☆ 4.7 Article

Depleting CD103+ resident memory T cells in vivo reveals immunostimulatory functions in oral mucosa

JOURNAL OF EXPERIMENTAL MEDICINE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Immunology

Small intestine and colon tissue-resident memory CD8+T cells exhibit molecular heterogeneity and differential dependence on Eomes

Yun Hsuan Lin et al.

Summary: Tissue-resident memory CD8+ T (TRM) cells are a subset of memory T cells that are important for controlling infection. TRM cells in the small intestine and colon exhibit heterogeneity in terms of cytokine and granzyme expression, transcriptional and epigenetic regulation, and functional characteristics. The transcription factor Eomes plays a context-specific role in supporting the maintenance of established TRM cells in the small intestine but not in the colon.

IMMUNITY (2023)

添加到收藏夹

Article Cell Biology

Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface

Joon Keit Loi et al.

Summary: This study used intravital microscopy to investigate T cell responses in the cornea and identified the presence of tissue-resident memory T (T-RM) cells, which can provide local protective immunity.

CELL REPORTS (2022)

添加到收藏夹

Article Immunology

Tissue-resident memory CD8(+) T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments

John T. Crowl et al.

Summary: This study investigates the diversity of gene expression and genome accessibility in mouse CD8(+) T-RM cells in different tissues, and identifies molecules critical for the generation of CD8(+) T-RM cells in response to acute viral infection. The research reveals both common and tissue-specific transcriptional and epigenetic signatures in T-RM cells from different organs. T-RM cells in the intestine and salivary glands express TGF-beta-induced genes and are maintained by ongoing TGF-beta signaling, while those in the fat, kidney, and liver do not. Furthermore, the study identifies the transcriptional repressor Hic1 as a critical regulator of T-RM cell differentiation in the small intestine, and shows that Hic1 overexpression enhances T-RM cell differentiation and protection from infection.

NATURE IMMUNOLOGY (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Pyroptosis-Mediated Periodontal Disease

Mariane Beatriz Sordi et al.

Summary: Pyroptosis is a pathological mechanism in the cause of periodontitis, involving caspase activation, cleavage of gasdermin D, and secretion of interleukins to induce tissue destruction. Removing periopathogens' virulence factors that trigger pyroptosis may be a potential strategy to combat periodontal disease.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Immunology

Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium

John P. Shannon et al.

Summary: The oropharyngeal mucosa serves as a primary site for pathogen entry and viral replication. During acute oral mucosal viral infection, ILC1s play a crucial role in providing early protection through IFN-γ production, enhancing resistance against oral mucosal viruses.

IMMUNITY (2021)

添加到收藏夹

Review Medicine, General & Internal

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

Giusy Rita Maria La Rosa et al.

Summary: Oral lesions associated with COVID-19 have diverse etiopathogenesis including ulcerations, aphthous-like lesions, and macules, predominantly found on the tongue, lips, and palate. These lesions in COVID-19 patients may be underestimated, potentially linked to the direct or indirect action of SARS-CoV-2, coinfections, immune impairment, and drug reactions. Further research is needed to establish the diagnostic and pathological significance of oral manifestations of COVID-19.

FRONTIERS IN MEDICINE (2021)

添加到收藏夹

Review Immunology

CD8+ T Lymphocytes: Crucial Players in Sjogren's Syndrome

Huimin Zhou et al.

Summary: Primary Sjogren's syndrome (pSS) is a chronic autoimmune disease characterized by damage to multiple organs and glands, with dry eyes, dry mouth, and enlarged salivary glands being common clinical manifestations. CD8(+) T lymphocytes have been found to play a significant role in acinar injury in the exocrine glands, contributing to the pathophysiology of the disease. Targeting CD8(+) T cells in treatment strategies can offer promising new approaches for managing pSS.

FRONTIERS IN IMMUNOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Expansible residence decentralizes immune homeostasis

Sathi Wijeyesinghe et al.

Summary: The immune system in adult mice is integrated within tissues, with a durable maintenance of resident memory T cells contributing to tissue immunity. Tissue pliancy facilitates the accumulation of tissue-resident memory without eroding pre-existing antiviral T cell immunity, resulting in the decentralized homeostasis of organismal immunity.

NATURE (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

SARS-CoV-2 infection of the oral cavity and saliva

Ni Huang et al.

Summary: The study highlights the potential role of the oral cavity in COVID-19 pathogenesis, with evidence of SARS-CoV-2 infection and transmission via saliva. Viral shedding dynamics in saliva correlated with symptoms, and asymptomatic individuals were found to harbor sustained salivary antibodies against SARS-CoV-2 post-recovery.

