☆ 4.5 Article

Selective targeting of gold nanoparticles for radiosensitization of somatostatin 2 receptor-expressing cancer cells

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Spectroscopy

Citrate functionalized gold nanoparticles assisted micro extraction of L-cysteine in milk and water samples using Fourier transform infrared spectroscopy

Beeta Rani Khalkho et al.

Summary: The sensing application of citrate-functionalized gold nanoparticles (AuNPs) for the determination of L-cysteine in food and water samples was successfully demonstrated in this study. The aggregation of AuNPs enhanced the signal intensity of L-cysteine, resulting in effective absorption of electromagnetic radiation in the IR region for molecular vibration. The theoretical investigation and experimental results confirmed the interaction between AuNPs and L-cysteine molecules, leading to a shift in plasmon bands and aggregation of particles.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

添加到收藏夹

Article Oncology

Somatostatin Receptor 2 Expression Profiles and Their Correlation with the Efficacy of Somatostatin Analogues in Gastrointestinal Neuroendocrine Tumors

Hirofumiip Watanabe et al.

Summary: This study evaluated the significance of SSTR2 immunoreactivity in gastrointestinal neuroendocrine tumors (GI-NETs) using digital image analysis (DIA) and other methods. The results showed that SSTR2 immunoreactivity varied according to the primary sites and was correlated with proliferative activity. Additionally, DIA was found to be a good alternative for predicting response to somatostatin analogues (SSAs) in evaluating SSTR2 immunoreactivity of GI-NETs.

CANCERS (2022)

添加到收藏夹

Article Biophysics

GMT8 aptamer conjugated PEGylated Ag@Au core-shell nanoparticles as a novel radiosensitizer for targeted radiotherapy of glioma

Dongdong Li et al.

Summary: This study developed polyethylene glycol-coated Ag@Au core-shell nanoparticles (PSGNPs) modified with GMT8 aptamer (GSGNPs) and evaluated their radiosensitization effects on glioma cells through in vivo and in vitro experiments. The results demonstrated that GSGNPs showed good targeting ability, enhanced sensitization effect, and prolonged median survival time of mice bearing U87 glioma after intravenous administration combined with radiotherapy.

COLLOIDS AND SURFACES B-BIOINTERFACES (2022)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Promoting reactive oxygen species generation: a key strategy in nanosensitizer-mediated radiotherapy

Shichong Jia et al.

Summary: The radiotherapy enhancement effect of numerous nanosensitizers is based on the excessive production of reactive oxygen species (ROS). Understanding the role of ROS in radiosensitization is necessary, as it has double-edged sword effects and potential dangers. Future perspectives regarding ROS-regulated nanosensitizer applications and development need to be discussed.

NANOMEDICINE (2021)

添加到收藏夹

Review Endocrinology & Metabolism

Role of Somatostatin Receptor in Pancreatic Neuroendocrine Tumor Development, Diagnosis, and Therapy

Yuheng Hu et al.

Summary: SSTRs have significant clinical significance in pNETs, serving as important targets for diagnosis and treatment, but further research is needed.

FRONTIERS IN ENDOCRINOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival

Aristides D. Tagalakis et al.

Summary: This study introduces a novel formulation of siRNA nanoparticles, termed RTNs, which can target tumors effectively while minimizing clearance by the liver, resulting in predominant accumulation in tumors rather than other organs in the body. The experiment demonstrates that these siRNA nanoparticles significantly retard the growth of xenograft tumors and improve survival rates, showing promise for delivering targeted siRNA therapeutics for cancer treatment.

ADVANCED FUNCTIONAL MATERIALS (2021)

添加到收藏夹

Review Oncology

Nanomaterials for cancer therapy: current progress and perspectives

Zhe Cheng et al.

Summary: Nanomaterials play an important role in cancer therapy by targeting cancer cells, tumor microenvironment, and the immune system. However, despite an increasing number of studies, the approval of nano-drugs has not significantly increased, requiring further research to improve clinical translation efficiency.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Polyethylene Glycol Functionalized Graphene Oxide Nanoparticles Loaded with Nigella sativa Extract: A Smart Antibacterial Therapeutic Drug Delivery System

Mustafa A. Jihad et al.

Summary: The study focused on synthesizing graphene oxide nanoparticles, capping them with polyethylene glycol, and loading them with Nigella sativa seed extract to create a potential smart drug delivery system. The GO-PEG NPs were characterized structurally using various methods and were found to effectively destroy bacteria by permeating their membranes and damaging their nucleic acids.

MOLECULES (2021)

添加到收藏夹

Review Chemistry, Medicinal

Surface receptor-mediated targeted drug delivery systems for enhanced cancer treatment: A state-of-the-art review

Selvaraj Kunjiappan et al.

Summary: Enhanced cancer treatment is a key focus for researchers globally, with challenges and opportunities in developing interdisciplinary approaches to alleviate suffering in the future. Despite advancements in treatment regimens, cancer death rates have continued to rise due to factors like lack of vaccines and cancer recurrence in recovered patients, necessitating the exploration of new strategies for more effective therapy.

DRUG DEVELOPMENT RESEARCH (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

The Rational Design and Biological Mechanisms of Nanoradiosensitizers

Hainan Sun et al.

