosis)

Rodney Sparapani et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)

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Article Cardiac & Cardiovascular Systems

Effect of Previous Exposure to Malaria on Blood Pressure in Kilifi, Kenya: A Mendelian Randomization Study

Anthony O. Etyang et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)

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Review Medicine, General & Internal

Comparing Automated Office Blood Pressure Readings With Other Methods of Blood Pressure Measurement for Identifying Patients With Possible Hypertension A Systematic Review and Meta-analysis

Michael Roerecke et al.

JAMA INTERNAL MEDICINE (2019)

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Article Nutrition & Dietetics

Dose-response relation between dietary sodium and blood pressure: a meta-regression analysis of 133 randomized controlled trials

Niels Graudal et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2019)

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Review Peripheral Vascular Disease

Targeting Nocturnal Hypertension: The Emerging Role of Home Blood Pressure

Cesare Cuspidi et al.

AMERICAN JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Clinical inertia in hypertension: a new holistic and practical concept within the cardiovascular continuum and clinical care process

Vicente Pallares-Carratala et al.

BLOOD PRESSURE (2019)

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Editorial Material Peripheral Vascular Disease

Validation protocols for blood pressure measuring devices: the impact of the European Society of Hypertension International Protocol and the development of a Universal Standard

Eoin O'Brien et al.

BLOOD PRESSURE MONITORING (2019)

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Review Clinical Neurology

Autoimmune autonomic neuropathies and ganglionopathies: epidemiology, pathophysiology, and therapeutic advances

Elisabeth P. Golden et al.

CLINICAL AUTONOMIC RESEARCH (2019)

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Article Cardiac & Cardiovascular Systems

Patient preference for therapies in hypertension: a cross-sectional survey of German patients

Roland E. Schmieder et al.

CLINICAL RESEARCH IN CARDIOLOGY (2019)

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Review Cardiac & Cardiovascular Systems

Significance of psychosocial factors in cardiology: update 2018 Position paper of the German Cardiac Society

Christian Albus et al.

CLINICAL RESEARCH IN CARDIOLOGY (2019)

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Review Peripheral Vascular Disease

Sleep and Resistant Hypertension

Mercedes R. Carnethon et al.

CURRENT HYPERTENSION REPORTS (2019)

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Article Cardiac & Cardiovascular Systems

Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study

Scott T. Chiesa et al.

EUROPEAN HEART JOURNAL (2019)

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Article Peripheral Vascular Disease

Comparison Between Home and Ambulatory Morning Blood Pressure and Morning Hypertension in Their Reproducibility and Associations With Vascular Injury

Qian-Hui Guo et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Antihypertensive Medication Nonpersistence and Low Adherence for Adults <65 Years Initiating Treatment in 2007-2014

Gabriel S. Tajeu et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Incidence, prevalence, and predictors of treatment-resistant hypertension with intensive blood pressure lowering

Steven M. Smith et al.

JOURNAL OF CLINICAL HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Impact of repeated blood pressure measurement on blood pressure categorization in a population-based study from India

Arun Pulikkottil Jose et al.

JOURNAL OF HUMAN HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Reviewing the effects of thiazide and thiazide-like diuretics as photosensitizing drugs on the risk of skin cancer

Reinhold Kreutz et al.

JOURNAL OF HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Perioperative SBP changes during orthopedic surgery in the elderly: clinical implications

Maria Koutsaki et al.

JOURNAL OF HYPERTENSION (2019)

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Article Transplantation

Cardiovascular disease in the kidney transplant recipient: epidemiology, diagnosis and management strategies

Janani Rangaswami et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2019)

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Article Medicine, General & Internal

Obstructive Sleep Apnea in Adults

Sigrid C. Veasey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Medicine, General & Internal

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

V. Perkovic et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Peripheral Vascular Disease

Directly observed therapy prior to ambulatory blood pressure measurement (DOT-HTN) in uncontrolled hypertensive patients - Effect on blood pressure, safety and patient perception

Ulla Hjornholm et al.

BLOOD PRESSURE (2019)

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Review Peripheral Vascular Disease

Home Blood Pressure Monitoring in Children and Adolescents: Systematic Review of Evidence on Clinical Utility

George Stergiou et al.

CURRENT HYPERTENSION REPORTS (2019)

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Article Peripheral Vascular Disease

Nighttime Blood Pressure Measured by Home Blood Pressure Monitoring as an Independent Predictor of Cardiovascular Events in General Practice: The J-HOP Nocturnal Blood Pressure Study

Kazuomi Kario et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Mortality Outcomes With Intensive Blood Pressure Targets in Chronic Kidney Disease Patients: A Pooled Individual Patient Data Analysis From Randomized Trials

Rahul Aggarwal et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Masked Uncontrolled Hypertension Is Not Attributable to Medication Nonadherence

Mohammed Siddiqui et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Ambulatory versus home blood pressure monitoring: frequency and determinants of blood pressure difference and diagnostic disagreement

Angeliki Ntineri et al.

JOURNAL OF HYPERTENSION (2019)

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Article Cardiac & Cardiovascular Systems

Vascular Cognitive Impairment and Dementia

Costantino Iadecola et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

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Article Sport Sciences

Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease

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MEDICINE & SCIENCE IN SPORTS & EXERCISE (2019)

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Article Medicine, General & Internal

Effect of Systolic and Diastolic Blood Pressure on Cardiovascular Outcomes

Alexander C. Flint et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Public, Environmental & Occupational Health

The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data

Sarah-Jo Sinnott et al.

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2019)

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Review Public, Environmental & Occupational Health

The cardiovascular effects of electronic cigarettes: A systematic review of experimental studies

Ciaran D. Kennedy et al.

PREVENTIVE MEDICINE (2019)

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Article Clinical Neurology

Effect of Standard vs Intensive Blood Pressure Control on the Risk of Recurrent Stroke A Randomized Clinical Trial and Meta-analysis

Kazuo Kitagawa et al.

JAMA NEUROLOGY (2019)

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Meeting Abstract Cardiac & Cardiovascular Systems

Sex-based differences in heart failure across the ejection fraction spectrum: phenotyping, prognostic and therapeutic implications

D. Stolfo et al.

EUROPEAN JOURNAL OF HEART FAILURE (2019)

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Review Peripheral Vascular Disease

Emergence of Home Blood Pressure-Guided Management of Hypertension Based on Global Evidence

Kazuomi Kario et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Impact of hypertension phenotypes on the office and 24-h pulse wave velocity and augmentation index in individuals with or without antihypertensive medication use

Annelise M. G. Paiva et al.

HYPERTENSION RESEARCH (2019)

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Article Medicine, General & Internal

Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes

Wen-Yi Yang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

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Article Peripheral Vascular Disease

A comparative meta-analysis of prospective observational studies on masked hypertension and masked uncontrolled hypertension defined by ambulatory and home blood pressure

Dong-Yan Zhang et al.

JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Blood pressure measurement in atrial fibrillation: review and meta-analysis of evidence on accuracy and clinical relevance

George S. Stergiou et al.

JOURNAL OF HYPERTENSION (2019)

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Article Medicine, General & Internal

Patiromer versus placebo to enable spironolactone use in patients with resistant hypertension and chronic kidney disease (AMBER): a phase 2, randomised, double-blind, placebo-controlled trial

Rajiv Agarwal et al.

LANCET (2019)

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Article Clinical Neurology

Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data

Tom J. Moullaali et al.

LANCET NEUROLOGY (2019)

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Review Medicine, General & Internal

Treatment of Hypertension in Patients with Asthma

Sandra C. Christiansen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Medicine, General & Internal

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction

S. D. Solomon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Editorial Material Multidisciplinary Sciences

Dosing time matters

Marc D. Ruben et al.

SCIENCE (2019)

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Editorial Material Medicine, General & Internal

Diagnosis and management of hypertension in pregnancy: summary of updated NICE guidance

Katie Webster et al.

BMJ-BRITISH MEDICAL JOURNAL (2019)

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Review Medicine, General & Internal

Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis

Ulf Ekelund et al.

BMJ-BRITISH MEDICAL JOURNAL (2019)

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Article Oncology

Prevalence of hypertension, diabetes, and dyslipidemia, and their additive effects on myocardial infarction and stroke: a cross-sectional study in Nanjing, China

Shan Lu et al.

ANNALS OF TRANSLATIONAL MEDICINE (2019)

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Letter Medicine, General & Internal

Cardiovascular Events and Mortality in White Coat Hypertension IN RESPONSE

Jordana B. Cohen et al.

ANNALS OF INTERNAL MEDICINE (2019)

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Article Oncology

Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case-control study

Anton Pottegard et al.

BRITISH JOURNAL OF CANCER (2019)

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Article Cardiac & Cardiovascular Systems

Effects of Intensive Versus Standard Ambulatory Blood Pressure Control on Cerebrovascular Outcomes in Older People (INFINITY)

William B. White et al.

CIRCULATION (2019)

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Review Peripheral Vascular Disease

Cost-Effectiveness and Challenges of Implementing Intensive Blood Pressure Goals and Team-Based Care

Catherine G. Derington et al.

CURRENT HYPERTENSION REPORTS (2019)

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Review Medicine, General & Internal

Evaluation, risk stratification and management of hypertensive patients in the perioperative period

Maria Koutsaki et al.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2019)

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Review Peripheral Vascular Disease

STRIDE BP international initiative for accurate blood pressure measurement: Systematic review of published validation studies of blood pressure measuring devices

George S. Stergiou et al.

JOURNAL OF CLINICAL HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Effects of dual blockade in heart failure and renal dysfunction: Systematic review and meta-analysis

Alessandra Rodrigues Silva et al.

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2019)

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Article Medicine, General & Internal

A community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial

Jon-David Schwalm et al.

LANCET (2019)

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Review Biochemistry & Molecular Biology

Sex differences in cardiometabolic disorders

Eva Gerdts et al.

NATURE MEDICINE (2019)

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Article Radiology, Nuclear Medicine & Medical Imaging

Left Ventricular Mass at MRI and Long-term Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis (MESA)

Nadine Kawel-Boehm et al.

RADIOLOGY (2019)

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Article Multidisciplinary Sciences

Low on-treatment diastolic blood pressure and cardiovascular outcome: A post-hoc analysis using NHLBI SPRINT Research Materials

Piotr Sobieraj et al.

SCIENTIFIC REPORTS (2019)

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Article Urology & Nephrology

Effect of Intensive Blood Pressure Lowering on Kidney Tubule Injury: Findings From the ACCORD Trial Study Participants

Girish N. Nadkarni et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2019)

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Article Cardiac & Cardiovascular Systems

Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project

Shiwani Mahajan et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2019)

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Review Sport Sciences

How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and medication effects on systolic blood pressure

Huseyin Naci et al.

BRITISH JOURNAL OF SPORTS MEDICINE (2019)

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Review Cardiac & Cardiovascular Systems

Change in Proteinuria or Albuminuria as a Surrogate for Cardiovascular and Other Major Clinical Outcomes: A Systematic Review and Meta-analysis

Tyrone G. Harrison et al.

CANADIAN JOURNAL OF CARDIOLOGY (2019)

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Article Cardiac & Cardiovascular Systems

Sustainability of Blood Pressure Reduction in Black Barbershops

Ronald G. Victor et al.

CIRCULATION (2019)

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Article Endocrinology & Metabolism

Rates of abnormal aldosterone/renin ratio in African-origin compared to European-origin patients: A retrospective study

Khalid S. Ahmed et al.

CLINICAL ENDOCRINOLOGY (2019)

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Article Pharmacology & Pharmacy

A Model-Based Meta-Analysis of 24 Antihyperglycemic Drugs for Type 2 Diabetes: Comparison of Treatment Effects at Therapeutic Doses

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CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)

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Editorial Material Peripheral Vascular Disease

Masked Uncontrolled Hypertension: Question of Too Much Daily Life Sympathetic Overdrive

Guido Grassi et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Out-of-Clinic Sympathetic Activity Is Increased in Patients With Masked Uncontrolled Hypertension

Mohammed Siddiqui et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Effects of Bariatric Surgery Versus Medical Therapy on the 24-Hour Ambulatory Blood Pressure and the Prevalence of Resistant Hypertension The GATEWAY Randomized Clinical Trial

Carlos A. Schiavon et al.

HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Nocturnal blood pressure measured by home devices: evidence and perspective for clinical application

Kei Asayama et al.

JOURNAL OF HYPERTENSION (2019)

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Review Peripheral Vascular Disease

Updated systematic review and meta-analysis on the role of isometric resistance training for resting blood pressure management in adults

Alejandro Lopez-Valenciano et al.

JOURNAL OF HYPERTENSION (2019)

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Article Peripheral Vascular Disease

Dose-Response Association Between Level of Physical Activity and Mortality in Normal, Elevated, and High Blood Pressure

Gowsini Joseph et al.

HYPERTENSION (2019)

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Article Cardiac & Cardiovascular Systems

Impact of estimated left atrial volume on prognosis in patients with asymptomatic mild to moderate aortic valve stenosis

Maria-Angela Losi et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2019)

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Article Clinical Neurology

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

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LANCET NEUROLOGY (2019)

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Article Transplantation

Long-term blood pressure monitoring by office and 24-h ambulatory blood pressure in renal transplant patients: a longitudinal study

Francesca Mallamaci et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2019)

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Article Medicine, General & Internal

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

S. D. Wiviott et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Article Medicine, General & Internal

Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

Deepak L. Bhatt et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

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Review Peripheral Vascular Disease

Effects of mineralocorticoid receptor antagonists in proteinuric kidney disease: a systematic review and meta-analysis of randomized controlled trials

Maria-Eleni Alexandrou et al.

JOURNAL OF HYPERTENSION (2019)

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Article Public, Environmental & Occupational Health

Association between lifestyle risk factors and incident hypertension among middle-aged and older Australians

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PREVENTIVE MEDICINE (2019)

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Review Cardiac & Cardiovascular Systems

Blood Pressure Management in Afferent Baroreflex Failure JACC Review Topic of the Week

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

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Review Clinical Neurology

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

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STROKE (2019)

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Review Peripheral Vascular Disease

Schedules for Self-monitoring Blood Pressure: A Systematic Review

James A. Hodgkinson et al.

AMERICAN JOURNAL OF HYPERTENSION (2019)

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Article Urology & Nephrology

Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial

Luis M. Ruilope et al.

AMERICAN JOURNAL OF NEPHROLOGY (2019)

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Review Peripheral Vascular Disease

Three Generations of β-blockers: History, Class Differences and Clinical Applicability

Gabriel T. do Vale et al.

CURRENT HYPERTENSION REVIEWS (2019)

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Letter Cardiac & Cardiovascular Systems

Blood pressure management in patients with symptomatic peripheral artery disease: insights from the PORTRAIT registry

Lina Ya'qoub et al.

EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES (2019)

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Article Cardiac & Cardiovascular Systems

Sex-Based Differences in Heart Failure Across the Ejection Fraction Spectrum Phenotyping, and Prognostic and Therapeutic Implications

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JACC-HEART FAILURE (2019)

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Review Psychiatry

The association between PTSD and cardiovascular disease and its risk factors in male veterans of the Iraq/Afghanistan conflicts: a systematic review

Daniel Dyball et al.

INTERNATIONAL REVIEW OF PSYCHIATRY (2019)

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Article Medicine, General & Internal

Immediate Antihypertensive Treatment for Patients With Acute Ischemic Stroke With or Without History of Hypertension A Secondary Analysis of the CATIS Randomized Clinical Trial

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JAMA NETWORK OPEN (2019)

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Article Urology & Nephrology

Efficacy and Safety of Sodium Zirconium Cyclosilicate for Treatment of Hyperkalemia: An 11-Month Open-Label Extension of HARMONIZE

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AMERICAN JOURNAL OF NEPHROLOGY (2019)

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Article Cardiac & Cardiovascular Systems

ESC Council on hypertension position document on themanagement of hypertensive emergencies

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EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2019)

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Review Immunology

Immune mechanisms of hypertension

Grant R. Drummond et al.

NATURE REVIEWS IMMUNOLOGY (2019)

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Review Cardiac & Cardiovascular Systems

Gender Differences in Atrial Fibrillation: A Review of Epidemiology, Management, and Outcomes

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CURRENT CARDIOLOGY REVIEWS (2019)

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Article Cardiac & Cardiovascular Systems

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC)

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Article Cardiac & Cardiovascular Systems

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)

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EUROPEAN HEART JOURNAL (2018)

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Article Peripheral Vascular Disease

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

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HYPERTENSION (2018)

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Review Immunology

The immunology of hypertension

Allison E. Norlander et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2018)

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Article Geriatrics & Gerontology

Lower blood pressure during antihypertensive treatment is associated with higher all-cause mortality and accelerated cognitive decline in the oldest-old. Data from the Leiden 85-plus Study

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AGE AND AGEING (2018)

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Article Cardiac & Cardiovascular Systems

Sex Differences of Patients With Systemic Hypertension (From the Analysis of the Systolic Blood Pressure Intervention Trial [SPRINT])

Roberto Ochoa-Jimenez et al.

AMERICAN JOURNAL OF CARDIOLOGY (2018)

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Article Peripheral Vascular Disease

A Comparison of the Diagnostic Accuracy of Common Office Blood Pressure Measurement Protocols

Ian M. Kronish et al.

AMERICAN JOURNAL OF HYPERTENSION (2018)

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Article Obstetrics & Gynecology

Is there benefit o con inue magnesium sulphate postpartum in women receiving magnesium sulphate before delivery? A randomised controlled study

P. Vigil-DeGracia et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2018)

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Review Obstetrics & Gynecology

Recurrence of pre-eclampsia and the risk of future hypertension and cardiovascular disease: a systematic review and meta-analysis

L. Brouwers et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2018)

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Article Peripheral Vascular Disease

Evidence-based proposal for the number of ambulatory readings required for assessing blood pressure level in research settings: an analysis of the IDACO database

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BLOOD PRESSURE (2018)

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Article Primary Health Care

Hypertension referrals from community pharmacy to general practice: multivariate logistic regression analysis of 131 419 patients

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BRITISH JOURNAL OF GENERAL PRACTICE (2018)

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Review Endocrinology & Metabolism

An Update on Hypertension in Children With Type 1 Diabetes

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CANADIAN JOURNAL OF DIABETES (2018)

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Review Critical Care Medicine

Noninvasive BP Monitoring in the Critically Ill Time to Abandon the Arterial Catheter?