NATURE MEDICINE (2021)

添加到收藏夹

Review Immunology

Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

George Hajishengallis et al.

Summary: Periodontitis is causally linked to the development of other chronic inflammatory diseases outside the oral mucosa, and intervention studies have shown that local treatment of periodontitis can ameliorate surrogate markers of comorbid conditions. Experimental animal studies have further strengthened the potential causal link by establishing biologically plausible and clinically consistent mechanisms. Understanding the impact of disseminated periodontal pathogens and systemic inflammation associated with periodontitis on extra-oral pathologies may lead to new therapeutic options to reduce the risk of periodontitis-associated comorbidities.

NATURE REVIEWS IMMUNOLOGY (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Resident memory T cells: Possible players in periodontal disease recurrence

Federico Deli et al.

JOURNAL OF PERIODONTAL RESEARCH (2020)

添加到收藏夹

Review Immunology

Regulation of host-microbe interactions at oral mucosal barriers by type 17 immunity

Sarah L. Gaffen et al.

SCIENCE IMMUNOLOGY (2020)

添加到收藏夹

Article Immunology

Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

J. Justin Milner et al.

IMMUNITY (2020)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy

George Hajishengallis et al.

PERIODONTOLOGY 2000 (2020)

添加到收藏夹

Review Primary Health Care

Viral infections of oral cavity

Arvind Babu Rajendra Santosh et al.

JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE (2020)

添加到收藏夹

Article Immunology

Tissue-Resident T Cells and Other Resident Leukocytes

David Masopust et al.

Annual Review of Immunology (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

Pamela C. Rosato et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

Tom Dudding et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Behavioral Sciences

Mammalian Taste Cells Express Functional Olfactory Receptors

Bilal Malik et al.

CHEMICAL SENSES (2019)

添加到收藏夹

Article Immunology

Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells

Toshiro Hirai et al.

IMMUNITY (2019)

添加到收藏夹

Review Immunology

The Role of Memory CD8+ T Cells in Vitiligo

Rebecca L. Riding et al.

JOURNAL OF IMMUNOLOGY (2019)

添加到收藏夹

Review Immunology

Location, location, location: Tissue resident memory T cells in mice and humans

Peter A. Szabo et al.

SCIENCE IMMUNOLOGY (2019)

添加到收藏夹

Article Cell Biology

The human tissue-resident CCR5+ T cell compartment maintains protective and functional properties during inflammation

Amanda S. Woodward Davis et al.

SCIENCE TRANSLATIONAL MEDICINE (2019)

添加到收藏夹

Review Immunology

Tissue-Specific Immunity at the Oral Mucosal Barrier

Niki M. Moutsopoulos et al.

TRENDS IN IMMUNOLOGY (2018)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Matrix Metalloproteinase-8 as an Inflammatory and Prevention Biomarker in Periodontal and Peri-Implant Diseases

Ahmed Al-Majid et al.

INTERNATIONAL JOURNAL OF DENTISTRY (2018)

添加到收藏夹

Article Immunology

TRM maintenance is regulated by tissue damage via P2RX7

Regina Stark et al.

SCIENCE IMMUNOLOGY (2018)

添加到收藏夹

Article Genetics & Heredity

Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I

Fu Xiong et al.

HUMAN MUTATION (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Matrix Metalloproteinases as Regulators of Periodontal Inflammation

Cavalla Franco et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

添加到收藏夹

Article Virology

Stress Hormones Epinephrine and Corticosterone Selectively Modulate Herpes Simplex Virus 1 (HSV-1) and HSV-2 Productive Infections in Adult Sympathetic, but Not Sensory, Neurons

Angela M. Ives et al.

JOURNAL OF VIROLOGY (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

Youdong Pan et al.

NATURE (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Multiplex, quantitative cellular analysis in large tissue volumes with clearing-enhanced 3D microscopy (Ce3D)

Weizhe Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

添加到收藏夹

Article Immunology

Discriminating between Interstitial and Circulating Leukocytes in Tissues of the Murine Oral Mucosa Avoiding Nasal-Associated Lymphoid Tissue Contamination

Peter D. Bittner-Eddy et al.

FRONTIERS IN IMMUNOLOGY (2017)

添加到收藏夹

Article Immunology

CD8+ T Cells in Chronic periodontitis: Roles and Rules

Elsa M. Cardoso et al.

FRONTIERS IN IMMUNOLOGY (2017)

添加到收藏夹

Article Immunology

Resident memory T cells in the skin mediate durable immunity to melanoma

Brian T. Malik et al.