NANOMATERIALS (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Regulatory Mechanisms of Somatostatin Expression

Emmanuel Ampofo et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

添加到收藏夹

Review Oncology

Gold Nanoparticles as a Potent Radiosensitizer: A Transdisciplinary Approach from Physics to Patient

Sebastien Penninckx et al.

CANCERS (2020)

添加到收藏夹

Article Chemistry, Analytical

Bifunctional Peptide-Conjugated Gold Nanoparticles for Precise and Efficient Nucleus-Targeting Bioimaging in Live Cells

Yingying Gao et al.

ANALYTICAL CHEMISTRY (2020)

添加到收藏夹

Review Nanoscience & Nanotechnology

Gold Nanoparticles as Radiosensitizers in Cancer Radiotherapy

Yao Chen et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Precise design strategies of nanomedicine for improving cancer therapeutic efficacy using subcellular targeting

Xianglei Fu et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

添加到收藏夹

Article Nanoscience & Nanotechnology

Folate Receptor α-Modified Nanoparticles for Targeting of the Central Nervous System

Nataliya Kuplennik et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

添加到收藏夹

Article Pharmacology & Pharmacy

SPR signals enhancement by gold nanorods for cell surface marker detection

Farzaneh Fathi et al.

BIOIMPACTS (2019)

添加到收藏夹

Review Multidisciplinary Sciences

Progress and challenges towards targeted delivery of cancer therapeutics

Daniel Rosenblum et al.

NATURE COMMUNICATIONS (2018)

添加到收藏夹

Article Biotechnology & Applied Microbiology

The role of thioredoxin reductase in gold nanoparticle radiosensitization effects

Sebastien Penninckx et al.

NANOMEDICINE (2018)

添加到收藏夹

Article Radiology, Nuclear Medicine & Medical Imaging

Somatostatin Receptor Antagonists for Imaging and Therapy

Melpomeni Fani et al.

JOURNAL OF NUCLEAR MEDICINE (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives

Thangavel Shanmugasundaram et al.

NANOSCALE (2017)

添加到收藏夹

Article Nanoscience & Nanotechnology

Peptide functionalized gold nanoparticles: the influence of pH on binding efficiency

Emma Harrison et al.

NANOTECHNOLOGY (2017)

添加到收藏夹

Review Oncology

Biological mechanisms of gold nanoparticle radiosensitization

Soraia Rosa et al.

CANCER NANOTECHNOLOGY (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Somatostatin receptor-targeted organometallic iridium(III) complexes as novel theranostic agents

Vojtech Novohradsky et al.

CHEMICAL COMMUNICATIONS (2017)

添加到收藏夹

Article Chemistry, Analytical

Flow Cytometry-Based Quantification of Cellular Au Nanoparticles

Jonghoon Park et al.

ANALYTICAL CHEMISTRY (2017)

添加到收藏夹

Article Oncology

Expression of somatostatin receptors 2 and 5 in lecirculating tumour cells from patients with neuroendocrine tumours

Alexa Childs et al.

BRITISH JOURNAL OF CANCER (2016)

添加到收藏夹

Article Biophysics

Synthesis of functionalized gold nanoparticles capped with 3-mercapto-1-propansulfonate and 1-thioglucose mixed thiols and in vitro bioresponse

F. Porcaro et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2016)

添加到收藏夹

Article Nanoscience & Nanotechnology

LET-dependent radiosensitization effects of gold nanoparticles for proton irradiation

Sha Li et al.

NANOTECHNOLOGY (2016)

添加到收藏夹

Article Tropical Medicine

Inhibitory effect of gold nanoparticles conjugated with interferon gamma and methionine on breast cancer cell line

Nastaran Mohseni et al.

ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE (2016)

添加到收藏夹

Article Toxicology

Uptake of gold nanoparticles in primary human endothelial cells

Henrik Klingberg et al.

TOXICOLOGY RESEARCH (2015)

添加到收藏夹

Article Medicine, General & Internal

Lanreotide in Metastatic Enteropancreatic Neuroendocrine Tumors

Martyn E. Caplin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

添加到收藏夹

Article Medicine, Research & Experimental

A Novel Lanreotide-Encoded Micelle System Targets Paclitaxel to the Tumors with Overexpression of Somatostatin Receptors

Nan Zheng et al.

MOLECULAR PHARMACEUTICS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Gold nanoparticles: preparation, properties, and applications in bionanotechnology

Yi-Cheun Yeh et al.

NANOSCALE (2012)

添加到收藏夹

Article Chemistry, Multidisciplinary

Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin

Sarah D. Brown et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

添加到收藏夹

Review Cell Biology

The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation

Ralph J. DeBerardinis et al.

CELL METABOLISM (2008)

添加到收藏夹

Article Materials Science, Multidisciplinary

Gold nanoparticles capped by peptides

Francesca Porta et al.

MATERIALS SCIENCE AND ENGINEERING B-SOLID STATE MATERIALS FOR ADVANCED TECHNOLOGY (2007)

添加到收藏夹

Article Chemistry, Physical

Isothermal titration calorimetry studies on the binding of amino acids to gold nanoparticles

H Joshi et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2004)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.