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CHEST (2018)

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Article Cardiac & Cardiovascular Systems

Association of Blood Pressure Measurements With Peripheral Artery Disease Events: Reanalysis of the ALLHAT Data

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CIRCULATION (2018)

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Review Medical Laboratory Technology

Uric acid and cardiovascular disease

Gjin Ndrepepa

CLINICA CHIMICA ACTA (2018)

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Article Clinical Neurology

Consensus statement on the definition of neurogenic supine hypertension in cardiovascular autonomic failure by the American Autonomic Society (AAS) and the European Federation of Autonomic Societies (EFAS)

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CLINICAL AUTONOMIC RESEARCH (2018)

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Review Endocrinology & Metabolism

Diagnostic approach to low-renin hypertension

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CLINICAL ENDOCRINOLOGY (2018)

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Article Urology & Nephrology

Central Blood Pressure and Cardiovascular Outcomes in Chronic Kidney Disease

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CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult

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CLINICAL RESEARCH IN CARDIOLOGY (2018)

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Review Peripheral Vascular Disease

Institutional Pathways to Improve Care of Patients with Elevated Blood Pressure in the Emergency Department

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CURRENT HYPERTENSION REPORTS (2018)

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Review Peripheral Vascular Disease

Resistant Hypertension: Time to Consider the Best Fifth Anti-Hypertensive Treatment

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CURRENT HYPERTENSION REPORTS (2018)

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Review Endocrinology & Metabolism

Blood pressure targets in type 2 diabetes. Evidence against or in favour of an aggressive approach

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DIABETOLOGIA (2018)

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Review Environmental Sciences

Global association between ambient air pollution and blood pressure: A systematic review and meta-analysis

Bo-Yi Yang et al.

ENVIRONMENTAL POLLUTION (2018)

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Article Cardiac & Cardiovascular Systems

Clinical recommendations for high altitude exposure of individuals with pre-existing cardiovascular conditions

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EUROPEAN HEART JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120-140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

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EUROPEAN HEART JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Early cardiovascular protection by initial two-drug fixed-dose combination treatment vs. monotherapy in hypertension

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EUROPEAN HEART JOURNAL (2018)

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Article Peripheral Vascular Disease

Prognostic Value of Echocardiography in Hypertensive Versus Nonhypertensive Participants From the General Population

Daniel Modin et al.

HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Atrial Fibrillation Detection During 24-Hour Ambulatory Blood Pressure Monitoring: Comparison With 24-Hour Electrocardiography

Anastasios Kollias et al.

HYPERTENSION (2018)

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Review Peripheral Vascular Disease

Natriuretic Peptides in Cardiovascular and Metabolic Crosstalk: Implications for Hypertension Management

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HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Refractory Hypertension Is not Attributable to Intravascular Fluid Retention as Determined by Intracardiac Volumes

Alejandro Velasco et al.

HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Sympathetic Nerve Traffic Activation in Essential Hypertension and Its Correlates: Systematic Reviews and Meta-Analyses

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HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Blood Pressure Measurement in SPRINT (Systolic Blood Pressure Intervention Trial)

Karen C. Johnson et al.

HYPERTENSION (2018)

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Article Cardiac & Cardiovascular Systems

Spironolactone versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension - The ReHOT Randomized Study (Resistant Hypertension Optimal Treatment)

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JOURNAL FUR HYPERTONIE (2018)

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Article Peripheral Vascular Disease

Pulse Wave Velocity Predicts the Progression of Blood Pressure and Development of Hypertension in Young Adults

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HYPERTENSION (2018)

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Review Allergy

Obesity and asthma

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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

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Article Peripheral Vascular Disease

Association between encounter frequency and time to blood pressure control among patients with newly diagnosed hypertension: a retrospective cohort study

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JOURNAL OF CLINICAL HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Blood pressure measurement in special populations and circumstances

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JOURNAL OF CLINICAL HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Validation protocols for blood pressure measuring devices in the 21st century

George S. Stergiou et al.

JOURNAL OF CLINICAL HYPERTENSION (2018)

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Article Ophthalmology

New Recommendations for the Treatment of Systemic Hypertension and their Potential Implications for Glaucoma Management

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JOURNAL OF GLAUCOMA (2018)

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Review Peripheral Vascular Disease

Effects of blood pressure-lowering treatment on cardiovascular outcomes andmortality: 13-benefits and adverse events in older and younger patients with hypertension: overview, meta-analyses and meta-regression analyses of randomized trials

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JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Risk of new-onset metabolic syndrome associated with white-coat and masked hypertension: data from a general population

Cesare Cuspidi et al.

JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Clinical characteristics and risk of hypertension needing treatment in young patients with systolic hypertension identified with ambulatory monitoring

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JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Comparison between invasive and noninvasive techniques of evaluation of microvascular structural alterations

Carolina De Ciuceis et al.

JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Blood pressure in acute ischemic stroke: challenges in trial interpretation and clinical management: position of the ESH Working Group on Hypertension and the Brain

Dariusz Gasecki et al.

JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

A universal standard for the validation of blood pressure measuring devices: Association for the Advancement of Medical Instrumentation/European Society of Hypertension/International Organization for Standardization (AAMI/ESH/ISO) Collaboration Statement

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JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Gender, blood pressure, and cardiovascular and renal outcomes in adults with hypertension from the Systolic Blood Pressure Intervention Trial

Capri G. Foy et al.

JOURNAL OF HYPERTENSION (2018)

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Article Peripheral Vascular Disease

Isolated systolic hypertension in the young: a position paper endorsed by the European Society of Hypertension

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JOURNAL OF HYPERTENSION (2018)

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Article Dermatology

Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark

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JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2018)

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Review Cardiac & Cardiovascular Systems

Angiotensin-Converting Enzyme Inhibitors in Hypertension To Use or Not to Use?

Franz H. Messerli et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Urology & Nephrology

Pooled analysis of Phase III trials indicate contrasting influences of renal function on blood pressure, body weight, and HbA1c reductions with empagliflozin

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KIDNEY INTERNATIONAL (2018)

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Review Medicine, General & Internal

Cardiovascular, respiratory, and related disorders: key messages from Disease Control Priorities, 3rd edition

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Article Medicine, General & Internal

Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals

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LANCET (2018)

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Article Medicine, General & Internal

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial

David E. Kandzari et al.

LANCET (2018)

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Article Medicine, General & Internal

Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial

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LANCET (2018)

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Review Medicine, General & Internal

Clinical inertia in the pharmacological management of hypertension A systematic review and meta-analysis

Tal Milman et al.

MEDICINE (2018)

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Article Medicine, General & Internal

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout

William B. White et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

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Article Ophthalmology

Systemic Medication Associations with Presumed Advanced or Uncontrolled Primary Open-Angle Glaucoma

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OPHTHALMOLOGY (2018)

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Article Ophthalmology

Glaucomatous Optic Neuropathy Associated with Nocturnal Dip in Blood Pressure

Jesus D. Melgarejo et al.

OPHTHALMOLOGY (2018)

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Review Pharmacology & Pharmacy

Atrial fibrillation and arterial hypertension

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PHARMACOLOGICAL RESEARCH (2018)

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Review Pharmacology & Pharmacy

Long-Term Beta-Blocker Therapy after Myocardial Infarction in the Reperfusion Era: A Systematic Review

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PHARMACOTHERAPY (2018)

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Article Endocrinology & Metabolism

Hookah smoking is strongly associated with diabetes mellitus, metabolic syndrome and obesity: a population-based study

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DIABETOLOGY & METABOLIC SYNDROME (2018)

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Article Multidisciplinary Sciences

Uncontrolled hypertension increases risk of all-cause and cardiovascular disease mortality in US adults: the NHANES III Linked Mortality Study

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SCIENTIFIC REPORTS (2018)

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Review Medicine, General & Internal

Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

Bryant R. England et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Isolated systolic hypertension of the young and its association with central blood pressure in a large multi-ethnic population. The HELIUS study

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EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2018)

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Review Cardiac & Cardiovascular Systems

Association between progestin-only contraceptive use and cardiometabolic outcomes: A systematic review and meta-analysis

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EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2018)

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Review Medicine, General & Internal

Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications

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BMJ-BRITISH MEDICAL JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle-Aged Adults

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JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

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Review Cardiac & Cardiovascular Systems

Sex-Specific Associations Between Alcohol Consumption and Incidence of Hypertension: A Systematic Review and Meta-Analysis of Cohort Studies

Michael Roerecke et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

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Review Medicine, General & Internal

Association of Blood Pressure Lowering With Mortality and Cardiovascular Disease Across Blood Pressure Levels A Systematic Review and Meta-analysis

Mattias Brunstrom et al.

JAMA INTERNAL MEDICINE (2018)

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Article Endocrinology & Metabolism

Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

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LANCET DIABETES & ENDOCRINOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction The TOPCAT Trial

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JACC-HEART FAILURE (2018)

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Review Obstetrics & Gynecology

The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice

Mark A. Brown et al.

PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH (2018)

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Article Medicine, General & Internal

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NATURE REVIEWS DISEASE PRIMERS (2018)

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Article Cardiac & Cardiovascular Systems

Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study

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ATHEROSCLEROSIS (2018)

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Article Cardiac & Cardiovascular Systems

Genetic Predisposition to High Blood Pressure and Lifestyle Factors Associations With Midlife Blood Pressure Levels and Cardiovascular Events

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CIRCULATION (2018)

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Article Cardiac & Cardiovascular Systems

Empagliflozin and Clinical Outcomes in Patients With Type 2 Diabetes Mellitus, Established Cardiovascular Disease, and Chronic Kidney Disease

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CIRCULATION (2018)

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Article Cardiac & Cardiovascular Systems

Recommendations for participation in competitive sports of athletes with arterial hypertension: a position statement from the sports cardiology section of the European Association of Preventive Cardiology (EAPC)

Josef Niebauer et al.

EUROPEAN HEART JOURNAL (2018)

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Article Cardiac & Cardiovascular Systems

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Vera Regitz-Zagrosek et al.

EUROPEAN HEART JOURNAL (2018)

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Article Geriatrics & Gerontology

Atrial fibrillation and medication treatment among centenarians: Are all very old patients treated the same?

Reinhold Kreutz et al.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2018)

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Article Health Care Sciences & Services

Interventions to support shared decision making for hypertension: A systematic review of controlled studies

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HEALTH EXPECTATIONS (2018)

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Article Peripheral Vascular Disease

Initial Antihypertensive Treatment Strategies and Therapeutic Inertia: Evidence From a Large Population-Based Cohort

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HYPERTENSION (2018)

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Review Peripheral Vascular Disease

Prognostic Value of Masked Uncontrolled Hypertension: Systematic Review and Meta-Analysis

Sante D. Pierdomenico et al.

HYPERTENSION (2018)

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Article Medicine, General & Internal

Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka A Randomized Clinical Trial

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

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Article Cardiac & Cardiovascular Systems

Ideal Blood Pressure in Patients With Atrial Fibrillation

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Losartan Versus Atenolol for Prevention of Aortic Dilation in Patients With Marfan Syndrome

Gisela Teixido-Tura et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

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Article Cardiac & Cardiovascular Systems

Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT

Srinivasan Beddhu et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)

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Article Cardiac & Cardiovascular Systems

Association of sodium intake and major cardiovascular outcomes: a dose-response meta-analysis of prospective cohort studies

Yaobin Zhu et al.

BMC CARDIOVASCULAR DISORDERS (2018)

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Review Pharmacology & Pharmacy

Sodium Zirconium Cyclosilicate: A Review in Hyperkalaemia

Sheridan M. Hoy

DRUGS (2018)

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Article Peripheral Vascular Disease

Improving Hypertension Control in Primary Care With the Measure Accurately, Act Rapidly, and Partner With Patients Protocol: Results at 6 and 12 Months

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HYPERTENSION (2018)

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Cost-Utility of an Objective Biochemical Measure to Improve Adherence to Antihypertensive Treatment

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Editorial Material Medicine, General & Internal

High Blood Pressure in Young Adulthood and Risk of Premature Cardiovascular Disease Calibrating Treatment Benefits to Potential Harm

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

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Article Medicine, General & Internal

Association of Blood Pressure Classification in Korean Young Adults According to the 2017 American College of Cardiology/American Heart Association Guidelines With Subsequent Cardiovascular Disease Events

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Article Medicine, General & Internal

Association of Blood Pressure Classification in Young Adults Using the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline With Cardiovascular Events Later in Life

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Review Peripheral Vascular Disease

Renal resistive index in hypertensive patients

Ioannis Andrikou et al.

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Office blood pressure measurement types: Different methodology-Different clinical conclusions

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Article Peripheral Vascular Disease

2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology andthe European Society of Hypertension ESC/ESH Task Force for the Management of Arterial Hypertension

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Article Medicine, General & Internal

Sex differences in risk factors for myocardial infarction: cohort study of UK Biobank participants

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Machine learning of big data in gaining insight into successful treatment of hypertension

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Self-reported Medication Adherence and CKD Progression

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Review Peripheral Vascular Disease

Hypertension and Organ Damage in Women

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Review Pharmacology & Pharmacy

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Regular aerobic exercise and blood pressure in East Asians: A meta-analysis of randomized controlled trials

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Article Peripheral Vascular Disease

Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension: The ReHOT Randomized Study (Resistant Hypertension Optimal Treatment)

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Review Rheumatology

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Use of oscillometric devices in atrial fibrillation: a comparison of three devices and invasive blood pressure measurement

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Screening for Atrial Fibrillation During Automatic Blood Pressure Measurements

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IEEE JOURNAL OF TRANSLATIONAL ENGINEERING IN HEALTH AND MEDICINE (2018)

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Article Medicine, General & Internal

Long-term Outcomes of the Effects of Home Blood Pressure Telemonitoring and Pharmacist Management on Blood Pressure Among Adults With Uncontrolled Hypertension Follow-up of a Cluster Randomized Clinical Trial

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JAMA NETWORK OPEN (2018)

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Improved Insulin Sensitivity With Angiotensin Receptor Neprilysin Inhibition in Individuals With Obesity and Hypertension

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CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)

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Article Peripheral Vascular Disease

Antihypertensive Medication Postpones the Onset of Glaucoma Evidence From a Nationwide Study

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Article Peripheral Vascular Disease

Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network

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Blood Pressure Reduction and Secondary Stroke Prevention: A Systematic Review and Metaregression Analysis of Randomized Clinical Trials

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Article Peripheral Vascular Disease

Risk of hypertensive disorders in pregnancy following assisted reproductive technology: overview and meta-analysis

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Article Cardiac & Cardiovascular Systems

Office blood pressure or ambulatory blood pressure for the prediction of cardiovascular events

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EUROPEAN HEART JOURNAL (2017)

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Article Cardiac & Cardiovascular Systems

Validation of non-invasive central blood pressure devices: ARTERY Society task force consensus statement on protocol standardization

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EUROPEAN HEART JOURNAL (2017)

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Article Cardiac & Cardiovascular Systems

Proceedings from the 2nd European Clinical Consensus Conference for device-based therapies for hypertension: state of the art and considerations for the future

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Article Health Care Sciences & Services

Spot protein-creatinine ratio and spot albumin-creatinine ratio in the assessment of pre-eclampsia: a diagnostic accuracy study with decision-analytic model-based economic evaluation and acceptability analysis

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Article Peripheral Vascular Disease

Relative and Combined Prognostic Importance of On-Treatment Mean and Visit-to-Visit Blood Pressure Variability in ONTARGET and TRANSCEND Patients

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Article Peripheral Vascular Disease

Office Pulse Pressure Is a Predictor of Favorable Outcome in Young-to Middle-Aged Subjects With Stage 1 Hypertension

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Article Peripheral Vascular Disease

Pregnancy Outcome After First Trimester Use of Methyldopa A Prospective Cohort Study

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Brachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease An Individual Participant Data Meta-Analysis

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Article Peripheral Vascular Disease

Biochemical Screening for Nonadherence Is Associated With Blood Pressure Reduction and Improvement in Adherence

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Article Peripheral Vascular Disease

Dose-Response Association Between Physical Activity and Incident Hypertension A Systematic Review and Meta-Analysis of Cohort Studies

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Article Peripheral Vascular Disease

Cardiovascular Risk Associated With White-Coat Hypertension Con Side of the Argument

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Article Peripheral Vascular Disease

Prevalence, Treatment, and Control Rates of Conventional and Ambulatory Hypertension Across 10 Populations in 3 Continents

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Article Peripheral Vascular Disease

Risk Factors for Nonadherence to Antihypertensive Treatment

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Article Medicine, General & Internal

Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery A Randomized Clinical Trial

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

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Article Endocrinology & Metabolism

Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline

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Article Peripheral Vascular Disease

The importance of frequent return visits and hypertension control among US young adults: a multidisciplinary group practice observational study

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Review Peripheral Vascular Disease

Effectiveness of home blood pressure telemonitoring: a systematic review and meta-analysis of randomised controlled studies

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Review Peripheral Vascular Disease

Meditation and blood pressure: ameta-analysis of randomized clinical trials

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Review Peripheral Vascular Disease

White-coat hypertension is a risk factor for cardiovascular diseases and totalmortality

Yuli Huang et al.

