期刊
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
卷 127, 期 2, 页码 1751-1756出版社
SPRINGER
DOI: 10.1007/s10973-016-5551-2
关键词
Cinnarizine; Isothermal; Non-isothermal; Kinetics
Cinnarizine (CIN) is an anti-histaminic drug which is mainly used for the control of vomiting due to motion sickness. The thermal behavior of CIN was investigated using thermogravimetry/derivative thermogravimetry and differential thermal analysis. The kinetic parameters were evaluated by isothermal and non-isothermal conditions including Ozawa's conventional method, Ozawa-Flynn-Wall and Friedman isoconversional methods. The kinetic parameters were determined using the thermogravimetric curves of the decomposition process. The activation energy values obtained were 88.38 and 90.12 kJ mol(-1) for the isothermal and non-isothermal conditions, respectively, with the conventional method. The activation energy values obtained by isoconversional method were practically equal; hence, the reaction involves a single step. Finally, the values of entropy (a dagger S), enthalpy (a dagger H), and Gibbs free energy change (a dagger G) of decomposition reaction were calculated and compared.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据