SCIENCE IMMUNOLOGY (2017)

添加到收藏夹

Article Immunology

Characterization of the human immune cell network at the gingival barrier

N. Dutzan et al.

MUCOSAL IMMUNOLOGY (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Normalizing the environment recapitulates adult human immune traits in laboratory mice

Lalit K. Beura et al.

NATURE (2016)

添加到收藏夹

Review Immunology

Tissue-resident memory T cells: local specialists in immune defence

Scott N. Mueller et al.

NATURE REVIEWS IMMUNOLOGY (2016)

添加到收藏夹

Article Medicine, Research & Experimental

Vaccine-generated lung tissue-resident memory T cells provide heterosubtypic protection to influenza infection

Kyra D. Zens et al.

JCI INSIGHT (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

Elizabeth M. Steinert et al.

CELL (2015)

添加到收藏夹

Article Immunology

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells

Heather D. Hickman et al.

IMMUNITY (2015)

添加到收藏夹

Article Cell Biology

Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells

Rei Watanabe et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

添加到收藏夹

Review Cell Biology

Resident memory T cells in human health and disease

Rachael A. Clark

SCIENCE TRANSLATIONAL MEDICINE (2015)

添加到收藏夹

Article Oncology

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

Jacques Ferlay et al.

INTERNATIONAL JOURNAL OF CANCER (2015)

添加到收藏夹

Article Immunology

Lung niches for the generation and maintenance of tissue-resident memory T cells

D. L. Turner et al.

MUCOSAL IMMUNOLOGY (2014)

添加到收藏夹

Article Biochemical Research Methods

Intravascular staining for discrimination of vascular and tissue leukocytes

Kristin G. Anderson et al.

NATURE PROTOCOLS (2014)

添加到收藏夹

Review Dentistry, Oral Surgery & Medicine

Inflammatory and immune pathways in the pathogenesis of periodontal disease

Ali Cekici et al.

PERIODONTOLOGY 2000 (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

Jason M. Schenkel et al.

SCIENCE (2014)

添加到收藏夹

Article Multidisciplinary Sciences

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

Silvia Ariotti et al.

SCIENCE (2014)

添加到收藏夹

Article Immunology

Transforming Growth Factor-β Signaling Controls the Formation and Maintenance of Gut-Resident Memory T Cells by Regulating Migration and Retention

Nu Zhang et al.

IMMUNITY (2013)

添加到收藏夹

Article Immunology

Sensing and alarm function of resident memory CD8+ T cells

Jason M. Schenkel et al.

NATURE IMMUNOLOGY (2013)

添加到收藏夹

Article Immunology

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

Laura K. Mackay et al.

NATURE IMMUNOLOGY (2013)

添加到收藏夹

Review Oncology

Inflammation in the context of oral cancer

L. Feller et al.

ORAL ONCOLOGY (2013)

添加到收藏夹

Article Microbiology

Herpesviruses: latency and reactivation – viral strategies and host response

Bjørn Grinde

Journal of Oral Microbiology (2013)

添加到收藏夹

Article Allergy

Antigen-specific effector CD8 T cells regulate allergic responses via IFN-γ and dendritic cell function

Yafang Tang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

添加到收藏夹

Review Immunology

The T cell in Sjogren's syndrome: Force majeure, not spectateur

Namrata Singh et al.

JOURNAL OF AUTOIMMUNITY (2012)

添加到收藏夹

Article Immunology

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

Kerry A. Casey et al.

JOURNAL OF IMMUNOLOGY (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

Xiaodong Jiang et al.

NATURE (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower et al.

NATURE (2012)

添加到收藏夹

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

添加到收藏夹

Article Multidisciplinary Sciences

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

Laura K. Mackay et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

添加到收藏夹

Article Immunology

Expression of Th1/Th2/Th3/Th17-Related Genes in Recurrent Aphthous Ulcers

Natalia Lewkowicz et al.

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2011)

添加到收藏夹

Article Biochemical Research Methods

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson et al.

BIOINFORMATICS (2010)

添加到收藏夹

Article Microbiology

The Human Oral Microbiome

Floyd E. Dewhirst et al.

JOURNAL OF BACTERIOLOGY (2010)

添加到收藏夹

Article Immunology

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

Heather D. Hickman et al.

NATURE IMMUNOLOGY (2008)

添加到收藏夹

Article Immunology

The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics

Levi G. Ledgerwood et al.

NATURE IMMUNOLOGY (2008)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Gingival crevicular fluid matrix metalloproteinase-25 and-26 levels in periodontal disease

Gulnur Emingil et al.

JOURNAL OF PERIODONTOLOGY (2006)

添加到收藏夹

Article Immunology

Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor β II receptor

PJ Lucas et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.