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Review Peripheral Vascular Disease

Effects of blood-pressure-lowering treatment on outcome incidence in hypertension: 10-Should blood pressure management differ in hypertensive patients with and without diabetes mellitus? Overview and meta-analyses of randomized trials

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Article Peripheral Vascular Disease

Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH)

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Article Peripheral Vascular Disease

Increased incidence of open-angle glaucoma among hypertensive patients: an11-year nationwide retrospective cohort study

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Association between exposure to noise and risk of hypertension: a meta-analysis of observational epidemiological studies

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Review Peripheral Vascular Disease

Effects of blood-pressure-lowering treatment on outcome incidence. 12. Effects in individuals with high-normal and normal blood pressure: overview andmeta-analyses of randomized trials

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Review Peripheral Vascular Disease

Withdrawal of antihypertensive medication: a systematic review

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Lower dementia risk with different classes of antihypertensive medication in older patients

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The polypill in cardiovascular prevention: evidence, limitations and perspective - position paper of the European Society of Hypertension

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Review Peripheral Vascular Disease

Associations of rotational shift work and night shift status with hypertension: a systematic review and meta-analysis

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Article Peripheral Vascular Disease

Noninvasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: a consensus article from the European Association of Cardiovascular Imaging, the European Society of Cardiology Council on Hypertension and the European Society of Hypertension

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Review Peripheral Vascular Disease

Association of night-time home blood pressure with night-time ambulatory blood pressure and target-organ damage: a systematic review and meta-analysis

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Review Peripheral Vascular Disease

Sources of inaccuracy in themeasurement of adult patients' resting blood pressure in clinical settings: a systematic review

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Ocular fundus photography with a smartphone device in acute hypertension

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Hydrochlorothiazide use is strongly associated with risk of lip cancer

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Relationship of Alcohol Consumption to All-Cause, Cardiovascular, and Cancer-Related Mortality in US Adults

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Achieving the BpTRUth: emergency department hypertension screening and the Centers for Medicare & Medicaid Services quality measure

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Effects of Intensive BP Control in CKD

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Speculations on salt and the genesis of arterial hypertension

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Acute change in glomerular filtration rate with inhibition of the renin-angiotensin system does not predict subsequent renal and cardiovascular outcomes

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Endovascular baroreflex amplification for resistant hypertension: a safety and proof-of-principle clinical study

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Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

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Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review

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Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia

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Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

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Article Medicine, General & Internal

Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study

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Time in Therapeutic Range, as a Determinant of All-Cause Mortality in Patients With Hypertension

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Left Ventricular Hypertrophy Regression During Antihypertensive Treatment in an Outpatient Clinic (the Campania Salute Network)

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Review Cardiac & Cardiovascular Systems

Effects of Sodium-Glucose Cotransporter 2 Inhibitors on 24-Hour Ambulatory Blood Pressure: A Systematic Review and Meta-Analysis

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Association of Intensive Blood Pressure Control and Kidney Disease Progression in Nondiabetic Patients With Chronic Kidney Disease A Systematic Review and Meta-analysis

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Article Medicine, General & Internal

Association of Changes in Neighborhood-Level Racial Residential Segregation With Changes in Blood Pressure Among Black Adults The CARDIA Study

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Review Medicine, General & Internal

Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5 A Systematic Review and Meta-analysis

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Association of Systemic Medication Use With Intraocular Pressure in a Multiethnic Asian Population The Singapore Epidemiology of Eye Diseases Study

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Management of Blood Pressure in Patients with Glaucoma

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Review Respiratory System

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Gut microbiota dysbiosis contributes to the development of hypertension

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Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials

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Reference values of brachial-ankle pulse wave velocity according to age and blood pressure in a central Asia population

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Effects of calcium channel blockers comparing to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in patients with hypertension and chronic kidney disease stage 3 to 5 and dialysis: A systematic review and meta-analysis

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Thirty Years of Evidence on the Efficacy of Drug Treatments for Chronic Heart Failure With Reduced Ejection Fraction A Network Meta-Analysis

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Malignant Hypertension Revisited-Does This Still Exist?

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Review Peripheral Vascular Disease

Renal Artery Stenosis in Patients with Resistant Hypertension: Stent It or Not?

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No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial

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Review Cardiac & Cardiovascular Systems

Cardiovascular outcomes at different on-treatment blood pressures in the hypertensive patients of the VALUE trial

Giuseppe Mancia et al.

EUROPEAN HEART JOURNAL (2016)

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Article Peripheral Vascular Disease

Association of Central Versus Brachial Blood Pressure With Target-Organ Damage Systematic Review and Meta-Analysis

Anastasios Kollias et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Achieved Blood Pressure and Outcomes in the Secondary Prevention of Small Subcortical Strokes Trial

Michelle C. Odden et al.

HYPERTENSION (2016)

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Article Health Care Sciences & Services

Triamterene Enhances the Blood Pressure Lowering Effect of Hydrochlorothiazide in Patients with Hypertension

Wanzhu Tu et al.

JOURNAL OF GENERAL INTERNAL MEDICINE (2016)

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Review Medicine, General & Internal

Isolated Systolic Hypertension: An Update After SPRINT

Chirag Bavishi et al.

AMERICAN JOURNAL OF MEDICINE (2016)

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Review Obstetrics & Gynecology

Exercise during pregnancy in normal-weight women and risk of preterm birth: a systematic review and meta-analysis of randomized controlled trials

Daniele Di Mascio et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2016)

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Article Obstetrics & Gynecology

Exercise during pregnancy protects against hypertension and macrosomia: randomized clinical trial

Ruben Barakat et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2016)

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Letter Anesthesiology

The measurement of adult blood pressure and management of hypertension before elective surgery: Joint Guidelines from the Association of Anaesthetists of Great Britain and Ireland and the British Hypertension Society

A. Hartle et al.

ANAESTHESIA (2016)

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Article Endocrinology & Metabolism

Primary aldosteronism and pregnancy

Ester Landau et al.

ANNALES D ENDOCRINOLOGIE (2016)

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Review Medicine, General & Internal

Pharmacist-Led Chronic Disease Management: A Systematic Review of Effectiveness and Harms Compared With Usual Care

Nancy Greer et al.

ANNALS OF INTERNAL MEDICINE (2016)

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Article Surgery

Cardiovascular risk prevention and all-cause mortality in primary care patients with an abdominal aortic aneurysm

S. S. Bahia et al.

BRITISH JOURNAL OF SURGERY (2016)

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Article Cardiac & Cardiovascular Systems

Assessing Optimal Blood Pressure in Patients With Asymptomatic Aortic Valve Stenosis The Simvastatin Ezetimibe in Aortic Stenosis Study (SEAS)

Olav W. Nielsen et al.

CIRCULATION (2016)

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Review Pharmacology & Pharmacy

Blood pressure effects of CPAP in nonresistant and resistant hypertension associated with OSA: A systematic review of randomized clinical trials

Carlos A. Feldstein

CLINICAL AND EXPERIMENTAL HYPERTENSION (2016)

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Article Urology & Nephrology

Masked Hypertension and Elevated Nighttime Blood Pressure in CKD: Prevalence and Association with Target Organ Damage

Paul E. Drawz et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)

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Article Obstetrics & Gynecology

Impact of estrogen type on cardiovascular safety of combined oral contraceptives

Juergen Dinger et al.

CONTRACEPTION (2016)

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Review Oncology

Incidence and relative risk of adverse events of special interest in patients with castration resistant prostate cancer treated with CYP-17 inhibitors: A meta-analysis of published trials

Giandomenico Roviello et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2016)

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Review Peripheral Vascular Disease

Asking the Patient or Measuring Blood Pressure in the Emergency Department: Which One is Best?

Per H. Skoglund et al.

CURRENT HYPERTENSION REPORTS (2016)

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Review Peripheral Vascular Disease

How to Screen for Non-Adherence to Antihypertensive Therapy

Pankaj Gupta et al.

CURRENT HYPERTENSION REPORTS (2016)

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Article Endocrinology & Metabolism

Association Between High and Very High Albuminuria and Nighttime Blood Pressure: Influence of Diabetes and Chronic Kidney Disease

Gema Ruiz-Hurtado et al.

DIABETES CARE (2016)

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Article Cardiac & Cardiovascular Systems

2016 European Guidelines on cardiovascular disease prevention in clinical practice

Massimo F. Piepoli et al.

EUROPEAN HEART JOURNAL (2016)

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Article Peripheral Vascular Disease

Modest Salt Reduction Lowers Blood Pressure and Albumin Excretion in Impaired Glucose Tolerance and Type 2 Diabetes Mellitus A Randomized Double-Blind Trial

Rebecca J. Suckling et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Comparative Cost-Effectiveness of Conservative or Intensive Blood Pressure Treatment Guidelines in Adults Aged 35-74 Years The Cardiovascular Disease Policy Model

Nathalie Moise et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Impact of Empagliflozin on Blood Pressure in Patients With Type 2 Diabetes Mellitus and Hypertension by Background Antihypertensive Medication

Giuseppe Mancia et al.

HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Will Exercise Advice Be Sufficient for Treatment of Young Adults With Prehypertension and Hypertension? A Systematic Review and Meta-Analysis

Wilby Williamson et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Ethnic Differences in and Childhood Influences on Early Adult Pulse Wave Velocity The Determinants of Adolescent, Now Young Adult, Social Wellbeing, and Health Longitudinal Study

J. Kennedy Cruickshank et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

An Expert Opinion From the European Society of Hypertension-European Union Geriatric Medicine Society Working Group on the Management of Hypertension in Very Old, Frail Subjects

Athanase Benetos et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Effects of Different Dietary Interventions on Blood Pressure Systematic Review and Meta-Analysis of Randomized Controlled Trials

Hawkins C. Gay et al.

HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Unattended Blood Pressure Measurements in the Systolic Blood Pressure Intervention Trial Implications for Entry and Achieved Blood Pressure Values Compared With Other Trials

Sverre E. Kjeldsen et al.

HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Evaluation of Adherence Should Become an Integral Part of Assessment of Patients With Apparently Treatment-Resistant Hypertension

Elena Berra et al.

HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Prognostic Effect of the Nocturnal Blood Pressure Fall in Hypertensive Patients The Ambulatory Blood Pressure Collaboration in Patients With Hypertension (ABC-H) Meta-Analysis

Gil F. Salles et al.

HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Research Needs to Improve Hypertension Treatment and Control in African Americans

Paul K. Whelton et al.

HYPERTENSION (2016)

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Review Medicine, General & Internal

Systematic review: antihypertensive drug therapy in patients of African and South Asian ethnicity

Lizzy M. Brewster et al.

INTERNAL AND EMERGENCY MEDICINE (2016)

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Review Cardiac & Cardiovascular Systems

Screening for atrial fibrillation with automated blood pressure measurement: Research evidence and practice recommendations

Willem J. Verberk et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2016)

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Review Medicine, General & Internal

Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions A Systematic Review and Meta-analysis

Michael G. Silverman et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

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Article Medicine, General & Internal

Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years A Randomized Clinical Trial

Jeff D. Williamson et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2016)

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Article Peripheral Vascular Disease

Nocturnal Hypertension and Subclinical Cardiac and Carotid Damage: An Updated Review and Meta-Analysis of Echocardiographic Studies

Cesare Cuspidi et al.

JOURNAL OF CLINICAL HYPERTENSION (2016)

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Editorial Material Peripheral Vascular Disease

A Short History of Automated Office Blood Pressure-15 Years to SPRINT

Martin G. Myers

JOURNAL OF CLINICAL HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Adverse effect of diabetes and hyperglycaemia on arterial stiffness in Europeans, South Asians, and African Caribbeans in the SABRE study

Chloe M. Park et al.

JOURNAL OF HYPERTENSION (2016)

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Editorial Material Peripheral Vascular Disease

A useful tool to improve the case detection rate of primary aldosteronism: the aldosterone-renin ratio (ARR)-App

Gian Paolo Rossi et al.

JOURNAL OF HYPERTENSION (2016)

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Editorial Material Peripheral Vascular Disease

Can we predict outcome by noninvasive assessment of renal haemodynamics in hypertension? The role of renal resistive index

Francesca Viazzi et al.

JOURNAL OF HYPERTENSION (2016)

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Review Peripheral Vascular Disease

White-coat hypertension and cardiovascular events: ameta-analysis

Alexandros Briasoulis et al.

JOURNAL OF HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Effects of blood pressure lowering on outcome incidence in hypertension: 7. Effects of more vs. less intensive blood pressure lowering and different achieved blood pressure levels - updated overview and meta-analyses of randomized trials

Costas Thomopoulos et al.

JOURNAL OF HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Risks associated with permanent discontinuation of blood pressure-lowering medications in patients with type 2 diabetes

Yoichiro Hirakawa et al.

JOURNAL OF HYPERTENSION (2016)

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Review Peripheral Vascular Disease

Digital interventions to promote self-management in adults with hypertension systematic review andmeta-analysis

Gary McLean et al.

JOURNAL OF HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Interrupting prolonged sitting with brief bouts of light walking or simple resistance activities reduces resting blood pressure and plasma noradrenaline in type 2 diabetes

Paddy C. Dempsey et al.

JOURNAL OF HYPERTENSION (2016)

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Article Peripheral Vascular Disease

2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents

Empar Lurbe et al.

JOURNAL OF HYPERTENSION (2016)

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Article Peripheral Vascular Disease

Copeptin is increased in resistant hypertension

Margarida Mendes et al.

JOURNAL OF HYPERTENSION (2016)

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Article Cardiac & Cardiovascular Systems

Normal Values of Left Ventricular Mass Index Assessed by Transthoracic Three-Dimensional Echocardiography

Kei Mizukoshi et al.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2016)

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Review Peripheral Vascular Disease

Studies comparing ambulatory blood pressure and home blood pressure on cardiovascular disease and mortality outcomes: a systematic review

Daichi Shimbo et al.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2016)

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Article Medicine, General & Internal

Rate control in atrial fibrillation

Isabelle C. Van Gelder et al.

LANCET (2016)

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Article Medicine, General & Internal

Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies

Andrew Mente et al.

LANCET (2016)

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Review Medicine, General & Internal

Interpretation of the evidence for the efficacy and safety of statin therapy

Rory Collins et al.

LANCET (2016)

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Article Medicine, General & Internal

Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study

Emmanuelle Vidal-Petiot et al.

LANCET (2016)

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Article Medicine, General & Internal

Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis

Xinfang Xie et al.

LANCET (2016)

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Review Medicine, General & Internal

Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis

Dena Ettehad et al.

LANCET (2016)

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Article Medicine, General & Internal

Risks of Adverse Events Following Coprescription of Statins and Calcium Channel Blockers A Nationwide Population-Based Study

Yi-Chun Wang et al.

MEDICINE (2016)

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Review Medicine, General & Internal

Comparative Effectiveness of Blood Pressure-lowering Drugs in Patients who have Already Suffered From Stroke Traditional and Bayesian Network Meta-analysis of Randomized Trials

Wei-Ting Wang et al.

MEDICINE (2016)

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Article Biotechnology & Applied Microbiology

Ten years of anti-vascular endothelial growth factor therapy

Napoleone Ferrara et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

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Article Medicine, General & Internal

Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease

Eva M. Lonn et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Article Medicine, General & Internal

Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease

S. Yusuf et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Review Medicine, General & Internal

Cardiovascular Toxic Effects of Targeted Cancer Therapies

Javid J. Moslehi

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Article Medicine, General & Internal

Blood-Pressure and Cholesterol Lowering in Persons without Cardiovascular Disease

Salim Yusuf et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Article Medicine, General & Internal

Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage

Adnan I. Qureshi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Article Medicine, General & Internal

Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia

Harald Zeisler et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Review Endocrinology & Metabolism

Interventions that cause weight loss and the impact on cardiovascular risk factors: a systematic review and meta-analysis

E. Zomer et al.

OBESITY REVIEWS (2016)

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Article Multidisciplinary Sciences

Relationship between Blood Pressure and Outcomes in Acute Ischemic Stroke Patients Administered Lytic Medication in the TIMS-China Study

Wei Wu et al.

PLOS ONE (2016)

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Review Medicine, General & Internal

Hypertension in young adults

Toni De Venecia et al.

POSTGRADUATE MEDICINE (2016)

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Article Clinical Neurology

Blood Pressure and Risk of Vascular Dementia Evidence From a Primary Care Registry and a Cohort Study of Transient Ischemic Attack and Stroke

Connor A. Emdin et al.

STROKE (2016)

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Article Medicine, General & Internal

β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study

Etienne Puymirat et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Medicine, General & Internal

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

Emily Bartsch et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Medicine, General & Internal

Different systolic blood pressure targets for people with history of stroke or transient ischaemic attack: PAST-BP (Prevention After Stroke-Blood Pressure) randomised controlled trial

Jonathan Mant et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Review Medicine, General & Internal

Blood pressure variability and cardiovascular disease: systematic review and meta-analysis

Sarah L. Stevens et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Review Medicine, General & Internal

Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

Mattias Brunstrom et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Cardiac & Cardiovascular Systems

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

Sherif F. Nagueh et al.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2016)

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Review Cardiac & Cardiovascular Systems

The blood pressure-lowering effect of a single bout of resistance exercise: A systematic review and meta-analysis of randomised controlled trials

Juliano Casonatto et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2016)

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Article Medicine, General & Internal

β blockers and mortality after myocardial infarction in patients without heart failure: multicentre prospective cohort study

Etienne Puymirat et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Medicine, General & Internal

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

Emily Bartsch et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Medicine, General & Internal

Different systolic blood pressure targets for people with history of stroke or transient ischaemic attack: PAST-BP (Prevention After Stroke-Blood Pressure) randomised controlled trial

Jonathan Mant et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Review Medicine, General & Internal

Blood pressure variability and cardiovascular disease: systematic review and meta-analysis

Sarah L. Stevens et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Review Medicine, General & Internal

Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

Mattias Brunstrom et al.

BMJ-BRITISH MEDICAL JOURNAL (2016)

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Article Endocrinology & Metabolism

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

Morris J. Brown et al.

LANCET DIABETES & ENDOCRINOLOGY (2016)

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Review Multidisciplinary Sciences

Panethnic Differences in Blood Pressure in Europe: A Systematic Review and Meta-Analysis

Pietro Amedeo Modesti et al.

PLOS ONE (2016)

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Article Peripheral Vascular Disease

Screening for non-adherence to antihypertensive treatment as a part of the diagnostic pathway to renal denervation

P. Patel et al.

JOURNAL OF HUMAN HYPERTENSION (2016)

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Letter Ophthalmology

Estimating Mean Ocular Perfusion Pressure Using Mean Arterial Pressure and Intraocular Pressure

Karel Van Keer et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2016)

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Review Clinical Neurology

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

Heather M. Snyder et al.

ALZHEIMERS & DEMENTIA (2015)

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Review Public, Environmental & Occupational Health

The Contribution of Genomic Research to Explaining Racial Disparities in Cardiovascular Disease: A Systematic Review

Jay S. Kaufman et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2015)

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Review Peripheral Vascular Disease

The Effect of Self-Monitoring of Blood Pressure on Medication Adherence and Lifestyle Factors: A Systematic Review and Meta-Analysis

Benjamin R. Fletcher et al.

AMERICAN JOURNAL OF HYPERTENSION (2015)

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Review Medicine, General & Internal

Diagnostic and Predictive Accuracy of Blood Pressure Screening Methods With Consideration of Rescreening Intervals: A Systematic Review for the US Preventive Services Task Force

Margaret A. Piper et al.

ANNALS OF INTERNAL MEDICINE (2015)

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Review Medicine, General & Internal

Effects of Blood Pressure Reduction in Mild Hypertension A Systematic Review and Meta-analysis

Johan Sundstrom et al.

ANNALS OF INTERNAL MEDICINE (2015)

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Review Cardiac & Cardiovascular Systems

The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on peripheral circulation Endorsed by the Association for Research into Arterial Structure and Physiology (ARTERY) Society

Charalambos Vlachopoulos et al.

ATHEROSCLEROSIS (2015)

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Article Medicine, General & Internal

No evidence that frailty modifies the positive impact of antihypertensive treatment in very elderly people: an investigation of the impact of frailty upon treatment effect in the HYpertension in the Very Elderly Trial (HYVET) study, a double-blind, placebo-controlled study of antihypertensives in people with hypertension aged 80 and over

Jane Warwick et al.

BMC MEDICINE (2015)

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Article Cardiac & Cardiovascular Systems

A Systematic Review of Outcomes Following Percutaneous Transluminal Angioplasty and Stenting in the Treatment of Transplant Renal Artery Stenosis

A. T. Ngo et al.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Randomized Trial of the Effect of Pharmacist Prescribing on Improving Blood Pressure in the Community The Alberta Clinical Trial in Optimizing Hypertension (RxACTION)

Ross T. Tsuyuki et al.

CIRCULATION (2015)

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Article Cardiac & Cardiovascular Systems

The Epidemiology of Blood Pressure and Its Worldwide Management

Kazem Rahimi et al.

CIRCULATION RESEARCH (2015)

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Article Cardiac & Cardiovascular Systems

Randomized Controlled Trials of Blood Pressure Lowering in Hypertension A Critical Reappraisal

Alberto Zanchetti et al.

CIRCULATION RESEARCH (2015)

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Article Cardiac & Cardiovascular Systems

Clinical Value of Ambulatory Blood Pressure Evidence and Limits

Giuseppe Mancia et al.

CIRCULATION RESEARCH (2015)

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Article Urology & Nephrology

Rate of Change in Renal Function and Mortality in Elderly Treated Hypertensive Patients

Enayet K. Chowdhury et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)

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Review Oncology

Congestive heart failure with vascular endothelial growth factor receptor tyrosine kinase inhibitors

Pooja Ghatalia et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2015)

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Article Geriatrics & Gerontology

Antihypertensive Medications, Loop Diuretics, and Risk of Hip Fracture in the Elderly: A Population-Based Cohort Study of 81,617 Italian Patients Newly Treated Between 2005 and 2009

Giovanni Corrao et al.

DRUGS & AGING (2015)

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Article Cardiac & Cardiovascular Systems

Marfan Sartan: a randomized, double-blind, placebo-controlled trial

Olivier Milleron et al.

EUROPEAN HEART JOURNAL (2015)

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Review Pharmacology & Pharmacy

Advances in treatment of hyperkalemia in chronic kidney disease

Pantelis A. Sarafidis et al.

EXPERT OPINION ON PHARMACOTHERAPY (2015)

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Article Peripheral Vascular Disease

Head-to-Head Comparisons of Hydrochlorothiazide With Indapamide and Chlorthalidone Antihypertensive and Metabolic Effects

George C. Roush et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Refractory Hypertension Evidence of Heightened Sympathetic Activity as a Cause of Antihypertensive Treatment Failure

Tanja Dudenbostel et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Blood Pressure Responses to Renal Denervation Precede and Are Independent of the Sympathetic and Baroreflex Effects

Guido Grassi et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Adherence With Antihypertensive Drug Therapy and the Risk of Heart Failure in Clinical Practice

Giovanni Corrao et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Effects of Thiazide-Type and Thiazide-Like Diuretics on Cardiovascular Events and Mortality Systematic Review and Meta-Analysis

Rik H. G. Olde Engberink et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Lucas S. Aparicio et al.

HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Thresholds for Diagnosing Hypertension Based on Automated Office Blood Pressure Measurements and Cardiovascular Risk

Martin G. Myers et al.

HYPERTENSION (2015)

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Article Cardiac & Cardiovascular Systems

Long-term prognosis for individuals with hypertension undergoing coronary artery calcium scoring

Valentina Valenti et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2015)

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Article Medicine, General & Internal

Polypharmacy in the Aging Patient Management of Hypertension in Octogenarians

Athanase Benetos et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

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Article Medicine, General & Internal

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy A Randomized Clinical Trial

George L. Bakris et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

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Article Medicine, General & Internal

Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease The AMETHYST-DN Randomized Clinical Trial

George L. Bakris et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

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News Item Endocrinology & Metabolism

Lowering blood pressure in diabetes

Seema Kang

LANCET DIABETES & ENDOCRINOLOGY (2015)

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Article Peripheral Vascular Disease

The Role of Continuous Positive Airway Pressure in Blood Pressure Control for Patients With Obstructive Sleep Apnea and Hypertension: A Meta-Analysis of Randomized Controlled Trials

Xinyu Hu et al.

JOURNAL OF CLINICAL HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Blood pressure and renal function decline: a 7-year prospective cohort study in middle-aged rural Chinese men and women

Qin Wang et al.

JOURNAL OF HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Pressure-dependence of arterial stiffness: potential clinical implications

Bart Spronck et al.

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Review Peripheral Vascular Disease

Daily potassium intake and sodium-to-potassium ratio in the reduction of blood pressure: a meta-analysis of randomized controlled trials

Aristea Binia et al.

JOURNAL OF HYPERTENSION (2015)

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Article Peripheral Vascular Disease

The prognostic legacy of left ventricular hypertrophy: cumulative evidence after the MAVI study

Fabio Angeli et al.

JOURNAL OF HYPERTENSION (2015)

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Review Peripheral Vascular Disease

Effects of blood pressure-lowering on outcome incidence in hypertension: 5. Head-to-head comparisons of various classes of antihypertensive drugs - overview and meta-analyses

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JOURNAL OF HYPERTENSION (2015)

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Article Peripheral Vascular Disease

Effective risk stratification in patients with moderate cardiovascular risk using albuminuria and atherosclerotic plaques in the carotid arteries

Sara V. Greve et al.

JOURNAL OF HYPERTENSION (2015)

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Review Peripheral Vascular Disease

Sodium-glucose cotransporter-2 inhibitors and blood pressure decrease: a valuable effect of a novel antidiabetic class?

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Article Peripheral Vascular Disease

Roux-en-Y gastric bypass alleviates hypertension and is associated with an increase in mid-regional pro-atrial natriuretic peptide in morbid obese patients

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Article Peripheral Vascular Disease

Differential response of the natriuretic peptide system toweight loss and exercise in overweight or obese patients

Sven Haufe et al.

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Review Peripheral Vascular Disease

Diagnostic and therapeutic problems of isolated systolic hypertension

Giuseppe Mancia et al.

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Review Peripheral Vascular Disease

Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs - Overview and meta-analyses

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Article Rheumatology

Effect of Urate-lowering Therapy on the Risk of Cardiovascular Disease and All-cause Mortality in Patients with Gout: A Case-matched Cohort Study

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Article Cardiac & Cardiovascular Systems

Target Organ Complications and Cardiovascular Events Associated With Masked Hypertension and White-Coat Hypertension Analysis From the Dallas Heart Study

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Article Cardiac & Cardiovascular Systems

Isolated Systolic Hypertension in Young and Middle-Aged Adults and 31-Year Risk for Cardiovascular Mortality The Chicago Heart Association Detection Project in Industry Study

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Article Geriatrics & Gerontology

Do Arterial Hemodynamic Parameters Predict Cognitive Decline Over a Period of 2 Years in Individuals Older Than 80 Years Living in Nursing Homes? The PARTAGE Study

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Prevalence and trends of isolated systolic hypertension among untreated adults in the United States

Xuefeng Liu et al.

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A content analysis of smartphone-based applications for hypertension management

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Review Medicine, General & Internal

The double challenge of resistant hypertension and chronic kidney disease

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LANCET (2015)

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Article Medicine, General & Internal

Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial

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LANCET (2015)

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Article Medicine, General & Internal

Central arteriovenous anastomosis for the treatment of patients with uncontrolled hypertension (the ROX CONTROL HTN study): a randomised controlled trial

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LANCET (2015)

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Article Medicine, General & Internal

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

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Digital Health Interventions for the Prevention of Cardiovascular Disease: A Systematic Review and Meta-analysis

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MAYO CLINIC PROCEEDINGS (2015)

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Review Medicine, General & Internal

Blood Pressure Reduction in the Acute Phase of an Ischemic Stroke Does Not Improve Short- or Long-Term Dependency or Mortality A Meta-Analysis of Current Literature

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MEDICINE (2015)

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Article Medicine, General & Internal

Cardiovascular Events in Systemic Lupus Erythematosus A Nationwide Study in Spain From the RELESSER Registry

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MEDICINE (2015)

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Article Obstetrics & Gynecology

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Risks for mortality and renal replacement therapy in atherosclerotic renovascular disease compared with other causes of chronic kidney disease

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Less-Tight versus Tight Control of Hypertension in Pregnancy

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Cost-Effectiveness of Hypertension Therapy According to 2014 Guidelines

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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes

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A Randomized Trial of Intensive versus Standard Blood-Pressure Control

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A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management

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PLOS ONE (2015)

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Uric Acid Determination in Gestational Hypertension: Is it as Effective a Delineator of Risk as Proteinuria in High-Risk Women?

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Article Clinical Neurology

Effect of Blood Pressure Lowering in Early Ischemic Stroke Meta-Analysis

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Left Atrial Enlargement and Stroke Recurrence The Northern Manhattan Stroke Study

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STROKE (2015)

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Association of a 4-Tiered Classification of LV Hypertrophy With Adverse CV Outcomes in the General Population

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JACC-CARDIOVASCULAR IMAGING (2015)

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BMJ-BRITISH MEDICAL JOURNAL (2015)

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Article Medicine, General & Internal

Optimal systolic blood pressure target, time to intensification, and time to follow-up in treatment of hypertension: population based retrospective cohort study

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BMJ-BRITISH MEDICAL JOURNAL (2015)

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Article Medicine, General & Internal

Usual blood pressure, peripheral arterial disease, and vascular risk: cohort study of 4.2 million adults

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Article Medicine, General & Internal

Optimal systolic blood pressure target, time to intensification, and time to follow-up in treatment of hypertension: population based retrospective cohort study

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Blood Pressure Control and Risk of Stroke or Systemic Embolism in Patients With Atrial Fibrillation: Results From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

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Treatment With Multiple Blood Pressure Medications, Achieved Blood Pressure, and Mortality in Older Nursing Home Residents The PARTAGE Study

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JAMA INTERNAL MEDICINE (2015)

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Effects of Low Blood Pressure in Cognitively Impaired Elderly Patients Treated With Antihypertensive Drugs

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JAMA INTERNAL MEDICINE (2015)

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A Contemporary Appraisal of the Heart Failure Epidemic in Olmsted County, Minnesota, 2000 to 2010

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Review Obstetrics & Gynecology

Primary aldosteronism and pregnancy

Adam Morton

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NATURE REVIEWS DISEASE PRIMERS (2015)

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AGE AND AGEING (2015)

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Systematic Review and Meta-Analysis of the Prevalence of Resistant Hypertension in Treated Hypertensive Populations

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Untreated Masked Hypertension and Subclinical Cardiac Damage: A Systematic Review and Meta-analysis

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Physician (investigator) inertia in apparent treatment-resistant hypertension - Insights from large randomized clinical trials. Lennart Hansson Memorial Lecture

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Review Peripheral Vascular Disease

Prevalence of white-coat and masked hypertension in national and international registries

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HYPERTENSION RESEARCH (2015)

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Combination therapy of hypertension in the elderly: a subgroup analysis of the Combination of OLMesartan and a calcium channel blocker or diuretic in Japanese elderly hypertensive patients trial

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HYPERTENSION RESEARCH (2015)

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The global epidemiology of waterpipe smoking

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TOBACCO CONTROL (2015)

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Sandip K. Zalawadiya et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2015)

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Blood Pressure Lowering in Type 2 Diabetes A Systematic Review and Meta-analysis

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

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Randomized Comparison of Renal Denervation Versus Intensified Pharmacotherapy Including Spironolactone in True-Resistant Hypertension Six-Month Results From the Prague-15 Study

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Ocular perfusion pressure in glaucoma

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ACTA OPHTHALMOLOGICA (2014)

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Optimal Blood Pressure in Patients With Atrial Fibrillation (from the AFFIRM Trial)

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High-Risk Clinical Presentations in Atherosclerotic Renovascular Disease: Prognosis and Response to Renal Artery Revascularization

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AMERICAN JOURNAL OF KIDNEY DISEASES (2014)

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Clinical Outcomes with β-Blockers for Myocardial Infarction: A Meta-analysis of Randomized Trials

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AMERICAN JOURNAL OF MEDICINE (2014)

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The Association of Blood Pressure and Primary Open-Angle Glaucoma: A Meta-analysis

Di Zhao et al.

AMERICAN JOURNAL OF OPHTHALMOLOGY (2014)

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Diagnostic Accuracy of Point-of-Care Tests for Detecting Albuminuria

Malcolm P. McTaggart et al.

ANNALS OF INTERNAL MEDICINE (2014)

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Review Primary Health Care

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BMC FAMILY PRACTICE (2014)

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The impact of interventions by pharmacists in community pharmacies on control of hypertension: a systematic review and meta-analysis of randomized controlled trials

Ejaz Cheema et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2014)

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Review Cardiac & Cardiovascular Systems

Arterial Stiffness and Its Clinical Implications in Women

Thais Coutinho

CANADIAN JOURNAL OF CARDIOLOGY (2014)

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Ambulatory Hypertension Subtypes and 24-Hour Systolic and Diastolic Blood Pressure as Distinct Outcome Predictors in 8341 Untreated People Recruited From 12 Populations

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CIRCULATION (2014)

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Article Cardiac & Cardiovascular Systems

Chronic Hypertension in Pregnancy

Ellen W. Seely et al.

CIRCULATION (2014)

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Editorial Material Cardiac & Cardiovascular Systems

Histopathological Basis of Myocardial Late Gadolinium Enhancement in Patients With Systemic Hypertension

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CIRCULATION (2014)

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Renal Hemodynamic Effect of Sodium-Glucose Cotransporter 2 Inhibition in Patients With Type 1 Diabetes Mellitus

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DIABETOLOGIA (2014)

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EUROPEAN HEART JOURNAL (2014)

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EUROPEAN HEART JOURNAL (2014)

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EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2014)

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Chronic baroreflex activation effects on sympathetic nerve traffic, baroreflex function, and cardiac haemodynamics in heart failure: a proof-of-concept study

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EUROPEAN JOURNAL OF HEART FAILURE (2014)

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Review Pharmacology & Pharmacy

Diuretics in the treatment of hypertension. Part 2: loop diuretics and potassium-sparing agents

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EXPERT OPINION ON PHARMACOTHERAPY (2014)

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Review Psychology, Clinical

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HEALTH PSYCHOLOGY (2014)

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High rates of non-adherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry ( HP LC-MS/MS) urine analysis

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HEART (2014)

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Article Peripheral Vascular Disease

Update: Ambulatory Blood Pressure Monitoring in Children and Adolescents A Scientific Statement From the American Heart Association

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HYPERTENSION (2014)

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Long-Term Antihypertensive Treatment Fails to Improve E/e′ Despite Regression of Left Ventricular Mass An Anglo-Scandinavian Cardiac Outcomes Trial Substudy

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HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Age-Specific Differences Between Conventional and Ambulatory Daytime Blood Pressure Values

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HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Prognosis of White-Coat and Masked Hypertension International Database of Home Blood Pressure in Relation to Cardiovascular Outcome

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Article Peripheral Vascular Disease

Day-to-Day Variability in Home Blood Pressure Is Associated With Cognitive Decline The Ohasama Study

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HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Effects of the Once-Weekly Glucagon-Like Peptide-1 Receptor Agonist Dulaglutide on Ambulatory Blood Pressure and Heart Rate in Patients With Type 2 Diabetes Mellitus

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Article Peripheral Vascular Disease

Mediterranean Diet Reduces 24-Hour Ambulatory Blood Pressure, Blood Glucose, and Lipids One-Year Randomized, Clinical Trial

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Long-Term Sympathoinhibitory Effects of Surgically Induced Weight Loss in Severe Obese Patients

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HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Adjusted Drug Treatment Is Superior to Renal Sympathetic Denervation in Patients With True Treatment-Resistant Hypertension

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Article Peripheral Vascular Disease

The Impact of Malaria in Pregnancy on Changes in Blood Pressure in Children During Their First Year of Life

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HYPERTENSION (2014)

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Impaired Cardiovascular Structure and Function in Adult Survivors of Severe Acute Malnutrition

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Reference Values and Factors Associated With Renal Resistive Index in a Family-Based Population Study

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Prognostic Value of Microalbuminuria During Antihypertensive Treatment in Essential Hypertension

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Effect of Long-Term Antihypertensive Treatment on White-Coat Hypertension

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Review Peripheral Vascular Disease

Obstructive sleep apnea syndrome as a cause of resistant hypertension

Gianfranco Parati et al.

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Article Cardiac & Cardiovascular Systems

Marked sympathetic activation and baroreflex dysfunction in true resistant hypertension

Guido Grassi et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)

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Framingham score and LV mass predict events in young adults: CARDIA study

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INTERNATIONAL JOURNAL OF CARDIOLOGY (2014)

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Article Medicine, General & Internal

Effect of Self-monitoring and Medication Self-titration on Systolic Blood Pressure in Hypertensive Patients at High Risk of Cardiovascular Disease The TASMIN-SR Randomized Clinical Trial

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

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Article Peripheral Vascular Disease

Mortality and Cardiovascular Risk in Patients With a History of Malignant Hypertension: A Case-Control Study

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Review Cardiac & Cardiovascular Systems

Regression of electrocardiographic left ventricular hypertrophy or strain is associated with lower incidence of cardiovascular morbidity and mortality in hypertensive patients independent of blood pressure reduction - A LIFE review

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JOURNAL OF ELECTROCARDIOLOGY (2014)

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Article Health Care Sciences & Services

Characteristics and Long-Term Follow-Up of Participants with Peripheral Arterial Disease During ALLHAT

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JOURNAL OF GENERAL INTERNAL MEDICINE (2014)

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Review Peripheral Vascular Disease

Apparent and true resistant hypertension: definition, prevalence and outcomes

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Article Peripheral Vascular Disease

HY-Quest, standardized patient questionnaire to be completed at home before a first visit for hypertension: a validation study in specialized centres in France

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Article Peripheral Vascular Disease

Factors involved in the discontinuation of antihypertensive drug therapy: an analysis from real life data

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JOURNAL OF HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Association between serumuric acid, hypertension, vascular stiffness and subclinical atherosclerosis: data from the Brisighella Heart Study

Arrigo F. G. Cicero et al.

JOURNAL OF HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Blood pressure control and cardiovascular outcomes in normal-weight, overweight, and obese hypertensive patients treated with three different antihypertensives in ALLHAT

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JOURNAL OF HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Angiotension receptor blockers reduce the risk of dementia

Wei-Che Chiu et al.

JOURNAL OF HYPERTENSION (2014)

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Review Peripheral Vascular Disease

Cardiovascular effects of phentermine and topiramate: a newdrug combination for the treatment of obesity

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JOURNAL OF HYPERTENSION (2014)

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Editorial Material Peripheral Vascular Disease

What do we know about the risks of stopping antihypertensive treatment?

Bo Carlberg

JOURNAL OF HYPERTENSION (2014)

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Article Peripheral Vascular Disease

Prognostic value of serumuric acid: new-onset in and out-of-office hypertension and long-termmortality

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JOURNAL OF HYPERTENSION (2014)

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Review Peripheral Vascular Disease

Effects of blood pressure lowering on outcome incidence in hypertension: 3. Effects in patients at different levels of cardiovascular risk - overviewand meta-analyses of randomized trials

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JOURNAL OF HYPERTENSION (2014)

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Article Peripheral Vascular Disease

European consensus on the diagnosis and management of fibromuscular dysplasia

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Review Peripheral Vascular Disease

Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

Costas Thomopoulos et al.

JOURNAL OF HYPERTENSION (2014)

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Review Peripheral Vascular Disease

Effects of blood pressure lowering on outcome incidence in hypertension: 2. Effects at different baseline and achieved blood pressure levels - overviewand meta-analyses of randomized trials

Costas Thomopoulos et al.

JOURNAL OF HYPERTENSION (2014)

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Article Cardiac & Cardiovascular Systems

Beta-Blocker Therapy and Cardiac Events Among Patients With Newly Diagnosed Coronary Heart Disease

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

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Article Cardiac & Cardiovascular Systems

Aortic Pulse Wave Velocity Improves Cardiovascular Event Prediction An Individual Participant Meta-Analysis of Prospective Observational Data From 17,635 Subjects

Yoav Ben-Shlomo et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

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Review Peripheral Vascular Disease

Illusions of truths in the Symplicity HTN-3 trial: generic design strengths but neuroscience failings

Murray Esler

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2014)

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Review Peripheral Vascular Disease

Review of blood pressure control rates and outcomes

George Bakris et al.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2014)

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Review Urology & Nephrology

Aggressive blood pressure reduction and renin-angiotensin system blockade in chronic kidney disease: time for re-evaluation?

Pantelis A. Sarafidis et al.

KIDNEY INTERNATIONAL (2014)

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Article Medicine, General & Internal

Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study

Thomas D. Giles et al.

LANCET (2014)

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Article Medicine, General & Internal

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people

Eleni Rapsomaniki et al.

LANCET (2014)

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Article Medicine, General & Internal

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

Christian T. Ruff et al.

LANCET (2014)

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Article Respiratory System

Factors Associated with Systemic Hypertension in Asthma

Susan Ferguson et al.

LUNG (2014)

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Article Medicine, General & Internal

Association Between Alcohol Consumption and Risk of Cardiovascular Disease and All-Cause Mortality in Patients With Hypertension: A Meta-Analysis of Prospective Cohort Studies

Chao Huang et al.

MAYO CLINIC PROCEEDINGS (2014)

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Article Clinical Neurology

Intensive blood pressure reduction in acute intracerebral hemorrhage A meta-analysis

Georgios Tsivgoulis et al.

NEUROLOGY (2014)

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Article Medicine, General & Internal

Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis

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NEW ENGLAND JOURNAL OF MEDICINE (2014)

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Article Medicine, General & Internal

Spironolactone for Heart Failure with Preserved Ejection Fraction

Bertram Pitt et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

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Article Medicine, General & Internal

A Controlled Trial of Renal Denervation for Resistant Hypertension

Deepak L. Bhatt et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

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Article Medicine, General & Internal

Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events

Martin O'Donnell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

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Article Ophthalmology

Global Prevalence of Glaucoma and Projections of Glaucoma Burden through 2040 A Systematic Review and Meta-Analysis

Yih-Chung Tham et al.

OPHTHALMOLOGY (2014)

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Article Ophthalmology

Nocturnal Systemic Hypotension Increases the Risk of Glaucoma Progression

Mary E. Charlson et al.

OPHTHALMOLOGY (2014)

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Systemic Medication and Intraocular Pressure in a British Population The EPIC-Norfolk Eye Study

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OPHTHALMOLOGY (2014)

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Article Rheumatology

Gout and the Heart

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RHEUMATIC DISEASE CLINICS OF NORTH AMERICA (2014)

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Review Urology & Nephrology

Comparative Epidemiology of Resistant Hypertension in Chronic Kidney Disease and the General Hypertensive Population

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SEMINARS IN NEPHROLOGY (2014)

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Socioeconomic Inequalities in Stroke Incidence Among Migrant Groups Analysis of Nationwide Data

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STROKE (2014)

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Article Clinical Neurology

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

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STROKE (2014)

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Article Cardiac & Cardiovascular Systems

Improving Blood Pressure Control Through Pharmacist Interventions: A Meta-Analysis of Randomized Controlled Trials

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Article Cardiac & Cardiovascular Systems

Hypertension in Chronic Kidney Disease - Role of Arterial Calcification and Impact on Treatment

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EUROPEAN CARDIOLOGY REVIEW (2014)

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Review Cardiac & Cardiovascular Systems

T1 mapping: non-invasive evaluation of myocardial tissue composition by cardiovascular magnetic resonance

Anish N. Bhuva et al.

EXPERT REVIEW OF CARDIOVASCULAR THERAPY (2014)

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Article Cardiac & Cardiovascular Systems

Role of ECG in the Diagnosis of Left Ventricular Hypertrophy

Ljuba Bacharova et al.

CURRENT CARDIOLOGY REVIEWS (2014)

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Review Medicine, Research & Experimental

Hyperaldosteronism as a Common Cause of Resistant Hypertension

David A. Calhoun

ANNUAL REVIEW OF MEDICINE, VOL 64 (2013)

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Article Medicine, General & Internal

Effect of the Mediterranean diet on blood pressure in the PREDIMED trial: results from a randomized controlled trial

Estefania Toledo et al.

BMC MEDICINE (2013)

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Article Critical Care Medicine

Effects of OSA Treatment on BP in Patients With Resistant Hypertension A Randomized Trial

Rodrigo P. Pedrosa et al.

CHEST (2013)

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Article Cardiac & Cardiovascular Systems

Effects of Visit-to-Visit Variability in Systolic Blood Pressure on Macrovascular and Microvascular Complications in Patients With Type 2 Diabetes Mellitus The ADVANCE Trial

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CIRCULATION (2013)

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Elevated Blood Pressure in Pregnancy and Subsequent Chronic Disease Risk

Tuija Maennistoe et al.

CIRCULATION (2013)

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Article Cardiac & Cardiovascular Systems

Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia A Prospective Multicenter Study

Lucy C. Chappell et al.

CIRCULATION (2013)

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Article Urology & Nephrology

Prevalence of Apparent Treatment-Resistant Hypertension among Individuals with CKD

Rikki M. Tanner et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)

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Review Obstetrics & Gynecology

Blood pressure measurement prior to initiating hormonal contraception: a systematic review

Naomi K. Tepper et al.

CONTRACEPTION (2013)

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Article Critical Care Medicine

Methods of Blood Pressure Measurement in the ICU

Li-wei H. Lehman et al.

CRITICAL CARE MEDICINE (2013)

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Article Geriatrics & Gerontology

Ophthalmic Drugs as Part of Polypharmacy in Nursing Home Residents with Glaucoma

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DRUGS & AGING (2013)

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Article Cardiac & Cardiovascular Systems

Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial

Maarten Groenink et al.

EUROPEAN HEART JOURNAL (2013)

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Article Cardiac & Cardiovascular Systems

Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences

Rajiv Chowdhury et al.

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Article Clinical Neurology

Impact of blood pressure changes and course on hematoma growth in acute intracerebral hemorrhage

D. Rodriguez-Luna et al.

EUROPEAN JOURNAL OF NEUROLOGY (2013)

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Article Peripheral Vascular Disease

Substantial Reduction in Single Sympathetic Nerve Firing After Renal Denervation in Patients With Resistant Hypertension

Dagmara Hering et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Long-Term Prognostic Value of White Coat Hypertension: An Insight From Diagnostic Use of Both Ambulatory and Home Blood Pressure Measurements

Giuseppe Mancia et al.

HYPERTENSION (2013)

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Review Peripheral Vascular Disease

Isolated Nocturnal Hypertension A Disease Masked in the Dark

Yan Li et al.

HYPERTENSION (2013)

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Review Peripheral Vascular Disease

White-Coat Hypertension New Insights From Recent Studies

Stanley S. Franklin et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Prevalence of Optimal Treatment Regimens in Patients With Apparent Treatment-Resistant Hypertension Based on Office Blood Pressure in a Community-Based Practice Network

Brent M. Egan et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Initial Combination Therapy Reduces the Risk of Cardiovascular Events in Hypertensive Patients A Matched Cohort Study

Alan H. Gradman et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Masked Hypertension in Diabetes Mellitus Treatment Implications for Clinical Practice

Stanley S. Franklin et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Seasonal Blood Pressure Changes An Independent Relationship With Temperature and Daylight Hours

Pietro Amedeo Modesti et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

High Blood Pressure and Cerebral White Matter Lesion Progression in the General Population

Benjamin F. J. Verhaaren et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Does White Coat Hypertension Require Treatment Over Age 80? Results of the Hypertension in the Very Elderly Trial Ambulatory Blood Pressure Side Project

Christopher J. Bulpitt et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Outcome-Driven Thresholds for Home Blood Pressure Measurement International Database of HOme blood pressure in relation to Cardiovascular Outcome

Teemu J. Niiranen et al.

HYPERTENSION (2013)

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Article Peripheral Vascular Disease

Prevalence of microalbuminuria and associated risk factors among adult Korean hypertensive patients in a primary care setting

Yon Su Kim et al.

HYPERTENSION RESEARCH (2013)

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Article Medicine, General & Internal

Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries

Clara K. Chow et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

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Article Medicine, General & Internal

Effects of Individual Physician-Level and Practice-Level Financial Incentives on Hypertension Care A Randomized Trial

Laura A. Petersen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

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Article Medicine, General & Internal

Natriuretic Peptide-Based Screening and Collaborative Care for Heart Failure The STOP-HF Randomized Trial

Mark Ledwidge et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)

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Review Peripheral Vascular Disease

Effect of Allopurinol on Blood Pressure: A Systematic Review and Meta-Analysis

Vikram Agarwal et al.

JOURNAL OF CLINICAL HYPERTENSION (2013)

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Article Peripheral Vascular Disease

European Society of Hypertension Position Paper on Ambulatory Blood Pressure Monitoring

Eoin O'Brien et al.

JOURNAL OF HYPERTENSION (2013)

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Review Peripheral Vascular Disease

The unappreciated importance of blood pressure in recent and older atrial fibrillation trials

Athanasios Manolis et al.

JOURNAL OF HYPERTENSION (2013)

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Review Peripheral Vascular Disease

Endurance exercise beneficially affects ambulatory blood pressure: a systematic review and meta-analysis

Veronique A. Cornelissen et al.

JOURNAL OF HYPERTENSION (2013)

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Article Peripheral Vascular Disease

2013 ESH/ESC Guidelines for themanagement of arterial hypertension The Task Force for the management ofarterial hypertension of the European Society ofHypertension (ESH) and of the European Society of Cardiology (ESC)

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JOURNAL OF HYPERTENSION (2013)

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Article Cardiac & Cardiovascular Systems

Prevalence and Prognostic Role of Resistant Hypertension in Chronic Kidney Disease Patients

Luca De Nicola et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

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Article Cardiac & Cardiovascular Systems

The Relationship Between Metabolic Risk Factors and Incident Cardiovascular Disease in Europeans, South Asians, and African Caribbeans SABRE (Southall and Brent Revisited)-A Prospective Population-Based Study

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

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Article Cardiac & Cardiovascular Systems

A Meta-Analysis Reporting Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Patients Without Heart Failure

Gianluigi Savarese et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

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Article Urology & Nephrology

Adherence to antihypertensive agents improves risk reduction of end-stage renal disease

Louise Roy et al.

KIDNEY INTERNATIONAL (2013)

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Article Medicine, General & Internal

Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial

Michael A. Weber et al.

LANCET (2013)

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Article Medicine, General & Internal

Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial

O. R. Benavente et al.

LANCET (2013)

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Review Urology & Nephrology

Orthostatic hypertension-a new haemodynamic cardiovascular risk factor

Kazuomi Kario

NATURE REVIEWS NEPHROLOGY (2013)

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Combined Angiotensin Inhibition for the Treatment of Diabetic Nephropathy

Linda F. Fried et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

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Article Medicine, General & Internal

Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage

Craig S. Anderson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

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Article Endocrinology & Metabolism

A Randomized, Phase 3 Trial of Naltrexone SR/Bupropion SR on Weight and Obesity-related Risk Factors (COR-II)

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OBESITY (2013)

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Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort

Joy Miller et al.

RESPIRATORY MEDICINE (2013)

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Article Clinical Neurology

Effects of treatment with oral appliance on 24-h blood pressure in patients with obstructive sleep apnea and hypertension: a randomized clinical trial

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SLEEP AND BREATHING (2013)

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Article Clinical Neurology

Feasibility of an Ambulance-Based Stroke Trial, and Safety of Glyceryl Trinitrate in Ultra-Acute Stroke The Rapid Intervention With Glyceryl Trinitrate in Hypertensive Stroke Trial (RIGHT, ISRCTN66434824)

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STROKE (2013)

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Article Clinical Neurology

Systolic Blood Pressure After Intravenous Antihypertensive Treatment and Clinical Outcomes in Hyperacute Intracerebral Hemorrhage The Stroke Acute Management With Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study

Yuki Sakamoto et al.

STROKE (2013)

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Review Medicine, General & Internal

Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses

Nancy J. Aburto et al.

BMJ-BRITISH MEDICAL JOURNAL (2013)

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Review Cardiac & Cardiovascular Systems

Exercise Training for Blood Pressure: A Systematic Review and Meta-analysis

Veronique A. Cornelissen et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)

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Management of cardiac toxicity in patients receiving vascular endothelial growth factor signaling pathway inhibitors

Richard M. Steingart et al.

AMERICAN HEART JOURNAL (2012)

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Article Cardiac & Cardiovascular Systems

Usefulness of Heart Rate to Predict Cardiac Events in Treated Patients With High-Risk Systemic Hypertension

Stevo Julius et al.

AMERICAN JOURNAL OF CARDIOLOGY (2012)

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Article Peripheral Vascular Disease

Incidence of Cardiovascular Events in Italian Patients With Early Discontinuations of Antihypertensive, Lipid-Lowering, and Antidiabetic treatments

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AMERICAN JOURNAL OF HYPERTENSION (2012)

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Review Peripheral Vascular Disease

Effects of Low-Sodium Diet vs. High-Sodium Diet on Blood Pressure, Renin, Aldosterone, Catecholamines, Cholesterol, and Triglyceride (Cochrane Review)

Niels A. Graudal et al.

AMERICAN JOURNAL OF HYPERTENSION (2012)

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Article Medicine, General & Internal

Angiotensin II Receptor Blocker-based Therapy in Japanese Elderly, High-risk, Hypertensive Patients

Hisao Ogawa et al.

AMERICAN JOURNAL OF MEDICINE (2012)

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Article Medicine, General & Internal

Adherence to Drugs That Prevent Cardiovascular Disease: Meta-analysis on 376,162 Patients

Sayed H. Naderi et al.

AMERICAN JOURNAL OF MEDICINE (2012)

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Inflammatory Biomarkers and Comorbidities in Chronic Obstructive Pulmonary Disease

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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)

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Review Rheumatology

How early in the course of rheumatoid arthritis does the excess cardiovascular risk appear?

Anne M. Kerola et al.

ANNALS OF THE RHEUMATIC DISEASES (2012)

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Article Medicine, General & Internal

Rethinking the Association of High Blood Pressure With Mortality in Elderly Adults The Impact of Frailty

Michelle C. Odden et al.

ARCHIVES OF INTERNAL MEDICINE (2012)

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Review Cardiac & Cardiovascular Systems

Ambulatory arterial stiffness index: A systematic review and meta-analysis

Anastasios Kollias et al.

ATHEROSCLEROSIS (2012)

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Article Cardiac & Cardiovascular Systems

Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: A meta-analysis

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ATHEROSCLEROSIS (2012)

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Review Cardiac & Cardiovascular Systems

Angiotensin converting enzyme inhibitors effect on arterial stiffness and wave reflections: A meta-analysis and meta-regression of randomised controlled trials

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ATHEROSCLEROSIS (2012)

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Article Peripheral Vascular Disease

Effects of the time of antihypertensive drugs administration on the stage of primary open-angle glaucoma in patients with arterial hypertension

Beata Krasinska et al.

BLOOD PRESSURE (2012)

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Article Surgery

Meta-analysis of individual patient data to examine factors affecting growth and rupture of small abdominal aortic aneurysms

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BRITISH JOURNAL OF SURGERY (2012)

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Article Clinical Neurology

Mannheim Carotid Intima-Media Thickness and Plaque Consensus (2004-2006-2011) An Update on Behalf of the Advisory Board of the 3rd, 4th and 5th Watching the Risk Symposia, at the 13th, 15th and 20th European Stroke Conferences, Mannheim, Germany, 2004, Brussels, Belgium, 2006, and Hamburg, Germany, 2011

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CEREBROVASCULAR DISEASES (2012)

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Article Cardiac & Cardiovascular Systems

Incidence and Prognosis of Resistant Hypertension in Hypertensive Patients

Stacie L. Daugherty et al.

CIRCULATION (2012)

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Article Cardiac & Cardiovascular Systems

Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF) Trial

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CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2012)

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Article Urology & Nephrology

Prevalence and Factors Associated with Hyperkalemia in Predialysis Patients Followed in a Low-Clearance Clinic

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CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2012)

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Article Cardiac & Cardiovascular Systems

Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of reninangiotensinaldosterone system inhibitors involving 158 998 patients

Laura C. van Vark et al.

EUROPEAN HEART JOURNAL (2012)

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Review Endocrinology & Metabolism

Pheochromocytoma and pregnancy: a deceptive connection

Jacques W. M. Lenders

EUROPEAN JOURNAL OF ENDOCRINOLOGY (2012)

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Article Biochemistry & Molecular Biology

Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension

Idris Guessous et al.

HUMAN MOLECULAR GENETICS (2012)

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Article Peripheral Vascular Disease

Catheter-Based Renal Nerve Ablation and Centrally Generated Sympathetic Activity in Difficult-to-Control Hypertensive Patients Prospective Case Series

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HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Upper Normal Blood Pressures Predict Incident Atrial Fibrillation in Healthy Middle-Aged Men A 35-Year Follow-Up Study

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HYPERTENSION (2012)

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Editorial Material Peripheral Vascular Disease

Short- and Long-Term Blood Pressure Variability Present and Future

Giuseppe Mancia

HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Initial Monotherapy and Combination Therapy and Hypertension Control the First Year

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Article Peripheral Vascular Disease

Blood Pressure and Risk of Cancer Incidence and Mortality in the Metabolic Syndrome and Cancer Project

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HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Blood Pressure Tracking Over the Adult Life Course Patterns and Correlates in the Framingham Heart Study

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HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Ambulatory Blood Pressure Values in the Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET)

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HYPERTENSION (2012)

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Article Medicine, General & Internal

Aortic Stiffness, Blood Pressure Progression, and Incident Hypertension

Bernhard M. Kaess et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Medicine, General & Internal

Comparison of Risk Prediction Using the CKD-EPI Equation and the MDRD Study Equation for Estimated Glomerular Filtration Rate

Kunihiro Matsushita et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Medicine, General & Internal

Bariatric Surgery and Long-term Cardiovascular Events

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Medicine, General & Internal

Common Carotid Intima-Media Thickness Measurements in Cardiovascular Risk Prediction A Meta-analysis

Hester M. Den Ruijter et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Medicine, General & Internal

Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals

Joseph Yeboah et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2012)

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Article Endocrinology & Metabolism

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)

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Review Peripheral Vascular Disease

The Hypertension Team: The Role of the Pharmacist, Nurse, and Teamwork in Hypertension Therapy

Barry L. Carter et al.

JOURNAL OF CLINICAL HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Impact of the Number of Blood Pressure Measurements on Blood Pressure Classification in US Adults: NHANES 1999-2008

Joel Handler et al.

JOURNAL OF CLINICAL HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Within-Visit Variability of Blood Pressure and All-Cause and Cardiovascular Mortality Among US Adults

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JOURNAL OF CLINICAL HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Ambulatory arterial stiffness index does not accurately assess arterial stiffness

Jan G. Kips et al.

JOURNAL OF HYPERTENSION (2012)

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Review Peripheral Vascular Disease

Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies

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JOURNAL OF HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and difficult to treat arterial hypertension

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JOURNAL OF HYPERTENSION (2012)

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Editorial Material Peripheral Vascular Disease

Longing for clinical excellence: a critical outlook into the NICE recommendations on hypertension management - is nice always good?

Alberto Zanchetti et al.

JOURNAL OF HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Requirements for professional office blood pressure monitors

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Article Peripheral Vascular Disease

Impact of lower achieved blood pressure on outcomes in hypertensive patients

Peter M. Okin et al.

JOURNAL OF HYPERTENSION (2012)

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Article Peripheral Vascular Disease

Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity

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JOURNAL OF HYPERTENSION (2012)

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Article Cardiac & Cardiovascular Systems

Safety and Efficacy of Low Blood Pressures Among Patients With Diabetes Subgroup Analyses From the ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial)

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)

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Article Cardiac & Cardiovascular Systems

Eplerenone and Atrial Fibrillation in Mild Systolic Heart Failure Results From the EMPHASIS-HF (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure) Study

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)

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Article Cardiac & Cardiovascular Systems

EAE/ASE Recommendations for Image Acquisition and Display Using Three-Dimensional Echocardiography

Roberto M. Lang et al.

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY (2012)

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Article Medicine, General & Internal

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis

Caroline S. Fox et al.

LANCET (2012)

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Article Medicine, General & Internal

Association of a difference in systolic blood pressure between arms with vascular disease and mortality: a systematic review and meta-analysis

Christopher E. Clark et al.

LANCET (2012)

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Editorial Material Medicine, General & Internal

Everyone under statin?

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EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE (2012)

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Article Medicine, General & Internal

Thrombotic Stroke and Myocardial Infarction with Hormonal Contraception

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NEW ENGLAND JOURNAL OF MEDICINE (2012)

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Article Medicine, General & Internal

Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes

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NEW ENGLAND JOURNAL OF MEDICINE (2012)

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Article Urology & Nephrology

Major Barriers against Renin-Angiotensin-Aldosterone System Blocker Use in Chronic Kidney Disease Stages 3-5 in Clinical Practice: A Safety Concern?

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RENAL FAILURE (2012)

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Article Clinical Neurology

Increased Cerebral Arterial Pulsatility in Patients With Leukoaraiosis Arterial Stiffness Enhances Transmission of Aortic Pulsatility

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STROKE (2012)

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Article Clinical Neurology

Relation Between Change in Blood Pressure in Acute Stroke and Risk of Early Adverse Events and Poor Outcome

Else C. Sandset et al.

STROKE (2012)

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Article Medicine, General & Internal

Assessing the risk of venous thromboembolic events in women taking progestin-only contraception: a meta-analysis

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BMJ-BRITISH MEDICAL JOURNAL (2012)

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Article Obstetrics & Gynecology

Transient gestational hypertension: Not always a benign event

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PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH (2012)

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Article Medicine, General & Internal

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

B. Mihaylova et al.

LANCET (2012)

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Article Medicine, General & Internal

Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study

Hyon K. Choi et al.

BRITISH MEDICAL JOURNAL (2012)

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Article Medicine, General & Internal

Attributable Risk Estimate of Severe Psoriasis on Major Cardiovascular Events

Nehal N. Mehta et al.

AMERICAN JOURNAL OF MEDICINE (2011)

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Article Anesthesiology

Invasive and Concomitant Noninvasive Intraoperative Blood Pressure Monitoring Observed Differences in Measurements and Associated Therapeutic Interventions

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ANESTHESIOLOGY (2011)

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Article Medicine, General & Internal

Encounter Frequency and Serum Glucose Level, Blood Pressure, and Cholesterol Level Control in Patients With Diabetes Mellitus

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ARCHIVES OF INTERNAL MEDICINE (2011)

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Review Medicine, General & Internal

Impact of Pharmacist Care in the Management of Cardiovascular Disease Risk Factors A Systematic Review and Meta-analysis of Randomized Trials

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ARCHIVES OF INTERNAL MEDICINE (2011)

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Article Clinical Neurology

Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility - Reykjavik Study

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BRAIN (2011)

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Article Cardiac & Cardiovascular Systems

Mild Retinopathy Is a Risk Factor for Cardiovascular Mortality in Japanese With and Without Hypertension The Ibaraki Prefectural Health Study

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CIRCULATION (2011)

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Article Cardiac & Cardiovascular Systems

Antihypertensive Treatment and Change in Blood Pressure Are Associated With the Progression of White Matter Lesion Volumes The Three-City (3C)-Dijon Magnetic Resonance Imaging Study

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CIRCULATION (2011)

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Article Cardiac & Cardiovascular Systems

Dose Response Between Physical Activity and Risk of Coronary Heart Disease A Meta-Analysis

Jacob Sattelmair et al.

CIRCULATION (2011)

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Article Cardiac & Cardiovascular Systems

Effectiveness-Based Guidelines for the Prevention of Cardiovascular Disease in Women—2011 Update

Lori Mosca et al.

CIRCULATION (2011)

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Article Cardiac & Cardiovascular Systems

Blood Pressure Targets in Subjects With Type 2 Diabetes Mellitus/Impaired Fasting Glucose Observations From Traditional and Bayesian Random-Effects Meta-Analyses of Randomized Trials

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Article Cardiac & Cardiovascular Systems

Blood Pressure Targets Recommended by Guidelines and Incidence of Cardiovascular and Renal Events in the Ongoing Telmisartan Alone and in Combination With Ramipril Global Endpoint Trial (ONTARGET)

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CIRCULATION (2011)

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Editorial Material Clinical Neurology

Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome

Roy Freeman et al.

CLINICAL AUTONOMIC RESEARCH (2011)

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Article Cardiac & Cardiovascular Systems

Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials

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EUROPEAN HEART JOURNAL (2011)

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Review Cardiac & Cardiovascular Systems

Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies

Francesco P. Cappuccio et al.

EUROPEAN HEART JOURNAL (2011)

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Article Cardiac & Cardiovascular Systems

Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications Endorsed by the Japanese Society of Echocardiography

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EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY (2011)

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Article Ophthalmology

The complex interaction between ocular perfusion pressure and ocular blood flow - Relevance for glaucoma

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Article Peripheral Vascular Disease

Cardiovascular Protection by Initial and Subsequent Combination of Antihypertensive Drugs in Daily Life Practice

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HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Clinical Features of 8295 Patients With Resistant Hypertension Classified on the Basis of Ambulatory Blood Pressure Monitoring

Alejandro de la Sierra et al.

HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Role of Home Blood Pressure Monitoring in Overcoming Therapeutic Inertia and Improving Hypertension Control A Systematic Review and Meta-Analysis

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HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Ambulatory Blood Pressure Monitoring in 9357 Subjects From 11 Populations Highlights Missed Opportunities for Cardiovascular Prevention in Women

Jose Boggia et al.

HYPERTENSION (2011)

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Article Peripheral Vascular Disease

β-Blockers in Patients With Intermittent Claudication and Arterial Hypertension Results From the Nebivolol or Metoprolol in Arterial Occlusive Disease Trial

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Article Peripheral Vascular Disease

Early Sympathetic Activation in the Initial Clinical Stages of Chronic Renal Failure

Guido Grassi et al.

HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Ethnic Differences in Aortic Pulse Wave Velocity Occur in the Descending Aorta and May Be Related to Vitamin D

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HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Obstructive Sleep Apnea The Most Common Secondary Cause of Hypertension Associated With Resistant Hypertension

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HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Impact of Resistance Training on Blood Pressure and Other Cardiovascular Risk Factors A Meta-Analysis of Randomized, Controlled Trials

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HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Are blood pressure and diabetes additive or synergistic risk factors? Outcome in 8494 subjects randomly recruited from 10 populations

Thomas Sehestedt et al.

HYPERTENSION RESEARCH (2011)

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Review Medicine, General & Internal

Antihypertensive Treatment and Secondary Prevention of Cardiovascular Disease Events Among Persons Without Hypertension A Meta-analysis

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2011)

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Article Rheumatology

Traditional cardiovascular risk factors in rheumatoid arthritis: A meta-analysis

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JOINT BONE SPINE (2011)

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Article Health Care Sciences & Services

GRADE guidelines: 3. Rating the quality of evidence

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JOURNAL OF CLINICAL EPIDEMIOLOGY (2011)

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Review Peripheral Vascular Disease

PROGRESS: Prevention of Recurrent Stroke

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JOURNAL OF CLINICAL HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Characteristics of resistant hypertension: ageing, body mass index, hyperaldosteronism, cardiac hypertrophy and vascular stiffness

L. C. Martins et al.

JOURNAL OF HUMAN HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Heterogeneity in antihypertensive treatment discontinuation between drugs belonging to the same class

Giuseppe Mancia et al.

JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Blood pressure control by the nifedipine GITS-telmisartan combination in patients at high cardiovascular risk: the TALENT study

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JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Endothelial dysfunction, platelet activation, thrombogenesis and fibrinolysis in patients with hypertensive crisis

Bert-Jan H. van den Born et al.

JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Isolated systolic hypertension of young-to-middle-age individuals implies a relatively low risk of developing hypertension needing treatment when central blood pressure is low

Francesca Saladini et al.

JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

The significance of low DBP in US adults with isolated systolic hypertension

Stanley S. Franklin et al.

JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Impact of amlodipine-based therapy among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA)

David J. Collier et al.

JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Better compliance to antihypertensive medications reduces cardiovascular risk

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JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial

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JOURNAL OF HYPERTENSION (2011)

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Article Peripheral Vascular Disease

Baseline predictors of resistant hypertension in the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT): a risk score to identify those at high-risk

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JOURNAL OF HYPERTENSION (2011)

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Article Primary Health Care

Do Clinicians Tell Patients They Have Prehypertension?

Anthony J. Viera et al.

JOURNAL OF THE AMERICAN BOARD OF FAMILY MEDICINE (2011)

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Article Cardiac & Cardiovascular Systems

Baroreflex Activation Therapy Lowers Blood Pressure in Patients With Resistant Hypertension Results From the Double-Blind, Randomized, Placebo-Controlled Rheos Pivotal Trial

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)

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Editorial Material Urology & Nephrology

The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report

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KIDNEY INTERNATIONAL (2011)

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Article Urology & Nephrology

Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts

Brad C. Astor et al.

KIDNEY INTERNATIONAL (2011)

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Article Medicine, General & Internal

The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial

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LANCET (2011)

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Review Multidisciplinary Sciences

Progress and challenges in translating the biology of atherosclerosis

Peter Libby et al.

NATURE (2011)

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Article Medicine, General & Internal

Carotid-Wall Intima-Media Thickness and Cardiovascular Events

Joseph F. Polak et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

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Article Medicine, General & Internal

Olmesartan for the Delay or Prevention of Microalbuminuria in Type 2 Diabetes

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NEW ENGLAND JOURNAL OF MEDICINE (2011)

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Article Oncology

Posterior reversible encephalopathy syndrome induced by anti-VEGF agents

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TARGETED ONCOLOGY (2011)

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Article Medicine, General & Internal

Life Course Trajectories of Systolic Blood Pressure Using Longitudinal Data from Eight UK Cohorts

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PLOS MEDICINE (2011)

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Article Medicine, General & Internal

Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9

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BMJ-BRITISH MEDICAL JOURNAL (2011)

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Article Cardiac & Cardiovascular Systems

Usefulness of Heart Rate at Rest as a Predictor of Mortality, Hospitalization for Heart Failure, Myocardial Infarction, and Stroke in Patients With Stable Coronary Heart Disease (Data from the Treating to New Targets [TNT] Trial)

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AMERICAN JOURNAL OF CARDIOLOGY (2010)

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Article Nutrition & Dietetics

Accruing evidence on benefits of adherence to the Mediterranean diet on health an updated systematic review and meta-analysis

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AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)

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Article Peripheral Vascular Disease

Relationship of Self-Reported Alcohol Consumption to Ambulatory Blood Pressure in a Sample of Healthy Adults

Jerome L. Abramson et al.

AMERICAN JOURNAL OF HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Increased Risk of High-Grade Hypertension With Bevacizumab in Cancer Patients: A. Meta-Analysis

Vishal Ranpura et al.

AMERICAN JOURNAL OF HYPERTENSION (2010)

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Article Medicine, General & Internal

Angiotensin-converting Enzyme-related Cough among Chinese-Americans

Daniel S. Tseng et al.

AMERICAN JOURNAL OF MEDICINE (2010)

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Review Physiology

Translational medicine: the antihypertensive effect of renal denervation

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AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)

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Article Critical Care Medicine

A Novel User-Friendly Score (HAS-BLED) To Assess 1-Year Risk of Major Bleeding in Patients With Atrial Fibrillation The Euro Head Survey

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CHEST (2010)

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Article Peripheral Vascular Disease

Chronic Psychosocial Stress and Hypertension

Tanya M. Spruill

CURRENT HYPERTENSION REPORTS (2010)

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Risk prediction is improved by adding markers of subclinical organ damage to SCORE

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EUROPEAN HEART JOURNAL (2010)

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Article Cardiac & Cardiovascular Systems

Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS)

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EUROPEAN HEART JOURNAL (2010)

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Article Cardiac & Cardiovascular Systems

J-curve revisited: an analysis of blood pressure and cardiovascular events in the Treating to New Targets (TNT) Trial†

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EUROPEAN HEART JOURNAL (2010)

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Article Cardiac & Cardiovascular Systems

Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: 'establishing normal and reference values'

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EUROPEAN HEART JOURNAL (2010)

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Review Pharmacology & Pharmacy

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EXPERT OPINION ON DRUG SAFETY (2010)

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FAMILY PRACTICE (2010)

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Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly Valsartan in Elderly Isolated Systolic Hypertension Study

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Article Peripheral Vascular Disease

Encounter Frequency and Blood Pressure in Hypertensive Patients With Diabetes Mellitus

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HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Effects of the Dietary Approaches to Stop Hypertension Diet Alone and in Combination With Exercise and Caloric Restriction on Insulin Sensitivity and Lipids

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HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Amlodipine-Valsartan Combination Decreases Central Systolic Blood Pressure More Effectively Than the Amlodipine-Atenolol Combination The EXPLOR Study

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HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Carotid Baroreceptor Stimulation, Sympathetic Activity, Baroreflex Function, and Blood Pressure in Hypertensive Patients

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HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Accuracy of a single rigid conical cuff with standard-size bladder coupled to an automatic oscillometric device over a wide range of arm circumferences

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HYPERTENSION RESEARCH (2010)

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Article Peripheral Vascular Disease

Prehypertension in disease-free adults: a marker for an adverse cardiometabolic risk profile

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HYPERTENSION RESEARCH (2010)

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Article Peripheral Vascular Disease

Residual cardiovascular risk in treated hypertension and hyperlipidaemia: the PRIME Study

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JOURNAL OF HUMAN HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Factors associated with therapeutic inertia in hypertension: validation of a predictive model

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JOURNAL OF HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Reduced discontinuation of antihypertensive treatment by two-drug combination as first step. Evidence from daily life practice

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JOURNAL OF HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Prevalence and determinants of isolated systolic hypertension among young adults: the 1999-2004 US National Health And Nutrition Examination Survey

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Article Peripheral Vascular Disease

Long-term reduction in aortic stiffness: a 5.3-year follow-up in routine clinical practice

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JOURNAL OF HYPERTENSION (2010)

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Article Peripheral Vascular Disease

Prognostic value of isolated nocturnal hypertension on ambulatory measurement in 8711 individuals from 10 populations

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JOURNAL OF HYPERTENSION (2010)

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Editorial Material Cardiac & Cardiovascular Systems

Understanding Radiation-Induced Vascular Disease

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

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Article Cardiac & Cardiovascular Systems

Alcohol Consumption and Cardiovascular Mortality Among US Adults, 1987 to 2002

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

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Article Cardiac & Cardiovascular Systems

Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk The ARIC (Atherosclerosis Risk In Communities) Study

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

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Article Cardiac & Cardiovascular Systems

Does Carotid Intima-Media Thickness Regression Predict Reduction of Cardiovascular Events? A Meta-Analysis of 41 Randomized Trials

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

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Article Cardiac & Cardiovascular Systems

Prevention of Atrial Fibrillation by Renin-Angiotensin System Inhibition A Meta-Analysis

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)

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Article Urology & Nephrology

Bevacizumab Increases Risk for Severe Proteinuria in Cancer Patients

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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)

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Article Surgery

An analysis of drug modulation of abdominal aortic aneurysm growth through 25 years of surveillance

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JOURNAL OF VASCULAR SURGERY (2010)

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Article Medicine, General & Internal

Telemonitoring and self-management in the control of hypertension (TASMINH2): a randomised controlled trial

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LANCET (2010)

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Article Medicine, General & Internal

Prognostic significance of visit-to-visit variability, maximum systolic blood pressure, and episodic hypertension

Peter M. Rothwell et al.

LANCET (2010)

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Article Medicine, General & Internal

Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study

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LANCET (2010)

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Article Medicine, General & Internal

Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial

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LANCET (2010)

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Article Clinical Neurology

Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): a prospective, randomised, open, blinded-endpoint trial

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LANCET NEUROLOGY (2010)

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Article Clinical Neurology

Afferent baroreflex failure in familial dysautonomia

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NEUROLOGY (2010)

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Article Medicine, General & Internal

Intensive Blood-Pressure Control in Hypertensive Chronic Kidney Disease

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NEW ENGLAND JOURNAL OF MEDICINE (2010)

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Article Medicine, General & Internal

Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events

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NEW ENGLAND JOURNAL OF MEDICINE (2010)

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Article Medicine, General & Internal

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management.

Steven R. Smith et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

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Article Medicine, General & Internal

Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus

William C. Cushman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

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Review Immunology

Steroid Avoidance or Withdrawal After Renal Transplantation Increases the Risk of Acute Rejection but Decreases Cardiovascular Risk. A Meta-Analysis

Simon R. Knight et al.

TRANSPLANTATION (2010)

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Article Oncology

Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis

Xiaolei Zhu et al.

ACTA ONCOLOGICA (2009)

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Article Peripheral Vascular Disease

Improving Survival of Malignant Hypertension Patients Over 40 Years

Deirdre A. Lane et al.

AMERICAN JOURNAL OF HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Natural History of Hypertension Subtypes in Young and Middle-Age Adults

Francesca Saladini et al.

AMERICAN JOURNAL OF HYPERTENSION (2009)

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Article Medicine, General & Internal

Combination Therapy Versus Monotherapy in Reducing Blood Pressure: Meta-analysis on 11,000 Participants from 42 Trials

David S. Wald et al.

AMERICAN JOURNAL OF MEDICINE (2009)

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Editorial Material Anesthesiology

Perioperative beta-Blockade, Discontinuation, and Complications Do You Really Know It When You See It?

Martin J. London

ANESTHESIOLOGY (2009)

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Article Medicine, General & Internal

Stent Placement in Patients With Atherosclerotic Renal Artery Stenosis and Impaired Renal Function A Randomized Trial

Liesbeth Bax et al.

ANNALS OF INTERNAL MEDICINE (2009)

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Article Medicine, General & Internal

A New Equation to Estimate Glomerular Filtration Rate

Andrew S. Levey et al.

ANNALS OF INTERNAL MEDICINE (2009)

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Article Medicine, General & Internal

Incarceration, Incident Hypertension, and Access to Health Care Findings From the Coronary Artery Risk Development in Young Adults (CARDIA) Study

Emily A. Wang et al.

ARCHIVES OF INTERNAL MEDICINE (2009)

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Article Medicine, General & Internal

The Frequency of Hyperkalemia and Its Significance in Chronic Kidney Disease

Lisa M. Einhorn et al.

ARCHIVES OF INTERNAL MEDICINE (2009)

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Review Medicine, General & Internal

The Potency of Team-Based Care Interventions for Hypertension A Meta-analysis

Barry L. Carter et al.

ARCHIVES OF INTERNAL MEDICINE (2009)

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Article Rheumatology

The Safety and Efficacy of a JAK Inhibitor in Patients With Active Rheumatoid Arthritis Results of a Double-Blind, Placebo-Controlled Phase IIa Trial of Three Dosage Levels of CP-690,550 Versus Placebo

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ARTHRITIS AND RHEUMATISM (2009)

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Article Cardiac & Cardiovascular Systems

Adherence to Antihypertensive Medications and Cardiovascular Morbidity Among Newly Diagnosed Hypertensive Patients

Giampiero Mazzaglia et al.

CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Single Versus Combined Blood Pressure Components and Risk for Cardiovascular Disease The Framingham Heart Study

Stanley S. Franklin et al.

CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Influence of Systolic and Diastolic Blood Pressure on the Risk of Incident Atrial Fibrillation in Women

David Conen et al.

CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Baseline Values but Not Treatment-Induced Changes in Carotid Intima-Media Thickness Predict Incident Cardiovascular Events in Treated Hypertensive Patients Findings in the European Lacidipine Study on Atherosclerosis (ELSA)

Alberto Zanchetti et al.

CIRCULATION (2009)

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Article Cardiac & Cardiovascular Systems

Prognostic Value of Changes in the Electrocardiographic Strain Pattern During Antihypertensive Treatment The Losartan Intervention for End-Point Reduction in Hypertension Study (LIFE)

Peter M. Okin et al.

CIRCULATION (2009)

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Article Surgery

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EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY (2009)

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Article Peripheral Vascular Disease

Hypertensive Pregnancy Disorders and Subsequent Cardiovascular Morbidity and Type 2 Diabetes Mellitus in the Mother

Jacob A. Lykke et al.

HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Long-Term Risk of Sustained Hypertension in White-Coat or Masked Hypertension

Giuseppe Mancia et al.

HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Effects of Dietary Sodium Reduction on Blood Pressure in Subjects With Resistant Hypertension Results From a Randomized Trial

Eduardo Pimenta et al.

HYPERTENSION (2009)

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Article Peripheral Vascular Disease

ASH Position Paper: Hypertension in Pregnancy

Marshall D. Lindheimer et al.

JOURNAL OF CLINICAL HYPERTENSION (2009)

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Review Peripheral Vascular Disease

The prevalence of atherosclerotic renal artery stenosis in risk groups: a systematic literature review

Quirijn de Mast et al.

JOURNAL OF HYPERTENSION (2009)

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Review Peripheral Vascular Disease

Bottom blood pressure or bottom cardiovascular risk? How far can cardiovascular risk be reduced?

Alberto Zanchetti

JOURNAL OF HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Left ventricular hypertrophy increases cardiovascular risk independently of in-office and out-of-office blood pressure values

Michele Bombelli et al.

JOURNAL OF HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Increased long-term risk of new-onset diabetes mellitus in white-coat and masked hypertension

Giuseppe Mancia et al.

JOURNAL OF HYPERTENSION (2009)

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Article Peripheral Vascular Disease

Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial study

Peter Sleight et al.

JOURNAL OF HYPERTENSION (2009)

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Review Peripheral Vascular Disease

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

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JOURNAL OF HYPERTENSION (2009)

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Article Cardiac & Cardiovascular Systems

Effect of Spironolactone on Left Ventricular Mass and Aortic Stiffness in Early-Stage Chronic Kidney Disease A Randomized Controlled Trial

Nicola C. Edwards et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2009)

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Review Urology & Nephrology

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Sharon E. Maynard et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)

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Article Urology & Nephrology

Change in Estimated GFR Associates with Coronary Heart Disease and Mortality

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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)

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Article Urology & Nephrology

Addition of Angiotensin Receptor Blockade or Mineralocorticoid Antagonism to Maximal Angiotensin-Converting Enzyme Inhibition in Diabetic Nephropathy

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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)

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Article Medicine, General & Internal

Revascularization versus Medical Therapy for Renal-Artery Stenosis

NEW ENGLAND JOURNAL OF MEDICINE (2009)

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Article Medicine, General & Internal

Strict Blood-Pressure Control and Progression of Renal Failure in Children

NEW ENGLAND JOURNAL OF MEDICINE (2009)

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Article Clinical Neurology

Effect of Telmisartan on Functional Outcome, Recurrence, and Blood Pressure in Patients With Acute Mild Ischemic Stroke A PRoFESS Subgroup Analysis

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STROKE (2009)

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Article Clinical Neurology

Relationship of Blood Pressure, Antihypertensive Therapy, and Outcome in Ischemic Stroke Treated With Intravenous Thrombolysis Retrospective Analysis From Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR)

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STROKE (2009)

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Article Medicine, General & Internal

The Preventable Causes of Death in the United States: Comparative Risk Assessment of Dietary, Lifestyle, and Metabolic Risk Factors

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PLOS MEDICINE (2009)

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Article Medicine, General & Internal

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

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BMJ-BRITISH MEDICAL JOURNAL (2009)

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Article Public, Environmental & Occupational Health

Blood pressure and risk of renal cell carcinoma in the european prospective investigation into cancer and nutrition

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AMERICAN JOURNAL OF EPIDEMIOLOGY (2008)

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Article Peripheral Vascular Disease

Effects of renin-angiotensin system blockers on renal outcomes and all-cause mortality in patients with diabetic nephropathy: An updated meta-analysis

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AMERICAN JOURNAL OF HYPERTENSION (2008)

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Article Medicine, General & Internal

Gender Differences in Office and Ambulatory Control of Hypertension

Jose R. Banegas et al.

AMERICAN JOURNAL OF MEDICINE (2008)

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Article Rheumatology

Do cardiovascular risk factors confer the same risk for cardiovascular outcomes in rheumatoid arthritis patients as in non-rheumatoid arthritis patients?

A. Gonzalez et al.

ANNALS OF THE RHEUMATIC DISEASES (2008)

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Article Medicine, General & Internal

Characterization of resistant hypertension - Association between resistant hypertension, aldosterone, and persistent intravascular volume expansion

Krishna K. Gaddam et al.

ARCHIVES OF INTERNAL MEDICINE (2008)

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Article Cardiac & Cardiovascular Systems

Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis

Andreas J. Flammer et al.

CIRCULATION (2008)

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Reprint Cardiac & Cardiovascular Systems

Resistant hypertension: Diagnosis, evaluation, and treatment - A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research (Reprinted from Hypertension, vol 51, pg 1403-1419, 2008)

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CIRCULATION (2008)

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Article Peripheral Vascular Disease

Simultaneous Measurement of Beat-to-Beat Carotid Diameter and Pressure Changes to Assess Arterial Mechanical Properties

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HYPERTENSION (2008)

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Review Peripheral Vascular Disease

Update on the use of antihypertensive drugs in pregnancy

Tiina Podymow et al.

HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Gender Differences in Regression of Electrocardiographic Left Ventricular Hypertrophy During Antihypertensive Therapy

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HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Day-by-Day Variability of Blood Pressure and Heart Rate at Home as a Novel Predictor of Prognosis The Ohasama Study

Masahiro Kikuya et al.

HYPERTENSION (2008)

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Review Peripheral Vascular Disease

Increase in carotid intima-media thickness in grade I hypertensive subjects - White-coat versus sustained hypertension

Massimo Puato et al.

HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Effects of Losartan in women with hypertension and left ventricular hypertrophy results from the Losartan Intervention For Endpoint Reduction in hypertension study

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HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Weight loss and blood pressure control (Pro)

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HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Gender differences in left ventricular structure and function during antihypertensive treatment - The Losartan intervention for Endpoint reduction in hypertension study

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HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Orthostatic Hypertension Detected by Self-Measured Home Blood Pressure Monitoring: A New Cardiovascular Risk Factor for Elderly Hypertensives

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HYPERTENSION RESEARCH (2008)

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Article Medicine, General & Internal

Ankle Brachial Index Combined With Framingham Risk Score to Predict Cardiovascular Events and Mortality

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)

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Review Peripheral Vascular Disease

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William J. Elliott

JOURNAL OF CLINICAL HYPERTENSION (2008)

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Editorial Material Peripheral Vascular Disease

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JOURNAL OF CLINICAL HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Hypertensive Urgencies in the Emergency Department: Evaluating Blood Pressure Response to Rest and to Antihypertensive Drugs With Different Profiles

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JOURNAL OF CLINICAL HYPERTENSION (2008)

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Pharmacological interventions for hypertensive emergencies: a Cochrane systematic review

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JOURNAL OF HUMAN HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Discontinuation of and changes in drug therapy for hypertension among newly-treated patients: a population-based study in Italy

Giovanni Corrao et al.

JOURNAL OF HYPERTENSION (2008)

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Article Peripheral Vascular Disease

Comparison between angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on the risk of myocardial infarction, stroke and death: a meta-analysis

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JOURNAL OF HYPERTENSION (2008)

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Article Geriatrics & Gerontology

The IANA task force on frailty assessment of older people in clinical practice

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JOURNAL OF NUTRITION HEALTH & AGING (2008)

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Article Cardiac & Cardiovascular Systems

Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore longitudinal study of aging

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JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)

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Article Urology & Nephrology

Effects of dietary sodium and hydrochlorothiazide on the antiproteinuric efficacy of losartan

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JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

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Article Medicine, General & Internal

Effects of extended-release metoprolol succinate inpatients undergoing non-cardiac surgery (POISE trial):: a randomised controlled trial

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LANCET (2008)

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Article Oncology

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LANCET ONCOLOGY (2008)

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Letter Medicine, General & Internal

Home blood-pressure monitoring in patients receiving sunitinib

Michel Azizi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Medicine, General & Internal

Telmisartan, ramipril, or both in patients at high risk for vascular events

Salim Yusuf et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Medicine, General & Internal

Treatment of hypertension in patients 80 years of age or older

Nigel S. Beckett et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Medicine, General & Internal

Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis

Anne B. Rossebo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Medicine, General & Internal

VEGF inhibition and renal thrombotic microangiopathy

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NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Medicine, General & Internal

Benazepril plus Amlodipine or Hydrochlorothiazide for Hypertension in High-Risk Patients

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NEW ENGLAND JOURNAL OF MEDICINE (2008)

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Article Multidisciplinary Sciences

The Efficacy of Pharmacotherapy for Decreasing the Expansion Rate of Abdominal Aortic Aneurysms: A Systematic Review and Meta-Analysis

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PLOS ONE (2008)

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Review Cardiac & Cardiovascular Systems

The blood pressure response to dynamic exercise testing: A systematic review

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PROGRESS IN CARDIOVASCULAR DISEASES (2008)

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Review Rheumatology

Hypertension in rheumatoid arthritis

V. F. Panoulas et al.

RHEUMATOLOGY (2008)

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Editorial Material Medicine, General & Internal

Assessment of proteinuria in pregnancy -: Urinary spot protein:creatinine ratio can reliably rule out proteinuria in pregnancy

Lucy C. Chappell et al.

BRITISH MEDICAL JOURNAL (2008)

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Editorial Material Medicine, General & Internal

GRADE:: what is quality of evidence and why is it important to clinicians?

Gordon H. Guyatt et al.

BMJ-BRITISH MEDICAL JOURNAL (2008)

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Article Medicine, General & Internal

Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger people: meta-analysis of randomised trials

F. Turnbull et al.

BMJ-BRITISH MEDICAL JOURNAL (2008)

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Article Medicine, General & Internal

Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories

Bernard Vrijens et al.

BMJ-BRITISH MEDICAL JOURNAL (2008)

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Article Cardiac & Cardiovascular Systems

Impact of resting heart rate on outcomes in hypertensive patients with coronary artery disease: findings from the INternational VErapamil-SR/trandolapril STudy (INVEST)

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EUROPEAN HEART JOURNAL (2008)

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Article Peripheral Vascular Disease

Prevalence and incidence of the metabolic syndrome in the European Lacidipine Study on Atherosclerosis (ELSA) and its relation with carotid intima-media thickness

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JOURNAL OF HYPERTENSION (2007)

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Review Immunology

Stress and inflammation in exacerbations of asthma

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BRAIN BEHAVIOR AND IMMUNITY (2007)

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Article Medicine, General & Internal

Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial

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LANCET (2007)

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Article Cardiac & Cardiovascular Systems

Candesartan in the prevention of relapsing atrial fibrillation

Arnljot Tveit et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2007)

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Article Peripheral Vascular Disease

Blood pressure control and improved cardiovascular outcomes in the international verapamil SR-trandolapril study

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HYPERTENSION (2007)

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Review Clinical Neurology

Silent brain infarcts: a systematic review

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LANCET NEUROLOGY (2007)

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Article Peripheral Vascular Disease

Long-term prognostic value of blood pressure variability in the general population - Results of the Pressioni Arteriose Monitorate e Loro Associazioni Study

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HYPERTENSION (2007)

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Review Peripheral Vascular Disease

2007 guidelines for the management of arterial hypertension

Giuseppe Mancia et al.

JOURNAL OF HYPERTENSION (2007)

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Article Urology & Nephrology

Pregnancy in CKD stages 3 to 5: Fetal and maternal outcomes

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AMERICAN JOURNAL OF KIDNEY DISEASES (2007)

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Article Peripheral Vascular Disease

Ambulatory arterial stiffness index is not a specific marker of reduced arterial compliance

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HYPERTENSION (2007)

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Article Peripheral Vascular Disease

Assessment of long-term antihypertensive treatment by clinic and ambulatory blood pressure: data from the European Lacidipine Study on Atherosclerosis

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JOURNAL OF HYPERTENSION (2007)

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Article Peripheral Vascular Disease

Direct renin inhibition with aliskiren in obese patients with arterial hypertension

Jens Jordan et al.

HYPERTENSION (2007)

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Article Pharmacology & Pharmacy

Visits in patients with asthma and chronic obstructive pulmonary disease taking β-blockers

Tyson W. A. Brooks et al.

PHARMACOTHERAPY (2007)

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Article Medicine, General & Internal

Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)

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BMJ-BRITISH MEDICAL JOURNAL (2007)

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Article Cardiac & Cardiovascular Systems

Effect of hypertension on anticoagulated patients with atrial fibrillation

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EUROPEAN HEART JOURNAL (2007)

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Review Medicine, General & Internal

The eye in hypertension

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LANCET (2007)

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Article Peripheral Vascular Disease

Hyperuricemia and incidence of hypertension among men without metabolic syndrome

Eswar Krishnan et al.

HYPERTENSION (2007)

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Article Peripheral Vascular Disease

Left atrial size and risk of major cardiovascular events during antihypertensive treatment -: Losartan intervention for endpoint reduction in hypertension trial

Eva Gerdts et al.

HYPERTENSION (2007)

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Review Urology & Nephrology

Anti hypertensive therapy in the presence of proteinuria

Pantelis A. Sarafidis et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2007)

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Article Peripheral Vascular Disease

Neurogenic abnormalities in masked hypertension

Guido Grassi et al.

HYPERTENSION (2007)

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Article Peripheral Vascular Disease

Reproducibility of dipping/nondipping pattern in untreated essential hypertensive patients: impact of sex and age

Cesare Cuspidi et al.

BLOOD PRESSURE MONITORING (2007)

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Review Urology & Nephrology

Beta blockers in the management of chronic kidney disease

G. L. Bakris et al.

KIDNEY INTERNATIONAL (2006)

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Article Peripheral Vascular Disease

Ethnic disparities in the incidence, presentation and complications of malignant hypertension

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JOURNAL OF HYPERTENSION (2006)

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Review Cardiac & Cardiovascular Systems

Expert consensus document on arterial stiffness: methodological issues and clinical applications

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EUROPEAN HEART JOURNAL (2006)

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Article Medicine, General & Internal

Regression of electrocardiographic left ventricular hypertrophy and decreased incidence of new-onset atrial fibrillation in patients with hypertension

Peter M. Okin et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)

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Article Urology & Nephrology

Selective aldosterone blockade with eplerenone reduces albuminuria in patients with type 2 diabetes

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CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

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Article Medicine, General & Internal

Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study

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LANCET (2006)

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Article Peripheral Vascular Disease

Thiazide diuretics, potassium, and the development of diabetes - A quantitative review

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HYPERTENSION (2006)

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Article Peripheral Vascular Disease

Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives

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HYPERTENSION (2006)

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Article Cardiac & Cardiovascular Systems

Prevention of atrial fibrillation in patients with symptomatic chronic heart failure by candesartan in the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) program

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AMERICAN HEART JOURNAL (2006)

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Article Medicine, General & Internal

Dogma disputed: Can aggressively hypertensive patients with coronary artery lowering blood pressure in disease be dangerous?

Franz H. Messerli et al.

ANNALS OF INTERNAL MEDICINE (2006)

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Review Medicine, General & Internal

Medical progress - Assessing kidney function - Measured and estimated glomerular filtration rate

Lesley A. Stevens et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

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Article Peripheral Vascular Disease

Long-term risk of mortality associated with selective and combined elevation in office, home, and ambulatory blood pressure

G Mancia et al.

HYPERTENSION (2006)

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Article Medicine, General & Internal

Feasibility of treating prehypertension with an angiotensin-receptor blocker

S Julius et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

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Article Peripheral Vascular Disease

Therapeutic inertia is an impediment to achieving the healthy people 2010 blood pressure control goals

EC Okonofua et al.

HYPERTENSION (2006)

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Article Medicine, General & Internal

Efficacy and safety of benazepril for advanced chronic renal insufficiency

FF Hou et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

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Article Medicine, General & Internal

International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis

DL Bhatt et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)

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Article Peripheral Vascular Disease

Lower target blood pressures are safe and effective for the prevention of recurrent stroke: the PROGRESS trial

Hisatomi Arima et al.

JOURNAL OF HYPERTENSION (2006)

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Article Peripheral Vascular Disease

The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients

LS Liu et al.

JOURNAL OF HYPERTENSION (2005)

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Article Surgery

Improved long-term outcomes after renal transplantation associated with blood pressure control

G Opelz et al.

AMERICAN JOURNAL OF TRANSPLANTATION (2005)

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Article Urology & Nephrology

Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the Irbesartan Diabetic Nephropathy Trial: Clinical implications and limitations

MA Pohl et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)

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Article Peripheral Vascular Disease

Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors

VA Cornelissen et al.

HYPERTENSION (2005)

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Article Medicine, General & Internal

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA):: a multicentre randomised controlled trial

B Dahlöf et al.

LANCET (2005)

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Article Medicine, General & Internal

A global clinical measure of fitness and frailty in elderly people

K Rockwood et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2005)

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Article Peripheral Vascular Disease

Increased stroke volume and aortic stiffness contribute to isolated systolic hypertension in young adults

CM McEniery et al.

HYPERTENSION (2005)

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Article Urology & Nephrology

Atherosclerotic renovascular disease in United States patients aged 67 years or older: Risk factors, revascularization, and prognosis

PA Kalra et al.

KIDNEY INTERNATIONAL (2005)

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Review Critical Care Medicine

The relationship between reduced lung function and cardiovascular mortality - A population-based study and a systematic review of the literature

DD Sin et al.

CHEST (2005)

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Article Peripheral Vascular Disease

Relationship of office, home, and ambulatory blood pressure to blood glucose and lipid variables in the PAMELA population

G Mancia et al.

HYPERTENSION (2005)

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Article Peripheral Vascular Disease

Stopping oral contraceptives: an effective blood pressure-lowering intervention in women with hypertension

JN Lubianca et al.

JOURNAL OF HUMAN HYPERTENSION (2005)

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Article Peripheral Vascular Disease

Baroreflex failure

K Heusser et al.

HYPERTENSION (2005)

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Article Medicine, General & Internal

The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease - Results of the African American study of kidney disease and hypertension

J Lea et al.

ARCHIVES OF INTERNAL MEDICINE (2005)

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Article Medicine, General & Internal

Renal outcomes in high-risk hypertensive patients treated with an angiotensin-converting enzyme inhibitor or a calcium channel blocker vs a diuretic - A report from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)

M Rahman et al.

ARCHIVES OF INTERNAL MEDICINE (2005)

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Article Cardiac & Cardiovascular Systems

Prognostic value of ambulatory and home blood pressures compared with office blood pressure in the general population - Follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study

R Sega et al.

CIRCULATION (2005)

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Article Medicine, General & Internal

Outcomes in hypertensive black and nonblack patients treated with chlorthalidone, amlodipine, and lisinopril

JT Wright et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

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Article Cardiac & Cardiovascular Systems

Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol -: The Losartan Intervention For End point reduction in hypertension (LIFE) study

K Wachtell et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)

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Article Peripheral Vascular Disease

Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients -: Losartan intervention for endpoint reduction in hypertension study

H Ibsen et al.

HYPERTENSION (2005)

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Article Peripheral Vascular Disease

Left ventricular concentric geometry during treatment adversely affects cardiovascular prognosis in hypertensive patients

ML Muiesan et al.

HYPERTENSION (2004)

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Article Medicine, General & Internal

Cardiovascular prognosis of masked hypertension detected by blood pressure self-measurement in elderly treated hypertensive patients

G Bobrie et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

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Article Pediatrics

Home, clinic, and ambulatory blood pressure monitoring in children with chronic renal failure

E Wühl et al.

PEDIATRIC RESEARCH (2004)

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Article Urology & Nephrology

The impact of serum uric acid on cardiovascular outcomes in the LIFE study

A Hoieggen et al.

KIDNEY INTERNATIONAL (2004)

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Article Medicine, General & Internal

Randomised equivalence trial comparing three and six months of follow up of patients with hypertension by family practitioners

RV Birtwhistle et al.

BMJ-BRITISH MEDICAL JOURNAL (2004)

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Article Medicine, General & Internal

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

S Yusuf et al.

LANCET (2004)

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Article Peripheral Vascular Disease

Prevalence and clinical significance of isolated ambulatory hypertension in young subjects screened for stage 1 hypertension

P Palatini et al.

HYPERTENSION (2004)

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Article Medicine, General & Internal

Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery

L Sjöström et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

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Article Medicine, General & Internal

Prognostic significance of left ventricular mass change during treatment of hypertension

RB Devereux et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

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Article Medicine, General & Internal

Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events

PM Okin et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

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Article Pharmacology & Pharmacy

Effects of passive smoking on blood pressure and aortic pressure waveform in healthy young adults - influence of gender

A Mahmud et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)

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Review Pharmacology & Pharmacy

Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications

AA Mangoni et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2004)

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Article Medicine, General & Internal

Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension - A randomized controlled trial

GL Bakris et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

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Article Medicine, General & Internal

Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial

S Julius et al.

LANCET (2004)

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Article Medicine, General & Internal

Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial

MA Weber et al.

LANCET (2004)

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Article Medicine, General & Internal

Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy

AH Barnett et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

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Article Medicine, General & Internal

Preventing microalbuminuria in type 2 diabetes

P Ruggenenti et al.

NEW ENGLAND JOURNAL OF MEDICINE (2004)

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Article Peripheral Vascular Disease

Hypertension treatment and control in five European Countries, Canada, and the United States

K Wolf-Maier et al.

HYPERTENSION (2004)

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Article Peripheral Vascular Disease

Silent cerebral white matter lesions and cognitive function in middle-aged essential hypertensive patients

C Sierra et al.

AMERICAN JOURNAL OF HYPERTENSION (2004)

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Article Peripheral Vascular Disease

Blood pressure control and physician management of hypertension in hospital hypertension units in Spain

JR Banegas et al.

HYPERTENSION (2004)

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Article Peripheral Vascular Disease

Reasons for not intensifying anti hypertensive treatment (RIAT): a primary care anti hypertensive intervention study

P Ferrari et al.

JOURNAL OF HYPERTENSION (2004)

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Article Medicine, General & Internal

Effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists on mortality and renal outcomes in diabetic nephropathy: systematic review

GFM Strippoli et al.

BMJ-BRITISH MEDICAL JOURNAL (2004)

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Article Peripheral Vascular Disease

Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled

P Bramlage et al.

AMERICAN JOURNAL OF HYPERTENSION (2004)

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Article Medicine, General & Internal

A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease - The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial

CJ Pepine et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)

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Article Cardiac & Cardiovascular Systems

Prognostic significance of small-artery structure in hypertension

D Rizzoni et al.

CIRCULATION (2003)

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Article Peripheral Vascular Disease

Diuretic versus α-blocker as first-step antihypertensive therapy -: Final results from the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)

MH Alderman

HYPERTENSION (2003)

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Review Clinical Neurology

Risk factors for intracerebral hemorrhage in the general population - A systematic review

MJ Ariesen et al.

STROKE (2003)

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Article Medicine, General & Internal

Effects of blood pressure level on progression of diabetic nephropathy - Results from the RENAAL study

GL Bakris et al.

ARCHIVES OF INTERNAL MEDICINE (2003)

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Article Peripheral Vascular Disease

Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials

JM Geleijnse et al.

JOURNAL OF HUMAN HYPERTENSION (2003)

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Article Medicine, General & Internal

Prognostic value of ambulatory blood-pressure recordings in patients with treated hypertension

DL Clement et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

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Review Cardiac & Cardiovascular Systems

Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases

ME Safar et al.

CIRCULATION (2003)

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Article Cardiac & Cardiovascular Systems

Estimation of ten-year risk of fatal cardiovascular disease in Europe:: the SCORE project

RM Conroy et al.

EUROPEAN HEART JOURNAL (2003)

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Review Medicine, General & Internal

Health outcomes associated with various antihypertensive therapies used as first-line agents - A network meta-analysis

BN Psaty et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)

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Article Peripheral Vascular Disease

The Study on cognition and prognosis in the elderly (SCOPE): principal results of a randomized double-blind intervention trial

H Lithell et al.

JOURNAL OF HYPERTENSION (2003)

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Article Cardiac & Cardiovascular Systems

Framingham risk function overestimates risk of coronary heart disease in men and women from Germany -: results from the MONICA Augsburg and the PROCAM cohorts

HW Hense et al.

EUROPEAN HEART JOURNAL (2003)

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Article Medicine, General & Internal

Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) Trial

HR Black et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)

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Article Medicine, General & Internal

Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA):: a multicentre randomised controlled trial

PS Sever et al.

LANCET (2003)

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Article Emergency Medicine

Reproducibility of increased blood pressure during an emergency department or urgent care visit

HD Backer et al.

ANNALS OF EMERGENCY MEDICINE (2003)

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Article Cardiac & Cardiovascular Systems

Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives - A prospective study

K Kario et al.

CIRCULATION (2003)

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Article Peripheral Vascular Disease

The white-coat effect is unrelated to the difference between clinic and daytime blood pressure and is associated with greater reactivity to public speaking

P Palatini et al.

JOURNAL OF HYPERTENSION (2003)

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Article Peripheral Vascular Disease

Spurious systolic hypertension of youth: Fit young men with elastic arteries

A Mahmud et al.

AMERICAN JOURNAL OF HYPERTENSION (2003)

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Article Peripheral Vascular Disease

Neural control of the kidney - Past, present, and future

GF DiBona

HYPERTENSION (2003)

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Article Medicine, General & Internal

A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly

LMH Wing et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

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Letter Geriatrics & Gerontology

Resting heart rate in older people: A predictor of survival to age 85

A Benetos et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2003)

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Article Peripheral Vascular Disease

Influence of weight reduction on blood pressure - A meta-analysis of randomized controlled trials

JE Neter et al.

HYPERTENSION (2003)

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Article Cardiac & Cardiovascular Systems

Change of left ventricular geometric, pattern after 1 year of antihypertensive treatment:: The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study

K Wachtell et al.

AMERICAN HEART JOURNAL (2002)

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Article Medicine, General & Internal

Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease - Results from the AASK trial

JT Wright et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

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Article Peripheral Vascular Disease

Orlistat improves blood pressure control in obese subjects with treated but inadequately controlled hypertension

G Bakris et al.

JOURNAL OF HYPERTENSION (2002)

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Review Geriatrics & Gerontology

Identifying the elderly at risk for malnutrition - The Mini Nutritional Assessment

Y Guigoz et al.

CLINICS IN GERIATRIC MEDICINE (2002)

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Article Cardiac & Cardiovascular Systems

Sympathetic nerve activity in end-stage renal disease

M Hausberg et al.

CIRCULATION (2002)

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Article Medicine, General & Internal

Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes

E Lurbe et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)

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Article Peripheral Vascular Disease

Influence of age, sex and blood pressure on the principal endpoints of the Nordic Diltiazem (NORDIL) Study

SE Kjeldsen et al.

JOURNAL OF HYPERTENSION (2002)

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Article Medicine, General & Internal

Pulse pressure and cardiovascular disease-related mortality - Follow-up study of the Multiple Risk Factor Intervention Trial (MRFIT)

M Domanski et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

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Article Medicine, General & Internal

Effect of aerobic exercise on blood pressure: A meta-analysis of randomized, controlled trials

SP Whelton et al.

ANNALS OF INTERNAL MEDICINE (2002)

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Article Clinical Neurology

Occurrence of secondary ischemic events among persons with atherosclerotic vascular disease

BG Vickrey et al.

STROKE (2002)

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Article Medicine, General & Internal

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE):: a randomised trial against atenolol

B Dahlöf et al.

LANCET (2002)

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Article Cardiac & Cardiovascular Systems

Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period

A Benetos et al.

CIRCULATION (2002)

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Article Medicine, General & Internal

Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

WC Knowler et al.

NEW ENGLAND JOURNAL OF MEDICINE (2002)

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Article Peripheral Vascular Disease

Reproducibility of home, ambulatory, and clinic blood pressure: Implications for the design of trials for the assessment of antihypertensive drug efficacy

GS Stergiou et al.

AMERICAN JOURNAL OF HYPERTENSION (2002)

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Article Peripheral Vascular Disease

Blood pressure variability and organ damage in a general population - Results from the PAMELA study

R Sega et al.

HYPERTENSION (2002)

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Article Peripheral Vascular Disease

Correlates of left atrial size in hypertensive patients with left ventricular hypertrophy - The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study

E Gerdts et al.

HYPERTENSION (2002)

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Article Medicine, General & Internal

Clinical inertia

LS Phillips et al.

ANNALS OF INTERNAL MEDICINE (2001)

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Correction Medicine, General & Internal

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack (Vol 358, pg 1033, 2001)

LANCET (2001)

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Article Peripheral Vascular Disease

High prevalence of cardiac and extracardiac target organ damage in refractory hypertension

C Cuspidi et al.

JOURNAL OF HYPERTENSION (2001)

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Article Medicine, General & Internal

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack

S MacMahon et al.

LANCET (2001)

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Article Medicine, General & Internal

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

BM Brenner et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Article Medicine, General & Internal

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

EJ Lewis et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Article Cardiac & Cardiovascular Systems

Alterations of cardiac structure in patients with isolated office, ambulatory, or home hypertension - Data from the general population (Pressione Arteriose Monitorate E Loro Associazioni [PAMELA] Study)

R Sega et al.

CIRCULATION (2001)

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Article Medicine, General & Internal

Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals

HC Gerstein et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)

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Article Rheumatology

Cardiovascular risk factors, including thrombotic variables, in a population with rheumatoid arthritis

A McEntegart et al.

RHEUMATOLOGY (2001)

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Article Urology & Nephrology

A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy

JP Kooman et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2001)

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Review Peripheral Vascular Disease

Gender differences in the regulation of blood pressure

JF Reckelhoff

HYPERTENSION (2001)

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Article Peripheral Vascular Disease

Insulin-mediated sympathetic stimulation: role in the pathogenesis of obesity-related hypertension (or, how insulin affects blood pressure, and why)

L Landsberg

JOURNAL OF HYPERTENSION (2001)

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Article Peripheral Vascular Disease

Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives - Analysis based on National Health and Nutrition Examination Survey (NHANES) III

SS Franklin et al.

HYPERTENSION (2001)

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Review Medicine, General & Internal

Medical progress - Renal-artery stenosis

RD Safian et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Article Peripheral Vascular Disease

β-Adrenergic receptor blockers and weight gain -: A systematic analysis

AM Sharma et al.

HYPERTENSION (2001)

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Article Medicine, General & Internal

Effects on blood pressure of reduced dietary sodium and the dietary approaches to stop hypertension (DASH) diet.

FM Sacks et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

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Article Medicine, General & Internal

Long-term weight loss and changes in blood pressure: Results of the trials of hypertension prevention, phase II

VJ Stevens et al.

ANNALS OF INTERNAL MEDICINE (2001)

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Article Peripheral Vascular Disease

Patterns of hypertension management in Italy: results of a pharmacoepidemiological survey on antihypertensive therapy

E Ambrosioni et al.

JOURNAL OF HYPERTENSION (2000)

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Article Peripheral Vascular Disease

Adrenergic and reflex abnormalities in obesity-related hypertension

G Grassi et al.

HYPERTENSION (2000)

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Article Medicine, General & Internal

Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study

AI Adler et al.

BMJ-BRITISH MEDICAL JOURNAL (2000)

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Article Medicine, General & Internal

Randomised trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension:: the Nordic Diltiazem (NORDIL) study

L Hansson et al.

LANCET (2000)

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Review Medicine, General & Internal

Hypertensive emergencies

CJ Vaughan et al.

LANCET (2000)

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Article Medicine, General & Internal

Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke - The Systolic Hypertension in the Elderly Program (SHEP)

HM Perry et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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Article Multidisciplinary Sciences

Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy

DS Geller et al.

SCIENCE (2000)

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Review Medicine, General & Internal

Ischemic stroke risk with oral contraceptives - A meta-analysis

LA Gillum et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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Article Peripheral Vascular Disease

Practice vs ambulatory blood pressure measurement under treatment with ramipril (PLUR Study):: a randomised, prospective long-term study to evaluate the benefits of ABPM in patients on antihypertensive treatment

J Schrader et al.

JOURNAL OF HUMAN HYPERTENSION (2000)

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Article Medicine, General & Internal

Chinese trial on isolated systolic hypertension in the elderly

JG Wang et al.

ARCHIVES OF INTERNAL MEDICINE (2000)

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Article Medicine, General & Internal

Primary care outcomes in patients treated by nurse practitioners or physicians - A randomized trial

MO Mundinger et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)

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Article Cardiac & Cardiovascular Systems

Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance

NG Bellenger et al.

JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2000)

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Article Cardiac & Cardiovascular Systems

Comparison of the Framingham risk function-based coronary chart with risk function from an Italian population study

A Menotti et al.

EUROPEAN HEART JOURNAL (2000)

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